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San Francisco 49ers D/ST Hard To Trust Despite Matchup

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Dec 20, 2025, 10:48 AM ET

The San Francisco 49ers D/ST allowed 24 points to the Titans in Week 15 and failed to record a turnover or a sack, even though Cam Ward is tied with two others as the most-sacked quarterback in the league. The 49ers have now recorded an interception in only three games, have 16 sacks on the season, and own the league's second-lowest pressure rate. In Week 16, San Francisco will take on the Colts, led by 44-year-old Philip Rivers. The rust was evident in Rivers' first game in five years when he faced the Seahawks last week, but Indy's strong offensive line should have no problem protecting him from the 49ers' impotent pass rush. Despite an inviting matchup due to the Colts' quarterback situation, the 49ers' track record in 2025 makes them hard to trust in the semi-final round of the fantasy football playoffs.--Dan Stephens
Source: NFL.com
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