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Who Should I Start for MNF Week 5? Fantasy Football outlooks for Travis Etienne Jr., Isiah Pacheco, Patrick Mahomes, Xavier Worthy, Hollywood Brown, Bhayshul Tuten, Travis Hunter, Travis Kelce, Kareem Hunt, Brian Thomas Jr.
Who Should I Start? Who Should I Sit? Some of the most common Week 5 fantasy football lineup decisions for Monday Night Football (MNF) involve players like Travis Etienne Jr., Isiah Pacheco, Patrick Mahomes, Xavier Worthy, Hollywood Brown, Bhayshul Tuten, Travis Hunter, Travis Kelce, Kareem Hunt, Brian Thomas Jr. However, don't worry, we are here to help you make these decisions and build winning lineups in Week 5. Set your optimal fantasy football lineups for Week 5 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
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Fantasy Football Matchup Outlooks
Below are some fantasy football outlooks written by our NFL team here at RotoBaller, bringing you their fantasy football analysis and advice on which players to consider starting in Week 5:
Travis Etienne Jr., RB, Jacksonville Jaguars
The Jacksonville Jaguars face off with the Kansas City Chiefs on Monday Night Football in what should be a difficult matchup. Travis Etienne Jr. at running back might be the only bright spot for this game, as the passing offense has struggled to get going so far this season.
If the Jaguars want to have any chance to win this game, they will need Etienne Jr. to run well and often to control possession. He has been solid so far this season, sitting currently as the RB10 in half-PPR scoring.
However, with the Chiefs having a good defense and the Jaguars offense being unreliable, it is hard to vault the starting back into RB1 status. Start Etienne Jr. with decent confidence in Week 5
Isiah Pacheco, RB, Kansas City Chiefs
Kansas City Chiefs running back Isiah Pacheco will face the Jacksonville Jaguars on Monday night in Week 5. Pacheco rushed seven times for 35 yards (5.0 yards per carry) and caught two passes for 13 yards and a touchdown in last week's win over the Baltimore Ravens.
Pacheco finished second in carries and rushing yards in Week 4, but he's locked into a backfield committee with Kareem Hunt and Brashard Smith. Hunt finished last week's game with the most carries, and Smith's involvement in the offense has increased each week. Pacheco will have to contend with backfield competition and the Jaguars, who allow the eighth-fewest fantasy points to opposing running backs.
The 26-year-old should continue handling RB2 duties this Monday night, but it will be interesting to see how the touches are divided. Pacheco is ranked RB35 in our RotoBaller Half-PPR rankings, putting him in the RB3/Flex conversation this week.
Patrick Mahomes, QB, Kansas City Chiefs
Kansas City Chiefs quarterback Patrick Mahomes was listed on the injury report with a groin injury this week, but practiced fully and does not have an injury designation heading into Monday night. The Chiefs will take on the Jacksonville Jaguars on Monday night in Week 5.
Mahomes completed 25 of 37 pass attempts (68%) for 270 yards and four touchdowns. His Week 4 performance was easily his best of the season as a passer, reaching new season-highs in completions, completion percentage, passing yards, and passing touchdowns. The 29-year-old will look to build on that impressive performance against the Jaguars, who are middle-of-the-pack in fantasy points allowed to opposing quarterbacks this season.
The Kansas City superstar's best game of the year coincided with the return of Xavier Worthy, so maybe the duo can keep the good times rolling in a game with the sixth-highest total this week. Mahomes is ranked QB2 in our RotoBalller rankings, making him a must-start QB1 this week.
Xavier Worthy, WR, Kansas City Chiefs
Kansas City Chiefs wide receiver Xavier Worthy (shoulder, ankle) is expected to play against the Jacksonville Jaguars in Week 5 despite being listed as questionable, according to Matt Verderame of Sports Illustrated.
The Chiefs made a late adjustment to their injury report that called Worthy's status into doubt just 24 hours before kickoff, but Verderame has reassured fantasy managers that "the expectation is [Worthy] will be okay."
Nevertheless, given the timing of Monday Night Football, managers might want to add someone like JuJu Smith-Schuster or Tyquan Thornton, who can be seamlessly inserted into lineups if Worthy suffers a setback and can't play against the Jaguars.
Brian Thomas Jr., WR, Jacksonville Jaguars
The Jacksonville Jaguars face the Kansas City Chiefs on Monday Night Football and will look to use the primetime game as a jumping-off point for the offense.
Fans had high hopes for the team's offense with head coach Liam Coen entering the fold, but so far it has underwhelmed, mainly due to the performances of wide receiver Brian Thomas Jr. The second-year man will look to bounce back in a big way on national television, but that is something managers have been hoping for each of the past few weeks.
BTJ was a force to be reckoned with last season, but in Week 5, fantasy managers may have to continue waiting for this year's reckoning in a tough matchup with the Chiefs' secondary.
Who Should I Start Tool
You can also see the Who Should I Start tool here.
Week 5 Monday Night Football Player Decisions. Today's focus is on specific players - Travis Etienne Jr., Isiah Pacheco, Patrick Mahomes, Xavier Worthy, Hollywood Brown, Bhayshul Tuten, Travis Hunter, Travis Kelce, Kareem Hunt, Brian Thomas Jr. These are some of the most common searches for fantasy football lineups in Week 5.
Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player name. In the second box, search for the second player name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.
Improvements For Who Should I Start? You may have noticed that our 'Who Should I Start?' tool has gotten an overhaul. We've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, stats, projections, strength of schedule, players news, and enhanced search results with data to compare with a slick new interface. We hope you enjoy!
How It Works. Each week our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.
Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do, is to select the scoring format. There are three small radio buttons (small circle), so click on the scoring format you prefer. The results may vary based on the scoring format you select.
Popular Week 5 Searches. Curious to see some tough lineup decisions for Week 5 Monday Night Football (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 5 Searches - MNF Start/Sit Player Comparisons
Below are some popular searches and comparisons from our Who To Start tool for Week 5 for Travis Etienne Jr., Isiah Pacheco, Patrick Mahomes, Xavier Worthy, Hollywood Brown, Bhayshul Tuten, Travis Hunter, Travis Kelce, Kareem Hunt, Brian Thomas Jr.:
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