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Fantasy football rankings - updated Week 16 FLEX (RB, WR, TE) rankings for 2025. Read the top-accuracy fantasy football PPR FLEX rankings.
A botched lineup call could cost you a spot in the fantasy football championship game, so check out our updated Week 16 fantasy football FLEX rankings for 2025 to guide your key start-sit decisions moving forward. In the ranking below, find out where notable RBs, WRs, and TEs such as DeVonta Smith, Tony Pollard, Stefon Diggs, Kenneth Gainwell, Michael Pittman Jr., Tetairoa McMillan, Jakobi Meyers, and more stand among all others.
Our FLEX fantasy football rankings for Week 16 are put together by Nick Mariano. Below the rankings, you will also find key fantasy football outlooks from our RotoBaller staff, as well as the "Who to Start?" tool. Also, be sure to check our fantasy football news for this week. There are always key injuries and developments to keep track of, so check back throughout the week for updates.
Be sure to bookmark our fantasy football rankings portal and check back regularly for updates. Most importantly, our free mobile app is a must-have - download it and configure your push notifications. We deliver all the top NFL news, injuries, and fantasy analysis 24x7 with our free push notification alerts... all for free!
Editor's Note: Stay on top of your draft prep with RotoBaller’s fantasy football rankings, featuring expert analysis, ADPs, and draft insights for both PPR and non-PPR leagues.
Week 16 FLEX Rankings for Fantasy Football
Bookmark our PPR rankings, Half-PPR rankings, and standard (non-PPR) rankings
Week 16 FLEX Rankings Outlooks
Tetairoa McMillan, Carolina Panthers
Carolina Panthers rookie first-round wide receiver Tetairoa McMillan (ankle, foot) has been cleared from the final Week 16 injury report and will suit up on Sunday for a big divisional matchup against the Tampa Bay Buccaneers. McMillan sat out of Wednesday's practice with ankle and foot injuries, but he returned to a full practice a day later and is ready to roll this weekend.
The 22-year-old from Arizona has been the Panthers' clear WR1 all year after being selected in the first round back in April, and he's produced 59 receptions, 851 receiving yards, and six touchdowns on his 102 targets through 14 games. McMillan doesn't have more than two catches in any of the last three games, but he's also scored twice and has four total touchdowns in the last four games. Coming off a two-catch, 25-yard dud last week against the Saints, fantasy managers are counting on a bounce-back performance in a big contest in Week 16.
Stefon Diggs, New England Patriots
New England Patriots wide receiver Stefon Diggs will look to get back on track in Week 16 against the Baltimore Ravens following a disappointing three-game stretch. Over his last three contests, Diggs has played fewer than half of the offensive snaps with just 11 targets, eight catches, 72 yards, and zero touchdowns. He ranks as the overall WR82 in full-PPR fantasy points per game during that span.
It has been a frustrating stretch for a veteran receiver who had previously strung together five consecutive contests with double-digit fantasy points. This week, he'll take on a Ravens secondary that has allowed the ninth-fewest fantasy points to slot receivers in 2025. That doesn't bode well for Diggs, who has played 49.8% of his snaps in the slot and has the 19th-most slot snaps in the NFL this year. Managers can absolutely justify benching the 32-year-old in fantasy leagues with 12 or fewer teams. He ranks as the overall WR31 in RotoBaller's latest fantasy football rankings for Week 16.
DeVonta Smith, Philadelphia Eagles
Philadelphia Eagles wide receiver DeVonta Smith tied his lowest target count in a game this season against the Raiders, mustering just two looks. He was not alone, however, as only one Philly player (Dallas Goedert) achieved more than three targets in the runaway victory. Plus, Smith was able to make the most of his little involvement, tallying 50 yards on two catches.
Coming up, he'll face off against a Commanders defense that has been weak against the pass this season. In fact, Washington has allowed more than 300 passing yards in three of their last six outings. However, Smith has not dazzled recently, having failed to find the end zone since Week 10 and tallying more than four receptions in a game just twice in that same span.
In what could be another game where Philly doesn't need to rely on throwing the ball, Smith may be outcasted yet again. The defensive matchup is favorable, but his involvement is no guarantee. Consider him a low-end WR3/FLEX this week.
Who Should I Start Tool
Not sure who to start? Check out the Who Should I Start tool:
Compare up to four players and we'll tell you who to start...
Who Should I Start? Who Should I Sit? Some common Week 16 fantasy football lineup decisions are regarding players like DeVonta Smith, Tony Pollard, Stefon Diggs, Kenneth Gainwell, Michael Pittman Jr., Tetairoa McMillan, Jakobi Meyers. But not to worry, we are here to help make these decisions and build winning lineups in Week 16.
Week 16 Player Decisions. Set your optimal fantasy football lineups for Week 16 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player's name. In the second box, search for the second player's name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.
Improvements For Who Should I Start? You may have noticed, we've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, enhanced search results with data to compare, and a slick new interface. We hope you enjoy!
How It Works. Each week, our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.
Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do is to select the scoring format. There are three small radio buttons (small circles), so click on the scoring format you prefer. The results may vary based on the scoring format you select.
Popular Week 16 Searches. Curious to see some tough lineup decisions for Week 16 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 16 Searches - Start/Sit Player Comparisons
Below are some popular Week 16 searches and comparisons from our 'Who To Start' tool:
More Fantasy Football Analysis
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