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Sep 18, 2026, 5:25 PM ET

San Francisco 49ers rookie running back Kaelon Black (groin) is listed as questionable to play in the team's Week 2 contest on Sunday against the Miami Dolphins, according to Matt Maiocco of NBC Sports. Black popped up on the team's injury report on Thursday and was listed as limited, the first sign that he might be in danger of missing this weekend's home opener. The 24-year-old third-rounder from Indiana has become the handcuff option for fantasy managers who have Christian McCaffrey rostered after he was impressive with 14 carries for 65 yards in the season-opening win over the division-rival Los Angeles Rams in Australia last week. If Black is unavailable to play in what would be his second NFL game, Jordan James would see a much bigger role as the change-of-pace option behind CMC, who the 49ers might be looking to monitor in terms of his workload all season long.--Keith Hernandez
Source: NBC Sports - Matt Maiocco

Sep 18, 2026, 5:24 PM ET

Las Vegas Raiders quarterback Kirk Cousins will be challenged to keep the winning momentum going as he faces a sturdy Los Angeles Chargers defense in Week 2. The veteran play caller was solid in his debut with the Silver and Black, completing 21 of 30 passes for 160 yards with three touchdowns in a 27-13 win against the Miami Dolphins, though he also threw two interceptions. The Chargers allowed 277 passing yards in a Week 1 loss to the Arizona Cardinals, but ranked fifth in the league in 2025 with just 179.9 passing yards allowed per game. Cousins got away with making a lot of short passes to running back Ashton Jeanty against Miami, but will need to utilize Vegas' young receiving corps to succeed on the road against the Bolts. The four-time Pro Bowl selection remains too risky to start in standard redraft leagues but has deep-league fantasy potential, and a strong performance against a good Chargers defense could raise his value.--Chelena Goldman
Source: ESPN

Sep 18, 2026, 5:22 PM ET

When asked about getting wide receiver Jaylen Waddle more involved after his quiet debut with the team in the Week 1 season-opening loss to the division-rival Kansas City Chiefs on Monday night, Denver Broncos head coach Sean Payton said, "Our intentions a week ago were that. And so we just gotta be more deliberate, maybe, and yet, without forcing it. But he's going to have his touches." The 27-year-old was one of the biggest busts of the week for fantasy football managers, as he caught just one of his three targets for two yards on a night in which the Broncos' offense just looked out of sorts aside from one touchdown drive. Waddle had a key third-down drop on one of his three targets, and he did not seem to gel with quarterback Bo Nix. That was not the sentiment at all during training camp, so fantasy managers should hope for Payton and offensive coordinator Davis Webb to grease Waddle's squeaky wheel in a Week 2 home matchup against the Jacksonville Jaguars. After his quiet Week 1 performance, Waddle could quickly bounce back for fantasy managers as a WR2.--Keith Hernandez
Source: The Athletic - Nick Kosmider

Sep 18, 2026, 5:21 PM ET

The Kansas City Chiefs defense will take on the Indianapolis Colts on Sunday night in Week 2. The Chiefs defense played a remarkable game in Week 1, holding the Denver Broncos offense to just 10 points while sacking Bo Nix four times and intercepting him once. Despite the positive vibes around this squad following that performance, there are some negatives to discuss heading into Sunday. The Kansas City unit is dealing with injuries to some of their key players. Chris Jones and Mansoor Delane are listed as questionable, and Chamarri Conner has already been ruled out. These players are a big part of the Chiefs' defensive game plan, and their absence downgrades the strength of this unit. That said, the Chiefs offense will likely do their part to take some pressure off the defense by slowing the pace of the game. With a more run-heavy approach on offense, Kansas City can extend drives and keep opposing offenses off the field. The Chiefs defense will have to contend with a Colts offense that scored 23 points against the Baltimore Ravens in Week 1, but the key to stopping them lies with Jonathan Taylor. It is no secret that Jonathan Taylor is the engine of the Colts offense, and with aging Keenan Allen and Alec Pierce still working his way back from injury, the Chiefs defense can win by stopping Taylor. This is easier said than done, but this unit did just hold the Broncos rushers to 61 yards on 15 rushes. The Chiefs defense is ranked 10th in our RotoBaller Week 2 rankings, making it a unit worthy of starting lineups this week.--Joshua Costello
Source: Chiefs.com

Sep 18, 2026, 5:19 PM ET

Las Vegas Raiders running back Ashton Jeanty is set for another huge week as the Silver and Black travel to Los Angeles to face the Chargers. The former Heisman Trophy finalist has been nursing an ankle injury but hasn't missed any practice or game time. The ailment clearly hasn't hindered his game, as Jeanty logged 23 carries for 102 rushing yards and added six receptions for 45 yards and two receiving touchdowns against the Miami Dolphins in Week 1. The Raiders haven't defeated the Chargers since 2023 and haven't won at SoFi Stadium since 2020, and Jeanty's well-rounded play will have to be top-notch against an LA rush defense that allowed just 116 yards in Week 1. The second-year back is an RB1 across fantasy formats, even against a tough opponent like LA, as the Raiders aim to start the season 2-0.--Chelena Goldman
Source: ESPN

Sep 18, 2026, 5:15 PM ET

Kansas City Chiefs tight end Travis Kelce caught three passes for 71 yards in the 31-10 victory over the Denver Broncos in Week 1. Most of those yards came on the back of one big play that went for 59 yards. The veteran tight end caught the ball in the middle of the field with blockers ahead of him and he was off to the races. Despite the long catch-and-run, Kelce was unable to find the end zone. While he did lead the team in receptions and receiving yards, the passing volume for Kansas City was low due to the excellent performance of running back Kenneth Walker. Walker and the run game carried the offense and the pass catchers did not have to do much in the blowout win. If this is the recipe for Chiefs success moving forward, Kelce will have to score touchdowns to be considered a viable fantasy option. It could happen against the Indianapolis Colts in Week 2, since the Colts defense just surrendered 41 points to the Baltimore Ravens in Week 1. Kelce is ranked TE11 in our RotoBaller Week 2 PPR rankings, making him a low-end TE1 option this week.--Joshua Costello
Source: NFL - Twitter

Sep 18, 2026, 5:15 PM ET

Los Angeles Rams wide receiver Puka Nacua (undisclosed) is not practicing on Friday afternoon, according to Benjamin Royer of The Orange County Register. It is unclear why Nacua is not practicing in the team's second practice of the week as they prepare to take on the New York Giants in Week 2 on Monday night. Fantasy managers will want to check back on Friday to see the official reasoning for Nacua's absence, but they will be keeping their fingers crossed that it is nothing serious. The 25-year-old did not appear to get injured at all in the Week 1 season-opening loss to the division-rival San Francisco 49ers last Thursday in Australia, when he put up five receptions on nine targets for 74 yards and no touchdowns. The former fifth-rounder from BYU is a must-start in all fantasy leagues when he is healthy, but if his reason for missing practice on Friday is serious enough to keep him out in Week 2, Davante Adams would be the new WR1 for the Rams in a perfect bounce-back spot after his quiet season opener.--Keith Hernandez
Source: The Orange County Register - Benjamin Royer

Sep 18, 2026, 5:12 PM ET

Kansas City Chiefs wide receiver Xavier Worthy will face the Indianapolis Colts on Sunday night in Week 2. Worthy, like fellow receiver Rashee Rice, had a down game as the Chiefs offense was centered around running back Kenneth Walker. Walker exploded for 191 total yards, leaving Worthy with just three catches for 18 yards. The encouraging news is that Worthy was tied with Walker for the most targets on the team in Week 1, so maybe the second-year wideout can convert those opportunities into big plays against the Colts. The Colts defense was just trounced by the Baltimore Ravens to the tune of 41 points in Week 1. If Kansas City can marry the pass game with the run game in Week 2, Worthy may be able to make some things happen as the defense is focused on stopping Walker. Worthy is ranked WR54 in our RotoBaller Week 2 PPR rankings, making him a deep league WR3 option with a low floor heading into Sunday.--Joshua Costello
Source: ESPN.com

Sep 18, 2026, 5:03 PM ET

Indianapolis Colts wide receiver Alec Pierce (heel) practiced in full on Friday and will not carry an injury designation into his team's Week 2 matchup against the Kansas City Chiefs. The 26-year-old was held out of practice on Thursday due to a heel issue, but it appears the injury is not serious enough to keep him off the field on Sunday. In the Colts' Week 1 loss to the Baltimore Ravens, Pierce recorded four catches for 61 yards on six targets. The talented wideout is expected to play a larger role in his team's offense in 2026. However, Indianapolis has other capable target-earners in wide receivers Josh Downs and Keenan Allen, as well as tight end Tyler Warren. The Colts also face a tough matchup against the Chiefs defense, which dominated the Denver Broncos' passing game in Week 1. All in all, Pierce profiles as a borderline flex option for fantasy managers in Week 2.--Will Brady
Source: Indianapolis Colts

Sep 18, 2026, 4:59 PM ET

Kansas City Chiefs wide receiver Rashee Rice was listed on the injury report with the knee injury that he's been rehabbing since last season, but had no issues practicing fully all week and is no longer listed on the report heading into the weekend. Rice had a disappointing Week 1 performance in the win over the Denver Broncos. Rice had just two catches for 19 yards and a touchdown in last week's contest. The touchdown came on a bit of a broken play where two Broncos defenders missed their tackles and Rice had a free run to the end zone. It was encouraging to see the wideout score, but his usage in the passing game was underwhelming. Kansas City leaned on running back Kenneth Walker heavily, and it paid off big time as the Chiefs ended up winning by 21 points. While the identity of the offense may have shifted to run-heavy, quarterback Patrick Mahomes will still need to pass the ball to keep defenses honest, and Rice should be the primary target. Rice will look to get things right this Sunday night against the Indianapolis Colts. The Colts defense looked lost as the Baltimore Ravens scored 41 points on them in Week 1. The Chiefs offense should be capable of putting up similar production against a beatable defensive unit. Rice is ranked WR23 in our RotoBaller Week 2 PPR rankings, making him a low-end WR2 heading into this week's matchup.--Joshua Costello
Source: Chiefs.com

Sep 18, 2026, 4:59 PM ET

Minnesota Vikings quarterback Carson Wentz is a playable option with a favorable matchup Sunday at Chicago now that Minnesota has ruled out starter Kyler Murray (concussion) from returning in Week 2. The veteran backup played well in relief last week against Green Bay, recovering from a few poor throws early to connect on three touchdowns as the Vikings rallied to beat Green Bay. Now, Wentz will face a Bears defense that ranks 29th in air yards allowed and surrendered 156 yards after the catch last week. The journeyman naturally comes with the risk of turnovers and the inability to avoid sacks that have plagued him most of his career, but he's still facing a shaky defense and throwing to a corps of pass catchers led by receiver Justin Jefferson. As one of RotoBaller's top 24 QB options this week, Wentz is startable in formats that play more than one quarterback.--Nick Piotrowicz
Source: RotoBaller

Sep 18, 2026, 4:56 PM ET

Kansas City Chiefs rookie running back Emmett Johnson displayed his elusiveness and pass-catching ability in Week 1. Johnson rushed eight times for 24 yards and caught two passes for 44 yards. Both of his catches led to explosive plays, one for 19 yards and the other for 25 yards. The rookie showed that the Chiefs really found something in the back out of Nebraska and his role may increase if he continues to impress. Johnson's next opportunity to show off will be against the Indianapolis Colts on Sunday night. The Colts just gave up 202 rushing yards to the Baltimore Ravens, so even if fellow back Kenneth Walker goes off there should still be enough chances for Johnson to perform. The 22-year-old's upside will be capped running behind Walker, but he should be more and more involved if he continues to do well with his limited touches. Johnson is ranked RB49 in our RotoBaller Week 2 PPR rankings, making him a desperation flex option in deep leagues. Johnson remains a better bench stash than an option to plug into lineups for Week 2.--Joshua Costello
Source: ESPN.com

Sep 18, 2026, 4:55 PM ET

Now that Minnesota Vikings running back Jordan Mason (finger) will miss at least four games on injured reserve, fellow running back Aaron Jones Sr. is a solid RB2 option as the Vikings prepare to play Chicago in Week 2. What certainly looked to be a backfield split that slightly favored Mason is now a backfield that features Jones, journeyman DeeJay Dallas, and rookie Demond Claiborne, who was inactive in Week 1. While Jones may not be a workhorse any longer, his fantasy prospects have certainly improved in time to face a shaky Bears defense that ranks 29th in yards per carry allowed, 29th in air yards allowed, and missed nine tackles last week. Even without starting quarterback Kyler Murray (concussion), Jones' receiving ability and control of the backfield are appealing. As RotoBaller's No. 20 running back this week, Jones should draw serious consideration in most formats against Chicago.--Nick Piotrowicz
Source: RotoBaller

Sep 18, 2026, 4:53 PM ET

Kansas City Chiefs running back Kenneth Walker was the heart and soul of the offense on Monday night in Week 1. Walker handled 23 carries for 173 yards and a touchdown as well as three catches for 18 yards and another score. The 25-year-old looked unstoppable facing one of the toughest defenses in the league, which bodes well for him continuing to have impressive performances this season. His 23 carries and six targets equated to 29 total opportunities in his Chiefs debut, which is gold for fantasy. Walker will look to stay as involved and efficient in Week 2 against the Indianapolis Colts. The Colts defense was just gashed by Baltimore Ravens running back Derrick Henry, who rushed 24 times for 144 yards and three touchdowns. Walker proved in Week 1 that he is capable of having ceiling performances like Henry, so the Colts defense might have to prepare for another rushing barrage this week. Walker looks like everything the Chiefs offense has been missing and it looks like they will rely on him to set the tone offensively. Walker is ranked RB4 in our RotoBaller Week 2 PPR rankings, making him a rock-solid RB1 option heading into Sunday night.--Joshua Costello
Source: ESPN.com

Sep 18, 2026, 4:50 PM ET

Cincinnati Bengals head coach Zac Taylor "made clear" that quarterback Joe Burrow (back) is "good to go" for the team's Week 2 matchup against the Houston Texans, per Paul Dehner Jr. of The Athletic. Burrow is officially listed as questionable to play, but it appears as though he will be on the field against Houston. In Cincinnati's Week 1 win over the Tampa Bay Buccaneers, the 29-year-old completed 25 of 35 pass attempts for 254 yards, one touchdown, and one interception. While he faces a difficult matchup on paper in Week 2 against the Texans' defense, Burrow is always a threat to provide high-end fantasy production as long as he's on the field. Assuming he's active, Burrow profiles as a low-end fantasy QB1 on Sunday.--Will Brady
Source: The Athletic - Paul Dehner Jr.

Sep 18, 2026, 4:48 PM ET

Kansas City Chiefs quarterback Patrick Mahomes was once again listed on the injury report with a knee injury, but was a full participant in every Kansas City practice heading into Week 2. This injury report listing will likely remain throughout the season as the Chiefs manage Mahomes ' return from his ACL injury. That said, he was practicing fully and should be considered ready to face the Indianapolis Colts on Sunday night. Mahomes had an encouraging season debut in the 31-10 win over the Denver Broncos. The Chiefs superstar completed 15 of 27 pass attempts (56%) for 184 yards and two touchdowns, but most encouraging was the fact that he scrambled for a 15-yard touchdown in the middle of the field. The fear surrounding Mahomes coming off the scary knee injury was that his mobility would suffer, but it appears he put those worries to rest. Mahomes should have an easier time passing the ball against a Colts defense that just allowed 41 points to the Baltimore Ravens in Week 1. Mahomes is ranked QB12 in our RotoBaller Week 2 rankings, making him a justifiable QB1 for fantasy managers.--Joshua Costello
Source: Chiefs.com

Sep 18, 2026, 4:46 PM ET

Mostly limited to deep sleeper consideration during the offseason, Minnesota Vikings running back Demond Claiborne could have an elevated role sooner than expected ahead of the Vikings' Week 2 trip to Chicago. The Minnesota backfield is in need of assistance now that Jordan Mason (thumb) will miss at least a month, vacating his rushing-first role and opening the door for the rookie to earn his first carries. Claiborne showed some pop in training camp, but he was inactive in Week 1 in favor of journeyman DeeJay Dallas. Aaron Jones Sr. will lead the Minnesota backfield, but at this stage of his career, he's unlikely to be an every-down workhorse again. It warrants mentioning that neither Jones nor Mason is currently under contract for next season, so Claiborne could change the team's plans if he capitalizes on his opportunities as a rookie. As RotoBaller's No. 58 running back this week, he might not be ready for starting lineups just yet, but forward-thinking managers might consider stashing him in case he breaks loose in Mason's absence.--Nick Piotrowicz
Source: RotoBaller

Sep 18, 2026, 4:44 PM ET

The Cincinnati Bengals defense looked like one of the most improved units in the league against the Tampa Bay Buccaneers in Week 1. The Cincinnati defensive unit swarmed quarterback Baker Mayfield and sacked him four times while also recovering four fumbles, one of which was returned for a touchdown. This Bengals defense was arguably the worst squad in 2025, but they no longer look like a pushover matchup. Cincinnati will try to keep this momentum heading into their matchup against the Texans in Houston. The Texans offense is hobbled heading into the weekend with wide receiver Nico Collins ruled out with a hamstring injury. With the focal point of the Texans' passing game out with injury, the Bengals defense can focus their attention on stopping David Montgomery in the run game. This defense is not without its own injuries, though, most notably defensive tackle B.J. Hill, who is listed as questionable. Still, the Bengals should be ready to take on a Texans offense that is far from 100%. The Bengals defense is ranked 15th in our RotoBaller Week 2 rankings, making them a middle-of-the-pack unit to consider for Sunday.--Joshua Costello
Source: Bengals.com

Sep 18, 2026, 4:42 PM ET

Wide receiver Justin Jefferson is once again a WR1 option as the Minnesota Vikings prepare to take on the struggling Chicago Bears defense. The superstar receiver's stat line last week (eight catches, 92 yards, and two touchdowns) didn't show any signs of struggle despite the Vikings playing the majority of the game without starting quarterback Kyler Murray (concussion). The Vikings already ruled out Murray this week in favor of backup Carson Wentz, with whom Jefferson connected for both of his touchdowns in the comeback victory against Green Bay. Now, however, the LSU alum faces a Bears defense that allowed 156 yards after the catch last week and ranks 29th in air yards allowed. With running back Jordan Mason (thumb) on injured reserve, Jefferson surely will be an integral part of the Minnesota game plan. He should be locked into lineups in all formats.--Nick Piotrowicz
Source: RotoBaller

Sep 18, 2026, 4:41 PM ET

Minnesota Vikings wide receiver Jordan Addison should be considered a volatile WR4 option in Week 2, albeit one facing an excellent matchup against the Chicago Bears. Despite the Vikings scoring 39 points in Week 1, the fourth-year receiver didn't record a catch on just two targets. The Vikings also will be starting backup quarterback Carson Wentz again, as Minnesota already ruled out starter Kyler Murray (concussion). The Bears' defense, however, ranks 29th in air yards allowed and surrendered 351 yards passing to Carolina last week. While Addison is always in fellow receiver Justin Jefferson's shadow, the circumstances suggest a few high-value targets could be coming Addison's way this week. Managers who played Addison in Week 1 can't be faulted for feeling like Charlie Brown lining up to kick the football again, but the matchup is favorable enough that Addison is at least worthy of consideration for a flex spot, especially in deeper formats.--Nick Piotrowicz
Source: RotoBaller