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Should I start Khalil Shakir, Jakobi Meyers, Rashid Shaheed for Week 6? Fantasy football start 'em, sit 'em picks and recommendations for the 2025 NFL season.
For fantasy managers, nothing can be more frustrating than deciding whether or not to start a wide receiver in that gray zone. You know, the type of WR that has all the talent to make you want to start them, but is also inconsistent enough to make you hesitate.
Week 6 brings more difficult lineup decisions, especially with dreaded bye weeks and injuries taking a toll. Khalil Shakir, Jakobi Meyers, and Rashid Shaheed have the potential for big games, but figuring out when to trust them becomes the tricky part.
Let's look at the Week 6 matchups to see which wide receivers deserve a starting nod this week and who is best left sitting on your bench.
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Should I Start Khalil Shakir for Fantasy Football?
Steady, but not top-tier, is the perfect way to describe Shakir this season. He brought in six passes on nine targets for 45 yards in the Bills' Week 5 loss to the Patriots. The receiver matched a season high in targets, but he wasn't able to do much with them.
Even so, Shakir remains an integral piece in the Buffalo offense. He leads the team in receptions at 22 and sits second in receiving yards (235) and touchdowns (two). The Boise State alum is gaining opportunities, but Buffalo likes to rotate their receivers, capping his ceiling.
I asked Khalil Shakir his secret for maintaining his balance through contact and yards after the catch.
"Just letting your body flow... Maybe I close my eyes sometimes. You open your eyes and it's like 'Oh snap'"#BillsMafia @BuffaloPlus pic.twitter.com/mlswwQ84Hf
— Dan Fetes (@danfetes) October 1, 2025
This week's matchup with the Falcons won't do Shakir many favors. Atlanta has allowed the second-fewest receiving yards to opposing wideouts at 494 total, conceding the sixth-fewest fantasy points per contest to the position. Add in that cornerback A.J. Terrell Jr. is back, and it's a recipe for disaster for the receiver.
If you're struggling with depth or dealing with the bye week, Shakir is a decent flex in deeper PPR leagues (if you need just eight to 10 solid points). His ceiling is limited unless the game script requires Josh Allen to toss 40-plus passes. In shallow leagues, you're probably best off leaving him on the bench.
Should I Start Jakobi Meyers for Fantasy Football?
After starting the season with a bang, Meyers has come back to earth quickly. He opened the season with back-to-back double-digit PPR games (17.7 and 12.8 points) but hasn't achieved one since. In Week 5, with Brock Bowers injured, the WR posted just 32 yards on four receptions as the Raiders were trampled by Indianapolis, 40-6.
Quarterback Geno Smith has hindered Meyers plenty this season. He's tossed a league-high nine interceptions to just six touchdowns so far and has not been on the same page as his offensive weapons. Meyers' targets have dropped because of this, with 26 over the first three matchups to just 13 combined in the last two.
Jakobi Meyers with a great whip route creating separation. Sell inside route, pivot outside.#RaiderNation pic.twitter.com/nZfVzyB9zY
— Ryan Holmes (@Rholm22) September 30, 2025
This week's battle with the Titans gives managers reason for optimism. Tennessee has given up the fifth-most receiving yards to opposing wideouts at 805. Additionally, they rank eighth in fantasy points given up to the position and have allowed four touchdowns to receivers (one per contest except last week).
The volume hasn't been outstanding lately, but with Meyers still seeing over 90% of snaps most days, he's still a major focal point of the offense. Against a beatable Titans secondary, he makes for a stable WR3/Flex play in Week 6. Meyers is safer than Shakir because the matchup is a softer one, but his fantasy day will come down to whether Smith can sustain drives.
Should I Start Rashid Shaheed for Fantasy Football?
Few players can break out with huge fantasy numbers off one play, but Shaheed is a player who definitely can. He exploded in Week 5, tallying 114 yards and a score on just four catches. That touchdown went for 87 yards, registering a speed of 21.72 mph (per NFL Next Gen Stats), the fifth-fastest play of the season.
His big-play speed makes him a dangerous fantasy asset. Through five games, Shaheed has registered 22 catches for 288 yards and two scores on 30 targets, ranking third on the Saints in looks behind fellow wideout Chris Olave and tight end Juwan Johnson. Although he isn't heavily targeted, he still gets the most out of what he's given.
Rashid Shaheed was born to make big plays pic.twitter.com/d0vRXYbbdy
— New Orleans Saints (@Saints) October 8, 2025
This week's matchup with New England sets up nicely for the receiver. The Patriots have given up the seventh-most receiving yards and nine touchdowns to WRs this year. Defensive starters like Keion White and Jaylinn Hawkins are banged up, meaning Shaheed could rip off another big play.
The Saints' offense has trusted Spencer Rattler more lately, which only brightens Shaheed's outlook. He has a safer floor than many others in WR2/WR3 or Flex consideration for the week. Shaheed's a start, especially if you're filling injury or bye week gaps.
Who Should I Start Tool
Not sure who to start? Check out the Who Should I Start tool:
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Who Should I Start? Who Should I Sit? Some common Week 6 fantasy football lineup decisions are regarding players like Garrett Wilson, DJ Moore, and Marvin Harrison Jr. But not to worry, we are here to help make these decisions and build winning lineups in Week 6. Set your optimal fantasy football lineups for Week 6 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
Week 6 Player Decisions. Today's focus is on specific players - Garrett Wilson, DJ Moore, and Marvin Harrison. These are some of the most common searches for fantasy football lineups in Week 6.
Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player's name. In the second box, search for the second player's name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.
Improvements For Who Should I Start? You may have noticed, our Who Should I Start? tool has gotten an overhaul. We've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, enhanced search results with data to compare, and a slick new interface. We hope you enjoy!
How It Works. Each week, our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.
Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do is to select the scoring format. There are three small radio buttons (small circles), so click on the scoring format you prefer. The results may vary based on the scoring format you select.
Popular Week 6 Searches. Curious to see some tough lineup decisions for Week 6 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 6 Searches - Start/Sit Player Comparisons
Below are some popular Week 6 searches and comparisons from our 'Who To Start' tool for Garrett Wilson, DJ Moore, Marvin Harrison Jr., compared to others:
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