September 7, 2025
Los Angeles Rams wide receiver
Puka Nacua led the Rams with 10 catches on 11 targets for 130 yards in his team's 14-9 win over the Houston Texans in Week 1. Nacua had an injury scare when a blow to the helmet left his face bloodied and forced him to leave the game, but he was able to return after receiving stitches and passing concussion tests. The 24-year-old led Los Angeles in targets in his first game sharing the field with veteran wide receiver
Davante Adams, who had four catches for 51 yards on eight targets. Nacua looked every bit the part of a dominant fantasy WR1 in Week 1. He'll have an easier matchup next week against the Tennessee Titans.
--Will BradySource: ESPN.com
September 7, 2025
Arizona Cardinals quarterback
Kyler Murray did not have his most efficient game in Week 1, but he was able to do enough to lead his team to a 20-13 victory over the New Orleans Saints. Murray was 21 of 29 for 163 yards and two touchdowns as a passer and added 38 yards on seven rush attempts. The seven rush attempts could be considered a positive sign for fantasy managers hoping Murray would use his legs more in 2025. Murray rushed more than seven times in a single game just once in 2024. The 28-year-old profiles as a low-end fantasy QB1 and has a favorable matchup next week at home against the Carolina Panthers.
--Will BradySource: ESPN.com
September 7, 2025
San Francisco 49ers running back
Christian McCaffrey was the central focus of his team's offense in a 17-13 49ers' win over the Seattle Seahawks in Week 1. McCaffrey rushed 22 times for 69 yards and caught nine passes for 73 yards, a comforting sign for fantasy managers who might have been worried that a lingering calf issue would lead to San Francisco limiting his touches early in the season. The 49ers lost two offensive weapons in
George Kittle (groin) and
Jauan Jennings (shoulder) during the game. If Kittle and Jennings miss time going forward, San Francisco could be forced to lean on McCaffrey just as heavily in the weeks to come. As long as he's on the field, he's a must-start fantasy running back with game-breaking upside.
--Will BradySource: ESPN.com
September 7, 2025
Jacksonville Jaguars running back
Travis Etienne Jr. had a monster game in his team's 26-10 Week 1 victory over the Carolina Panthers. Etienne Jr. rushed 16 times for 143 yards and added three catches for 13 yards as well. It wasn't clear coming into the season how Jacksonville would split backfield work between running backs Etienne Jr.,
Tank Bigsby,
Bhayshul Tuten, and
LeQuint Allen Jr. However, it was Etienne Jr. who dominated touches in Week 1. His 16 carries were almost double what Jacksonville's other three backs earned combined (nine). Allen Jr. was also the only other Jaguars running back to earn a target, so Etienne Jr. looks like he could be in line for a three-down role. As long as he continues to work in a clear lead role, Etienne Jr. could provide fantasy RB2 production going forward.
--Will BradySource: ESPN.com
September 7, 2025
Indianapolis Colts wide receiver
Michael Pittman Jr. caught six of eight targets for 80 yards and one touchdown during Sunday's Week 1 win over the Miami Dolphins. Although tight end
Tyler Warren led the team in targets and catches, Pittman led the team in receiving yards and was also the only Colt to catch a touchdown pass on Sunday. He was one of several Colts players to exceed their fantasy projections amidst a staggering 33-8 Indianapolis victory. Pittman benefited from playing against a subpar Dolphins defense, and things could get more difficult for him next week against the Denver Broncos. Nevertheless, Pittman's strong start to the season puts him in the low-end WR2 conversation for fantasy football going forward.
--Andersen PickardSource: RotoBaller
September 7, 2025
Washington Commanders quarterback
Jayden Daniels completed 19 of his 30 pass attempts for 233 yards, one touchdown, and zero interceptions during Sunday's Week 1 win over the New York Giants. He also rushed for 68 yards on 11 attempts. While Daniels only had the one touchdown, it was still a solid day for him in terms of rushing production and playing turnover-free football. Last year's No. 2 pick opened the 2025 season on an impressive note, but his competition will get tougher next week when he faces the Green Bay Packers, led by newcomer Micah Parsons. Green Bay's defense just held Detroit to 13 points, of which seven came during garbage time. Daniels still ranks as a mid-range QB1 thanks to his rushing ability.
--Andersen PickardSource: RotoBaller
September 7, 2025
New York Jets wide receiver
Garrett Wilson caught seven of his nine targets for 95 yards and one touchdown during Sunday's Week 1 loss to the Pittsburgh Steelers. His touchdown came on a big 33-yard strike from
Justin Fields in their first game together. Wilson's big game should excite fantasy managers going forward. There was no question that Wilson is an impact receiver with big upside, but it was a little unclear what his role would look like in a Fields-led offense. Now, we have our answer, and it's exciting. Wilson remains a high-end WR2 with legitimate WR1 upside heading into next week's game against the Buffalo Bills.
--Andersen PickardSource: RotoBaller
September 7, 2025
New York Giants head coach Brian Daboll refused to name
Russell Wilson as the team's starting quarterback for Week 2 against the Dallas Cowboys. Speaking after the team's season-opening loss to the Washington Commanders, Daboll would not give any indication whether he was leaning toward starting Wilson or rookie
Jaxson Dart moving forward. Wilson turned in a subpar performance Sunday, completing just 17 of his 37 pass attempts for 168 yards, zero touchdowns, and zero interceptions. He also rushed for 44 yards and fumbled (but recovered it himself). While Wilson did play turnover-free football, he struggled to move the Giants down the field, ultimately executing zero touchdown drives and two field goal drives. It was previously reported that the Giants would feel comfortable giving Dart snaps as early as Week 1 if necessary, so perhaps he'll get onto the field sooner than we initially expected. Regardless of which New York quarterback starts next week, they'll rank as a QB3 in fantasy football.
--Andersen PickardSource: Jordan Raanan
September 7, 2025
Atlanta Falcons wide receiver
Drake London (shoulder) is day-to-day after being diagnosed with a shoulder sprain, according to NFL Network's Ian Rapoport. He exited in the fourth quarter of Sunday's loss to the Tampa Bay Buccaneers, finishing the contest with 15 targets, eight catches, and 55 yards. London will have more diagnostic tests, but the Falcons believe that their No. 1 receiver avoided a potentially serious injury. This is good news for Atlanta, which will strongly benefit from having him available in a potential high-scoring affair against the Minnesota Vikings next week. There's also a chance that
Darnell Mooney (shoulder), who missed Sunday's game, could return in Week 2 alongside London. Unless we get an unfavorable update on London's status, he should be treated as a low-end WR1.
--Andersen PickardSource: Ian Rapoport
September 7, 2025
San Francisco 49ers tight end
George Kittle (hamstring) and wide receiver
Jauan Jennings (left shoulder) will undergo MRIs and additional testing over the next 24 hours, according to Nick Wagoner of ESPN. Both players departed Week 1 with their respective injuries, leaving the 49ers short-staffed in the passing game. Fantasy managers should pay close attention to additional updates from the 49ers organization on Monday. In the event that neither Kittle nor Jennings can play next week, players like
Ricky Pearsall,
Russell Gage Jr., and
Luke Farrell would earn increased targets.
--Andersen PickardSource: Nick Wagoner
September 7, 2025
San Francisco 49ers head coach Kyle Shanahan said that he will "get on the plane and evaluate" the kicker position after
Jake Moody went 1-for-3 on field goal attempts Sunday. One of his kicks was blocked, while the other hit off the left upright from just 27 yards out. Moody's struggles are nothing new, as he went 2-for-6 on field goals over his final three games in 2024. Of course, that means Moody is now just 3-for-9 on field goals over his last four regular-season games dating back to last year. Finding an effective field goal kicker in free agency isn't easy, but the 49ers could soon get desperate if Moody's struggles continue. Shanahan's comments indicate that the Niners aren't committed to replacing the 25-year-old, but they'll at least do their due diligence.
--Andersen PickardSource: RotoBaller
September 7, 2025
Tampa Bay Buccaneers quarterback
Baker Mayfield completed 17 of his 32 pass attempts for 167 yards, three touchdowns, and zero interceptions during Sunday's Week 1 win over the Atlanta Falcons. He also led the team with 39 rushing yards. Although Mayfield posted an abnormally low yardage total and low completion percentage, he excelled otherwise, playing turnover-free football and taking just one sack. All in all, it was a very rewarding day for his fantasy managers, and it even culminated in a three-point Buccaneers victory. Mayfield should continue to rank as a mid-range QB1 heading into next week's contest against the Houston Texans.
--Andersen PickardSource: RotoBaller
September 7, 2025
Washington Commanders wide receiver
Deebo Samuel Sr. caught seven of his 10 targets for 77 yards during Sunday's Week 1 win over the New York Giants. He also added a 19-yard rushing touchdown. On a team with several weapons on the offensive side of the ball, it was intriguing to see Samuel emerge as the top contributor. He had 14 more scrimmage yards than
Jacory Croskey-Merritt, five more receptions than
Terry McLaurin, and twice as many targets as
Zach Ertz. Given his prominent role, Samuel should be trusted as a low-end WR2 heading into Thursday Night Football against the Green Bay Packers.
--Andersen PickardSource: RotoBaller
September 7, 2025
Denver Broncos tight end
Evan Engram (calf) exited during the second half of Sunday's Week 1 contest against the Tennessee Titans. He is officially listed as questionable to return. At the time of his departure, Engram had caught three passes for 21 yards in his Broncos debut. This is a significant loss for Denver as Engram is the first alpha tight end they've had in quite some time. As a result, Engram's injury has a negative effect on the fantasy value of
Bo Nix, though it could lead to more targets for someone like
Courtland Sutton. Expect
Adam Trautman to operate as the Broncos' No. 1 tight end until Engram can return to action.
--Andersen PickardSource: Terry McCormick
September 7, 2025
Baltimore Ravens running back
Keaton Mitchell (coach's decision) is a healthy scratch for Sunday's Week 1 contest against the Buffalo Bills.
Rasheen Ali and
Justice Hill will operate as the Ravens' depth running backs behind
Derrick Henry. According to Jamison Hensley of ESPN, Ali was chosen to be active over Mitchell because of his special teams impact. Meanwhile,
Zay Flowers can fill Mitchell's role on jet sweeps and screens behind the line of scrimmage. He's still worth stashing in deeper dynasty leagues because he's shown flashes of potential before, but time is running out for him to make an impact at the NFL level.
--Andersen PickardSource: Jamison Hensley
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