Who Should I Start for Week 6? Fantasy Football outlooks for Daniel Jones, Patrick Mahomes, Dak Prescott, Baker Mayfield, Justin Herbert, Trevor Lawrence, Tua Tagovailoa, Geno Smith, Bryce Young, Jordan Love.
Who Should I Start? Who Should I Sit? Some of the most common Week 6 fantasy football lineup decisions involve players like Daniel Jones, Patrick Mahomes, Dak Prescott, Baker Mayfield, Justin Herbert, Trevor Lawrence, Tua Tagovailoa, Geno Smith, Bryce Young, Jordan Love. However, don't worry, we are here to help you make these decisions and build winning lineups in Week 6. Set your optimal fantasy football lineups for Week 6 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
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Fantasy Football Matchup Outlooks
Below are some fantasy football outlooks written by our NFL team here at RotoBaller, bringing you their fantasy football analysis and advice on which players to consider starting in Week 6:
Patrick Mahomes, QB, Kansas City Chiefs
Kansas City Chiefs quarterback Patrick Mahomes completed 29 of 41 passes for 318 yards with one touchdown and one interception, while adding 60 yards and a touchdown on six carries in Monday night's 31-28 loss in Jacksonville. Mahomes threw the most times of any game this season and eclipsed 300 yards passing for the first time since Christmas Day last year against the Steelers.
In addition, Mahomes has been running more often and more effectively this season, leading the Chiefs in rushing in three of five games. He's topped 57 rushing yards in three of five games this season after reaching that mark just four times in his career before this year. Mahomes and the Chiefs fell to 2-3, but there are at least some encouraging signs with the offense, and star receiver Rashee Rice will be back from his suspension soon.
Mahomes carries solid QB1 upside in all leagues heading to a potential shootout against the Detroit Lions.
Justin Herbert, QB, Los Angeles Chargers
Los Angeles Chargers quarterback Justin Herbert had his worst game of the season, completing 22 of 29 passes for 166 yards, one touchdown, and one interception in the team's 27-10 loss to the Washington Commanders. The offense looked disorganized, burdened by costly penalties and sloppy play for most of the afternoon. Herbert also led the team in rushing with four carries for 60 yards, showing how often he was pressured behind a depleted offensive line.
Herbert has been hit 35 times in the last three games, as a wave of injuries on the offensive line continues to mount. As the team prepares for Week 6 against a struggling Miami Dolphins defense, the Chargers might need to rely more on the passing game since they just placed rookie running back Omarion Hampton (ankle) on IR.
Herbert should have a chance to bounce back against a struggling Miami secondary on Sunday.
Geno Smith, QB, Las Vegas Raiders
ESPN's Jeremy Fowler says he would classify the Las Vegas Raiders as "mildly concerned" about quarterback Geno Smith's rough start to the season. Fowler adds that there's "no sentiment that Smith is a broken quarterback." Smith is not expected to be benched in Week 6 against the Tennessee Titans. Scouts that Fowler has talked with think Smith has "been too late" with the ball and is relying on his arm talent to force footballs into tight windows.
It hasn't been pretty for the veteran QB through five games, as he's thrown six touchdowns and a league-leading nine interceptions. Smith and head coach Pete Carroll have enough equity from their days in Seattle that Carroll "could stick with him a little longer as a result."
With that said, real questions are going to arise about Smith's job status if he cannot get the job done on Sunday against the one-win Titans. He is best to fade in all one-QB leagues in Week 6.
Baker Mayfield, QB, Tampa Bay Buccaneers
Tampa Bay Buccaneers quarterback Baker Mayfield completed 29 of 33 pass attempts for 379 yards, two touchdowns, and zero interceptions during Sunday's Week 5 win over the Seattle Seahawks. He also took one sack and rushed for 15 yards. Mayfield played clean, turnover-free football while maintaining a terrific 87.9 percent completion rate and leading his Bucs to a win.
The 30-year-old has been a top-10 fantasy quarterback once again this season, posting 18+ fantasy points in all five games so far, as well as 23+ fantasy points in three of five. He should continue to be started in all fantasy leagues ahead of next week's game against the San Francisco 49ers as a high-end QB1.
Tua Tagovailoa, QB, Miami Dolphins
Miami Dolphins quarterback Tua Tagovailoa (hip, thumb) was a limited participant during Wednesday's practice session. Tagovailoa apparently suffered a hip and left thumb injury during last Sunday's game against the Carolina Panthers. The 27-year-old didn't show any signs of being injured when he threw for 256 yards with three touchdowns.
He's finally starting to turn a page with five touchdowns and zero interceptions over his last two games. Fantasy managers shouldn't be too worried about Tagovailoa for Sunday's game against the Los Angeles Chargers. It's the beginning of the week, and the Dolphins are going to be careful, especially with Tagovailoa's injury history.
At the moment, the team has expressed that Tagovailoa will not face any limitations this weekend. As a result, he carries high-end QB2 upside in a matchup against the Chargers.
Who Should I Start Tool
You can also see the Who Should I Start tool here.
Week 6 Player Decisions. Today's focus is on specific players - Daniel Jones, Patrick Mahomes, Dak Prescott, Baker Mayfield, Justin Herbert, Trevor Lawrence, Tua Tagovailoa, Geno Smith, Bryce Young, Jordan Love. These are some of the most common searches for fantasy football lineups in Week 6.
Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player name. In the second box, search for the second player name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.
Improvements For Who Should I Start? You may have noticed that our 'Who Should I Start?' tool has gotten an overhaul. We've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, stats, projections, strength of schedule, players news, and enhanced search results with data to compare with a slick new interface. We hope you enjoy!
How It Works. Each week our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.
Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do, is to select the scoring format. There are three small radio buttons (small circle), so click on the scoring format you prefer. The results may vary based on the scoring format you select.
Popular Week 6 Searches. Curious to see some tough lineup decisions for Week 6 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 6 Searches - Start/Sit Player Comparisons
Below are some popular searches and comparisons from our Who To Start tool for Week 6 for Daniel Jones, Patrick Mahomes, Dak Prescott, Baker Mayfield, Justin Herbert, Trevor Lawrence, Tua Tagovailoa, Geno Smith, Bryce Young, Jordan Love:
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