DraftKings CFB DFS Lineup Picks: Week 10 Daily College Fantasy Football - Saturday Main Slate (11/5/22)

Mike's DraftKings daily fantasy college football lineup picks for the Saturday Main Week 10 (11/5/22) slate. His CFB DFS lineup picks and DFS sleepers will help you win.

We have our largest slate of the season so far with 14 games going on for the main slate. There are some big ones on here! We get started with Florida in College Station and Kentucky heading up to Missouri. Texas Tech heads to Ft. Worth to take on the streaking Toadies. North Carolina heads to Virginia. We have Minnesota in Nebraska and Ohio State heading to Evanston. We close out the noon kicks with Tulane in Tulsa.

Baylor and Oklahoma kick off in Norman at 3pm Eastern. The normal 3:30 kickoff window has Oregon in Boulder. Syracuse heads down to Pittsburgh. Penn State goes over to Bloomington. Central Florida heads to the Liberty Bowl to take on Memphis. Then we have the huge game between Tennessee and Georgia in Athens.

In this article, I will be providing you with my daily fantasy college football lineup picks for DraftKings on 11/5/22 locking at noon eastern. I’ll provide multiple player suggestions for players at quarterback, running back, and wide receiver, aiming to highlight one option at the high, middle, and lower end of the salary scale. Good luck, RotoBallers.

DraftKings CFB DFS Picks - Quarterbacks

Bo Nix, Oregon ($9,600)

Ho-hum, Nix scored another six touchdowns (three rushing) last week. It has become a weekly occurrence. Nix has at least 35 DraftKings points in every FBS game since the disastrous start against Georgia. He's the surest thing going right now. Colorado isn't going to hold him under that mark. This feels like closer to a ceiling game than a floor game against the Ralphies.

Jalon Daniels, Kansas ($7,400)

Daniels was warming up for the Jayhawks against Baylor two weeks ago, so he should be good to go here. Jason Bean filled in nicely, but Daniels will rack up a bunch of rushing yards as well against an Oklahoma State defense that got shredded last week. If Spencer Sanders misses this game, that Oklahoma State defense could be on the field a lot more than they want to be. I like Daniels a lot in this price range if he plays as expected. If not, I'll use Bean at just $300 less.

Mikey Keene, Central Florida ($6,700)

John Rhys Plumlee suffered what was about 99.9% likely to be a concussion last week and was unable to return. As per usual, the college coaches are no help when it comes to injury statuses. However, since the Tua Tagovailoa incident in the NFL, every team has been very careful with concussions across both leagues. Most players miss at least one game now, so I'm expecting Keene to be the guy against Memphis. Keene put up good numbers in leading the come-from-behind win over Cincinnati last week. I like him starting at this price with JRP likely sidelined.

Blake Shapen, Baylor ($6,100)

I still don't trust the Oklahoma defense. Hunter Dekkers put up good numbers last week despite a couple of untimely interceptions. The Bears have been content to run teams into submission with positive game scripts the past couple of weeks. That has dropped the price on Shapen. If you look back to the West Virginia and Oklahoma State games where Baylor had to throw to keep up, Shapen put up some good numbers in this price range. He'll be close to a ceiling game here.

Also consider: C.J. Stroud, Ohio State ($9,100); Max Duggan, TCU ($8,500); Brennan Armstrong, Virginia ($7,100); Michael Pratt, Tulane ($6,300); Conner Weigman, Texas A&M ($5,400)

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DraftKings CFB DFS Picks - Running Backs

Mohamed Ibrahim, Minnesota ($7,300)

Yes, Nebraska's defense has improved by leaps and bounds since earlier in the season, but teams can still run on them. Chase Brown had a big game last week and Devin Mockobee was the guy the week before. Ibrahim is a lock for triple digits, and he has six rushing touchdowns in three career games against Nebraska. Triple digit yardage and a pair of touchdowns make Ibrahim well worth the price.

Kendre Miller, TCU ($6,300)

Yeah, Duggan having an outstanding season is a big reason for TCU's success, but don't overlook Miller again. He has five 100-yard rushing games in the last six games and has scored at least one touchdown in every game this season. His speed has been a problem for everyone so far. We saw Baylor run wild on the Red Raiders last week in Lubbock. There is no reason Miller and the Toadies won't do the same.

Richard Reese, Baylor ($6,000)

As you can tell, I really love the middle tier of backs this week. Can you blame me? Reese has 33 and 39 touches over the last two games and has turned that into 78.2 DraftKings points. He will be able to keep that going against an Oklahoma defense that still misses too many tackles and takes too many wrong angles. If Reese is going to get 30 touches again, he has slate-breaking potential.

Devon Achane, Texas A&M ($5,500)

Kentucky is the only team that hasn't run for 150 yards on the Gators and Florida has allowed at least one rushing touchdown in every game this season. Achane was heavily involved in the improved A&M offense last week, hauling in seven passes for the second consecutive game and topping 100 yards for the first time in three games. He's too cheap in this matchup.

Also consider: Israel Abanikanda, Pittsburgh ($7,700); TreVeyon Henderson, Ohio State ($6,400); Tyjae Spears, Tulane ($6,100); Bucky Irving, Oregon ($5,800); Kaytron Allen, Penn State ($4,900); Deion Smith, Colorado ($3,600)

DraftKings CFB DFS Picks - Wide Receivers

Jalin Hyatt, Tennessee ($7,100)

The return of Cedric Tillman didn't diminish Hyatt's output last week. He still scored multiple touchdowns for the fourth consecutive game and topped 100 yards for the third straight game. Hyatt now has 11 touchdowns in the last four games. You know the Vols are going to feed Hyatt as much as they possibly can. Can Georgia cover both Hyatt and Tillman? It's going to be a chore and I don't think they shut them both down. I will ride the hot hand with Hyatt.

Brock Bowers, Georgia ($6,700)

Bowers went berserk at the Cocktail Party last week. The lack of consistency within a Georgia team with so many weapons is a concern, but the Tennessee defense has struggled in pass defense this year. They locked down Kentucky, but they won't be able to harass Bennett like they did with Will Levis last week. Prior to that, Tennessee had allowed more than 300 passing yards in every SEC game this year. If Georgia does it, Bowers will be a big reason why.

Antoine Green, North Carolina ($6,000)

Josh Downs is still the guy to have if you can afford him. If not, Green is a nice consolation prize. Green has 292 receiving yards and three touchdowns in the last two games. Defenses have been paying more attention to Downs, which frees up more opportunities for Green. Drake Maye isn't going to quit flying the friendly skies anytime soon. He's a strong play against a Virginia team that still can't move the ball on offense.

Moose Muhammad III, Texas A&M ($4,700)

Moose quickly became Weigman's favorite target last week. He wound up with eight receptions for 112 yards and a touchdown. Considering the way A&M's offense moved the ball, I would be very shocked if anyone but Weigman starts this game. Moose is priced to sell and he really shouldn't be. He doesn't even need to take the top off of the Florida D to hit value at this price.

Also consider: Marvin Harrison Jr., Ohio State ($7,500); Parker Washington, Penn State ($6,400); Evan Stewart, Texas A&M ($6,000); Dominic Lovett, Missouri ($4,900); Julian Fleming, Ohio State ($4,900); Daniel Jackson, Minnesota ($4,100)

College Football DFS Game Stack Options

You know which team stacks are often good, but this isn't baseball. Game stacks can and do work. Just look at Alabama-Tennessee in Week 7. That game made several DFS players a few thousand bucks. Who can do that this week? Let's check it out!

Florida at Texas A&M

I don't necessarily think that this will be the highest-scoring stack, but it will definitely be the most attainable and the one that leaves you with enough left to use Ibrahim against Nebraska. Most of the A&M pieces are underpriced. Weigman/Achane/Moose are musts and Evan Stewart still feels cheap as well. Anthony Richardson has a nice floor thanks to his rushing ability and he has had a couple of big games this year, so there is a nice ceiling there. Trevor Etienne remains too cheap. Xavier Henderson is probably the Florida receiver you want, but if I run this stack, I won't be using a WR for the Gators. They should have better luck on the ground.

Texas Tech at TCU

I'm a little nervous about this one with the way Tech looked against Baylor last week. I like the TCU side a lot more with Duggan, Miller, and Quentin Johnston the top priorities and all worth using together. Taye Barber is a good way to differentiate the stack instead of Johnson. Behren Morton was nearly benched last week, and could be in this game if things go poorly for Tech. I like both Tahj Brooks and Sa'Rodorick Thompson, but the receivers are still a crapshoot. I like the game-breaking ability of Xavier White, but I can't argue with Myles Price either.

Honorable Mention: Baylor at Oklahoma, Tennessee at Georgia

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