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San Francisco 49ers wide receiver Brandon Aiyuk (knee) has yet to have his practice window opened, as he continues to recover from the multi-ligament knee injury that ended his 2024 season prematurely. While there's been speculation, he could miss all of 2025, general manager John Lynch recently noted that Aiyuk is "getting better and closer to a return." If he does make it back this season, Aiyuk will likely be eased in gradually, as most receivers returning from a major knee injury need time to regain form. By the time he's ready, the 49ers' receiving corps should be back at full strength, which could limit his target share in 2025. Fantasy managers should keep Aiyuk stashed in IR spots and remain cautiously optimistic about a late-season return.--Nathan Harvey
Source: Pro Football Reference
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REAL-TIME FANTASY NEWS

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