🖥 TAP TO SAVE 50% WITH CODE THANKS
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

Week 10 Start/Sit: Monday Night Football Matchup Analysis

Fantasy football start 'em, sit 'em for MNF - Week 10. Monday Night Football matchups analysis and fantasy start/sit advice for New York Giants at San Francisco 49ers

For some, it's birth. Other's may come in the form of an experience. There are even those few (my aunt) who fall in that weird, I just like their colors category. But, every sports fan has that defining moment which determines "their team". Mine came January 27, 1991 - the infamous Scott Norwood, "wide right" Super Bowl XXV. At six-and-a-half years old, I didn't know much about football -- other than it was fun to play outside with my friends and hurt sometimes -- but, my dad did. My Giants fan dad, that is, and the celebration which ensued following Norwood's botch job is one of the more memorable moments of my early childhood.

I could go into more detail, and turn this into an emotional trip down memory lane, but that's not what I'm going for here. I bring all of this up simply because that Super Bowl victory would not have been possible had the Giants not gone into Candlestick Park a week prior, kicked a million field goals, and defeated the two-time defending champion San Francisco 49ers... In their house (in case you're too young for the Candlestick reference). This was a different time. The Giants were actually good at playing football; as were the 49ers. No longer is this the case. And, when the (1-7) New York Giants head to Santa Clara to face the (2-7) San Francisco 49ers, a trip to the Super Bowl will not be at risk - they'll be playing for draft position.

This game might not have any playoff implications, and the reality is, losing would actually offer more long-term benefit. However, it's only Week 10 and these are prideful men who have a job to do - don't expect them not to come out and play. My job, then, becomes to fill you in on who you should have in your fantasy football lineups and why you should do so. Which is exactly what you'll find below. (Reading, required. Watching, optional.)

Be sure to check all of our fantasy football rankings for 2025:

 

New York Giants at San Francisco 49ers

Date and Start Time: Monday, November 12th at 8:15 p.m. EST
Game Spread: SF -3
Over/Under: 44
Notable Injuries and Status:

Offensive and Defensive Rankings (per game):

Giants 49ers
Passing Yards 9th 25th
Rushing Yards 31st 4th
Pass Defense 16th 17th
Run Defense 23rd 12th

 

Must Starts

Top Players That You Should Have In Your Lineup

Saquon Barkley (RB, NYG)

He's third among running backs in scrimmage yards. His 84.1-percent carry share (RB carries only) sits fourth at the position. He sees more targets per game than all but 13 wide receivers. He's also very good at playing football.

Odell Beckham Jr. (WR, NYG)

If you checked out that nifty table above, you probably saw that 9th next to passing yards per game, under Giants, and thought that must be a typo. It's not. In fact, Beckham's 98.1 receiving yards per game rank 6th among wide receivers. Problem is, Eli Manning has thrown just eight touchdown passes this season. (So too has Ryan Tannehill - he hasn't played since Week 5.) The 49ers have given up 11 receiving TDs to opposing WRs this season (tied for the sixth-most) so if there's a game to bet on OBJ finding the end zone, this is the one. If not, well, he's gone over 100 yards in five of his eight games.

 

Must Sits

Players To Avoid Putting In Your Lineup

Alfred Morris (RB, SF)

Remember when Jerick McKinnon went down in the preseason and everyone was all, "Alfred Morris is the man..."? That was cute. (I may, or may not, have endorsed Alf.) Not even the season-ending injury to Raheem Mostert justifies Morris being in your lineup at this point. He saw seven carries last week; he put up 13 yards. The Giants allowed 162 rushing yards in their first game without Damon Harrison, and Morris is likely to see some additional run by default, he just hasn't been effective enough at any point this season to trust that he'll capitalize on the opportunity/matchup. If he balls out on your waiver wire (he shouldn't even be on your bench) so be it... I've now seduced myself into considering rolling the dice on him in a DFS contest.

Marquise Goodwin (WR, SF)

There's one guy every week who's not really a must-sit. Not really a solid start either. But, has fantasy relevancy nonetheless. This week, that title is held by Marquise Goodwin, and I have no idea what to do with him. On one hand, Nick Mullens looked incredible. On the other hand, they played Oakland. On the other hand, Mullens attempted only 22 passes. And on the other, only four of them targeted Goodwin - he caught one for 11 yards. The Giants secondary has actually been decent, and I don't trust him. So, yeah. (see Pierre Garcon below)

Solid Options/Sleepers

Which Players Will Have Solid Games and Which Could Surprise?

Solid Option - Matt Breida (RB, SF)

Battling injury the past few weeks, Breida will have rested a full 10 days by the time this one kicks off - the Thursday night game followed by a Monday night'er couldn't have come at a better possible time. As mentioned, the Giants run D looked soft in their first game without Damon Harrison -- they're also dealing with some injuries on the linebacking front -- so Breida should be good for RB2 numbers (at a minimum) in this one... If he can stay on the field.

Solid Option - Sterling Shepard (WR, NYG)

Like Beckham, Shepard has fallen victim to Manning's allergy to throwing passes to receivers which are running (possibly standing) in the portion of the field which is painted a color that's typically not green and includes a word which delivers the home team's moniker. He does, however, offer value in this matchup due to the more than seven targets he sees per game and the fact that, again, San Fran has been rather generous in handing out receiving TDs to opposing WRs.

Solid Option - George Kittle (TE, SF)

Travis Kelce and Zach Ertz are the only tight ends averaging more receiving yards per game than Kittle's 76.9 - he's been balling. Thing is, the Giants held Ertz to 43 yards in Week 6, and only two TEs (Josh Hill and Jordan Thomas) have gone over 50 yards against this defense on the season. The 53.6 yards per game they've allowed to the position falls around the median, but another huge game from Kittle doesn't seem likely - the Giants are one of just five teams to have allowed one or fewer receiving TDs to the TE position as well. Still, 66.7-percent of Kittle's games this season have resulted in a Top-10 fantasy performance, so while the matchup might not be the greatest -- and he's dealing with a "chest" injury -- he should put up solid numbers.

Sleeper - Eli Manning/Nick Mullens (QB)

I do not believe that either of these quarterbacks has Top-10 potential. I also do not believe the final score will be 15-13 like the aforementioned 1991 NFC Championship game. Mullens was all of the rage following his impressive Week 9 debut, but when you consider that he became just the 10th QB this season to attempt 25 or fewer passes and finish the game with at least 20 fantasy points... He played Oakland. As mentioned, Eli puts up yardage, he just doesn't throw touchdowns. Both defenses have been almost identical against QBs (below) -- neither of which is overly dominant -- so I could see either QB having a decent game. I could also see them disappointing. They're in that Marquise Goodwin realm; low-end, 2-QB league options with minimal upside.

Sleeper - Pierre Garcon (WR, SF)

It's been a season to forget for Pierre Garcon. For everyone else, it's been more like forget Pierre Garcon. That was until Nick Mullens emerged from the depths of the underworld and contributed to Garcon's second-highest yardage total of 2018 -- as well as his first TD -- in the first quarter of last week's game against Oakland. The first quarter. Garcon disappeared after that, but here's to hoping it was a sign of things to come. Mullens didn't fare well on passes farther than 10 yards, and his average depth of target was just 6.6 yards (Derek Carr-ish) which tells me this Mullens-Garcon connection might wind up being something special (Garcon isn't exactly a deep-threat at this stage of his career).

Side Note: Garcon did not practice on Thursday.

Sleeper - Evan Engram (TE, NYG)

Engram is like that artist that drops a debut album so fire that you pre-order the sophomore project the moment it comes available. Then, you get the second album, and it's kinda weak but you're convinced that it can't be based on the debut so you force yourself to find reasons to like it. The reasons, in Engram's case, are the 5.2 targets per game (he saw nine last week) and the fact that he's been injured; he has to be getting healthier with each passing week, right? San Fran has allowed four receiving TDs to the TE position (tied for the eighth-most) so if Eli takes his Claritin, maybe there's a chance?

More Fantasy Football Analysis




POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Joel Embiid

Available Against Indiana
Ja Morant

Back on Friday Night
Rickard Rakell

Available Saturday
Tre Jones

is Returning on Friday
Coby White

Cleared for Action Versus Hornets
Jake Ferguson

Listed as Questionable for Week 15
Bo Horvat

Ruled Out for Saturday
Tre Johnson

to be Limited in Return on Friday
Andrei Vasilevskiy

Could Return Monday
Geno Smith

Officially Ruled Out for Week 15
Victor Hedman

to Be Out Until February
Kenny Pickett

to Start in Week 15 Against Eagles
Moussa Diabaté

Moussa Diabate Available on Friday
Jared McCann

to Miss Three Weeks With Lower-Body Injury
Tyrese Maxey

Under the Weather on Friday
Josh Jacobs

Officially Questionable to Face the Broncos
Victor Wembanyama

Expected to Return on Saturday
Stuart Skinner

Shipped to Pittsburgh
Tristan Jarry

Oilers Acquire Tristan Jarry From Penguins
Anthony Edwards

Sidelined on Friday Evening
Deebo Samuel Sr.

Questionable for Week 15
CFB

Washington State Expected to Hire Kirby Moore as Next Head Coach
CFB

Kyle Whittingham Stepping Down as Utah Head Coach
T.J. Watt

Officially Ruled Out for Monday Night
Manel Kape

Set For UFC Vegas 112 Main Event
Davante Adams

to be Questionable, Expected to Play on Sunday
Brandon Royval

An Underdog At UFC Vegas 112
Rome Odunze

Questionable for Sunday
Kevin Vallejos

Set For His Third UFC Fight
Alvin Kamara

Ruled Out for Sunday
Giga Chikadze

In Dire Need Of Victory
Cesar Almeida

Set To Welcome Cezary Oleksiejczuk To The UFC
Cezary Oleksiejczuk

Set To Make His UFC Debut
Jayden Daniels

Not Cleared for Contact
T.J. Watt

Undergoes Surgery for Collapsed Lung
Maikel Garcia

Royals Agree on Five-Year Extension
Melquizael Costa

Looks To Extend His Win Streak
Morgan Charrière

Morgan Charriere Looks to Win Second Consecutive Fights
Marcus Buchecha

Looks To Bounce Back
Kennedy Nzechukwu

A Favorite At UFC Vegas 112
King Green

Returns At UFC Vegas 112
Lance Gibson jr

Lance Gibson Jr. Set To Open Up UFC Vegas 112 Main Card
Jake Ferguson

on Track to Play in Week 15
CFB

Sherrone Moore Charged with Home Invasion, Among Other Charges
Jayden Daniels

Cleared for Contact
Tee Higgins

Ruled Out Against Ravens
Marvin Harrison Jr.

Ruled Out for Week 15, Expected Back This Year
Josh Jacobs

"Feeling Pretty Good," Will Practice on Friday
Daniel Gafford

Still Unlikely to Play Friday
Brady Cook

to Get Starting Nod for Jets in Week 15
Khris Middleton

Misses Second Straight Game
Collin Sexton

Sidelined Again Versus Bulls
Tee Higgins

Absent From Practice on Friday
Coby White

On Track To Suit Up Versus Charlotte
De'Von Achane

Should Be Available Monday
Tre Jones

Expected To Play Friday Vs. Hornets
Los Angeles Chargers

Chargers to Utilize Hot-Hand Approach in Backfield Moving Forward?
Ayo Dosunmu

to Miss Friday's Game Vs. Hornets
T.J. Watt

Trending Towards Missing Week 15
CFB

Freddie Kitchens Fired from North Carolina Coaching Staff
Joel Kiviranta

Hurt in Thursday's Win
Lars Eller

Departs Early Versus Blue Jackets
Viktor Arvidsson

Makes Early Exit Against Jets
Bo Horvat

Suffers Lower-Body Injury in Thursday's Win
Oliver Ekman-Larsson

Sustains Lower-Body Injury
Roope Hintz

Exits Loss With Injury
Logan Cooley

to Miss at Least Eight Weeks
Mike Conley

Unavailable Friday
Dennis Schröder

Dennis Schroder Downgraded to Out Thursday
Anthony Edwards

Iffy to Face Warriors
Kris Murray

Makes Third Start of the Campaign Thursday
Gary Trent Jr.

Replaces Jericho Sims in Starting Unit Thursday
Jarrett Allen

to Remain Sidelined Friday
Ryan Leonard

to Miss 3-4 Weeks
Mats Zuccarello

Lands on Injured Reserve
Timo Meier

Takes Leave of Absence
Thatcher Demko

Back in Canucks Crease Thursday
Josh Norris

Out on Thursday
Boone Jenner

Rejoins Blue Jackets Lineup Thursday
Victor Hedman

Placed on Injured Reserve
CFB

Bryce Underwood Could Leave Michigan Without Buyout
Fernando Tatis Jr.

Padres Not Considering Trading Fernando Tatis Jr.
Tarik Skubal

Tigers Engaged in "Serious Talks" Around Trading Tarik Skubal at the Winter Meetings
CFB

Chris Brazzell II Declaring for NFL Draft
CFB

Fernando Mendoza Named AP College Football Player of the Year
Raisel Iglesias

to Remain the Braves Closer
Robert Suarez

Agrees on Three-Year Deal With Braves
CFB

Sherrone Moore Remains in Police Custody
CFB

Joe Klanderman Joining Baylor Coaching Staff
CFB

Kentucky Hiring Jay Bateman as Next Defensive Coordinator
Si Woo Kim

Closes 2025 With Strong Finish Among Putting Woes
Akshay Bhatia

Looks to Rebound in 2026 After Down Year Off the Tee
Brian Harman

2025 Season a Step Back Despite Spring Win
Sam Burns

' Elite Putting Headlines a Solid 2025 Season
Sepp Straka

Ends Stellar 2025 Campaign on a High Note
Robert MacIntyre

Closes Out a Steady 2025 Campaign
CFB

Chip Kelly Interviews for Georgia Tech Offensive Coordinator Job
CFB

Louisville Receiver Chris Bell has a Torn ACL
Min Woo Lee

Breaks Through to Win in Texas This Year
PGA

Alex Noren Wins Twice on European Tour This Year
Wyndham Clark

has Up-and-Down 2025 Golf Season
CFB

Michigan Fires Head Coach Sherrone Moore
Corey Conners

Comes Close to Winning Again in Very Good 2025
Justin Rose

Turns Back the Clock in 2025
CFB

Jim Knowles Expected to be Hired as Tennessee's Defensive Coordinator
Harris English

Enjoys Solid Finish at Hero World Challenge
CFB

Defensive Coordinator Jim Knowles Not Being Retained at Penn State
CFB

Indiana's Stephen Daley Done for Season After Post-Game Injury
Pete Alonso

Orioles Finalizing Five-Year Deal
Kyle Finnegan

Tigers, Kyle Finnegan Agree on Two-Year Deal
Bo Bichette

Red Sox Out on Bo Bichette For Now
Philadelphia Phillies

Phillies Extend Manager Rob Thomson Through 2027 Season
Michael King

the Mets' Top Rotation Target?
Ronald Acuña Jr.

Ronald Acuna Jr. Could Move Back to Leadoff Spot
CFB

Florida, Wisconsin Among Suitors for QB Transfer Kenny Minchey
CFB

Bryan Harsin, Justin Wilcox Candidates for Washington State Head Coach Job?
Edwin Díaz

Edwin Diaz Agrees to Deal With the Dodgers
Kyle Schwarber

Returning to Phillies on Five-Year Deal
CFB

Ole Miss Hiring John David Baker as Offensive Coordinator
CFB

Ty Howle the Top Target for Virginia Tech Offensive Coordinator Job
Shohei Ohtani

to be Used More as Traditional Starting Pitcher Next Year
Yordan Alvarez

to Become Full-Time DH in 2026?
Mason Miller

Padres Plan to Keep Mason Miller in the Bullpen
Ranger Suárez

Orioles Interested in Signing Ranger Suarez
Anthony Volpe

Yankees Don't Expect Anthony Volpe to be Ready in April
Gerrit Cole

Targeting a Return in May/June
CFB

Heisman Trophy Finalists Announced on Monday
Rory McIlroy

Ends 2025 as the Year's Most Unburdened Player
Aaron Rai

Needs to Figure Out Putting Woes This Offseason
Jordan Spieth

Plays Better on Paper in 2025 Than Results Show
PGA

Chris Gotterup Needs to Find Better Touch and Consistency This Offseason
Hideki Matsuyama

Ends 2025 Season With a Bookend Victory
Scottie Scheffler

Comes Up Just Shy of Hero World Challenge Victory
Merab Dvalishvili

Drops A Decision At UFC 323
Petr Yan

Reclaims Bantamweight Title
Alexandre Pantoja

Era Ends With Gruesome Injury
Joshua Van

Becomes Second-Youngest UFC Champion
Brandon Moreno

Suffers His First TKO Loss
Brandon Moreno

Tatsuro Taira Becomes First Fighter To Finish Brandon Moreno
Henry Cejudo

Payton Talbott Retires Henry Cejudo
Henry Cejudo

Retires After UFC 323 Loss
Jan Blachowicz

Bogdan Guskov Vs. Jan Blachowicz Ends In A Majority Draw
San Francisco Giants

Jeff Kent Elected to Baseball Hall of Fame
Ketel Marte

Red Sox Interested in Trading for Ketel Marte

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP