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Chargers Defense has a Tough Matchup in Potential Shootout

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Oct 17, 2025, 7:00 PM ET

The Los Angeles Chargers D/ST faces a tough challenge against the Indianapolis Colts, who have the league's top-scoring offense (32.3 PPG) and the most rushing touchdowns per game (2.2), led by fantasy RB1 Jonathan Taylor. Although the Chargers rank second in Opponent Red Zone Scoring (42.86%), their weakness against the run (28th in opponents' yards allowed per rush) creates a significant mismatch against the Colts' run-heavy approach. While the potential return of Khalil Mack (elbow), who was designated to return from IR this week, provides some boost for their pass rush, the likely game script of a high-scoring offensive battle hinders defensive points. RotoBaller has moved the D/ST down to D/ST22. It's better to consider other D/ST options this week.--Don Fanelli
Source: RotoBaller
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