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FanDuel MLB DFS Lineup Picks (9/22/19): Daily Fantasy Baseball Advice

Troy Klauder highlights the top FanDuel MLB DFS lineup picks for 9/22/19, and a couple of sleepers to consider while building daily rosters.

We've got another exciting Sunday of baseball ahead of us!

This afternoon's main slate starts at 1:05pm ET and covers 11 games.

Be sure to also check out all the Vegas Odds for today's slate. You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @TroyKlauder

Happy New Year! Save 50% on any Premium Pass using discount code NEW. Win more with our DFS, Betting and Season-Long Pass, get expert tools and advice from proven winners! GAIN ACCESS

 

FanDuel DFS Pitchers

Matthew Boyd, DET vs CWS ($9,100) 

Boyd has been getting roughed up lately, but he's still an extremely high upside option thanks to his strikeouts, as he's got an elite 30.7% K-rate this year. His 3.83 Deserved Run Average and 3.56 SIERA suggest that he hasn't pitched as poorly as his ERA would lead you to believe. The White Sox strike out at a 24.0% clip against left-handed pitching, and although he's a volatile investment, Boyd's potential for a double digit strikeout performance makes him worth a look in GPP tournaments.

Marco Gonzales, SEA at BAL ($7,500) 

Gonzalez is a value starter to consider with his matchup against a weak opponent in the Orioles, who have just a .312 wOBA against lefties. He's coming off of back-to-back quality starts and can easily net a win - Gonzales surprisingly has 16 wins this year, and the Mariners offense can take advantage of Baltimore's abysmal pitching staff.

 

FanDuel DFS Infielders

Yasmani Grandal – C, MIL vs. PIT ($3,300) 

It's hard to find a catcher who can hit like Grandal, who has an .895 OPS and seven homers over the last month. He's a steal at this price batting second in a hitter-friendly park against Trevor Williams, who has an abysmal 5.59 ERA. The Brewers are a top stack option to consider.

Whit Merrifield – 2B, KAN at MIN ($3,300) 

Merrifield is a cash game play as the Royals leadoff hitter, as his extra plate appearances atop the lineup increase his floor. Of course, he's also in a great position to score runs against Martin Perez, owner of an ugly 4.92 ERA.

Kyle Seager – 3B, SEA at BAL ($3,500) 

Seager has been absolutely obliterating southpaws this season, with a phenomenal 150 wRC+ off of lefties. Take advantage of him in an extremely hitter-friendly ballpark in Baltimore.

Didi Gregorius – SS, NYY vs TOR ($3,400) 

Didi is in a spot to rack up counting stats batting third for the Yankees, who should put a beating on opposing starter Trent Thornton and his 4.99 ERA. With just a 15.1% K-rate, Gregorius's ability to put the ball in play works well in a hitter's environment at home in Yankee Stadium.

 

FanDuel DFS Outfielders

Aristides Aquino, CIN vs NYM ($3,400) 

Aquino is always worth considering in GPP contests when he's at home, where he's rocking a 1.045 OPS. Aquino should see some RBI opportunities batting fourth and is a must-play if you're chasing the long ball.

Eddie Rosario, MIN vs CLE ($3,500) 

There are a handful of starters to target on today's slate, but Jorge Lopez makes a strong case with as the weakest with his 5.16 FIP and 1.72 HR/9. Rosario stands out batting cleanup at a quite affordable price for a guy with 31 home runs and 101 RBI.

MLB DFS News and Injury Alerts




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REAL-TIME FANTASY NEWS

CFB

Jadan Baugh Staying with Florida for Junior Season
Washington Commanders

Commanders "Mutually" Parting Ways With OC Kliff Kingsbury
CFB

Byrum Brown Officially Commits to Auburn
CFB

Austin Simmons Signing with Missouri
Jake McCabe

to Sit Out One Week
Hampus Lindholm

to Miss Time
Christian Dvorak

Flyers Sign Christian Dvorak to Five-Year Extension
Igor Shesterkin

Exits With Lower-Body Injury Monday
Joel Armia

Hurt in Monday's Win
Anze Kopitar

Sustains Lower-Body Injury Monday
Tyler Herro

Questionable to Face Timberwolves
Ja Morant

Tagged as Questionable for Tuesday
Jalen Suggs

Considered Doubtful Tuesday
Jarrett Allen

at Risk of Missing Another Game
Donovan Mitchell

Resting Tuesday
Victor Wembanyama

Questionable Tuesday
Alperen Sengün

Alperen Sengun Possibly Out 10-14 Days
Moussa Diabaté

Moussa Diabate Returning Returning on Monday
Brandon Miller

Available on Monday Versus OKC
Kon Knueppel

Will Play Against OKC
Coby White

Back on Monday Night
Yanic Konan Niederhauser

Upgraded to Probable for Monday
Kon Knueppel

Probable For Monday
Matthew Schaefer

a Game-Time Call Tuesday
Jamie Benn

to Miss at Least Two Games
Seth Jones

Out Week-to-Week
James Harden

Lands on Injury Report Monday
Zach Bogosian

Unavailable Monday Night
Joel Embiid

Probable For Monday
Trevor Moore

Remains Out Monday
Aliaksei Protas

a Game-Time Call Versus Ducks
Jakob Poeltl

Sidelined at Least One More Week
Tom Wilson

Won't Play Monday
Jamal Murray

Sidelined Monday
CFB

Ty Simpson Undecided on 2026 Plans
CFB

Quarterback AJ Hill Following Ryan Silverfield to Arkansas
Atlanta Falcons

Falcons Have Requested an Interview With Klint Kubiak
Deshaun Watson

Browns Expect Deshaun Watson to be on the Team Next Year
Wan'Dale Robinson

Dealing With Fractured Ribs
Cam Skattebo

Hopes to be Back by Training Camp
Cameron Ward

Won't Need Surgery on his Shoulder
Davante Adams

Rams Expect Davante Adams to Return in Wild-Card Round
Arizona Cardinals

Cardinals Fire Head Coach Jonathan Gannon
Las Vegas Raiders

Raiders Fire Head Coach Pete Carroll
Malik Nabers

Unsure if He Will Be Ready for Week 1 of 2026 Season
CFB

Trinidad Chambliss Will Return to Ole Miss If Granted Sixth Year of Eligibility
Cincinnati Bengals

Zac Taylor Will Return as Bengals Head Coach in 2026
New York Giants

Giants Expected to Show Interest in Former Browns Head Coach Kevin Stefanski
Daniel Jones

Colts, Daniel Jones Appear to Have "Mutual Interest" in a 2026 Reunion
John Klingberg

to Sit Out at Least Three More Games
Cleveland Browns

Browns Fire Kevin Stefanski After Another Losing Season
Matthew Tkachuk

Joins Panthers for Road Trip
Connor Bedard

Set to Return Before Olympic Break
Jamie Benn

Injured in Sunday's Loss
Devon Toews

Not Expected to Make Quick Return
Gabriel Landeskog

to Miss "Some Time"
Zay Flowers

Goes Off for 138 Yards, Two Touchdowns in Loss
Bo Bichette

Phillies Have Interest in Bo Bichette
Amon-Ra St. Brown

Dominates in Week 18 Win
Cameron Ward

Believed to Have Grade 3 AC Joint Sprain in Right Shoulder
Colston Loveland

Leads Bears in Targets, Receptions, Receiving Yards in Week 18
Santi Aldama

Available on Sunday Evening
Ja Morant

Downgraded on Sunday Night
Puka Nacua

Finishes the Regular Season as Top-Scoring Receiver
Atlanta Falcons

Falcons Fire Raheem Morris and Terry Fontenot
David Njoku

Wants to Re-Sign with Browns
Giannis Antetokounmpo

Good to Go Against Sacramento
Trae Young

Won't Play on Monday Night
Kansas City Royals

Matt Quatraro Signs Three-Year Extension With Royals
Logan Stanley

to Sit Out One Game With Suspension
TOR

Chris Tanev Could Be Done for Rest of Regular Season
CFB

Transfer QB Billy Edwards Commits to North Carolina
CFB

Sam Leavitt Visiting Texas Tech on Saturday
CFB

DJ Lagway Expected To Visit Florida State
Kyle Tucker

Blue Jays "Remain the Favorite" to Sign Kyle Tucker
CFB

Joey Aguilar Undergoes Surgery to Remove Tumor on Friday
CFB

Texas the "Team to Beat" for Transfer Running Back Isaac Brown
CFB

Rocco Becht to Follow Matt Campbell to Penn State?
CFB

Texas Targeting Cam Coleman in Transfer Portal
CFB

Former Texas Running Back CJ Baxter Visiting Kentucky
CFB

Beau Pribula Visiting Virginia Tech, Georgia Tech
Bo Bichette

Yankees Showing Interest in Bo Bichette
Houston Astros

Astros Sign Tatsuya Imai to Three-Year Deal

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