Best Week 6 QB Streamers - Fantasy Football Quaterbacks to Pickup and Start

The top Week 6 quarterback streamers, fantasy football pickups and QB starts for 2025. Target these fantasy QB streaming options with strong Week 6 matchups.

Picking the right quarterbacks to start each week could be the difference between a win and a loss. After all, quarterbacks score more points than any other position week-to-week. With several quarterbacks currently dealing with injuries, you could be looking to stream a quarterback in this pivotal Week 6.

This article will feature five of the top quarterback streaming options for Week 6. All five of these quarterbacks are rostered in under 60% of ESPN leagues and could turn out to be solid fantasy options this week.

So, which quarterbacks should you be streaming in Week 6? Let's dive in and find out.

Top Quarterback Streamers for Week 6

Only players rostered in fewer than 60% of fantasy football leagues are considered potential streamers.

Trevor Lawrence (JAC) vs. Seattle Seahawks
35% Rostered

Trevor Lawrence is coming off one of the best fantasy games of his career, scoring 27.2 fantasy points in last week's win over the Chiefs. Although Lawrence has been an inconsistent QB option through the first five weeks, he could be a solid streaming option in Week 6 against the Seattle Seahawks.

TREVOR LAWRENCE UNREAL 😱

Go-ahead TD in the final seconds ‼️ pic.twitter.com/qZ75CwU4tZ

— ESPN (@espn) October 7, 2025

Seattle has allowed multiple passing touchdowns in back-to-back games and just let Baker Mayfield throw for 379 yards and two touchdowns last week. Given that the Seahawks have given up the sixth-most passing yards per game this season, Lawrence is worth a look in some one-quarterback leagues.

Sam Darnold (SEA) at Jacksonville Jaguars
22% Rostered

Sam Darnold has shown some nice things for fantasy managers over the last few weeks. He has scored over 16 fantasy points in four straight games and just scored 28.6 fantasy points in last week's shootout against the Buccaneers. In that game, Darnold threw for a season-high 341 yards and four touchdowns.

JAXON
SMITH
NJIGBA

TBvsSEA on CBS/Paramount+https://t.co/HkKw7uXVnt pic.twitter.com/GL08Ze6J4N

— NFL (@NFL) October 5, 2025

Now, he'll have a semi-solid matchup against the Jaguars in Week 6. The Jaguars have allowed over 19 fantasy points to a QB in three of the past four games. Considering Jacksonville's secondary has also let up a 300-yard passer in back-to-back weeks, Darnold is worth a look in some one-quarterback leagues. He is ranked as the QB17 on our rankings this week.

Bryce Young (CAR) vs. Dallas Cowboys
18% Rostered

No quarterback has a better matchup this week than Bryce Young. Young will be going up against a Cowboys secondary that ranks 32nd in fantasy points allowed, 32nd in pass yards allowed, 30th in pass touchdowns allowed, and 27th in rush yards allowed to opposing QBs. That makes Young a strong streaming option for Week 6.

The Cowboys have allowed over 24 fantasy points to every QB they have faced this year, which is great news for Young's fantasy potential this week. Even though the Panthers signal-caller has been held to under 13 fantasy points in four of five contests, it's hard to pivot away from a QB who is playing a bottom-five secondary this week.

Mac Jones (SF) @ Tampa Bay Buccaneers
4% Rostered

Mac Jones will be making his fourth start with the 49ers this year. In his first three starts, Jones has looked like a viable QB1 option. He is averaging 19.4 fantasy points across those three contests, which have included two top-10 QB finishes during this span. Last week, the 27-year-old threw for a season-high 342 yards and two touchdowns en route to a QB10 fantasy finish.

Mac Jones to Jauan Jennings for the 42-yard TD!

SFvsNO on FOX/FOX Onehttps://t.co/HkKw7uXVnt pic.twitter.com/oRKIHFajpv

— NFL (@NFL) September 14, 2025

As a result, Jones is worth starting as a QB1 in some 12-plus team leagues. The Buccaneers have allowed a top-12 fantasy QB in four of five games this season, and Darnold just tormented this secondary for 341 yards and four touchdowns last week. The 49ers signal-caller comes in as the QB19 in our Week 6 rankings.

Tua Tagovailoa (MIA) vs. Los Angeles Chargers
22% Rostered

Tua Tagovailoa hasn't really been a consistent QB1 option for fantasy managers this year. He has finished outside the top-16 at the QB position in four of five games. However, Tagovailoa is coming off his best fantasy finish of the season last week, throwing for 256 yards and three touchdowns en route to a QB9 finish.

Therefore, Tagovailoa is worth a look in some deeper one-quarterback leagues this week. The gun-slinging lefty has scored above 19 fantasy points in two of his past four games, and the Chargers haven't exactly played well defensively in recent weeks. Given that Los Angeles has allowed over 17 fantasy points to three different QBs this year, the Dolphins QB could be worth starting in 18-plus team leagues.

Read more Quarterback news and updates for Week 6

Week 6 Quarterback Rankings for Fantasy Football

Bookmark our PPR rankings, Half-PPR rankings, and standard (non-PPR) rankings 

Who Should I Start Tool

You can also see the Who Should I Start tool here.

Week 5 Quarterback Decisions. Today's focus is on specific QBs - Trevor Lawrence, Sam Darnold, Tua Tagovailoa, Mac Jones, Bryce Young. These are some of the most common searches for fantasy football lineups in Week 5.

Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player's name. In the second box, search for the second player's name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.

Improvements For Who Should I Start? You may have noticed our Who Should I Start? tool has gotten an overhaul. We've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, stats, projections, strength of schedule, players' news, and enhanced search results with data to compare with a slick new interface. We hope you enjoy!

How It Works. Each week, our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.

Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do is to select the scoring format. There are three small radio buttons (small circles), so click on the scoring format you prefer. The results may vary based on the scoring format you select.

Popular Week 5 Searches. Curious to see some tough lineup decisions for Week 5 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.

Popular Week 6 Searches - Start/Sit Player Comparisons

Below are some popular searches and comparisons from our Who To Start tool for Week 6 for Trevor Lawrence, Sam Darnold, Tua Tagovailoa, Mac Jones, Bryce Young:

More Fantasy Football Analysis