Sep 12, 2026, 9:41 AM ET

Arizona Cardinals quarterback Jacoby Brissett is returning to helm the team's offense after signing a one-year, $15.5 million contract in the offseason. Brissett succeeded Kyler Murray as Arizona's starting quarterback after Murray's season was ended by a severe foot sprain in Week 5. In 12 starts, Brissett threw for 3,366 yards, 23 touchdowns, and eight interceptions, and averaged 40.3 pass attempts per game. His production made him the QB7 measured by fantasy points per game. To kick off 2026, Brissett will face a challenging Chargers defense. With rookie running back Jeremiyah Love questionable and the Cardinals likely to be playing from behind, Arizona may be forced into a pass-heavy script. He will be a risky start in single-quarterback leagues but is a good play in two-QB or superflex leagues based on his potential volume.--Dan Stephens
Source: NFL.com

Sep 12, 2026, 9:35 AM ET

Tennessee Titans running back Tony Pollard has been a consistent and durable rusher in recent years, recording at least 1,000 rushing yards and 1,250 scrimmage yards in four consecutive seasons. Entering 2026, Pollard once again profiles as the lead back in Tennessee. He's scored just 10 touchdowns over his first 33 games with the Titans, but the team should field its best offense in recent memory in quarterback Cam Ward's second year as the starter. In Week 1, Pollard and the Titans will host the New York Jets. New York struggled to defend the run in 2025, allowing the fourth-most rushing yards (2,371) in the NFL. Given that neither team projects to have a particularly explosive passing game, Tennessee could choose to lean heavily on the run game and give Pollard plenty of work on Sunday. It's hard to bank on Pollard providing high-end production given the questions that remain in the Titans' overall offensive attack, but he profiles as a high-floor flex option for fantasy managers in Week 1.--Will Brady
Source: RotoBaller

Sep 12, 2026, 9:29 AM ET

Los Angeles Chargers wideout Quentin Johnston has an opportunity to start the NFL season with a bang on Sunday at home against the Arizona Cardinals. The 25-year-old was WR4 overall in PPR scoring and averaged 19.9 points per game during the first four games last season. He eventually cooled off due to injuries to himself and around him that deflated the offense down the stretch. Johnston will get to face off against a Cardinals defense that allowed the sixth-most passing touchdowns (31), ninth-most completions (375), and 10th-most passing yards (4,128) last season. In addition, they gave up the 12th-most passes of 20 or more yards, which benefits a vertical threat like Johnston. He has already displayed his deep-threat ability in Mike McDaniel's offense during the preseason finale, where Justin Herbert connected with him on a 65-yard touchdown. He's RotoBaller's PPR WR39 and is a flex option with upside for fantasy managers in Week 1.--Wyatt McClintock
Source: NFL.com

Sep 12, 2026, 9:27 AM ET

Tennessee Titans quarterback Cam Ward had an up-and-down season as a rookie in 2025, completing 59.8% of his pass attempts for 3,169 yards, 15 touchdowns, and seven interceptions. Entering 2026, the 24-year-old remains the unquestioned QB1 in Tennessee and should have a better supporting cast around him after the Titans added rookie Carnell Tate and veteran Wan'Dale Robinson to their wide receiver room over the offseason. In Week 1, Tennessee will host the New York Jets. The Jets fielded a bottom-tier pass defense in 2025, allowing the most passing touchdowns in the NFL (36) while also failing to record a single interception for the entire season. However, New York added some veteran talent over the offseason and should field an improved unit in 2026. Ward is also coming off a shaky preseason, and the team's overall offense remains a question mark heading into the year. Given the uncertainty, Ward profiles as a low-end QB2 option for fantasy at best in Week 1.--Will Brady
Source: RotoBaller

Sep 12, 2026, 9:24 AM ET

Los Angeles Chargers wideout Ladd McConkey is set for a strong outing this Sunday at home against the Arizona Cardinals. The 24-year-old is coming off a sophomore slump season, as his receiving stats dipped after sharing targets with Keenan Allen. However, Allen is in Indianapolis this season, and McConkey will face a Cardinals defense that ranked top 10 in targets, catches, and total receiving yards in 2025, according to Kyle Dvorchak of NBC Sports. In addition, the Cardinals surrendered the sixth-most passing touchdowns and the 11th-highest completion percentage. McConkey is expected to reprise his role as the team's slot receiver for Mike McDaniel, who weaponized slot receivers during his tenure in Miami. He is RotoBaller's PPR WR17 in a favorable matchup and could end up as a WR1 in Week 1.--Wyatt McClintock
Source: NFL.com

Sep 12, 2026, 9:21 AM ET

Los Angeles Chargers running back Omarion Hampton will make his 2026 debut in Mike McDaniel's offense with a favorable home matchup against the Arizona Cardinals on Sunday. The 23-year-old had an injury-riddled rookie campaign but finished as the RB12 in fantasy points per game (15.1) among running backs who played at least nine games, despite a shaky offensive line. McDaniel has been very fantasy-friendly with running backs and has produced a top-5 fantasy running back in each of the last three seasons, with four running backs averaging over 17 fantasy points per game. In Week 1, Hampton draws a Cardinals defense that allowed the sixth-most 20-plus yard carries, eighth-most rushing yards, ninth-most rushing touchdowns, and the 12th-most rushing yards per carry last season. He's RotoBaller's Half-PPR RB9 in a favorable matchup that could lead to a heavy workload if the Chargers get a healthy lead in the second half.--Wyatt McClintock
Source: NFL.com

Sep 12, 2026, 9:20 AM ET

New York Giants wide receiver Malik Nabers (knee) is medically cleared to play in Week 1 but remains a game-time decision, per ESPN's Jeremy Fowler. Fowler reports that the Giants are "prepared for (Nabers) to play," but that the decision is ultimately "up to (Nabers) and how he feels." The 23-year-old is working his way back from the devastating knee injury that ended his 2025 season in Week 4. Given the severity of the injury and the length of his absence, the thought is that both the team and player are taking a long-term view of his recovery rather than focusing on rushing him back out onto the field. The Giants play the Dallas Cowboys in Sunday Night Football, so fantasy managers may have to decide whether or not to leave Nabers in their lineups before knowing for sure if he will be active. If Nabers is unable to play, Giants wideouts Darnell Mooney, Malachi Fields, and Odell Beckham Jr. could all be available on the waiver wire and would likely see increased workloads.--Will Brady
Source: ESPN - Jeremy Fowler

Sep 12, 2026, 9:17 AM ET

Los Angeles Chargers quarterback Justin Herbert will make his 2026 debut in Mike McDaniel's offense with a favorable home matchup against the Arizona Cardinals on Sunday. The 28-year-old is coming off a solid fantasy football campaign, finishing as the QB10 in overall scoring and points per game (18.7) last year. Herbert is expected to get a statistical boost this season with McDaniel's as the offensive coordinator, who has orchestrated one of the league's most explosive offenses and has led the league in passing yards before. The quarterback-coordinator duo will face a Cardinals pass defense that finished near the bottom in most passing stats last year. They allowed the sixth-most passing touchdowns (31), ninth-most completions (375), 10th-most passing yards (4,128), 11th-highest completion percentage (65.6), and had the third-fewest sacks (30). In addition, the Cardinals will deploy a similar defensive scheme after keeping Nick Rallis as their defensive coordinator and making no big additions on defense this offseason. Herbert is RotoBaller's QB4 in a dream matchup and has it within his realm of outcomes to be the QB1 overall in Week 1.--Wyatt McClintock
Source: NFL.com

Sep 12, 2026, 9:10 AM ET

Chicago Bears wide receiver Rome Odunze (calf) is not yet medically cleared to play in his team's season opener against the Carolina Panthers, per ESPN's Jeremy Fowler. Odunze has been battling a calf strain and is officially listed as questionable to play. The 24-year-old told reporters on Friday that he feels "ready to go," but Fowler reports that the team will ultimately be making the call on whether to have him suit up on Sunday. Odunze had the tail end of his 2025 campaign disrupted by a nagging foot injury, so Chicago's decision-makers may be looking to avoid a similar situation where the calf issue lingers in 2026. If Odunze is active, he profiles as a flex option for fantasy managers in Week 1. If he's unable to go, Bears tight end Colston Loveland and wide receiver Luther Burden III would both likely see increased workloads.--Will Brady
Source: ESPN - Jeremy Fowler

Sep 12, 2026, 8:39 AM ET

Carolina Panthers wide receiver Xavier Legette (ankle) was not listed on the team's injury report and will suit up against the Chicago Bears in Week 1. Legette injured his ankle during practice a few weeks ago but has been cleared and will be active for the regular season opener. The 25-year-old is set to be Carolina's WR3 behind Tetairoa McMillan and Jalen Coker after catching 35 passes for 363 yards and three touchdowns last season. The Bears' secondary is banged up heading into Week 1 and will be without safety Coby Bryant and cornerback Kyle Gordon. Chicago also allowed the third most fantasy points to wideouts last year, giving Legette a plus matchup for this week. Despite the positive matchup and game script (47.5 points over/under), Legette is an option in very deep leagues and is ranked WR90 in the latest RotoBaller rankings for Week 1.--Brad Camara - RotoBaller
Source: RotoBaller

Sep 12, 2026, 8:34 AM ET

Miami Dolphins tight end Greg Dulcich has the potential to develop into a top target in his team's passing game this season. With new QB Malik Willis expected to lead a run-heavy and conservative offense, Dulcich is expected to be the team's top pass-catching tight end. The team could also rotate rookies Will Kacmarek, Seydou Traore, and Justin Joly in what could be an interesting timeshare to monitor. Dulcich had 26 catches for 335 yards and a touchdown while playing 10 games for the Dolphins last year. He's the lone veteran in the tight end room coming into the year, and even though he has the potential to fill a growing role, he's a very high-risk start in Week 1, despite a favorable matchup against the Raiders in Las Vegas. Dulcich is the No. 30 TE in RotoBaller's Week 1 rankings, so even though he has sleeper potential, it's best to see how the timeshare works out before using any of the Dolphins' tight ends for fantasy.--Zach Thompson
Source: RotoBaller

Sep 12, 2026, 8:32 AM ET

Indianapolis Colts quarterback Daniel Jones (Achilles) is set to take the field Sunday afternoon at home against the Baltimore Ravens for the first time since going down in Week 14 amidst a breakthrough season last year. He was QB13 in fantasy points per game through the first 13 weeks of the 2025 season and was a starter/streaming option for many fantasy managers prior to his injury. Jones' mobility in his first live NFL snap since his right Achilles tear will be a major item of interest in Week 1, but it is unclear how the new Ravens defense will apply pressure. Last year, the Ravens generated the fourth-lowest pressure rate (27.0%) on plays using a four-man pass rush, their lowest mark since 2017. According to Next Gen Stats, in 2025, Jones averaged 8.6 yards per attempt when facing a four-man pass rush through the first 13 weeks prior to suffering his season-ending injury, trailing only Drake Maye (8.9). However, newly acquired Ravens edge rusher Trey Hendrickson has aligned as the right edge on 94.2% of his snaps since 2021, projecting a matchup with Colts left tackle Bernhard Raimann. In their lone prior meeting in Week 14 of 2023, Hendrickson generated seven pressures, including two sacks, across 21 pass-rushing matchups against Raimann, resulting in a 33.3% pressure rate, also according to Next Gen Stats. Admittedly, plenty has changed since that duel almost three years ago, but that potential pressure coupled with the uncertainty surrounding Jones' post-Achilles injury mobility is a concern for his overall fantasy value this week. Jones is Rotoballer's QB23 heading into Sunday, putting him on the edge of superflex consideration in 12-person or larger leagues for Week 1.--Matt McCauley
Source: ESPN

Sep 12, 2026, 8:31 AM ET

Carolina Panthers tight end Darren Waller signed a one-year contract with the Panthers this offseason and is expected to be the team's starting tight end. Waller practiced all week and recently worked with the first-team offense, with the plan to play in Week 1 against the Chicago Bears. According to Steve Reed of the Associated Press, Waller is not on the injury report for Week 1, but continues to ramp up his conditioning after joining the team in mid-August. The 33-year-old caught 24 passes for 283 yards and six touchdowns in nine games for the Dolphins last season. He gives quarterback Bryce Young a red zone weapon, but the Bears were stingy against tight ends last year, allowing the second-fewest fantasy points to the position. Waller ranks 31st in our tight end rankings and is mainly an option in deep-league TE premium leagues heading into Week 1. Even if Waller is active, he should be left on the bench and is a dart throw at best for the regular season opener.--Brad Camara - RotoBaller
Source: RotoBaller

Sep 12, 2026, 8:22 AM ET

Miami Dolphins wide receiver Chris Bell was named as one of the team's starting receivers in his NFL debut in Week 1 against the Las Vegas Raiders. An ACL tear ended his college career at Louisville and caused him to slide to the third round of the 2026 NFL Draft. Even though he missed most of his first training camp while rehabbing, he has made a splash right away with a quick acclimation to the Dolphins' offense. He only played one preseason game, but he was targeted five times in about 10 minutes of game action. In Week 1, Bell is RotoBaller's WR73, just behind teammates Caleb Douglas and Malik Washington. Bell could end up being the top fantasy receiver in Miami's offense at some point this season, and he has a huge opportunity ahead of him. He's extremely high risk for Week 1, but he's a rookie to monitor moving forward.--Zach Thompson
Source: RotoBaller