
Read Trey Sermon's fantasy football outlook for Week 3 of the NFL season. Notes, updates, analysis and advice including predictions for his upcoming matchup.
It's been a wild ride for Trey Sermon, the San Francisco 49ers, their running backs and fantasy football managers. After being touted as a sneaky and savvy draft pick for fantasy football, Sermon was surprisingly scratched in Week 1 even thought he was healthy. Elijah Mitchell emerged, and then in Week 2 all three 49ers running backs got injured. Mitchell sustained a shoulder injury, JaMycal Hasty came up with an ankle injury, and in his first career NFL carry Trey Sermon was knocked out of the game with a head injury. That brings us to Week 3.
Trey Sermon has now been cleared from the NFL's concussion protocol and wasn't listed on the final injury report for Week 3. He is looking to be in line to start against the Green Bay Packers on Sunday Night Football. JaMycal Hasty has already been ruled out for the game, and Elijah Mitchell is being called doubtful. A perfect storm for Sermon?
It doesn't inspire much confidence that Sermon only has one career carry and was a healthy scratch in Week 1. But the 49ers run the ball a lot, and tend to have a next-man-up mentality when it comes to running backs. At the very least, it's looking like Sermon will get a solid amount of touches in Week 3, but that could change if Mitchell suits up or if Trenton Cannon or Jacques Patrick are worked into the game plan. For now, fantasy managers should consider Sermon an RB3/FLEX option, and can roll the dice on him in deeper leagues or on rosters that are already facing an injury crunch.
Be sure to check all of our fantasy football rankings for 2025:- 2025 fantasy football rankings (redraft)
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