NFL DFS Week 15 Picks (Main Slate): Top DraftKings Plays for Daily Fantasy Include Dak Prescott, Christian McCaffrey, Puka Nacua

Joe Nicely's DraftKings NFL DFS picks and lineup sleepers for the Week 15 (December 2023) Main Slate. His top daily fantasy football lineups to target for DraftKings NFL DFS contests.

Hello, RotoBallers, and thanks for joining me to talk NFL DFS. With many season-long leagues getting their playoffs underway this week, I understand that some of you might be looking for a way to stay in action for Week 15. You've come to the right place, as the DFS party don't stop until the Super Bowl is concluded!

This week's DraftKings lineup recommendations are based on matchups, projected DK points and ownership, overall upside/talent levels, and opportunity, as well as factors such as Vegas odds, home-field advantage, and more. There are quite a few great plays available on DK for Week 15.

Also, be sure to check out our weekly FanDuel DFS lineup picks and lots of other great NFL DFS articles and NFL DFS tools to help you win big! Good luck with your DraftKings DFS lineups -- let's dominate this slate together!

• 2025 fantasy football rankings
• Running back (RB) fantasy football rankings
• Wide receiver (WR) fantasy football rankings
• Tight end (TE) fantasy football rankings
• Quarterback (QB) fantasy football rankings
• FLEX fantasy football rankings
• Defense (D/ST) fantasy football rankings
• Kicker (K) fantasy football rankings
• Dynasty fantasy football rankings

DraftKings Quarterbacks - Week 15 DFS Picks

Dak Prescott - DAL @ BUF ($8,000)

I'll have exposure to both QBs in this clash of the titans, but since Dak Prescott comes in a bit cheaper than Josh Allen, we'll focus on him for the purposes of this article. Prescott has simply been the best quarterback in the NFL over the past two months. Since the team's bye in Week 7, Dak and this Dallas offense are averaging an eye-popping 38 points per game while playing at the league's third-fastest pace over the past month.

If you take Dak Prescott’s game averages during his 8 game hot streak and stretched it out over a 17 game season, here’s what his numbers would look like:

5,193 Passing Yards
48 Passing TDs
4 INTs
297 Rushing Yards
4 Rushing TDs

Dak Prescott is playing at a historic level. pic.twitter.com/MXgvbBcmx9

— B Young (@TDCeeDee) December 15, 2023

As for Prescott specifically, he's now topped 28 DraftKings points in five of seven since coming out of Dallas' aforementioned bye week and has put himself squarely in the MVP conversation. This matchup against Buffalo is a middling one, but certainly not impossible for the red-hot 'Boys QB. The Bills have allowed 17 passing TDs this season, while relinquishing nearly 3,000 passing yards.

Matthew Stafford - WAS @ LAR ($6,000)

The veteran's stats don't do justice to how well he's playing in 2023. However, Stafford has been making headway with box scores lately, as he's now topped 23 DraftKings points in three straight. He draws perhaps the most desirable QB matchup in the NFL against the Washington Commanders in Week 15 on the heels of a vintage Stafford performance against Baltimore last week, an outing where he threw for 294 yards and three TDs.

The Rams signal-caller has tossed 10 TDs to just one INT since Week 12. Wielding a hot hand, Stafford should torch a Commanders secondary that allowed the most passing TDs (30) in the NFL this season and stands dead last in the league in yards per attempt (8.06) relinquished to opposing QBs.

MORE TOP QB PLAYS: Josh Allen ($8,200); Sam Howell ($6,300)

DraftKings Running Backs - Week 15 DFS Picks

Christian McCaffrey - SF @ ARI ($9,300)

McCaffrey feels a little like low-hanging fruit for this article. I mean, when isn't he a good play, right? With that sentiment in mind, I try to save CMC words for the truly special NUCLEAR spots, and here we are with McCaffrey set to take on the Cardinals in Week 15.

The superstar Niners back shredded this Arizona defense for 177 all-purpose yards and four TDs when these teams met back in Week 4, an outburst that was good for 51.7 DraftKings points! While McCaffrey might not drop another 50 burger this week, it's at least in his range of outcomes against a Cardinals defense that's allowed the NFL's second-most rushing yards (1,567) this season.

Ezekiel Elliott - KC @ NE ($5,800)

I didn't have "writing up Zeke" on my 2023 Bingo card, but here we are. The Cowboys castoff has solidified a role for himself in the New England backfield this season, and with Rhamondre Stevenson set to miss his second consecutive game in Week 15, Elliott will once again serve as the Pats' featured back against the Chiefs.

EzekielElliott feeling good at the end of TNFpic.twitter.com/fjBGB4x30B

— Live Sports (@DailySportsFree) December 8, 2023

In Stevenson's absence last week against Pittsburgh, the veteran saw workhorse -- serious workhorse -- usage. Elliott was on the field for 91% of New England's offensive snaps in Week 14 and earned a hard-to-fathom 30 total opportunities which resulted in 140 all-purpose yards and a TD for the 28-year-old. He should continue to stay busy against a Kansas City defense that's allowed the league's seventh-most DraftKings points to the RB position over the past month.

MORE TOP RB PLAYS: Kyren Williams ($7,500); Rachaad White ($7,000)

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DraftKings Wide Receivers - Week 15 DFS Picks

Puka Nacua - WAS @ LAR ($7,300)

As mentioned when highlighting Matthew Stafford in this week's article, this leaky Commanders secondary is one we want to attack by any means necessary. Washington ranks dead last in the NFL in receiving yards (2,580) and yards per target (10.12) allowed to opposing WRs, while coughing up the second-most TDs (20) to the position in the league this year.

Puka Nacua: The highest-graded rookie in the NFL pic.twitter.com/imHq6AvBPI

— PFF (@PFF) December 13, 2023

The Rams rookie sensation is well equipped to take advantage of the juicy matchup. Nacua's first pro campaign has been a beauty. He currently ranks sixth in the NFL in receiving yards (1,183) while averaging a rock-solid 18.3 DraftKings points per game. He stands just 361 yards short of the all-time rookie receiving record with four games left to go. Even with Cooper Kupp back in the Rams lineup, Nacua has target counts of 8/7/8/7 over L.A.'s last four games.

Jayden Reed - TB @ GB ($4,900)

With Green Bay's WR1 Christian Watson looking extremely doubtful for Week 15 as of this writing, rookie wideout Jayden Reed should once again be in for a featured role against the Bucs. With Watson sidelined last week, Reed made plays both through the air and on the ground, amassing 65 total yards and a TD on 10 targets and four rushing attempts.

In a matchup against Tampa Bay, Reed will have the opportunity to exploit one of the league's most extreme pass-funnel units. While being one of the NFL's stoutest defenses against the run, the Bucs have bled points through the air, allowing the league's second-most receiving yards to opposing wideouts.

MORE TOP WR PLAYS: CeeDee Lamb ($9,200); DeAndre Hopkins ($6,200); Wan'Dale Robinson ($3,700)

DraftKings Tight Ends - Week 15 DFS Picks

Trey McBride - SF @ ARI ($5,200)

Yes, the matchup against San Francisco is a brutal one for Trey McBride, but talent and volume can overcome a lot. McBride is showing that he has both in spades this year. The former second-round pick out of Colorado State has blossomed in his second professional season.

McBride heads into Week 15 ranked sixth among tight ends with 610 receiving yards, despite being planted behind Zach Ertz on the depth chart for the first month of the season. He's quickly formed a nice rapport with Arizona QB Kyler Murray and has been targeted an eye-opening 34 times in Murray's four games under center this season. McBride should once again be heavily targeted in this one, as Arizona will likely be playing from behind most of the day.

David Njoku - CHI @ CLE ($4,700)

Despite the Browns rotating cast at the QB position this season, Njoku has been low-key productive in 2023. He comes into this week's matchup against Chicago averaging a healthy 10.2 yards per reception on the year and 9.4 targets per game over Cleveland's last five.

ELITE Joe Flacco TO DAVID NJOKU FOR THE SECOND TIME TODAY ‼️ #Browns pic.twitter.com/xh6BUmvT0V

— DraftKings Sportsbook (@DKSportsbook) December 10, 2023

Joe Flacco looked liked the skeleton key that could fully unlock Njoku last week. The duo hooked up six times for 91 yards and two TDs against Jacksonville. With Flacco still at the helm, Njoku should continue to thrive in Week 15 against a Bears squad that's allowing a sky-high 78.3% catch rate to opposing tight ends.

MORE TOP TE PLAYS: George Kittle ($5,800); Cole Kmet ($4,500)

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