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Buffalo Bills running back James Cook III draws a difficult matchup in Week 5 against a Patriots defense that has surrendered just 77.5 rushing yards per game, tied for second-fewest in the league. While Cook may find tough sledding between the tackles, his versatility as a receiver should keep him firmly in the RB1 mix. Last week against Baltimore, he managed only 44 yards on the ground but offset that with 58 yards through the air, showing his ability to remain productive even when the rushing lanes are clogged. In what projects to be one of Buffalo's biggest games of the season, the Bills will likely lean on Cook in multiple ways to generate offense. Fantasy managers should continue to view him as a high-end starting option in both standard and PPR formats.--Shaun Albin
Source: BuffaloBills.com
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REAL-TIME FANTASY NEWS

Michael Carter

Will Play "a Lot of Snaps" in Week 5
Texas Rangers

Rangers Hire Skip Schumaker as New Manager
Trevor Megill

Ready for NLDS
Will Smith

Will be Available to Catch in NLDS
Clayton Kershaw

to Pitch Out of Bullpen in NLDS Against Phillies
Lawrence Butler

Undergoes Knee Surgery on Friday
Brandon Woodruff

Will Not Pitch in NLDS
Scott Laughton

Deemed as Week-to-Week
Jayden Daniels

to Return to Starting Role in Week 5
Logan Cooley

Expected to Be Available for Season Opener
Anton Lundell

Considered Day-to-Day
Andrei Vasilevskiy

Ready for Action Saturday
Ukko-Pekka Luukkonen

Out Week-to-Week
Bowen Byram

Available Friday
Lamar Jackson

Officially Ruled Out for Week 5
Brock Bowers

Listed as Questionable, Expected to Play in Week 5
Juwan Johnson

Listed as Questionable for Week 5
Dallas Goedert

Good to Go for Week 5
Tyjae Spears

Questionable for Week 5
George Kittle

a "Long Shot" to Play in Week 6, Week 7 Return More Likely
Devin Booker

Likely Playing on Friday
Luka Dončić

Luka Doncic Won't Play This Weekend
Tyrone Tracy Jr.

Doubtful to Play in Week 5
Josh Giddey

Returns to Full Practice
Matas Buzelis

has Team Optioned Accepted
Calvin Ridley

Questionable for Week 5
Alex Pereira

Can Become Two-Time Light-Heavyweight Champion
Magomed Ankalaev

Set For His First Title Defense
Cory Sandhagen

An Underdog At UFC 320
Merab Dvalishvili

Set For His Third Title Defense
Khalil Rountree Jr.

Returns At UFC 320
Jiří Procházka

Jiri Prochazka Returns At UFC 320
Youssef Zalal

Looks To Extend His Win Streak
Josh Emmett

Looks To Get Back In The Win Column
CeeDee Lamb

Ruled Out Again in Week 5
Joe Pyfer

Looks To Earn Top 15 Ranking
Chuba Hubbard

Officially Out for Week 5 Against Miami
Abus Magomedov

Set To Open Up UFC 320 Main Card
Mike Evans

to Miss Another Game in Week 5
Bucky Irving

Officially Ruled Out With Sprained Foot
Bucky Irving

Expected to Miss Week 5, In Danger of Missing Week 6?
Brandon Aiyuk

Still "Weeks Away" From Returning to Action
Chuba Hubbard

Not Expected to Go on Injured Reserve
J.J. McCarthy

Ruled Out for Week 5
Chuba Hubbard

Not Expected to Play on Sunday
Kendrick Bourne

Explodes for 10 Catches With Teammates Sidelined Thursday
Puka Nacua

Big Second Half Against 49ers Solidifies WR1 Ranking
Cam Schlittler

Dazzles in 12-Strikeout Performance, Yankees Advance to ALDS
CFB

Quintrevion Wisner Expected Back vs. Florida
CFB

Emmett Mosley Probable for Longhorns vs. Florida
Giannis Antetokounmpo

to Join the Bucks in Miami
Jaden Ivey

Fully Recovered From Fractured Fibula
Nick Jensen

an Option for Preseason Finale
Lars Eller

Could Be Available Saturday
Jonathan Huberdeau

Remains Under Evaluation
Jonathan Toews

Labeled as Day-to-Day
Bryan Rust

to Miss Start of Season
Niko Mikkola

Inks Eight-Year Extension With Panthers
Jackson LaCombe

Signs Largest Contract in Ducks History
OG Anunoby

Was Inactive for the Knicks' Preseason Opener
Joel Embiid

Adem Bona Starts in Place of Joel Embiid on Thursday
Dominick Barlow

Grabs 10 Boards in Abu Dhabi
Miles McBride

Leads the Knicks to an Exhibition Win in Abu Dhabi
VJ Edgecombe

Drops 14 Points in Thursday's Exhibition
Josh Hart

Injured in Exhibition
Shane McClanahan

Expected to be "Fully Ready" for Spring Training
Bo Bichette

Unlikely to be Ready for ALDS
Coby White

Does Some Shooting During Wednesday's Practice
Patrick Williams

Hurts Ankle at Practice
Mark Williams

to Sit Out Preseason Opener
Noah Clowney

Healthy and Bigger Ahead of New Season
Gabe Vincent

Logs Full Practice
LeBron James

Does Individual Work at Practice
Bogdan Bogdanović

Bogdan Bogdanovic Getting Back on Track After Partially Rupturing Hamstring
Terry Rozier

Suffers Left-Hamstring Strain
Brandon Williams

Out One Week Due to Hamstring Strain
Bryce Eldridge

to Undergo Wrist Surgery
Atlanta Braves

Brian Snitker Will Not Return as Braves Manager
Connor Ingram

Oilers Acquire Connor Ingram
Anders Lee

on Track to Play in Preseason Finale
Alex Ovechkin

Expected to Suit up Thursday
Ryker Evans

Out 6-8 Weeks With Upper-Body Injury
Ivan Demidov

Avoids Serious Injury
Luke Hughes

Agrees to Seven-Year Deal Wih Devils
Luke List

Looking to Win Again at Sanderson Farms Championship
Tom Kim

Could Be in For Long Week in Mississippi
Max Homa

Are Things Beginning to Turn Around For Max Homa Ahead of Sanderson Farms?
Nicolai Hojgaard

an Interesting Play at Sanderson Farms
Davis Thompson

Looks to Keep Momentum Going in Mississippi
Nick Dunlap

Hoping to Turn Woes Around at Sanderson Farms Championship
PGA

Matti Schmid a Volatile Option at Sanderson Farms
Thorbjorn Olesen

a Solid Play at Sanderson Farms
Stephan Jaeger

a High-Upside Play in Mississippi
Hayden Buckley

Trying to Find Form at Sanderson Farms
Ben Martin

Struggling Mightily with Golf Game
Jacob Bridgeman

Leaning on his Putter at Sanderson Farms
Lanto Griffin

Heating Up for Sanderson Farms Championship
Quade Cummins

Trying to Make Cut at Sanderson Farms
Carson Young

Aims to Rebound from Procore Championship
Matt Kuchar

Still a Golfer to Watch This Week
Doug Ghim

Trending Up for Sanderson Farms Championship
Eric Cole

May Struggle at Sanderson Farms Championship
Christiaan Bezuidenhout

Ready for Sanderson Farms Championship
J.T. Miller

Considered Day-to-Day
James van Riemsdyk

to Rejoin Team Wednesday
Mackenzie Hughes

Eyes Another Strong Week at Sanderson Farms
Andrew Putnam

a Solid Value Play in Mississippi
Tarik Skubal

Shines in Postseason Debut, Tigers Take Game 1 Over Guardians
CFB

Behren Morton To Start Against Houston Saturday
Texas Rangers

Rangers, Bruce Bochy Mutually Agree to Part Ways
Minnesota Twins

Rocco Baldelli Fired as Twins Manager
San Francisco Giants

Giants Fire Manager Bob Melvin
Francisco Alvarez

to Have Thumb Surgery in the Coming Days
Bo Bichette

Blue Jays Optimistic Bo Bichette Can Return for Division Series
Lucas Giolito

Won't be on Wild-Card Roster With Elbow Issue
Alex Bregman

Should be Good for Game 1 of Wild-Card Series
Chase Elliott

Steals the Win at Kansas and Locks Into the Round of 8
Chase Briscoe

Earns Another Top-Five Finish at Kansas
Christopher Bell

Finishes Third at Kansas Speedway on Sunday
Kyle Larson

Strong Kansas Performance Positions Him to Advance in the 2025 Playoffs
Joey Logano

Kansas Struggles End In Disappointment
Dominick Reyes

Suffers First-Round Knockout Loss
Carlos Ulberg

Gets First-Round Knockout
Ivan Erslan

Loses Third Fight in a Row
Ramon Taveras

Drops Decision At UFC Perth
Jack Jenkins

Gets Back In The Win Column
Jake Matthews

Suffers Third-Round Submission Loss
Neil Magny

Pulls Off Comeback Win
Charlie Campbell

Suffers First-Round Submission Loss
Tom Nolan

Gets First-Round Submission Win
Denny Hamlin

Despite Power-Steering Failure, Denny Hamlin Dominates and Finishes Second at Kansas
NASCAR

Bubba Wallace's Playoff Bid Likely Ends After Scrape With Boss at Kansas
William Byron

Runs Poorly, Still Finishes in the Top 10
Tyler Reddick

Finishes Seventh at Kansas Despite Distractions
Shane Van Gisbergen

Earns First Cup Series Top-10 Finish on an Oval
Pete Alonso

to Opt Out of Contract and Enter Free Agency
Clayton Kershaw

Not Available for Wild-Card Series
Noah Gragson

May Be A Sneaky DFS Option For Kansas Lineups
Todd Gilliland

Is A Quality Value Option for Kansas Lineups
Kyle Larson

the Favorite to Win at Kansas
Ryan Blaney

the Chalk DFS Play at Kansas
Denny Hamlin

Has Struggled at 1.5-Mile Tracks This Season
William Byron

a Solid DFS Pivot at Kansas
Alex Bowman

Will Alex Bowman's Top-10 Streak at Kansas Continue?
Ryan Preece

Should Have Speed at Kansas
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