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Oct 16, 2026, 7:00 PM ET

San Francisco 49ers wide receiver Deebo Samuel Sr. (hamstring) missed a second straight practice on Friday, according to Harrison Rich of The San Francisco Chronicle. Although the 49ers do not plan to place Samuel on Injured Reserve at this time following his hamstring injury on Sunday in the Week 5 win over the division-rival Seattle Seahawks, the 30-year-old veteran is expected to miss several weeks, including Monday night's clash against the Washington Commanders in Week 6. Fantasy managers should not realistically expect him to make a return until their Week 9 game against the Las Vegas Raiders on Nov. 8 after their bye in Week 8. San Francisco is running out of healthy bodies at the receiver position, with veteran Mike Evans (ribs, Achilles) also hobbled and not practicing yet this week. It is possible that Christian Kirk (calf) makes his return from Injured Reserve this weekend to give the team some reinforcements. Samuel was seeing increased usage in 2026 in his return to the Niners given all their injuries and had 16 catches on 20 targets for 206 yards and three touchdowns before his hamstring injury on Sunday.--Keith Hernandez
Source: The San Francisco Chronicle - Harrison Rich
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Oct 16, 2026, 6:53 PM ET

San Francisco 49ers wide receiver Christian Kirk (calf) was listed as a limited participant in Friday's practice, according to The San Francisco Chronicle's Harrison Rich. It was originally believed that it was unlikely that Kirk would have his 21-day practice window opened to return from Injured Reserve this week, but the 29-year-old veteran returned to the field on Thursday and is now an option to make his 2026 season debut on Monday night against the visiting Washington Commanders. The 49ers' receiving corps is among the most banged up in the league, and the team is expected to be without veteran Deebo Samuel Sr. (hamstring) for multiple weeks after he was injured in the Week 5 win over the division-rival Seattle Seahawks. Veteran Mike Evans (ribs, Achilles) continues to play through injuries, but he has not practiced yet this week. Kirk may not return in Week 6, but he is a sneaky waiver-wire pickup in deeper fantasy leagues for those looking for WR depth. When he returns, Kirk has a clear path to WR2 duties in the Bay Area with everyone else literally injured.--Keith Hernandez
Source: The San Francisco Chronicle - Harrison Rich
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Oct 16, 2026, 6:44 PM ET

San Francisco 49ers wide receiver Mike Evans (ribs, Achilles) was listed as a non-participant for the second straight day on Friday, according to Harrison Rich of The San Francisco Chronicle. Evans is trending towards being at least questionable for Monday night's contest at home against the Washington Commanders, even if he returns to the practice field for the final session of the week on Saturday. The 33-year-old has been playing through a painful rib injury and is also now dealing with soreness in his Achilles. The 49ers cannot afford to have their best pass-catcher join the list of wideouts on Injured Reserve this year, which is why he has not been practicing much during the week. If Evans returns to practice on Saturday, he could have a good chance of playing in Week 6. The future Hall of Fame receiver will have an even higher target share if he is active on Monday night, with Deebo Samuel Sr. (hamstring) expected to miss time with a hamstring injury he suffered in the Week 5 win over the division-rival Seattle Seahawks. Despite battling nagging injuries in his first year in San Fran, Evans has secured 24 of his 34 targets for 326 yards and three touchdowns and has continued to be a must-start WR2 in fantasy.--Keith Hernandez
Source: The San Francisco Chronicle - Harrison Rich
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Oct 15, 2026, 5:47 PM ET

San Francisco 49ers veteran wide receiver Deebo Samuel Sr. (hamstring) was not seen in the portion of practice open to the media on Thursday, according to Nick Wagoner of ESPN. Samuel suffered a hamstring injury in the Week 5 win over the division-rival Seattle Seahawks that is expected to sideline him for multiple weeks, so it should not come as a big surprise that he is not practicing on Thursday. The good news for the 30-year-old pass-catcher is that head coach Kyle Shanahan said that the team will hold off on placing Samuel on Injured Reserve due to the team's bye in Week 8. Going on IR would have sidelined him for at least four games. With that said, fantasy managers should still be expecting Samuel to miss several games, so he might not be available again for the 49ers until Week 9. San Francisco's receiving corps is the most banged-up unit around the league, with veteran Mike Evans (Achilles, ribs) holding down the fort while battling through multiple injuries. With Samuel set to miss the Week 6 contest on Monday night against the Washington Commanders, veteran Brandin Cooks and Jacob Cowing will be much more involved, as well as tight end George Kittle.--Keith Hernandez
Source: ESPN.com - Nick Wagoner
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Oct 15, 2026, 4:11 PM ET

San Francisco 49ers head coach Kyle Shanahan said that wide receiver Mike Evans (Achilles, ribs) will not practice on Thursday due to Achilles soreness, per ESPN's Nick Wagoner. Evans has also been playing through a rib issue. The 33-year-old has been highly productive so far in 2026, recording 24 catches for 326 yards and three touchdowns on 34 targets across five games. However, Evans is now battling multiple ailments that could put his availability for San Francisco's Week 6 matchup against the Washington Commanders on Monday Night Football in question. The 49ers lost WR2 Deebo Samuel Sr. (hamstring) to a hamstring injury in Week 5, so the team could be without its top two wideouts in Week 6. If Evans is inactive, 49ers wide receivers Jacob Cowing, Brandin Cooks, and Jordan Watkins could all see increased workloads.--Will Brady
Source: ESPN - Nick Wagoner
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Oct 15, 2026, 3:37 PM ET

San Francisco 49ers wide receiver Christian Kirk (calf) had his 21-day practice window opened Thursday, according to Matt Maiocco of NBC Sports Bay Area, moving him closer to making his debut with the team. Kirk has been on injured reserve since the start of the season after straining his calf during training camp in July. Head coach Kyle Shanahan indicated earlier this week that Kirk was unlikely to resume practicing, making Thursday's development an encouraging sign. The 29-year-old caught 28 passes for 239 yards and one touchdown in 13 games with Houston last season, then added 10 receptions for 164 yards and two scores during the playoffs. His potential return comes at a welcome time for San Francisco, which expects Deebo Samuel Sr. (hamstring) to miss multiple games and still has Ricky Pearsall (knee) on injured reserve. Mike Evans remains the team's top receiving option, while Brandin Cooks is expected to handle additional work during Samuel's absence. Kirk could eventually factor into the receiving rotation, but he still needs to be activated from injured reserve. His availability for Monday's Week 6 matchup against Washington remains uncertain, making him a speculative fantasy option for now.--Bruno Mulé
Source: Matt Maiocco
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Oct 15, 2026, 12:45 PM ET

San Francisco 49ers veteran wide receiver Mike Evans seems to be the last man standing in the team's banged-up receiving corps, although the 33-year-old has not been immune to injuries himself. Battling through a painful rib injury over the last couple of weeks, Evans had his best game with the 49ers in the Week 5 win over the division-rival Seattle Seahawks, catching seven of his 10 targets for 113 yards and a touchdown. The future Hall of Famer also caught a successful two-point conversion in the big divisional victory. Through his first five games in San Francisco in 2026, Evans ranks as the WR24 in half-PPR leagues with 24 catches on 34 targets for 326 yards and three touchdowns. Injuries and durability could be an issue for the aging veteran down the stretch, but with the team's WR ranks decimated by injuries, Evans should continue to have a relatively high fantasy floor. He will have WR1 upside going into a Monday night matchup in Week 6 against a Washington Commanders defense that has allowed the fourth-most passing yards per game (255).--Keith Hernandez
Source: Pro Football Reference
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Oct 14, 2026, 9:13 PM ET

According to Bleacher Report, four men have been arrested in connection with the shooting of San Francisco 49ers defensive lineman Keion White in February. The shooting happened around 4 a.m. on Feb. 9 in a nightclub where White was hosting a private Super Bowl party. White was shot in the ankle and was taken to a hospital to undergo surgery. The men were booked into San Francisco County Jail on Monday and scheduled to appear in court on Wednesday. White has since returned to the field and recorded nine tackles and three sacks across the first five games of the season.--Andy Webb
Source: Bleacher Report
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Oct 13, 2026, 12:15 PM ET

San Francisco 49ers veteran wide receiver Deebo Samuel Sr. (hamstring) suffered a significant hamstring strain in the third quarter of Sunday's Week 5 win over the division-rival Seattle Seahawks and will miss "some time." It points to a bigger role for veteran Brandin Cooks, who played almost every snap after Samuel left, according to Matt Barrows of The Athletic. The 33-year-old Cooks caught one of his two targets for a seven-yard touchdown after not catching his only target in the Week 4 win over the Denver Broncos in his debut with the 49ers. Ricky Pearsall (knee) is out for the season, and De'Zhaun Stribling (ankle), Demarcus Robinson (ankle), and Christian Kirk (calf) all remain on Injured Reserve, so the 49ers' receiving corps is among the most banged-up units around the league. Veteran Mike Evans continues to battle injuries as well, so Cooks should become a much bigger part of the team's passing attack now that Samuel will also miss a couple of weeks. Cooks has six career 1,000-yard receiving seasons and caught 24 passes for 279 yards and no touchdowns in 15 games last year with the New Orleans Saints and Buffalo Bills. He is not currently rostered in any Yahoo leagues, but Cooks is worth a look for WR depth in deeper formats, with his role set to grow, starting in Week 6 on Monday night versus the Washington Commanders.--Keith Hernandez
Source: The Athletic - Matt Barrows
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Oct 13, 2026, 11:44 AM ET

San Francisco 49ers wide receiver Christian Kirk (calf) has yet to make his 2026 debut, and his continued absence is becoming particularly frustrating given the team's mounting injuries at the position. Head coach Kyle Shanahan indicated Monday that Kirk is unlikely to return to practice this week after suffering a calf injury during training camp. Deebo Samuel Sr. (hamstring) is expected to miss multiple weeks, Ricky Pearsall (knee) is out for the season, and both Demarcus Robinson (ankle) and De'Zhaun Stribling (ankle) remain on injured reserve. The depleted receiving corps could eventually provide Kirk with a meaningful opportunity, although Mike Evans remains San Francisco's primary receiving option. Kirk also struggled to make an impact with Houston in 2025, catching just 28 passes for 239 yards and one touchdown across 13 games. There is no established timetable for his return, and the 49ers have a Week 8 bye approaching. Kirk is worth considering for an available injured-reserve spot in deeper PPR leagues, but managers without that flexibility have little reason to prioritize him over healthy waiver-wire options.--Bruno Mulé
Source: RotoBaller
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Oct 12, 2026, 3:43 PM ET

San Francisco 49ers head coach Kyle Shanahan said on Monday that wide receiver Deebo Samuel Sr. (hamstring) is "going to miss" a couple of weeks with the strained hamstring that he suffered in Sunday's Week 5 win over the division-rival Seattle Seahawks, according to David Lombardi of The San Francisco Standard. Fantasy managers should expect Samuel to miss the next two games against the Washington Commanders and Atlanta Falcons. San Francisco then has their bye in Week 8, so the earliest that Samuel might return could be Nov. 8 at home against the Las Vegas Raiders. It is yet another injury to a key receiver for the 49ers, leaving veterans Mike Evans and Brandin Cooks, who both scored touchdowns on Sunday, and Jacob Cowing as the 49ers' starting receivers going into a Week 6 matchup next Monday night against Washington. The 30-year-old Samuel caught just two passes for 21 yards and carried the ball two times for four yards in Week 5 before leaving in the third quarter and never returning. Samuel has taken on a big role so far in 2025 in his return to the Niners, with their receiving corps so banged up, and he has produced a nice 16-206-3 line for his fantasy managers.--Keith Hernandez
Source: The San Francisco Standard - David Lombardi
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Oct 12, 2026, 9:59 AM ET

San Francisco 49ers wide receiver Deebo Samuel Sr. (hamstring) is scheduled to undergo an MRI to determine the severity of his injury. Samuel suffered a hamstring injury on a play that resulted in a fumble and was ruled out shortly after he went down. 49ers head coach Kyle Shanahan did not provide an update on the injury's severity in the post-game press conference but said, "I'll probably have one for you guys tomorrow, but I don't think he's coming back this week." In five games, Samuel has 16 catches for 206 yards and three touchdowns, plus 78 yards on the ground. If he misses time, Jacob Cowing and Brandin Cooks should help fill in, but the stars Mike Evans, George Kittle, and Christian McCaffrey will see upticks in usage as well. Fantasy managers should monitor this situation, as Samuel seems likely to miss time with his hamstring injury.--Nathan Harvey
Source: Ian Rapoport - NFL Network
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Oct 12, 2026, 12:40 AM ET

San Francisco 49ers wide receiver Christian Kirk (calf) will likely remain on injured reserve even after he's eligible to be activated in Week 6, according to Nick Wagoner of ESPN.com. Following Sunday's win over the Seattle Seahawks, head coach Kyle Shanahan told Wagoner that he hasn't officially decided whether Kirk will be activated next week, but the answer would be no right now. That's not exactly the news that 49ers fans wanted to hear, as their team's wide receiver room has been absolutely decimated by injuries. In addition to Kirk, the 49ers are without De'Zhaun Stribling (ankle), Ricky Pearsall (right knee), and Deebo Samuel Sr. (hamstring). Pearsall is on season-ending IR, but assuming the other three players don't suit up in Week 6, we can expect Jacob Cowing and Brandin Cooks to occupy complementary roles behind Mike Evans.--Andersen Pickard
Source: RotoBaller
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Oct 11, 2026, 9:58 PM ET

San Francisco 49ers wide receiver Mike Evans (ribs) helped lift his team to a 32-29 win over the rival Seattle Seahawks. In a vintage performance, the 33-year-old Evans recorded season highs in receptions (seven) and receiving yards (113), while scoring a touchdown. Evans led the 49ers in all receiving categories. Evans is dealing with an injury to his ribs and did not practice on Thursday, while logging two limited sessions during the week. He was able to play 38 snaps against the Seahawks and was not slowed down by his injury in any way. Evans leads the 49ers in receptions with 24 and receiving yards with 326 in 2026. He has also scored three touchdowns. Evans continues to be a must-start player in a San Francisco wide receiver room that is dealing with multiple injuries.--Ryan O'Bleness
Source: RotoBaller
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Oct 11, 2026, 7:00 PM ET

San Francisco 49ers wide receiver Deebo Samuel Sr. (hamstring) has been ruled out for the rest of Sunday's game against the Seattle Seahawks, according to John Dickinson. Samuel looked to be in bad shape when he gingerly limped across the field during the third quarter. He was quickly ruled out for the rest of this game, and we'll see if he's able to suit up against the Washington Commanders next week. He'll finish his day, hauling in two receptions for 21 yards, while rushing the ball twice for an additional four yards on the ground. Mike Evans, Jacob Cowing, and George Kittle will be the primary pass-catchers for the rest of this game.--Andy Webb
Source: John Dickinson
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