🖥 CYBER WEEK - TAP TO SAVE 50% WITH CODE CYBER
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

MLB DFS Lineup Picks - Early Slate (5/27/21): DraftKings, Daily Fantasy Baseball

Jorge Pucks highlights the top DraftKings, DanDuel MLB DFS lineup picks for the "Early" slate on 5/27/21, and a couple of sleepers to consider while building daily rosters.

Hello there, MLB DFS grinders! We have a split Thursday slate and the focus on this article will on the four/five-game early only slate for both DraftKings and FanDuel. With the Mets and Colorado game being included on DK, they decided to make their slate a five-game slate but the only interest I have in that particular game would be Marcus Stroman. Outside of that, I am planning on drilling down and focusing on those other four games.

While most of our MLB DFS coverage here at RotoBaller is geared towards the main slate, I wanted to give you some of my favorite pitchers and bats for these early games that will help you cash in tournaments and cash game contests. I'll highlight my favorite pitching options here first and then give you some hitters at each price tier to consider as well as my favorite teams to stack up! You can read our DraftKings DFS lineup picks for the main slate and FanDuel DFS lineup picks for the main slate as well.

I'll be providing you with my daily fantasy baseball lineup picks for the FanDuel and DraftKings early only slate at 12:10 PM on 5/27/2021. Be sure to also check out all the MLB player news, including late scratches, and the projected and confirmed daily MLB lineups for each DFS slate. You can also check out today's MLB DFS lineup picks for the main slate here, and read more DFS advice and lineup picks for other sports too. Let's get to it!

 

MLB DFS Pitchers

Shane Bieber @ DET ($10,800 DK, $11,300 FD)

Bieber is the top option on both sites so paying up for him would be the move, especially in cash game formats. The Tigers as a team have the third-most strikeouts against right-handed pitching and Bieber is generating a 34.3% outside the zone swinging percentage and is getting ahead in the count over 55% of the time. Bieber has had at least six strikeouts in every start this season and in his lone start against the Tigers, he went six innings while giving up three runs on five total hits and striking out 12 so there is a high ceiling for this matchup.

Pablo Lopez vs. PHI ( $9,400 DK, $8,900 FD)

Another option to consider on this slate is Pablo Lopez. Lopez will be pitching in his home park down in Miami which has generally been viewed as a pitcher's park and gets a lineup that is missing its most dangerous bat in Bryce Harper. The Phillies lineup is generating a 25% strikeout percentage against right-handed pitchers and has a team ISO of just .146 against this handedness. Lopez looks to be in good form right now as he is coming off his best start of the season where he went seven innings and struck out eight batters while allowing just four hits to the Mets so riding the hot hand and good form could be the way to go on this slate.

Others to consider: Matt Boyd vs. Cleveland

 

Want more MLB DFS tools and content? Our MLB Premium package includes our daily DFS Cheat Sheets, Research Station, Optimizer, and access to our Premium Slack Chatrooms where members can chat with our MLB analysts. Check out this recent big win from RotoBaller's RealTalkRaph on DraftKings - join in on the winning!

 

MLB DFS "Bats Worth Paying For"

Willson Contreras – C, CHC @ PIT ($5,200 DK, $2,900 FD)

Contreras looks to be a steal over on FD whereas on DK he is certainly a bat that you will need some salary for but regardless, he is one to really look at paying up for and rostering. Contreras is hitting .348 against lefty pitchers this season and is tied with Kris Bryant for the most home runs off of a lefty pitcher this season with five. Contreras profiles well against Anderson and has great numbers against his cutter as he has an XwOBA of .710 against that specific pitch type.

 

Jake Cronenworth – 1B/2B, SDP @ MIL ($5,400 DK, $3,200 FD)

As shocking as this might be, Cronenworth leads the Padres with a .315 batting average against right-handed pitchers, and all five home runs that he has hit this season have come off of this handedness. Houser has been able to work around right-handed batters but has struggled against lefties as they are hitting .303 against him this season which bodes well for Cronenworth. He has an ISO of .232 and an XwOBA of .420 against this handedness and Houser allows lefties to have an ISO of .208 against him this year.

Kris Bryant – 3B/OF, CHC @ PIT ($5,600 DK, $4,100 FD)

Bryant looks to be one of the best plays on the entire slate and he could be used in all types of formats. In his career at PNC Park, Bryant is hitting .347 with four home runs and when it comes to facing left-handed pitchers there, he is hitting .419 with three home runs in just 52 plate appearances. Bryant has a .337 ISO and a .482 XwOBA against this handedness and profiles well against both Anderson's fastball and cutter as he has a .600+ ISO and a .562 XwoBA against both pitches and Anderson throws them for a combined 57% of the time to right-handed batters.

 

MLB DFS Values

Adam Frazier – 2B/OF, PIT vs. CHC ($3,800 DK, $2,800 FD)

Frazier is usually featured at the top of the order for Pittsburgh and when considering his pricing and how poorly Hendricks has pitched to left-handed pitchers, Frazier looks to be a solid value on both sites. Frazier only has an 11% strikeout rate against this handedness and has been one of the lone bright spots on this Pirates squad as he is hitting .328 on the year while also hitting .331 against right-handed pitchers.

Gregory Polanco – OF, PIT vs. CHC ($2,300 DK, $2,400 FD)

Rostering Polanco is more of a tournament play based on his poor hitting this season but there a few things to like about this matchup against Kyle Hendricks. He has a pretty decent sample size against Hendricks and is hitting .353 against him in over 34 at-bats and Hendricks has struggled against lefty batters all season long as he is allowing them to hit .381 off of him this season with five home runs. All four of Polanco's home runs have come from right-handed pitchers and he is dirt cheap on both sites so he is worth taking a stab at in tournament builds.

Avisail Garcia – OF, MIL vs. SDP ($3,100 DK, $3,100 FD)

Garcia carries a big discount over on DK and would be a very good value play on that site. He is hitting .290 against left-handed pitchers and draws a solid matchup as Weathers has allowed all three of his home runs to come from the right side of the plate. He throws his fastball over 50% of the time to right-handed batters and Garcia has a .222 ISO and a .614 XwOBA against that pitch type.

Also Consider: Hernan Perez vs. Ryan Weathers, Corey Dickerson vs. Spencer Howard 

 

MLB DFS Hitter Stacks

Chicago Cubs vs. Tyler Anderson

The Cubs face off against a lefty in Tyler Anderson and they have some lefty mashers in their lineups. When looking at their potential lineup, the top of the order would be the guys we would want to roster as Bryant, Rizzo, and  Contreras all have a batting average above .300 against lefties this year. Anderson is sporting an ISO of .211 against right-handed batters and has allowed seven home runs in 39 innings pitched to right-handed batters so rostering some of the Cubs righties as well could be a way to target Chicago on this slate.

San Diego Padres vs. Adrian Houser

The Padres have a very good offense, especially when fully healthy, and they look like they could be a top stacking option on this slate. Adrian Houser will be on the bump for the Brewers and he has been tough on right-handed batters but has served it up to lefties as they are batting .303 against him this season. When looking at this Padres stack, guys like Cronenworth, Hosmer, and Profar would be guys to include in your stack while also paying up for Fernando Tatis Jr.

Other stacks: Miami Marlins vs. Spencer Howard, Milwaukee Brewers vs. Ryan Weathers



Download Our Free News & Alerts Mobile App

Like what you see? Download our updated fantasy baseball app for iPhone and Android with 24x7 player news, injury alerts, sleepers, prospects & more. All free!




MLB DFS News and Injury Alerts


More DFS Lineup Picks and Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Daily Stats & Leaders
All Pitcher Matchups
Compare Any Players
Compare Any Players
Rookies & Call-Ups
24x7 News and Alerts

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

REAL-TIME FANTASY NEWS

LaMelo Ball

Won't Suit Up Against Denver
Immanuel Quickley

Questionable for Sunday Afternoon
Deshaun Watson

Expected to Stay With Browns Next Year
Klay Thompson

Downgraded Versus Houston
Alperen Sengün

Alperen Sengun Out Again on Saturday Evening
Tyler Herro

Will Miss Another Game on Saturday
Jimmy Butler III

Out Again on Saturday Night
Draymond Green

Ruled Out Versus Cleveland
Jose A. Ferrer

Mariners Acquire Jose A. Ferrer from the Nationals
Mason Marchment

Expected to Return Saturday
Danila Yurov

Returns From Two-Game Absence Saturday
Jesperi Kotkaniemi

Available Saturday
Harry Ford

Traded to the Nationals
Shane Pinto

to Miss Two Weeks
David Pastrnak

Misses Fifth Consecutive Game Saturday
Andrei Vasilevskiy

Remains Out Saturday
Nikita Kucherov

Out on Saturday
Jayden Reed

Activated Off Injured Reserve, Will Play in Week 14
Omarion Hampton

Activated From IR, Faces Uncertain Workload Monday Night
Cody Bellinger

Drawing Interest From the Phillies
MacKenzie Gore

Will the Nationals Trade MacKenzie Gore?
Justin Herbert

Officially Listed as Questionable for Monday Night Football
Justin Herbert

Chargers "Expecting" Justin Herbert to Play in Week 14
Yves Missi

Trending Toward Game-Time Decision
Khris Middleton

Questionable With Knee Soreness Against Hawks
Noah Clowney

On Track To Suit Up Against Pelicans
De'Anthony Melton

Questionable With Knee Management
Draymond Green

Questionable With Mid-Foot Sprain
Jimmy Butler III

Day-To-Day As Warriors Prepare For Cleveland
Cooper Flagg

College Basketball Daily Fantasy Picks Tonight -Best Lineups and Sleepers for DraftKings (12/6/25)
Mikko Rantanen

Picks Up Three Points Against Sharks
Kyle Connor

Scores in Fourth Consecutive Game
NHL

NHL DFS Picks and Heat Map (Premium Content) - December 6, 2025
Beckett Sennecke

Notches Two Points in Friday's Win
Zach Hyman

NHL DFS Lineup Picks for DraftKings: Goalies, Value Plays, Stacks, and Power Plays Picks (12/6/25)
Ryan Leonard

Suffers Upper-Body Injury Friday
Carter Hart

Day-to-Day With Lower-Body Injury
Brayden Point

Questionable for Saturday
Victor Hedman

Expected to Return Saturday
Byron Buxton

Twins Not Planning to Trade Joe Ryan, Byron Buxton
Patrick Williams

Dalen Terry Available Versus Pacers
Coby White

Returns With Minutes Restriction Friday
Ayo Dosunmu

Out Friday Against Pacers
Zach Collins

Available for Season Debut Friday
Robert Williams III

Donovan Clingan Out, Robert Williams III in for Portland Friday
Evan Mobley

Ready to Play Friday
Kristaps Porzingis

Coming Off the Bench Friday
Ozzy Wiesblatt

to Miss 8-10 Weeks With Upper-Body Injury
Pierre-Olivier Joseph

Out With Illness Friday
Evander Kane

Doubtful for Friday
Conor Garland

Back From Two-Game Absence Friday
Thomas Harley

Could Be an Option Next Week
Rome Odunze

has Fractured Foot, Labeled Week-to-Week
Sauce Gardner

Ruled Out for Sunday
Petr Yan

Looks To Reclaim Bantamweight Belt
Merab Dvalishvili

Set For His Fourth Title Defense
Joshua Van

Can Become The New Flyweight Champion
Aaron Jones Sr.

Cleared to Play in Week 14
Chris Olave

Listed as Questionable for Week 14
Alexandre Pantoja

Set For Fifth Title Defense At UFC 323
Tatsuro Taira

Looks To Win Back-To-Back Fights
Alvin Kamara

Ruled Out for Sunday
Brandon Moreno

Searches For His Third Win In A Row
Rome Odunze

Ruled Out for Week 14
Payton Talbott

A Favorite At UFC 323
Henry Cejudo

Set For His Retirement Fight
Drake London

Ruled Out vs Seattle
Jan Blachowicz

Set To Open Up UFC 323 Main Card
Lamar Jackson

Will Play on Sunday
Bogdan Guskov

Looks To Extend His Win Streak
CFB

Emmett Johnson Leaving Nebraska for 2026 NFL Draft
Dalton Kincaid

to be Questionable for Week 14
Tee Higgins

Clears Concussion Protocol, is a Full-Go for Sunday
CFB

Jam Miller Unlikely to Play in SEC Title Game
CFB

Penn State Expected to Hire Matt Campbell from Iowa State
Mike Evans

Not Quite Ready to Return This Week
Jayden Daniels

Will Start Against Vikings
Lamar Jackson

Returns to Practice, on Track to Play on Sunday
Kyler Murray

Won't Return This Year, Cardinals Non-Committal on his Future
Trey Benson

Out in Week 14; Could he Miss the Rest of the Season?
Marvin Harrison Jr.

Ruled Out for Sunday's Game
CFB

Arkansas Targeting Ron Roberts for Defensive Coordinator Job
Jhostynxon Garcia

Pirates Acquire Jhostynxon Garcia From Red Sox
Cody Bellinger

Yankees Pushing Hard to Re-Sign Cody Bellinger
CFB

Penn State Eyeing Iowa State Coach Matt Campbell For Coaching Vacancy
Alex Bregman

Cubs Have Renewed Interest in Alex Bregman
CFB

Billy Napier Finalizing Deal to Become James Madison's New Head Coach
CFB

Buster Faulkner Set to Become Florida's New Offensive Coordinator
CFB

Joe Sloan Expected to be Kentucky's New Offensive Coordinator
CFB

Lane Kiffin Working to Keep Defensive Coordinator Blake Baker at LSU
CFB

Brian Daboll a Candidate for Penn State Head-Coaching Job?
Kyle Tucker

Visits With Blue Jays
Emilio Pagán

Reds Bring Back Closer Emilio Pagan on Two-Year Deal
Cedric Mullins

Rays Agree on One-Year Deal
Freddy Peralta

Brewers Considering Trading Freddy Peralta
Kyle Schwarber

Reds Serious About Adding Kyle Schwarber in Free Agency?
CFB

Brent Key Signing Five-Year Deal to Remain at Georgia Tech
CFB

Brian Hartline Expected to Land USF Head-Coaching Job
CFB

Collin Klein Expected to be Top Target for Kansas State if Head-Coach Job Opens
CFB

Chris Klieman Considering Stepping Down at Kansas State
CFB

D.J. Durkin Staying at Auburn Under Alex Golesh
CFB

Charlie Weis Jr. Permitted to Coach Ole Miss Offense in College Football Playoff
CFB

Five-Star Quarterback Jared Curtis Flips Commitment From Georgia to Vanderbilt
CFB

Florida Hiring Brad White as Defensive Coordinator
Kyle Schwarber

Giants Have Checked in on Kyle Schwarber
Willson Contreras

Willing to Waive his Full No-Trade Clause?
Edwin Díaz

Mets Still Interested in Re-Signing Edwin Diaz
Devin Williams

Agrees to Three-Year Deal With Mets
Cole Ragans

Red Sox Targeting Cole Ragans in a Trade?
CFB

Kentucky Hires Oregon Offensive Coordinator Will Stein As Head Coach
CFB

Kalani Sitake the Top Target for Penn State Coaching Job
CFB

Josh Heupel Says He's Not a Candidate for Penn State Head Coach Job