September 13, 2025
Kansas City Chiefs running back
Kareem Hunt will take on the Philadelphia Eagles at home this Sunday. Hunt received an identical workload to
Isiah Pacheco and produced similar results. The veteran back was less efficient with his carries but picked up more receiving yards in his three opportunities. It is also important to note that Hunt appeared to be the preferred back on passing downs and short yardage situations. If this usage continues, Hunt could end up being the more fantasy-relevant player in this backfield. The Chiefs deployed Hunt in goal-line situations last season, and he was successful in that role, so it's possible that he retains that job. That said, the backfield usage was split 50/50, and it will be a difficult situation to deal with unless one player starts commanding more touches. Hunt will have to face a stout Eagles defense this week, so even if he gets more work, it could be hard to get anything going. Hunt is ranked RB48 in our RotoBaller rankings this week, making him a deeper league flex option. It might be best to wait and see how this backfield shakes out.
--Joshua CostelloSource: NFL.com
September 13, 2025
Kansas City Chiefs running back
Isiah Pacheco will face the Philadelphia Eagles in Week 2. The defending Super Bowl champions defeated the Chiefs in their last matchup, and Pacheco only had seven rushing yards on three carries. The 26-year-old will have the chance to exact some revenge, but he must first overcome the timeshare he's in with
Kareem Hunt. Pacheco and Hunt had the same number of opportunities in Week 1; both handled five carries and two catches on three targets. The former ultimately finished with more total yards, but it was not an impressive performance by either back. Pacheco did manage 5.0 yards per carry when given the opportunity, so maybe he can build on that efficiency with more usage. That said, the Eagles defense was one of the toughest in the league to run against last season, and that looks to be the case again this year. Pacheco will have his work cut out for him if he wants to carve out a larger role in the Kansas City backfield. Pacheco is ranked RB35 in our RotoBaller rankings this week, making him an RB3/Flex option. He'll be a tough player to trust this week.
--Joshua CostelloSource: NFL.com
September 13, 2025
Kansas City Chiefs quarterback
Patrick Mahomes will take on the Philadelphia Eagles in Week 2 for a Super Bowl rematch. The last time these two teams matched up, the Eagles ended up taking home the Lombardi trophy.
Jalen Hurts and the gang are coming off a Thursday night win over the Dallas Cowboys in Week 1, while the Chiefs suffered a one-possession loss to the Los Angeles Chargers on Friday. The 29-year-old had a decent performance against the Chargers, passing for 258 yards and a touchdown while adding 57 yards and a score on the ground. That said, Mahomes will have the odds stacked against him on Sunday, facing one of the best defenses in the league without two of his top offensive weapons.
Rashee Rice is still serving his suspension, and
Xavier Worthy is listed as doubtful for the upcoming matchup. Despite playing at Arrowhead this weekend, Mahomes and the Chiefs are home underdogs against the Eagles. The Chiefs quarterback is ranked QB11 in our RotoBaller rankings this week, making him a fringe-QB1.
--Joshua CostelloSource: Kansas City Chiefs - Twitter
September 13, 2025
San Francisco 49ers kicker
Eddy Pineiro signed with the team on September 10, in the wake of the release of
Jake Moody. Pineiro does not have Moody's leg strength, but he is certainly more accurate. Despite attempting twice as many field goals as Moody in his career (126 to 62), Pineiro has one fewer miss (15 to Moody's 16). San Francisco's offense has been bitten by the injury bug, including quarterback
Brock Purdy (toe, shoulder), who has been ruled out for Sunday's game against the Saints. With
Mac Jones at the helm, the offense's potential takes a step back, placing greater reliance on the team's kicker to put up points, however possible. Consider Pineiro a serviceable streamer for Week 2.
--Dan StephensSource: NFL.com
September 13, 2025
San Francisco 49ers tight end
Jake Tonges was the hero of the team's Week 1 victory over the Seattle Seahawks. Tonges stepped in for an injured
George Kittle (hamstring) and caught the go-ahead touchdown with just over a minute and a half left in the game. With Kittle now on injured reserve, Tonges is now the favorite to act as San Francisco's first-string tight end. Unfortunately, quarterback
Brock Purdy (toe, shoulder) has been ruled out for the 49ers' next game, meaning
Mac Jones will be under center when they face the Saints on Sunday. Tonges had the play of the game but saw only two other targets in Kittle's stead last week. Fantasy managers looking for streaming tight end options can probably find a more reliable option on the wire for Week 2.
--Dan StephensSource: NFL.com
September 13, 2025
Wide receiver
Kendrick Bourne signed a one-year deal with the San Francisco 49ers on September 9, returning to the team that gave him his start in the NFL in 2017. The signing was in light of injuries sustained in Week 1 by key pass catchers
George Kittle (hamstring), who is now on injured reserve, and
Jauan Jennings (shoulder), who is questionable for Week 2. Quarterback
Brock Purdy (toe, shoulder) is also dealing with injuries and has been ruled out for Sunday's game against the Saints. Taking over the offense will be
Mac Jones, who was Bourne's teammate for three years in New England, from 2021 to 2023. Bourne should not be in starting lineups but could be a bench stash in deeper leagues in case he shows renewed chemistry with Jones, given Purdy might be facing a multi-week absence.
--Dan StephensSource: NFL.com
September 13, 2025
San Francisco 49ers wide receiver
Skyy Moore stands little chance of making an impact in Week 2, despite the injury bug biting key players on offense. Even though tight end
George Kittle (hamstring) is on injured reserve and wide receiver
Jauan Jennings (shoulder) is questionable for Sunday's game against the Saints, veterans
Marquez Valdes-Scantling and
Kendrick Bourne stand in Moore's way on the depth chart. Moore played just three snaps in Week 1, and even if he does see a greater run on Sunday, the offense will be helmed by
Mac Jones and not
Brock Purdy (toe, shoulder), who has been ruled out. Moore's only path to fantasy relevance is in leagues that count return yards. Last week against Seattle, he fielded one kickoff and four punts, totaling 63 return yards.
--Dan StephensSource: NFL.com
September 13, 2025
San Francisco 49ers wide receiver
Marquez Valdes-Scantling saw zero targets on 15 routes run in Week 1. With
George Kittle (hamstring) now on injured reserve and
Jauan Jennings (shoulder) tagged as questionable for San Francisco's Week 2 matchup against the Saints, it is possible that Valdes-Scantling plays a bigger role on Sunday. Unfortunately,
Brock Purdy (toe, shoulder) has been ruled out so it will be
Mac Jones under center, limiting Valdes-Scantling's upside even if he does see more playing time. MVS does have the ability to stretch the field but Jones' career completion rate on passes of 20 or more air yards is a mere 30%, effectively negating that threat. If it were Purdy running the show, Valdes-Scantling would have more potential but as it is, he has little viability in Week 2.
--Dan StephensSource: NFL.com
September 13, 2025
The New York Giants defense is a risky fantasy start for Week 2 against a potent Dallas Cowboys offense, despite a solid sack total in Week 1. While the Giants' defense recorded three sacks against Washington, including two by Brian Burns, they also allowed three touchdowns and were on the field for an extended period. They face a Cowboys offense that scored 20 points in their Week 1 loss to the Eagles and features a dynamic passing attack led by
Dak Prescott and
CeeDee Lamb. The Cowboys' offense ranked 18th overall in Week 1 with 307 total yards, and they pose a significant threat, making the Giants' Defense a high-risk, low-reward play this week.
--Danny BoilySource: NFL.com
September 13, 2025
New York Giants kicker
Graham Gano is a possible fantasy option for Week 2 against the Dallas Cowboys, depending on your league. Gano was responsible for all six of the Giants' points in Week 1, making both of his field goal attempts, including a long of 52 yards, for 8 fantasy points. This puts him in a decent position among fantasy kickers, especially since he has a 100% field goal percentage so far. His opportunities for scoring could increase against a Dallas team that gave up 11 fantasy points to kickers in Week 1 of the 2025 season. Given the Giants' offensive struggles and Gano's reliable leg, he should be considered for Week 2.
--Danny BoilySource: NFL.com
September 13, 2025
The Seattle Seahawks defense/special teams performed at a high level in Week 1 against the San Francisco 49ers. They draw the Pittsburgh Steelers in Week 2, who just hung 34 points on the New York Jets. The Steelers are riding high on that victory, but Week 2 should be a lower-scoring affair. The Seahawks' defensive unit harassed 49ers quarterback
Brock Purdy all day last weekend. They picked him off twice and realistically could have made it a third on Purdy's go-ahead touchdown pass. Many NFL fans came into this season skeptical of the Steelers' offense. Their Week 1 production was encouraging, but the Seahawks' defense looks like one of the elite units in the NFL. With a great ability to rush the passer and fantastic players in the secondary, a 41-year-old
Aaron Rodgers could struggle in this game. However, the absence of safety Nick Emmanwori (ankle) and cornerback Devon Witherspoon (knee) is notable this week, making the Seahawks D/ST check in as a borderline starting option.
--Quincy Milton III - RotoBallerSource: Brady Henderson
September 13, 2025
New York Giants quarterback
Jaxson Dart is not a recommended fantasy option for Week 2 against the Dallas Cowboys, as he is not expected to play. Although the rookie first-round draft pick has impressed in the preseason and is the team's QB2, head coach Brian Daboll has publicly stated that
Russell Wilson will remain the starter for Sunday's game. There is some speculation that Dart could see action if Wilson struggles, but given that he has no regular-season statistics for 2025, his fantasy outlook is entirely dependent on an in-game change. Therefore, Dart should be left on the bench or waiver wire for this matchup.
--Danny BoilySource: NFL.com
September 13, 2025
New York Giants tight end
Theo Johnson is not a recommended fantasy start for Week 2 against the Dallas Cowboys. He was the TE49 in fantasy football for Week 1, securing just one of his three targets for five receiving yards and one fantasy point. This meager production, despite dominating the tight-end snaps with 46, makes him an unreliable option. Furthermore, the Cowboys' defense was a difficult matchup for tight ends in 2024, ranking second in the league by allowing only 7.66 fantasy points per game to the position. Given the tough matchup and Johnson's minimal usage and production in Week 1, he should be left on the bench in all formats.
--Danny BoilySource: NFL.com
September 13, 2025
New York Giants running back
Cam Skattebo is not a recommended fantasy start for Week 2, despite facing a favorable matchup. Skattebo was the RB58 in Week 1, with a minimal role, receiving only two carries for -3 yards and two receptions for 12 yards, totaling just 1.9 fantasy points on an 11.8% timeshare. While the Dallas Cowboys' defense was the 23rd-ranked fantasy defense against running backs in 2024 and gave up 158 rushing yards in Week 1, Skattebo is simply not seeing the volume to capitalize on the opportunity. His primary role appears to be as a depth and short-yardage option behind
Tyrone Tracy Jr., which severely caps his fantasy upside.
--Danny BoilySource: NFL.com
September 13, 2025
The New Orleans Saints defense/special teams recorded five sacks and allowed 20 points in Week 1 against the Arizona Cardinals. While the sack total was a pleasant surprise, it shouldn't be expected consistently with a defensive front led by 34-year-old Cameron Jordan. They face
Mac Jones in Week 2 instead of
Brock Purdy (toe), but still have to contend with
Christian McCaffrey and remain without Chase Young (calf). Ranked 28th of 32 defenses this week, the Saints are best left off fantasy rosters.
--Dakota Legg - RotoBallerSource: RotoBaller
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