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Tennessee Titans running back Derrick Henry is matchup proof and gets to face an Arizona Cardinals defense that has allowed 125.5 rushing yards per game. He is a surefire RB1 and will begin the 2021 season against a defense that surrendered the 11th most fantasy points to opposing running backs. The 27-year-old had 2,027 rushing yards on 378 rushing attempts and 17 touchdowns in 2020. He is set for another massive workload and will look to make it back-to-back 2,000-yard seasons. Henry should produce elite numbers and is an elite option in Week 1.--Brad Camara - RotoBaller
Source: Pro Football Reference
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