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Arizona Cardinals quarterback Jacoby Brissett took first-team reps during Thursday's practice as Kyler Murray (foot) missed his second straight session. Murray's injury appears to be affecting his mobility, and the team may be preparing to roll with Brissett under center for Sunday's matchup against the surging Indianapolis Colts. Brissett last started in 2024 with the New England Patriots, going 1-4 while averaging 5.1yards per attempt. While the veteran brings stability and experience, he lacks the dynamic upside Murray provides both as a passer and runner. Fantasy managers should avoid Brissett outside of deep superflex leagues, as the Cardinals offense faces a difficult challenge on the road against an Indianapolis defense that ranks near the top of the league in takeaways and sacks.--Shaun Albin
Source: Tyler Drake
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