September 14, 2025
Detroit Lions safety Kerby Joseph (knee) is active for Sunday's Week 2 contest against the Chicago Bears. He had been listed as questionable after popping up on Friday's injury report as a limited participant. The 24-year-old played every defensive snap last week but registered just one tackle. He'll look to make a bigger impact this week, and we expect him to return to his 2024 form soon. Last season, he intercepted nine passes and was named a First-Team All-Pro.
--Andersen PickardSource: Detroit Lions
September 14, 2025
Detroit Lions running back
Sione Vaki (hamstring) is officially inactive for Sunday's Week 2 contest against the Chicago Bears. He was limited in practice this week but was not expected to play after the Lions listed him as doubtful. The 24-year-old played in 16 games last year, totaling 51 scrimmage yards, but has not yet stepped on the field in his second pro campaign.
Craig Reynolds will continue to operate as the Lions' No. 3 running back behind
Jahmyr Gibbs and
David Montgomery.
--Andersen PickardSource: Detroit Lions
September 14, 2025
Detroit Lions left tackle Taylor Decker (shoulder) is active for Sunday's Week 2 contest against the Chicago Bears. Decker had been listed as questionable, and there was some concern about his availability after he didn't practice this past week. However, in the end, the veteran lineman is healthy enough to suit up. His presence will be quite impactful for the Lions' offensive line as they look to protect
Jared Goff,
Jahmyr Gibbs, and
David Montgomery on Sunday. Decker played all 67 snaps last week, allowing one sack.
--Andersen PickardSource: Detroit Lions
September 14, 2025
Cleveland Browns rookie running back
Quinshon Judkins is slated to see 10-15 snaps in his NFL debut on Sunday. While Judkins was able to practice with the team leading up to this contest against the Ravens, it appears the Browns will closely monitor his workload in this game. Judkins was unable to play in the preseason and participate in training camp as he was facing domestic violence charges. While his prosecutors eventually dropped their charges, he could still face a suspension from the league. However, for now, Judkins should remain a key part of the Cleveland backfield. In Week 1, the Browns relied on fellow rookie
Dylan Sampson and veteran
Jerome Ford. With Judkins now returning, managers should expect Sampson to remain the lead option, with Judkins seeing a few opportunities in short-yardage situations. As a result, Sampson still holds flex appeal while Judkins is a touchdown-dependent high-risk RB3.
--Andy SmithSource: Ian Rapoport
September 14, 2025
New Orleans Saints right tackle Taliese Fuaga (knee) is officially active for Sunday's Week 2 contest against the San Francisco 49ers. He had been listed as questionable but was trending in the right direction prior to gameday. Fuaga has started all 18 games since being drafted, allowing seven sacks and 43 pressures through 1,116 offensive snaps. He'll look to protect
Spencer Rattler and
Alvin Kamara from the impact of a strong 49ers defense.
--Andersen PickardSource: New Orleans Saints
September 14, 2025
San Francisco 49ers wide receiver
Jauan Jennings (shoulder) is officially active for Week 2 against the New Orleans Saints. Jennings had been listed as questionable, but there was increased optimism about his status heading into gameday. The shoulder issue limited Jennings to just 66 percent of the offensive snaps last Sunday as he caught two of five targets for 16 yards. This week, he'll be playing with a quarterback downgrade as
Mac Jones steps in for the injured
Brock Purdy (shoulder). Jones still has a solid arm, and a favorable matchup against the Saints bodes well for Jennings. Plus, the 49ers will also be without
George Kittle (hamstring), creating several vacated targets that could go Jennings' way. He's a solid WR3/flex option this week.
--Andersen PickardSource: Matt Maiocco
September 14, 2025
Los Angeles Rams tight end
Colby Parkinson (shoulder) is officially inactive for Sunday's Week 2 contest against the Tennessee Titans. He had been listed as doubtful after missing all three practices leading up to this weekend's game. Parkinson is working his way back from an AC joint sprain that he suffered last Sunday against the Houston Texans. Parkinson was actually able to finish last week's game after receiving medical attention, but evidently, the Rams aren't going to send him onto the field for Week 2.
Terrance Ferguson is active for his NFL debut and will assist in filling Parkinson's void alongside a tight end committee that also features
Tyler Higbee and
Davis Allen. None of these Rams tight ends can be trusted in fantasy football, but Ferguson is an intriguing stash in dynasty leagues.
--Andersen PickardSource: Gary Klein
September 14, 2025
According to Ian Rapoport of the NFL Network, Kansas City Chiefs wide receiver
Xavier Worthy (shoulder) is hoping to return next week when the Chiefs face the New York Giants. Rapoport noted that if Worthy can suit up, he would be playing with a torn labrum. However, the star wideout intends to wear a harness if he were to play. This week, Worthy was able to return to practice, which is an excellent sign that he is nearing a return. The second-year wideout suffered this injury during the opening possession of the first game of the season against the Chargers. As a rookie, Worthy flashed big-play upside in the Kansas City offense, totaling nine touchdowns with over 700 yards from scrimmage. This weekend,
Marquise Brown and
JuJu Smith-Schuster figure to lead the passing attack.
--Andy SmithSource: Ian Rapoport
September 14, 2025
The Baltimore Ravens planned to select quarterback
Shedeur Sanders with their fifth-round pick in the 2025 NFL Draft, but once the quarterback heard about the Ravens' plans, he nixed the pick. According to ESPN's Adam Schefter, Sanders "let it be known to Baltimore that he didn't want to be on a roster with
Lamar Jackson." The Ravens pivoted to offensive lineman Carson Vinson with the No. 141 pick, and Sanders landed with the Browns three selections later. Schefter's report seems to indicate that Sanders didn't have anything against Jackson in particular, and his concern was more about being stuck behind any quarterback who wasn't going to relinquish their starting role anytime soon. He likely would have had a similar reaction to being drafted by any team with an established starter, which is why Cleveland ended up being an ideal landing spot for him. While
Joe Flacco is the Browns' starter for the time being, Sanders has a chance to start games later this season if Flacco struggles or Cleveland's playoff hopes are destroyed.
--Andersen PickardSource: Adam Schefter
September 14, 2025
The Los Angeles Rams want to feature veteran wide receiver
Davante Adams more often during Sunday's Week 2 contest against the Tennessee Titans. "Sean McVay was pleased with what the Rams accomplished in the passing game in Week 1, but getting Davante Adams a bit more involved will be a goal against [the] Titans," writes Gary Klein of the Los Angeles Times. Adams finished his Rams debut with eight targets, four catches, and 51 yards. It was a fine showing for the veteran receiver, but certainly not on par with his full potential. Speaking with Klein, Adams said that he's trying to contribute however he can, and the number of targets he receives is not his concern. He noted that he thinks his and
Puka Nacua's roles will vary week by week. If one player is having a big game, they'll command more attention from the defense, leaving the other receiver with opportunities to make plays happen in one-on-one coverage. As it stands, both players are strong WR2 options with WR1 upside.
--Andersen PickardSource: Gary Klein
September 14, 2025
Green Bay Packers wide receiver
Jayden Reed (collarbone) is looking at a multiple-month absence. According to Ian Rapoport, Reed was given a six-to-eight-week timetable to return. Reed suffered a broken collarbone during the Week 2 win over the Washington Commanders on Thursday night. This timeframe means that Reed is likely out until some point in November. Fantasy managers can go ahead and place Reed on their Injured Reserve if they haven't already. The good news is that Reed isn't going to be done for the season. His absence should mean increased roles for
Romeo Doubs,
Matthew Golden,
Dontayvion Wicks, and
Tucker Kraft.
--Andy WebbSource: Ian Rapoport
September 14, 2025
New Orleans Saints offensive tackle Taliese Fuaga (knee) remains listed as questionable heading into the Week 2 matchup against the San Francisco 49ers. Despite that, Nick Underhill reports that Fuaga is expected to suit up for this contest. Fuaga missed Wednesday's practice, but was able to get in two limited sessions to finish the week. The absence of Fuaga would certainly hurt the blindside of
Spencer Rattler. Asim Richards would likely be asked to take over if Fuaga is unable to go.
--Andy WebbSource: Nick Underhill
September 14, 2025
San Francisco 49ers offensive tackle Trent Williams (knee) remains listed as questionable ahead of the Week 2 matchup against the New Orleans Saints. Williams made an early exit from the season opener due to a knee injury. He was able to return to the contest, but appears to still be dealing with the knee issue. The absence of Williams would be a huge loss to the 49ers' offensive line. It would be a major downgrade for the blind side of
Mac Jones. The plan is for Williams to test his knee pre-game before making a final decision. If he sits, Spencer Burford would be in line to take over at left tackle.
--Andy WebbSource: Adam Schefter
September 14, 2025
According to Adam Schefter, San Francisco 49ers wide receiver
Jauan Jennings (shoulder) is expected to suit up for the Week 2 matchup against the New Orleans Saints. Jennings is currently listed as questionable, but it sounds like he's trending towards suiting up. He was tagged as a game-time decision on Saturday, but it sounds like he has improved overnight. The 49ers could certainly use Jennings on the field with
George Kittle (hamstring) sidelined. Jennings will probably take a hit in value with
Brock Purdy (toe) out. However, the 49ers are so limited on options that Jennings should remain a viable fantasy option even with
Mac Jones under center.
--Andy WebbSource: Adam Schefter
September 14, 2025
According to Adam Schefter, San Francisco 49ers quarterback
Brock Purdy (toe) is unlikely to play in Week 3 against the Arizona Cardinals. Purdy will be absent in Week 2, and it sounds like he'll miss multiple games due to a turf-toe issue. There's a chance that Purdy misses as many as five games from this injury. Backup
Mac Jones will be under center in Week 2, and it sounds like he'll be drawing multiple starts. Jones doesn't offer a ton of upside, but he has value in superflex fantasy formats for those desperate at the QB position already. It sounds like the 49ers are going to need to lean on him for at least two games.
--Andy WebbSource: Adam Schefter
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