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Saquon Barkley Has Chance to Return Against Panthers
Philadelphia Eagles running back Saquon Barkley (hamstring) could return for Sunday's Week 6 matchup against the Carolina Panthers, according to NFL Network's Mike Garafolo. Barkley suffered the injury early in the Week 4 loss to the Los Angeles Rams and missed Sunday's 19-17 defeat against Jacksonville. His availability will depend on how he progresses through practice this week, although there is some optimism that he could be ready to return. The 29-year-old has rushed for 182 yards on 36 carries through four appearances this season, averaging 5.1 yards per attempt without finding the end zone. Philadelphia's backfield has become increasingly depleted in his absence. Tank Bigsby (core muscle) remains on injured reserve, while Will Shipley suffered a partial tear of his plantar fascia against Jacksonville that could sideline him for multiple weeks. Dameon Pierce took over after Shipley's departure but managed just 14 yards on 11 carries as the Eagles finished with 22 rushing yards. Barkley would reclaim the lead role if healthy enough to play, making his practice participation especially important for fantasy managers preparing their Week 6 lineups.
Source: Mike Garafolo
Source: Mike Garafolo
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Saints Won't Say if Tyler Shough's Hand is Broken
When asked if quarterback Tyler Shough's left (non-throwing) hand is broken, New Orleans Saints head coach Kellen Moore was non-committal on Monday, according to Saints sideline reporter Jeff Nowak. "It got banged two weeks ago, and he's just wearing some protective layers there," Moore said. Shough got his second NFL season started out with a bang, but he has underwhelmed in each of the last two weeks in losses to the Atlanta Falcons and Minnesota Vikings. Facing one of the best defenses in the league in Minnesota on Sunday, Shough had his worst day at the offense through five games, going 16-for-25 passing for only 96 yards with no touchdowns and two interceptions in a 23-13 loss. He threw for 286 yards and one touchdown in the Week 4 loss to Atlanta after throwing for eight TDs and three interceptions in the first three games of 2026. Shough did not look right against Minnesota and could be playing through a broken hand, but that should not stop him from having bounce-back potential on the QB1/2 radar in Week 6 against the New York Giants.
Source: Jeff Nowak
Source: Jeff Nowak
DeVonta Smith Could Return After Two-Game Absence
Philadelphia Eagles wide receiver DeVonta Smith (hamstring) has a chance to return for Sunday's Week 6 matchup against the Carolina Panthers, according to NFL Network's Mike Garafolo. Smith has missed the past two games with a hamstring injury, but there are indications he could be available this weekend depending on how he progresses through practice. The 27-year-old was off to a productive start before getting hurt, catching 19 passes for 235 yards and one touchdown through three appearances. He was particularly effective against Tennessee in Week 2, hauling in 10 of 13 targets for 117 yards and a score. Smith entered the season as Philadelphia's clear No. 1 receiver following the departure of A.J. Brown and recorded 77 receptions for 1,008 yards in 2025. Rookie Makai Lemon and Darius Cooper have seen increased opportunities during his absence, with Cooper catching a 62-yard touchdown against Jacksonville on Sunday. Smith would immediately regain considerable fantasy appeal if he's cleared to play, although his practice participation will determine how realistic a Week 6 return becomes.
Source: Mike Garafolo
Source: Mike Garafolo
Roman Wilson Officially Ruled Out for Week 6
Pittsburgh Steelers head coach Mike McCarthy said on Monday that wide receiver Roman Wilson (finger) will not play in Week 6 against the Tampa Bay Buccaneers on Sunday, according to Nick Farabaugh of Penn Live. Wilson was worth a look off the waiver wire going into the Week 5 win over the Indianapolis Colts on Sunday after the Steelers placed receiver Michael Pittman Jr. (foot) on Injured Reserve. The 25-year-old was not able to take advantage of Pittman's injury, failing to haul in his only target against the Colts before leaving the game with a finger injury and never returning. In the first four games of the 2026 campaign, Wilson caught 26 of his 45 targets for 354 yards and two touchdowns while displaying clear chemistry with veteran quarterback Aaron Rodgers. Wilson is now in danger of missing the next couple of weeks due to his finger injury, so he will most likely head right back to the waiver wire in many fantasy leagues. With Wilson already out this week, rookie Germie Bernard is the waiver-wire name to target in Pittsburgh at the WR position.
Source: Penn Live - Nick Farabaugh
Source: Penn Live - Nick Farabaugh
Xavier Worthy Gains Week 6 Waiver Appeal Amid Receiver Injuries
Kansas City Chiefs wide receiver Xavier Worthy is worth targeting on waivers ahead of Week 6, with injuries potentially opening a larger role in the passing game. Kansas City returns from its bye with Tyquan Thornton (ankle) expected to land on injured reserve, while Rashee Rice (hamstring) remains day-to-day after exiting the Week 4 victory over Las Vegas. Worthy caught four of seven targets for a season-high 70 yards in that game, including a 41-yard reception, after totaling just 63 receiving yards over his first three contests. The third-year receiver has managed only 14 catches for 133 yards and one touchdown through four games, so there are still legitimate concerns about his weekly consistency. Rice could also return against the Los Angeles Chargers on Sunday, and Travis Kelce remains a significant part of the passing attack. However, Thornton's extended absence creates an opportunity for Worthy to become more involved downfield. Rostered in 58% of leagues and ranked sixth overall on RotoBaller's Week 6 waiver-wire board, Worthy warrants an add in leagues with 10 or more teams and carries WR3/FLEX upside if his opportunities increase.
Source: RotoBaller
Source: RotoBaller
Deebo Samuel Sr. "Going to Miss" A Couple of Weeks With Hamstring Strain
San Francisco 49ers head coach Kyle Shanahan said on Monday that wide receiver Deebo Samuel Sr. (hamstring) is "going to miss" a couple of weeks with the strained hamstring that he suffered in Sunday's Week 5 win over the division-rival Seattle Seahawks, according to David Lombardi of The San Francisco Standard. Fantasy managers should expect Samuel to miss the next two games against the Washington Commanders and Atlanta Falcons. San Francisco then has their bye in Week 8, so the earliest that Samuel might return could be Nov. 8 at home against the Las Vegas Raiders. It is yet another injury to a key receiver for the 49ers, leaving veterans Mike Evans and Brandin Cooks, who both scored touchdowns on Sunday, and Jacob Cowing as the 49ers' starting receivers going into a Week 6 matchup next Monday night against Washington. The 30-year-old Samuel caught just two passes for 21 yards and carried the ball two times for four yards in Week 5 before leaving in the third quarter and never returning. Samuel has taken on a big role so far in 2025 in his return to the Niners, with their receiving corps so banged up, and he has produced a nice 16-206-3 line for his fantasy managers.
Source: The San Francisco Standard - David Lombardi
Source: The San Francisco Standard - David Lombardi
Michael Penix Jr. Optimistic He Will Play in Week 6
Atlanta Falcons quarterback Michael Penix Jr. (ribs) injured his ribs late in the fourth quarter of the Sunday night loss to the Baltimore Ravens and was unable to take the field in overtime. The Athletic's Andy Behrens writes that Penix seemed optimistic about facing the Chicago Bears in Week 6. But for now, his status for Week 6 is in doubt as he heads for imaging on his ribs this week. If Penix is not cleared to face the Bears this weekend, Tua Tagovailoa, who threw an interception to seal the loss in overtime, could make his first start of the 2026 season. The Falcons also have Cooper Rush and Jack Strand in their QB room, so they have options if they want to avoid starting Tagovailoa. Falcons top receiver Drake London has caught 65 passes for 1,059 yards over his last nine games with Penix at QB, but he has struggled with anyone else under center, so his fantasy managers are surely hoping that Penix can play against the Bears. Until we have more details on Penix, he should be considered up in the air to play in Week 6.
Source: The Athletic - Andy Behrens
Source: The Athletic - Andy Behrens
Ja'Kobi Lane has a Chance to Return in Week 6
Baltimore Ravens head coach Jesse Minter said on Monday that rookie wide receiver Ja'Kobi Lane (wrist) has put himself in position to have a chance to come off Injured Reserve and return for the team's Week 6 tilt against the division-rival Cleveland Browns on Sunday, according to The Athletic's Jeff Zrebiec. This news should make fantasy managers run to the waiver wire to check on the 22-year-old third-rounder's availability. Lane caught just one of three passes for 11 yards in the Week 1 win over the Indianapolis Colts before fracturing his wrist. He also had a short touchdown reception called back due to a penalty. Lane was the buzz of Baltimore's training camp and preseason as a fast-rising rookie receiver who was quickly gaining chemistry with quarterback Lamar Jackson as a legitimate threat behind WR1 Zay Flowers. Lane's first year in the NFL hit an early roadblock, but he appears to be on the verge of a return and could quickly take over WR2 duties from veteran Rashod Bateman. Lane is only rostered in 8% of Yahoo leagues, so he is widely available to be picked up by fantasy managers searching for WR depth.
Source: The Athletic - Jeff Zrebiec
Source: The Athletic - Jeff Zrebiec
Jordyn Tyson Making Progress, but Practice Return Remains Uncertain
New Orleans Saints wide receiver Jordyn Tyson (hamstring) is progressing in his recovery, but a return to practice has not been confirmed. Asked Monday whether the rookie could begin practicing this week, head coach Kellen Moore responded, "Not right now," according to Mike Triplett, who added that Tyson is expected back on the practice field soon. The eighth overall pick in the 2026 NFL Draft has been sidelined since injuring his hamstring during an August 13 joint practice with Jacksonville. Tyson also dealt with hamstring issues before entering the NFL, which helps explain the team's cautious approach. He has been eligible to return from injured reserve since Week 5 but has yet to make his regular-season debut. Chris Olave has established himself as New Orleans' leading receiver with 39 catches for 537 yards through five games, while Devaughn Vele has added 25 receptions for 252 yards. Tyson remains an intriguing stash in deeper fantasy leagues, although his availability for Sunday's matchup against the New York Giants is uncertain, and his eventual role in the passing game has yet to be established.
Source: Mike Triplett
Source: Mike Triplett
Lamar Jackson Improving, Practice Status Undetermined
Baltimore Ravens head coach Jesse Minter said on Monday that quarterback Lamar Jackson (ankle) is definitely doing better, but he is unsure about whether Jackson will be able to practice on Wednesday as the team begins preparing for their Week 6 divisional clash with the Cleveland Browns, according to Jeff Zrebiec of The Athletic. "To his credit, he's doing everything he can to get back out there. What a wonderful teammate and leader he was even when he's not playing," Minter said. Jackson injured his left ankle in the Week 4 win over the Tennessee Titans and did not play on Sunday night in the team's road victory over the Atlanta Falcons, with backup QB Tyler Huntley running the offense. The 29-year-old is dealing with a unique ankle sprain, but there remains hope from the team that he will only have to miss one game. Jackson gives Baltimore's offense much more upside when he is under center, but perhaps Huntley's inspired play in primetime on Sunday night will give the Ravens more reason to slow-play Jackson's return. The former MVP will be a must-start against Cleveland this weekend if he returns to practice this week and is cleared to play on Sunday.
Source: The Athletic - Jeff Zrebiec
Source: The Athletic - Jeff Zrebiec
Pat Freiermuth Gains Week 6 Waiver Appeal After Two-Touchdown Game
Pittsburgh Steelers tight end Pat Freiermuth has put himself back in the waiver-wire conversation after catching five of seven targets for 44 yards and two touchdowns in Sunday's 34-22 victory over the Indianapolis Colts. He scored from one yard out in the second quarter before adding a 17-yard touchdown in the fourth, giving him four receiving scores through five games. Sunday's seven targets were a season high, and Freiermuth has now found the end zone three times over his past two contests. The touchdowns have helped offset some modest receiving totals, as he has just 19 catches for 169 yards and hasn't exceeded 46 yards in a game this season. Darnell Washington continues to compete for opportunities at tight end, although Freiermuth has drawn more targets so far. Pittsburgh's Week 6 matchup against Tampa Bay gives him another opportunity to produce, particularly for fantasy managers navigating bye weeks. Rostered in just 15% of leagues, Freiermuth is worth considering in 14-team formats and offers touchdown-dependent streaming value.
Source: RotoBaller
Source: RotoBaller
Jaylen Warren has Earned a Bigger Role in Pittsburgh
Pittsburgh Steelers running back Jaylen Warren has made a statement in the last three weeks as the workhorse RB1 for Pittsburgh with Rico Dowdle out due to a toe injury. Warren became the first player since Herschel Walker in 1986 to record a 50-yard touchdown run and an 80-yard touchdown catch in the same game in Sunday's Week 5 win over the Indianapolis Colts, according to ESPN's Brooke Pryor. He had 15 carries for 101 rushing yards and added six catches on six targets for 87 receiving yards and the two touchdowns. It was the third straight week (with Dowdle out) that Warren has had at least 125 all-purpose yards. No Steelers player has done that since James Conner did it four weeks in a row in 2018. Since Week 3, Warren has played at least 85% of the offensive snaps. Head coach Mike McCarthy said the Steelers hope to get Dowdle back in Week 6 against the Tampa Bay Buccaneers, but he also admitted that Warren has been thriving with a heavier workload. "He's hauling it right now for us. There's a number you'd like to continue to give him. He's produced, so it's been heavy. It'd be great to get Rico back this week, too," McCarthy said. Dowdle's eventual return will hurt Warren's overall fantasy ceiling, but he has earned more touches in the Steelers' backfield.
Source: ESPN.com - Brooke Pryor
Source: ESPN.com - Brooke Pryor
Dre Greenlaw Suspended One Game for Unsportsmanlike Conduct
San Francisco 49ers linebacker Dre Greenlaw has been suspended without pay for one game for an act of unsportsmanlike conduct during Sunday's Week 5 win over the division-rival Seattle Seahawks, according to Tom Pelissero of The Ringer. Greenlaw could appeal the suspension, which could allow him to play next Monday night to close out Week 6 action at home against the Washington Commanders. The 29-year-old made a poor decision to headbutt Seahawks linebacker Ernest Jones, who was not wearing a helmet, on the sidelines in Sunday's 32-29 win. Greenlaw was also suspended last year while with the Denver Broncos for unsportsmanlike conduct, so he will most likely lose his appeal. The former fifth-rounder by the Niners in 2019 from Arkansas has looked good so far in his return to the Bay Area, recording 37 tackles (18 solo) and a forced fumble in his five games played. If he is suspended for Week 6, Greenlaw's next chance to return will come on Oct. 25 against the Atlanta Falcons.
Source: The Ringer - Tom Pelissero
Source: The Ringer - Tom Pelissero
Packers Not Expecting Micah Parsons to Practice This Week
The Green Bay Packers are not expecting standout pass-rusher Micah Parsons (knee) to return to practice this week as the team prepares for a big Sunday night game in Week 6 against his former team, the Dallas Cowboys, sources told Adam Schefter of ESPN. There is still uncertainty about exactly when Parsons will return from the torn ACL that he suffered in late December last year, but the hope still remains that he will make his 2026 debut in October. The 27-year-old five-time Pro Bowler and three-time first-team All-Pro was hoping he could make his return against his old team this weekend, but it looks like that will not happen after all. The following week -- a Week 7 date with the division-rival Detroit Lions -- could also be a long shot for Parsons, who will not necessarily return right away from the Physically Unable to Perform list once he begins practicing with the rest of the team. Parsons is a one-man wrecking crew when he is 100%, and the Packers are hoping that they can use him again sooner rather than later. In 14 games in 2025 after being acquired from Dallas, Parsons was on pace to shatter his career highs, recording 12.5 sacks, 41 tackles (19 solo), 12 tackles for loss, and 27 QB hits.
Source: ESPN - Adam Schefter
Source: ESPN - Adam Schefter
Browns Could Open Dylan Sampson's Practice Window This Week
Cleveland Browns head coach Todd Monken said that there is a "possibility" that the team opens running back Dylan Sampson's (knee) 21-day practice window this week to return from Injured Reserve, according to Daniel Oyefusi of ESPN. Sampson has missed the last four games with a knee injury. Cleveland's backfield depth is being tested with Sampson out and lead back Quinshon Judkins is now day-to-day after tweaking his ankle in the Week 5 loss to the New York Jets on Sunday. Judkins was seen wearing a walking boot after the game on Sunday, and Raheim Sanders (hip) is also questionable for Week 6 against the division-rival Baltimore Ravens after he was injured against the Jets. The only other RB currently on the active roster is Jaleel McLaughlin, so at the very least, McLaughlin could be bumped up to the RB2 role this weekend. If Sampson returns to practice this week, it does not guarantee he will officially be activated from IR and play on Sunday against Baltimore. Sampson did not have a single touch in the Week 1 loss to the Jacksonville Jaguars.
Source: ESPN.com - Daniel Oyefusi
Source: ESPN.com - Daniel Oyefusi
Quinshon Judkins Day-to-Day With Ankle Injury
Cleveland Browns head coach Todd Monken is not ruling anyone out for Sunday's divisional clash in Week 6 against the Baltimore Ravens, according to Scott Petrak of The Chronicle-Telegram. Monken added that Judkins is day-to-day after tweaking his ankle in the Week 5 loss to the New York Jets on Sunday. The 22-year-old second-year back played only 52.9% of the offensive snaps in the 17-12 loss in New York and handled 14 carries for 44 yards (3.1 yards per attempt) while catching three of his four targets for six yards. Judkins was seen in a walking boot after the game. Backfield mate Raheim Sanders (hip) was also injured in the same contest and left the game, so Cleveland's backfield depth could be tested at a bad time against the Ravens' defense this weekend. Judkins has underwhelmed so far as an RB in fantasy so far in 2026 in his second year in the league, averaging 3.0 yards per carry for 221 yards and one touchdown in four games, adding 18 receptions for 102 yards as a receiver. The only other RB on the Browns' current roster is Jaleel McLaughlin. Fantasy managers will need to keep a close eye on Judkins' status from Wednesday through Friday.
Source: The Chronicle-Telegram - Scott Petrak
Source: The Chronicle-Telegram - Scott Petrak
Jordyn Tyson Remains a Critical Stash Despite No Signs of Return
As NFL bye weeks continue to roll in and injuries pile up around the league, fantasy bench space becomes all the more critical, but New Orleans Saints wide receiver Jordyn Tyson (hamstring) remains one of fantasy's most valuable stashes, despite no clear indication of a return from the hamstring injury that landed him on injured reserve to begin the year. The eighth overall pick in the 2026 NFL Draft, Tyson was a training camp standout, and he has the potential to form one of the league's most productive tandems with Chris Olave upon his eventual return. Even after a poor Week 5 showing, Olave is the WR5 through five weeks, while quarterback Tyler Shough remains in the top 10, with Kellen Moore's up-tempo offense helping to create a rich fantasy environment in which Tyson is projected to thrive.
Source: RotoBaller
Source: RotoBaller
Jalen Coker "On Track" to Return in Week 6
Following the team's Week 5 bye, Carolina Panthers wide receiver Jalen Coker (quad) is on track to return for a Week 6 matchup with the Eagles, according to head coach Dave Canales and The Athletic's Joe Person. Coker has been dealing with a quadriceps injury and missed the team's Week 4 win over the Lions, but Canales told the media on Monday that he has a couple of big days of practice ahead of him. Coker led the team in receptions and yards through the first three games, but in his absence, 2025 Offensive Rookie of the Year Tetairoa McMillan exploded for career highs of 14 catches and 192 yards, adding two touchdowns in the win over Detroit. The potential return of Coker likely hurts McMillan's overall ceiling, but if both receivers can stay involved, Carolina's surprising offense should remain one of the league's most fantasy-friendly moving forward.
Source: Joe Person
Source: Joe Person
Brian Robinson Remains One of Fantasy's Most Valuable Insurance Backs
After recording a career-high three rushing touchdowns in a Week 4 win over the Saints, Atlanta Falcons running back Brian Robinson became one of the most popular waiver pickups of the week, but he was unable to make a second straight fantasy contribution, rushing for only 16 yards in Sunday night's loss to the Ravens. As one of fantasy's premier handcuffs behind All-Pro running back Bijan Robinson, the former Robinson remains roster-worthy in almost all formats and is a player managers should be on the watch for after the week's first wave of drops. Quarterback Michael Penix Jr. (ribs) was injured late in the loss to the Ravens, and if veteran Tua Tagovailoa is forced into the starting role, the Falcons' entire offensive ceiling takes a hit, but in a Week 6 matchup with the Bears, both Robinsons should be able to find more open running lanes.
Source: RotoBaller
Source: RotoBaller
Zach Charbonnet a Must-Add Wherever Still Available
Seattle Seahawks running back Zach Charbonnet (knee) had his 21-day practice window opened on October 1, and while he is not expected to be activated ahead of the team's Week 6 Thursday night tilt with the Broncos, he still needs to be rostered in all league formats. First-round rookie Jadarian Price (chest) is on injured reserve with a chest injury, leaving the Seahawks to piece together the position with Emanuel Wilson and George Holani. As a result, running back has become an obvious weak spot on an otherwise championship-caliber roster, particularly as ball-security issues continue to pop up. Price, Wilson, and Holani have combined for six fumbles through five games, and while Charbonnet has had his detractors, he has never fumbled on 432 professional carries, and he figures to earn a sizable role as soon as he is made active.
Source: RotoBaller
Source: RotoBaller
Dameon Pierce a Worthwhile Waiver Pickup in Eagles' Thinning RB Room
Philadelphia Eagles running back Dameon Pierce led the team with a 61.1% running back rush share in a Week 5 loss to the Jaguars, and although he was only able to rack up 12 total yards on his 15 opportunities, he is a player who should be rostered ahead of the Eagles' Week 6 matchup against a more forgiving Panthers defense. With All-Pro Saquon Barkley (hamstring) sidelined with a hamstring injury, Pierce was elevated from the practice squad and more than doubled Will Shipley's opportunities and touches in what remained a relatively neutral game script. While the results were not there against a formidable Jaguars front, the Panthers have been the third-best fantasy matchup for running backs, and if Barkley misses another week, Pierce can be considered as a flex play in deeper leagues.
Source: RotoBaller
Source: RotoBaller
More News About Saquon Barkley
