TAP FOR 6 MONTHS OF PREMIUM FREE 💰
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

FanDuel NFL DFS Lineup Picks for Week 10 - Daily Fantasy Football Targets Include Patrick Mahomes, Tua Tagovailoa, Travis Etienne Jr., Saquon Barkley, Travis Kelce

Patrick Mahomes - Fantasy Football Rankings, DFS Lineup Picks, NFL Injury News

Dennis Clausen highlights the top FanDuel NFL DFS lineup picks for Week 10 of the 2022 season, and some value sleepers for your daily fantasy football rosters.

So how did everyone like Joe Mixon's performance last Sunday? For those who had him in their lineups, congratulations on your victory. For those who didn't, well, sorry about that. While most expected Mixon to have a breakout performance, few had predicted Justin Fields would do the same. Even Cole Kmet had himself a game, scoring two touchdowns against the Dolphins for his first career multi-score performance.

On the other hand, it wasn't all sunshine, rainbows, and butterflies in Week 9 for players like Josh Allen, who could not lift his team past the New York Jets. Even worse, he suffered an elbow injury. Jonathan Taylor also didn't have a good week, mainly because he didn't play due to his nagging ankle issue.

In this article, I will be providing you with my Week 10 daily fantasy football lineup picks for FanDuel. These lineups can vary from higher-priced players and elite options to lower-priced players and value picks on FanDuel. Be sure to also check out our weekly DraftKings DFS lineup picks and lots of other great NFL DFS articles and NFL DFS tools to help you win big! Also, feel free to give me a follow on Twitter @DennisMClausen. Let's get started!

Happy New Year! Save 30% on any Premium Pass using discount code NEW. Win more with our DFS, Betting and Season-Long Pass, get expert tools and advice from proven winners! GAIN ACCESS

 

FanDuel Quarterbacks - Week 10 DFS Lineup Picks

Patrick Mahomes - vs. JAC ($8,500)

There aren’t many reliable options at the quarterback spot in Week 10. Josh Allen has an elbow injury, so how much will he be limited if he can go? Despite Justin Fields' efficient Week 9 performance, is he a trustworthy DFS option?

With that said, Mahomes is a guy DFS managers can depend on. He’s thrown over 400 yards in each of his last two games. While he hasn’t been the most accurate thrower, he should continue to air the ball out enough to remain one of the best fantasy quarterbacks of the week. With the Jaguars on tap, Mahomes’ ceiling may be higher on Sunday than at any point during the year.

Tua Tagovailoa - vs. CLE ($8,100)

Tagovailoa has taken a beating this season, resulting in the signal-caller missing a few games. However, since returning in Week 7, he’s turned up the volume. He threw for 382 yards and three touchdowns against the Lions in Week 8.

Tagovailoa followed that by once again surpassing the 300-yard mark through the air versus Chicago on Sunday while adding another three passing touchdowns. While the weather is starting to worsen in many parts of the country, Miami has a beautiful forecast, which is always a plus. Nonetheless, the Browns’ defense may not be enough to keep Tagovailoa from having another spectacular fantasy showing.

Also Consider: Matthew Stafford ($6,700)

 

FanDuel Running Backs - Week 10 DFS Lineup Picks

Saquon Barkley - vs. HOU ($9,500)

Fresh of a bye, Barkley is back and ready to have some fun at Houston's expense. The former Nittany Lion has been on a roll and been one of the best fantasy options all year.

He's amassed a third-best 779 rushing yards and currently leads the NFL with 13 carries of at least 20 yards or more. There's not a team in the league worse than the Texans at defending the running back position, so Barkley should be a lock for DFS managers.

Travis Etienne Jr. - @ KC ($8,000)

Etienne has emerged as one of the top fantasy options going, even more so after James Robinson was traded to the Jets. The rookie is arguably coming off the best game of his young career by compiling 109 yards off 28 carries against the Raiders in Week 9. He also found the end zone twice in that one.

The rookie has now scored at least once in each of his last three games. While the Chiefs’ defense should prove more challenging, the unit has had its share of problems stopping the run.

Also Consider: Derrick Henry ($9,400), Josh Jacobs ($8,400), Jonathan Taylor ($7,000), Devin Singletary ($5,600)

 

FanDuel Wide Receivers - Week 10 DFS Lineup Picks

Cooper Kupp - vs. ARI ($9,200)

Despite Matthew Stafford’s subpar play in 2022-23, Kupp remains the best wide receiver in the NFL. He has had at least one touchdown in 50% of his appearances and currently sits second in the league with 93 targets.

Kupp has played well against the Cardinals over the years. In his nine encounters against Arizona, he’s totaled five touchdowns and has averaged just over 72 receiving yards per game. With the birds banged up on the defensive end, Kupp should remain an elite option for DFS enthusiasts.

Tyreek Hill - vs. CLE ($9,000)

Hill is firing on all cylinders with Tua Tagovailoa back in the lineup. He’s the first receiver to surpass the 1,000-yard mark and is comfortably leading the league with 765 air yards.

With a seemingly healthy signal-caller, Hill should continue to produce. He has combined for 49 fantasy points while amassing 19 catches for 331 yards and a touchdown in the last two weeks, so there is no doubt about it, get him in the lineup.

Also Consider: Jaylen Waddle ($8,200), Amon-Ra St. Brown ($6,900), Zay Jones ($5,500)

 

FanDuel Tight Ends - Week 10 DFS Lineup Picks

Travis Kelce - vs. JAC ($8,500)

If you thought kickers were depressing, tight ends haven’t been better in 2022-23. Taysom Hill, for example, is the second costliest option on the slate at the position. However, he had just one carry and one Target on Monday night against Baltimore. In addition, the ailing Mark Andrews is on a bye, and Zach Ertz is due for his usual disappearing act.

On the other hand, Kelce has been as efficient as it can get. Sure he hasn’t scored in three weeks. Yet, the veteran hasn’t seen less than seven targets from Patrick Mahomes in any game this season. For those who are sick and tired of taking the constant gamble, Kelce’s got your back.

Also Consider: T.J. Hockenson ($6,00)



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy football app for iPhone and Android with 24x7 player news, injury alerts, rankings, starts/sits & more. All free!

More Weekly DFS Analysis

POPULAR FANTASY TOOLS

Expert Advice
Import Your Leagues
Weekly Rankings
Compare Any Players
Projections
Articles & Tools
Weekly Planner
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Luis Arraez

Signs One-Year Deal With Giants
Troy Terry

Ready to Return Sunday
Victor Hedman

Set to Return Sunday
Connor McMichael

Out Week-to-Week
Kris Letang

Out for Four Weeks
Nico Hischier

a Game-Time Call Saturday
Jack Hughes

Won't Play Saturday
Linus Ullmark

Returns to Action Saturday
Blake Snell

Dodgers Plan to Have Blake Snell Ready for Opening Day
Paul George

Suspended for 25 Games
Shohei Ohtani

Will be Ready to Pitch to Start the 2026 Season
Francisco Lindor

Won't Play in WBC After Elbow Surgery
Nikola Vučević

Nikola Vucevic Unlikely to Play Against Miami
Tre Jones

Still Sidelined as Bulls Face Miami
Tyler Herro

Remains Sidelined Saturday vs. Bulls
Norman Powell

Ruled Out vs. Bulls
Jeremy Sochan

Still Sidelined as Spurs Visit Charlotte
Keyonte George

Injures Ankle Late in Loss to Nets
Stephen Curry

Exits Early Against Pistons with Knee Issue
Charlie Coyle

Pots Second Career Hat Trick
Filip Hronek

Expected to Play Saturday
Pavel Zacha

Not Traveling With Bruins
Elias Lindholm

to Miss at Least Two More Games
William Nylander

on Track to Return Saturday
Kris Letang

Misses Practice, Uncertain for Saturday
Evgeni Malkin

Iffy for Saturday
Cade Cunningham

Ready to Rock Friday
Gui Santos

Available Against Pistons
Caris LeVert

Remains Sidelined Friday
Craig Porter Jr.

Out Against Suns
Jonas Valančiūnas

Jonas Valanciunas Active Friday
Jamal Murray

Upgraded to Available Friday
Nikola Jokić

Nikola Jokic Officially Available Friday
Vinnie Pasquantino

Royals Agree on Two-Year Contract
Neemias Queta

Back in Action Friday
Miles McBride

Misses Friday's Game
Josh Hart

Active Against Trail Blazers
Tre Johnson

Out Against Lakers
Khris Middleton

Sits Out Meeting With Lakers
Austin Reaves

Remains Out Friday
Jacob Wilson

Signs Seven-Year Extension
Diego Lopes

An Underdog At UFC 325
Alexander Volkanovski

Set For UFC 325 Main Event
Benoît Saint Denis

Benoit Saint Denis Looks To Extend His Win Streak
Dan Hooker

Set For UFC 325 Co-Main Event
Mauricio Ruffy

Looks To Get Back In The Win Column
Rafael Fiziev

Returns At UFC 325
CFB

Texas Lands Wake Forest Transfer Sterling Berkhalter
Samuel Ersson

Sustains Lower-Body Injury Thursday
Pavel Zacha

Exits Early Thursday
Charlie Lindgren

Hurt Versus Red Wings
Jack Hughes

Exits With Lower-Body Injury Thursday
Brad Marchand

Suffers New Injury Blow
Patrick Kane

Becomes NHL's Highest-Scoring U.S-Born Player
Ukko-Pekka Luukkonen

Expected to Miss a Week
Tommy Edman

Will Have Delayed Start to Spring Training, Could Miss Opening Day
Kirk Cousins

Falcons Expected to Release Kirk Cousins
Chase Brown

Working on Extension With Bengals
Michael Penix Jr.

Hopes to be Ready for Week 1
Isaac Paredes

Not a Lock for Opening Day Lineup?
Dalton Kincaid

Doesn't Need Offseason Surgery
Josh Allen

Undergoes Foot Surgery
Josh Allen

on Crutches, Wearing Walking Boot
Corbin Carroll

a Top Fantasy Outfielder After Joining 30-30 Club
Jonah Tong

Won't Pitch in the World Baseball Classic
CFB

Michigan RB Bryson Kuzdzal Withdrawing from Transfer Portal
Aaron Judge

Appears to be Past his Elbow Issues
Bo Nix

Expected to Resume Training in 4-6 Weeks
Michael Penix Jr.

Thinks he'll be Ready by April
Evan Carter

Establishes a Goal to Steal 30 Bases
Edouard Julien

Traded to the Rockies
Cleveland Browns

Browns Hiring Todd Monken as Next Head Coach
Sahith Theegala

Off to Much Better 2026 Start
Gary Woodland

an Intriguing Option at Torrey Pines This Week
CJ Abrams

Giants Offer "Aggressive Pitch" for CJ Abrams
Andrew Putnam

Hopes to Keep Momentum Rolling This Week
Matthieu Pavon

Seeks to Return to 2024 Form at Torrey Pines
Luke List

Still Looking For Birdies at Torrey Pines
Jake Knapp

Faces Stiff Challenge at Farmers Insurance Open
Rasmus Hojgaard

Needs to Play Better at Torrey Pines
Christiaan Bezuidenhout

Could Struggle at Farmers Insurance Open
J.J. Spaun

A Steady Option At Farmers Insurance Open
Andrew Novak

Looking For More Success At Torrey Pines
Denny McCarthy

A Wild Card At Farmers Insurance Open
Max Homa

Looks To Keep Resurgence Going At Torrey Pines
Joe Highsmith

Struggling Heading Into Torrey Pines
Wyndham Clark

Looks To Carry Momentum Into Farmers Insurance Open
Tony Finau

Aims To Turn Things Around At Torrey Pines
Akshay Bhatia

Looks to Bounce Back at Torrey Pines
Paul Goldschmidt

Yankees Expressing Interest in Re-Signing Paul Goldschmidt
Bo Bichette

Won't Play in World Baseball Classic
NFL

Bill Belichick Won't be First-Ballot Hall of Famer
Carlos Correa

Won't Play for Puerto Rico in World Baseball Classic
Si Woo Kim

Looks to Continue Incredible Run at Torrey Pines
Jason Day

has a Good Chance to Keep Momentum This Weekend
Keegan Bradley

has Good Course History at Torrey Pines
Billy Horschel

Isn't a Great DFS Option at Torrey Pines
Aaron Rodgers

Mike McCarthy Says he Wants Aaron Rodgers to Return
Will Zalatoris

Has a Shot to Challenge at the Farmers Insurance Open
Drake Maye

Expected to be Fine for Super Bowl
Tennessee Titans

Titans Set to Hire Brian Daboll as New Offensive Coordinator
Buffalo Bills

Bills Promote Joe Brady to Head Coach
CFB

Quarterback Brayden Fowler-Nicolosi Signs with Michigan
CFB

Darian Mensah Reaches Settlement with Duke, Expected to Land at Miami
Eugenio Suárez

Eugenio Suarez Not Drawing Interest on Open Market?
Shedeur Sanders

Named as Pro Bowl Replacement
Framber Valdez

Among Many High-End Pitchers on Free-Agent Market
Jose Altuve

Won't Participate in World Baseball Classic
Harrison Bader

Agrees With Giants on Two-Year Deal
Paddy Pimblett

Drops Decision
Justin Gaethje

Becomes the New Interim-Lightweight Champion
Song Yadong

Suffers Unanimous Decision Loss
MMA

Sean O'Malley Gets Back In The Win Column
Waldo Cortes-Acosta

Extends His Win Streak
Derrick Lewis

Suffers Second-Round TKO Loss
Los Angeles Chargers

Chargers Officially Hire Mike McDaniel as Offensive Coordinator
Jaxon Smith-Njigba

Dominates in NFC Championship Game Win

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP