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Nov 12, 2025, 10:59 AM ET

ESPN's Adam Schefter reports that Arizona Cardinals wide receiver Marvin Harrison Jr. (appendix) underwent surgery for appendicitis and will be sidelined for "at least this week and possibly longer." It's a tough blow for the 23-year-old, who had recorded 10 catches for 129 yards and two touchdowns on 22 targets over the last two weeks. Harrison Jr. will now miss his team's Week 11 matchup against the San Francisco 49ers, and it appears there's no guarantee he'll be back in Week 12 to face the Jacksonville Jaguars. Without Harrison Jr. on the field, Arizona tight end Trey McBride could see an even larger target share. Additionally, Cardinals wideout Michael Wilson could be in line for significantly more looks from quarterback Jacoby Brissett. Wilson saw a season-high seven targets in Week 10 and may be in for another target spike in Week 11.--Will Brady
Source: ESPN - Adam Schefter
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