October 10, 2025
Tampa Bay Buccaneers quarterback
Baker Mayfield (knee, arm) was removed from the injury report ahead of the Week 6 matchup against the San Francisco 49ers. Mayfield has been nursing some minor injuries, but will be fine for this weekend. Last week, Mayfield threw for a season-high 379 yards with two touchdowns and zero interceptions in the win over the Seattle Seahawks. The Bucs are banged up on offense with
Bucky Irving (foot),
Mike Evans (hamstring), and
Chris Godwin (leg) likely all out this weekend. Despite that, Mayfield will find a way to succeed and remain an elite QB1 play.
--Andy WebbSource: Pro Football Reference
October 10, 2025
Las Vegas Raiders running back
Raheem Mostert struggled to make an impact in his change-of-pace role during Week 5, totaling just 22 yards on a season-high seven touches. While the 33-year-old veteran still flashes big-play ability--highlighted by a 37-yard run against the Bears earlier this year--his current workload leaves him well outside fantasy relevance. Mostert should be viewed strictly as a handcuff to rookie standout
Ashton Jeanty, who has firmly established himself as the lead back. Still, with
Dylan Laube and
Zamir White buried on the depth chart, Mostert remains the clear next man up if Jeanty were to miss time. For now, he's best left on the waiver wire outside of deeper leagues or as insurance for Jeanty managers looking to protect one of fantasy's rising assets.
--Shaun AlbinSource: Raiders.com
October 10, 2025
Washington Commanders running back
Jacory Croskey-Merritt broke out with his best game of the season in Week 5 against the Chargers, totaling 150 yards and two touchdowns on 16 touches. The Croskey-Merritt takeover finally happened in Week 5, posting a season-high 50.9% snap share, handling 50% of the team's rush attempts, and running 31.3% of the team's routes. All marks were the highest of any Washington back in Week 5, and he delivered with a remarkable performance. For the season, he's rushed 283 yards and four touchdowns on 43 carries, averaging a league-best 6.6 yards per carry. Offensive coordinator Kliff Kingsbury provided some reason to keep the optimism in check, saying that the rookie still has "ways to go" in terms of playing without the ball in his hands. His work in pass protection has improved, but that is still an area where veteran
Jeremy McNichols is most trusted. Third-year back
Chris Rodriguez Jr. saw his lowest snap count and fewest carries in a game since becoming active in Week 5, suggesting he may be slipping back into a depth role. Croskey-Merritt should be expected to handle the bulk of the touches again in Week 6 against a Bears defense that is allowing an absurd 6.1 yards per carry and the fourth-most PPR points per game to opposing running backs. He should be fired up as a high-upside RB2 on Monday night.
--Kyle McCarthySource: RotoBaller
October 10, 2025
Las Vegas Raiders rookie running back
Ashton Jeanty continues to earn a larger role in the offense, showing off his versatility once again in Week 5 against the Colts. Jeanty drew seven targets, catching five passes and racking up 109 total yards from scrimmage despite not finding the end zone. His growing involvement as both a runner and receiver provides a strong floor for fantasy managers, especially with the Raiders offense increasingly leaning on him amid
Geno Smith's turnover issues and
Brock Bowers' absence. Heading into Week 6, Jeanty gets a dream matchup against a Tennessee Titans defense that ranks 29th against the run. With consistent usage and an expanding role in the passing game, Jeanty should be viewed as a strong RB2 with RB1 upside in PPR formats and a must-start in all standard leagues.
--Shaun AlbinSource: Raiders.com
October 10, 2025
Buffalo Bills tight end
Dalton Kincaid (oblique) is dealing with an oblique injury and was limited in practice for the second straight day this week on Friday. Kincaid was seen wearing a no-contact jersey in practice on Thursday and again had his reps limited in practice on Friday, putting his status up in the air for Monday night's game against the Atlanta Falcons. If the 25-year-old doesn't go full in practice on Saturday, he could draw a questionable tag going into Monday's contest. Kincaid has already scored a career-high three times in his first five games in 2025 and is coming off his first 100-yard game in the Week 5 loss to the New England Patriots. As long as he's active, Kincaid should be considered a top-10 fantasy tight end, but a questionable tag this week could make for a difficult decision for fantasy managers in Week 6.
Dawson Knox would be in play as a TE2 streamer if Kincaid is unable to play this week.
--Keith HernandezSource: Buffalo Bills PR
October 10, 2025
Las Vegas Raiders quarterback
Geno Smith continues to struggle, watching his fantasy stock take another major hit after tossing multiple interceptions against the Colts. Smith now leads the league with nine picks, a troubling trend that has tanked his reliability in all fantasy formats. With tight end
Brock Bowers sidelined and the offense shifting focus toward rookie running back
Ashton Jeanty, Smith has fallen to QB24 in overall rankings, rendering him unstartable in standard leagues. While a Week 6 matchup against Tennessee's 21st-ranked pass defense might appear favorable, the Titans' opportunistic secondary--boasting a 10.9% turnover rate--poses a real threat to Smith's chances of rebounding. Fantasy managers should look elsewhere until Smith proves capable of protecting the football and reigniting an offense that has lost its rhythm.
--Shaun AlbinSource: Raiders.com
October 10, 2025
Green Bay Packers kicker
Brandon McManus (quadriceps) is listed as questionable to play in Week 6 on Sunday against the visiting Cincinnati Bengals at Lambeau Field, according to Wes Hodkiewicz of Packers.com. However, despite his questionable status after injuring his quad in practice on Wednesday, McManus told reporters on Thursday that, "I plan on playing." The veteran field-goal kicker felt a "tug" in his quad while warming up for field goals on Wednesday. The 12th-year kicker was limited in all three practices this week. McManus appears to be on the right side of questionable, but fantasy managers will still want to check Sunday's lineup to see if he's active. The 34-year-old will be a little riskier in fantasy lineups because of his injury, but if active, he deserves to be started against a soft Bengals defense. McManus has gone 7-for-9 on field goals and 11-for-12 on extra points in his first four games of 2025.
--Keith HernandezSource: Packers.com - Wes Hodkiewicz
October 10, 2025
Washington Commanders quarterback
Jayden Daniels returned to action in Week 5 against the Chargers after missing two games with a knee injury. Daniels didn't miss a beat in Washington's road win in Los Angeles, completing 15 of 26 passes for 231 yards and a touchdown while adding 39 yards on the ground on eight rushes. The second-year quarterback was a bit rusty on his first couple of drives, but quickly settled in and looked like the same dynamic player that took the league by storm last year with one of the best rookie quarterback seasons of all time. Daniels and Washington will face the Bears off a bye in Week 6 in a rematch of their memorable game last season, which dramatically ended on a Hail Mary. It's an exploitable matchup versus a Chicago defense that is allowing nearly 30 points per game and a league-worst 6.7 yards per play. Daniels will rank as the top quarterback in fantasy in what could be a shootout on Monday night.
--Kyle McCarthySource: RotoBaller
October 10, 2025
Chicago Bears tight end
Colston Loveland (hip) was a limited participant during Friday's practice session. This is now back-to-back limited practice sessions for Loveland after he missed Week 4 due to a hip issue. The rookie tight end had all last week to rest because of the bye, but is still battling a lingering hip problem. He'll get another chance to practice on Saturday ahead of the Monday night matchup against the Washington Commanders. When healthy, Loveland hasn't done much on the field this season. He has three receptions for 43 yards heading into this Week 6 matchup. Loveland isn't someone that needs to be started in fantasy leagues at the moment.
--Andy WebbSource: Bears PR
October 10, 2025
Washington Commanders running back
Chris Rodriguez Jr. (calf) was unable to practice on Friday. This marks back-to-back days that Rodriguez has been sidelined due to a lingering calf injury. He'll get one more chance to practice on Saturday ahead of the Monday night matchup against the Chicago Bears. If he sits,
Jacory Croskey-Merritt should see his role increase in the backfield. The rookie back rushed for 111 yards with two touchdowns on 14 attempts in Week 5. He could see more carries if Rodriguez is unable to play.
--Andy WebbSource: Washington Commanders
October 10, 2025
Washington Commanders wide receiver
Deebo Samuel Sr. (heel) was a limited participant during Friday's practice session. After sitting out on Thursday, Samuel was back on the field on Friday. Fantasy managers shouldn't be too concerned as the Commanders were just resting Samuel on Thursday. He's dealing with a minor heel issue, but that shouldn't impact his status for the Monday night matchup against the Chicago Bears. Fellow wideout
Terry McLaurin (quad) is still banged up, so Samuel should be a fine WR2 for Week 6.
--Andy WebbSource: Washington Commanders
October 10, 2025
Atlanta Falcons wide receiver
Darnell Mooney (hamstring) was unable to practice on Friday. Mooney made an early exit during the Week 4 matchup versus the Washington Commanders. The 27-year-old was off last week due to a bye, but still remains uncertain to play in the Monday night matchup against the Buffalo Bills. He was a non-participant for the second straight day on Friday. He hasn't been ruled out yet, but fantasy managers should prepare to be without Mooney in Week 6.
Drake London hauled in eight receptions for 110 yards with a touchdown in Week 4. He figures to be the primary focal point on offense without Mooney. Also,
Kyle Pitts Sr. and
Casey Washington should have increased roles.
--Andy WebbSource: Marc Raimondi
October 10, 2025
Detroit Lions tight end
Brock Wright has just five catches for 37 yards on six targets so far this season, but two of his catches have resulted in touchdowns. The 27-year-old plays a consistent role in the Lions' offense, as he's played at least 40% of the team's offensive snaps in four out of five games this season. However, Wright's primary usage will likely be as a blocker as long as top Lions tight end
Sam LaPorta remains healthy. In 63 career games played for Detroit, Wright has recorded 61 catches for 561 yards and 11 touchdowns. Wright and the Lions have a difficult matchup in Week 6 against the Kansas City Chiefs, who have allowed the ninth-fewest passing yards (999) and the fourth-fewest number of passing touchdowns (five) in the NFL so far this season. Wright should remain off the radar of fantasy managers in Week 6.
--Will BradySource: RotoBaller
October 10, 2025
The Detroit Lions' defense has been highly productive over the past two weeks against the Cleveland Browns and Cincinnati Bengals, allowing a combined total of 34 points while recording five interceptions, five sacks, and a fumble recovery. The matchup will get significantly more difficult in Week 6 against the Kansas City Chiefs. Kansas City has scored 65 points over its last two games, and quarterback
Patrick Mahomes has thrown for 588 yards and five touchdowns in that span. Additionally, Detroit will be without starting cornerbacks D.J. Reed (hamstring) and Terrion Arnold (shoulder), and could be missing starting safeties Kerby Joseph (knee) and Brian Branch (ankle). The Lions' defense may have some success against a Chiefs running game that has struggled this season, but Detroit is at major risk of getting gashed through the air. The Lions D/ST should be avoided by fantasy managers where possible in Week 6.
--Will BradySource: RotoBaller
October 10, 2025
Los Angeles Rams tight end
Tyler Higbee (hip) doesn't carry an injury designation into Sunday's Week 6 contest against the Baltimore Ravens. Higbee will be back in action after missing Week 5 and being a limited participant in practice this week. Heading into Week 6, Higbee has six receptions for 62 yards and zero touchdowns. It's worth noting that Higbee could see increased playing time with
Colby Parkinson (concussion) banged up. Despite that, Higbee hasn't done enough on the field to give fantasy managers a reason to start him this weekend.
--Andy WebbSource: Adam Caplan
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