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Week 6 NFL - Fantasy Score DFS Prop Picks for PrizePicks

mark andrews fantasy football rankings NFL DFS lineup picks

Kipp Heisterman presents his Fantasy Score NFL DFS prop picks on PrizePicks for Week 6 of the NFL Season. Use his NFL prop picks recommendations to win money on PrizePicks.

Hello everybody and welcome! The 2021 NFL season is finally underway and that means our new friends over at PrizePicks have a TON of great props we can look to take advantage of. PrizePicks is a great DFS props site where you can choose to select plays in terms of fantasy points or single stats. The goal is to build a 2-player, 3-player, 4-player, or 5-player entry and then select whether or not you want to play for the power play or the flex play. On the power play, you will need to be correct on each of your selections to win, and on the flex play, you will have a little more wiggle room for a chance to win some money back.

Our partners at PrizePicks offer some of the best and easiest to win NFL DFS games in the industry. There are no large-field tournaments filled with sharks where you have to get lucky just to place. At PrizePicks, you're not playing against other people, you're just playing against the projections, and the guys at PrizePicks have worked hard to give you really attractive opportunities to make some money. With promo code 'BALLER' you can get a 100% match on your deposit up to $100.

PrizePicks has two types of games. The first type of game is known as Fantasy Score, which consists of selecting various players and trying to determine if they will go over or under their projected fantasy points in a game. The second game is known as Single Stat. For NFL, Single Stat consists of quarterback passing yards, running back rushing yards, and wide receiver receiving yards in which you determine if the player in question will go over or under their projected total. You can mix and match players from each type of game in your entry or select all of your plays from the same type of game. Once you have selected your players and props, you can choose the aforementioned flex play or power play option. Today, we will look at some fantasy score totals for the Week 6 of the NFL season.

Be sure to check all of our fantasy football rankings for 2025:

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Fantasy Score NFL Totals

Before diving into some solid fantasy score totals this week, we must first cover the PrizePicks scoring format. The format is PPR, which stands for a point per reception, meaning every reception is worth one point. Rushing and receiving touchdowns are worth six points and passing touchdowns are worth four points. Each rushing or receiving yard is worth .1, meaning every 10 yards of either is worth one point. Quarterback passing yards are worth .04, which means every 25 passing yards are worth one point. If you ever have questions, you can always click the "scoring chart" option above the player selections for each contest. Now let's get to some solid fantasy score props for this week.

Darrell Henderson over 16.0 fantasy score - Henderson and the Rams will enter this game against the New York Giants as close to double-digit favorites, which should add volume to their rushing attack. Over the previous four weeks, the Giants have allowed an average of 30 fantasy points per game to running backs, which is ranked fifth-worst in the league. They have given up 476 rushing yards and 264 receiving yards to backs over this span. Henderson has averaged 15 carries per game and has also been involved in the passing game as he has averaged 2.5 targets per game. He should be in line for a solid workload in this one.

Mecole Hardman over 10.0 fantasy score - MeCole Hardman gets a solid matchup against a Washington Football Team that has allowed wide receivers to put up 747 receiving yards over the previous four weeks, which is ranked ninth-worst in the league. They have also allowed six receiving touchdowns over that span, which is ranked fourth-worst in the league. The Football Team has also allowed 560 receiving yards to players lined up in the slot in 2021, which ranks third-worst in the league. Add in the fact that the Chiefs will be without Clyde Edwards-Helaire, and they could come out with a more pass-heavy game plan than usual, especially against this defense.

Mark Andrews over 14.0 fantasy score - Andrews has been a machine in 2021 as he has seen 38 targets and hauled in 29 receptions for 400 yards and two touchdowns. He will be facing a Chargers' defense that has allowed tight ends to score an average of 21 points per game over the previous four weeks, which is ranked worst in the league. They have given up the seventh-most receptions (25) and the most yards (369) over that span. Andrews has the potential to be the number one tight end this week.

Jared Cook over 8.0 fantasy score - Jared Cook is the main tight end on the other side of the Chargers vs. Ravens game and he has a solid matchup as well. The Ravens have allowed an average of over 17 fantasy points per game to the tight end position over the previous four weeks, which is ranked eighth-worst in the league. Cook has seen 10 targets over the previous two weeks and could be in a spot to take advantage of this defense as they have also given up the sixth-most receptions to the position over the previous four weeks by allowing 25 of them.

Other Recommendations: James Robinson over 15.0 fantasy score, Ja'Marr Chase over 16.0 fantasy score, Jonathan Taylor over 16.0 fantasy score, Ricky Seals-Jones over 7.0 fantasy score, Hunter Henry over 9.0 fantasy score

Overall recommendation for this play: FLEX

 

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REAL-TIME FANTASY NEWS

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Questionable for Thursday
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Uncertain for Thursday
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Resting on Thursday Night
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Won't Play Wednesday Night
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Won't Play Against Denver
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Listed as Questionable for Thursday
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Iffy for Thursday
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Unavailable Thursday
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Remains Sidelined on Wednesday
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Remains Sidelined Wednesday
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Listed as Questionable for Thursday
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to Miss Thursday's Game
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Doubtful to Play Thursday Night
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Questionable to Play Thursday
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Downgraded to Doubtful Wednesday
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Ruled Out for Five Months
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Back From One-Game Absence Wednesday
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Available Against Kings
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Good to Go Wednesday
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Out Against Devils
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Misses First Game of the Season Wednesday
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Back in Action Wednesday
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Ruled Out for Sunday
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"Should be Good" to Face the Bears on Saturday
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has "a Good Chance" to Return in Week 16
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Back at Practice on Wednesday
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Will Start Again in Week 16
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Rehabbing ACL, LCL Tears
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Won't Practice Due to Concussion
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to Take Part in Wednesday's Walkthrough Practice
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Day-to-Day, Will Practice on Wednesday
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Jeremiyah Love Officially Heading to NFL Draft
Quinn Ewers

Making First Career Start in Week 16
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Being Benched by Dolphins
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Jake Merklinger Leaving Tennessee for Transfer Portal
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Jets, Jeremy Ruckert Agree to a Two-Year Extension
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Placed on Injured Reserve
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May Miss Another Game Wednesday
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Angels Open to Mike Trout Playing Center Field in 2026
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Misses Practice With Stinger
RJ Harvey

Dealing With Rib Injury
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Intends to Play Against Bears on Saturday
Zach Bogosian

Misses Tuesday's Game
Marcus Johansson

Unavailable Tuesday
Artyom Levshunov

Scratched for Tuesday
Mathew Barzal

a Game-Time Call Tuesday
Joseph Woll

Returns to Action Tuesday
Mike Matheson

Won't Play on Tuesday
Bam Knight

Cardinals Place Bam Knight on Injured Reserve
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Kansas State's Jayce Brown Intends to Transfer
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Nation's Leading Passer Drew Mestemaker to Enter Transfer Portal
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Michigan QB Jadyn Davis Set to Enter Transfer Portal
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Morgan Charriere Suffers First-Round Knockout Loss
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Gets First-Round Knockout Win
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And Marcus Buchecha Fight To Draw
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Lance Gibson Jr. Drops Decision In His UFC Debut
King Green

Gets Back In The Win Column
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Freddie Kitchens Fired from North Carolina Coaching Staff

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