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Starts & Sits for Week 6 - All Starting Pitcher Matchups for Fantasy Baseball

Freddy Peralta - Fantasy Baseball Rankings, Draft Sleepers, MLB Injury News

Fantasy baseball starts and sits, advice for all starting pitcher matchups Week 6. Set optimal lineups with Jon's start/sit recommendations.

Five full fantasy weeks in the book and we're rolling right along! Welcome back to RotoBaller! We're getting you ready for everything week six. I'm Jon Anderson back with the starts and sits chart!

The weather has been much friendlier in recent days, which makes my job here a lot easier. Let's hope for more sunshine and games going off as scheduled!

For every week of the fantasy baseball season, we are going to analyze every single projected starting pitcher matchup for fantasy baseball and help you set optimal lineups. Below are the projected starting pitching matchups and starts/sits for Week 6 – May 16-23 – which will be updated as rotations continue to be announced and modified. This column will make continuous adjustments for any postponements or rotation shuffles, reflecting official beat writer speculation for as many unconfirmed rotation slots as possible. Let's set those winning lineups!

Be sure to check all of our fantasy baseball lineup tools and resources:

 

Start/Sit Data Overview

This weekly piece considers the pitcher’s opponents, their outlook against lefties and righties, some ballpark factors, and historical splits. With all of this information, we then provide our start/sit recommendations for each starting pitcher matchup for the approaching week of fantasy baseball.

Each player will be valued with a Start/Sit recommendation, we are also including a "Score" column this year to display the level of confidence in that pick. Scores go from 0-100 in increments of five. The higher, the better! They are also color-coded, as you'll see.

Legend:

  • Proj GS - the number of starts the starter is projected to make in the week's scoring period.
  • Score - A metric of confidence, from 0-100 in increments of five. The higher, the better for the pitcher.

This chart is updated daily as probable starters are constantly changing with game postponements, injuries, and other events.

 

Week 6 Start/Sit Recommendations

Updated start/sit recommendations for week 6 of MLB games:



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POPULAR FANTASY TOOLS

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REAL-TIME FANTASY NEWS

Obi Toppin

Expected to Miss One Month
Andrew Nembhard

to Miss Third Straight Game Wednesday
Bennedict Mathurin

Out Week-to-Week
Jusuf Nurkić

Jusuf Nurkic Iffy for Wednesday
Zaccharie Risacher

Listed as Probable Against Nets
Jalen Johnson

Considered Probable for Wednesday
Dillon Brooks

to Remain Out Wednesday
Jalen Green

Could Make His Suns Debut Wednesday
Anthony Davis

Expected to Play Wednesday
Jaylen Brown

Listed as Probable for Wednesday
Zion Williamson

Uncertain for Wednesday
Alex Caruso

Returns to Thunder Lineup
Gary Trent Jr.

Available Against Knicks
Cole Anthony

Back in Bucks Lineup Tuesday
Miles McBride

Remains Unavailable Tuesday
Guerschon Yabusele

Unavailable Against Bucks
Karl-Anthony Towns

Good to Go Tuesday
Tre Mann

Available Versus Heat
Simone Fontecchio

Cleared for Action
Norman Powell

Out on Tuesday
Chet Holmgren

Won't Play Tuesday
Adam Gaudette

Could Miss Time
John Klingberg

Ready for Action Tuesday
Warren Foegele

to Miss "Some Time"
George Springer

Not in the Lineup for Game 4 of World Series
Brett Pesce

Expected to Be Out for One Month
Jake Neighbours

to Miss at Least Five Weeks
Hampus Lindholm

Expected to Return Tuesday
Jacob Markstrom

Returns to Devils Crease Tuesday
Quinn Hughes

Sits Out Second Consecutive Game
Malik Nabers

Should be Ready for Start of Next Season
Lamar Jackson

Says he's "Ready to Go Now"
Isiah Pacheco

Week-to-Week With MCL Sprain
Tyler Shough

Named Saints' Starting Quarterback
Drake Batherson

Picks Up Three Points in Monday's Win
Sidney Crosby

Becomes Ninth NHL Player With 1,700 Points
Michael Kesselring

Expected to Make Season Debut Tuesday
Shayne Gostisbehere

Could Return Tuesday
K'Andre Miller

Expected to Remain Out Tuesday
Pyotr Kochetkov

Close to Returning
Kareem Hunt

Scores Twice in Monday Night Win Over Washington
George Springer

Pulled Early in Game 3 With Side Injury
Terry McLaurin

Questionable to Return in Week 8 After Aggravating Quad Injury
Baltimore Orioles

Orioles Finalizing Deal to Hire Craig Albernaz as the Next Manager
William Byron

Dominates at Martinsville and Advances to the Championship Round
Kyle Larson

Advances to the Championship Round After Top-Five Finish
Ryan Blaney

Falls Short of the Victory and Title Contention at Martinsville
Chase Elliott

Eliminated From 2025 Title Contention Despite Strong Martinsville Run
William Nylander

Questionable for Tuesday
Rasmus Sandin

to Miss Third Straight Game
Lamar Jackson

Ravens Expect Lamar Jackson to Play on Thursday Night
Dylan Strome

Ruled Out for Tuesday
Brad Marchand

Won't Play on Tuesday
Alexey Toropchenko

Returns to Blues Lineup
Jake Neighbours

Unavailable Versus Penguins
Robert Thomas

Out on Monday
Michael Carter

Cardinals Release Michael Carter on Monday
Carson Wentz

to Undergo Season-Ending Shoulder Surgery
CFB

Behren Morton Will Start Against Kansas State
Nico Collins

Trending Toward a Week 9 Return
Puka Nacua

Expected to Practice Wednesday, Play in Week 9
CFB

Lane Kiffin Says Money Won't Impact his Decision-Making
Tony Pollard

Reportedly Available for Trade
CFB

Arch Manning in Concussion Protocol, Misses Practice Monday
Brian Thomas Jr.

Jaguars Not Planning on Trading Brian Thomas Jr.
Justin Fields

Jets Non-Committal on Justin Fields as the Starter Going Forward
Christopher Bell

Eliminated From Championship 4 After a Too Conservative Season
Joey Logano

Lack of Championship-Caliber Speed Leads to Elimination
Chase Briscoe

Finishes Last at Martinsville
Denny Hamlin

Don't Think Denny Hamlin's Engine Failure Affects his Championship Prospects
Cam Skattebo

Out for the Season With Dislocated Ankle
Ciryl Gane

Fight With Tom Aspinall Ends In No-Contest
Ciryl Gane

Tom Aspinall Vs. Ciryl Gane Ends in No-Contest
Virna Jandiroba

Suffers Unanimous-Decision Loss
Mackenzie Dern

Wins Vacant Strawweight Title
Mario Bautista

Gets Outclassed
Umar Nurmagomedov

Gets Back In The Win Column
Jailton Almeida

Drops Decision
Alexander Volkov

Wins Split Decision At UFC 321
Azamat Murzakanov

Remains Undefeated
Aleksandar Rakic

Suffers First-Round Knockout
Tucker Kraft

Dominates With 143 Yards, Two Touchdowns on Sunday Night
Troy Franklin

Explodes for Two Touchdowns Against Cowboys
J.K. Dobbins

Breaks 100 Yards Again but Doesn't Find the End Zone
Bo Nix

has a Season-Best Four Passing Touchdowns
Jalen Hurts

Matches Career High With Four Touchdown Passes in Week 8
RJ Harvey

R.J. Harvey Breaks Out With Three Touchdowns in Week 8
Chris Buescher

Is Chris Buescher A Playable DFS option for Martinsville?
Ryan Preece

is an Intriguing DFS Option For Martinsville
Daniel Suarez

May be Worth Rostering in DFS for Martinsville
Austin Dillon

Is Austin Dillon Worth Rostering in DFS for Martinsville This week?
Christopher Bell

Kyle Larson Should Advance to Championship 4
Joey Logano

Don't Expect Joey Logano to Significantly Contend for Championship 4
William Byron

A DFS Must-Start Due to Lap-Leader Points
Ross Chastain

Hail Melon Nostalgia Masks Ross Chastain's Martinsville Mediocrity
Josh Berry

a Top Contender for DFS Place-Differential Points
Brad Keselowski

an Intriguing Martinsville Option
Shane Van Gisbergen

Now Competent on Ovals, but Don't Start Him Here
Kyle Busch

Qualifies Well but Probably Won't Have Staying Power
Carson Hocevar

Lack of Finesse Makes Him a Risky Martinsville Pick
Bryce Harper

Phillies Aren't Planning to Trade Bryce Harper
Bo Bichette

Starting at Second, Batting Cleanup in Game 1 of World Series
Bo Bichette

Makes World Series Roster
Ciryl Gane

Scheduled For A Title Fight
Tom Aspinall

Set for First Official Title Defense
Mackenzie Dern

Can Become The New Strawweight Champion
Virna Jandiroba

Set For UFC 321 Co-Main Event
Mario Bautista

Aims To Extend His Win Streak
MMA

Umar Numagomedov A Favorite At UFC 321
Jailton Almeida

Hopes To Get A Title Shot With A Win
Alexander Volkov

Looks To Get Back In The Win Column
Azamat Murzakanov

Looks To Remain Undefeated
Aleksandar Rakic

In Dire Need Of Victory
CFB

Texas Tech QB Will Hammond Will Start vs. Oklahoma State Saturday
CFB

Kansas State RB Dylan Edwards Out For Sunflower Showdown
CFB

Arizona State WR Jordyn Tyson Will Not Play In Week 9
Zack Wheeler

Could be Ready for Opening Day in 2026
William Contreras

Could Need Finger Surgery

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