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San Francisco 49ers quarterback Brock Purdy (toe) has been ruled out for Thursday night's matchup against the Rams, according to Ian Rapoport of NFL Network. Purdy made his return in Week 4 against the Jaguars after missing two games in a row, but is experiencing some lingering soreness and won't be ready to go on a short week. Purdy's return in Week 4 wasn't the cleanest of games as he turned the ball over three times in their home loss to Jacksonville. But he still managed to throw for over 300 yards and two touchdowns despite the miscues. Purdy will likely be good to go in games beyond this week, as the short week plays a big factor. Mac Jones will make his third start of the season in his place and will look to stay undefeated as a 49er.--Kyle McCarthy
Source: Ian Rapoport
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