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Thunder Dan's NFL Betting Picks for Week Two: Spreads, Totals, Parlays, and Teasers

Rashaad Penny - Fantasy Football Rankings, NFL Injury News, DFS Lineup Picks

Dan Palyo's top NFL betting picks and best bets for Week 2 of the 2022 season. His favorite NFL betting picks for player spreads, money lines, parlays, teasers, and game totals.

Football season is back! Whether you like to bet game totals, sides, or player props, I have something in here for you, and try to cover a little bit of everything!

This year, I started my own free sports betting newsletter, and the good people here at RotoBaller are allowing me to share my picks and data with you here in this space! You can access the free substack here and sign up for daily emails in addition to viewing the picks daily here on the RotoBaller website.

In this article, I'll be providing my favorite NFL betting picks for week two of the 2022 NFL season. The odds on these bets vary from book to book and are constantly changing. I primarily use FanDuel and DraftKings sportsbooks, but I would strongly encourage you to shop for the best odds at whatever books you use daily. I would also advise checking back later in the week as I may add bets depending on odds changing or specific props becoming available after I first post.

Be sure to check all of our fantasy football rankings for 2025:

 

Thunder Dan's Best Bets: 2022 NFL Season

  • Against the Spread: 2-2
  • O/U: 1-2
  • Overall: 3-4

 

NFL Betting Picks: Spreads

MIA (+3.5) vs. BAL (-110 DK)

The Dolphins looked good in week one and I think there’s a chance they are a better team than Baltimore this year. The Ravens won pretty handily in the second half but didn’t do much offensively other than one big passing play to Batemen. I think this Baltimore offense could struggle to score this year, and their defense will be tested here as Miami has some really nice weapons in the passing game. I’ll take the points on the road, but I think a small bet on the money line here is also warranted.

IND (-3.5) vs. JAX (-110 DK)

This line moved towards the Jags a half point, and I’m wondering why. Jacksonville was at least competitive in their opener but still lost to a Washington team that no one expects to be very good. The Colts scuffled to a tie against Houston in a game they were favored to win by a touchdown, but I doubt we see that happen again and it’s quite possible that Houston ends up being significantly better overall than Jacksonville. The Colts bounce back in a big way this week and cover this one easily.

SEA (+8.5) @ SF (-110 DK)

Seattle is the first of my three big road underdogs. Seattle probably shouldn’t have won last week, but they did. And their offense looked decent in the process. The Niners lost on the road in a bad weather game, and plenty of people are using that and the injury to Eli Mitchell to defend them. But I have had my doubts about Trey Lance going into this season, and I still have plenty of skepticism after week 1. I’m not Seattle can eke out a win here, but I think they keep it within a TD, this is simply too much cushion.

HOU (+10) @ DEN (-110 DK)

Another massive spread! When I see a double-digit spread, I think this has to be a major mismatch or I’m leaning towards the underdog. The talent gap in the NFL is much thinner than people realize, and we see upsets happen every week for a reason. Houston hung with Indy and forced a tie, while Denver blew it against Seattle last week. Of course, the Broncos are the better team, but they clearly still need time to gel on offense with Russ and his weapons and their defense allowed Seattle to move the ball for most of the game. Give me the Texans and the points!

CHI (+10) @ GB (-110 DK)

HOW ARE THE PACKERS FAVORED BY THIS MUCH? Again, a team that lost ugly last week is installed as big favorites. I watched the entire game with Minnesota and Green Bay looked BAD. They’re going to turn it around this quickly and suddenly dominate a division rival who should be pumped up after winning in Week one? Nah, the Bears will hang here and if the Packers do win, I don’t see them covering such a big spread. Once again, let’s take the dogs and gimme all those points!

 

NFL Betting Picks: Totals

KC-LAC over 54

Tonight’s game shoots out, I really believe that. These teams have a history of high-scoring affairs and averaged 58 combined points in two meetings last season. These offenses are pretty much intact from last year, other than Tyreek Hill missing from KC (who scored 44 without him last week), and the Chargers are without Keenan Allen due to injury.

This total jumped a few points right away and then settled in at 54. I was surprised it didn’t keep moving, so I imagine a decent chunk of money came in on the under. But I’m trusting my model (projects for 59 points) and my gut on this one.

 

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NFL Betting Picks: Teasers and Parlays

So let’s establish something here. I am going to post some money line parlays each week and at least one teaser. These bets carry more risk than straight bets, even if they seem like slam dunks! I try not to get too carried away and limit them to 3-4 games at the most. Play along if you like, or build your own. Most of these bets are half-units if you are wondering how to scale them to your other bets.

ML PARLAY: CIN/LAR/CLE/IND = (+230 DK)

The Browns should win at home against the Jets and both the Rams and Bengals are heavy faves in their game. Adding Indy’s ML to this one jumps the odds from +116 to +230, but I think it’s worth the risk.

6.5-point TEASER: MIA/SEA/HOU/CIN/CHI/CLE = (+500 DK)

We have our three big underdogs with even BIGGER cushions here, plus Miami boosed to +10. Then by going to 6.5 points we get CLE and CIN as basically money line bets. This is a big one, but it feels like a good one!

I hope you find my data and picks helpful and profitable! Thanks for checking out my picks and content here at RotoBaller!



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REAL-TIME FANTASY NEWS

Texas Rangers

Rangers, Bruce Bochy Mutually Agree to Part Ways
Darren Waller

Catches Two Touchdowns in First Game Back
Minnesota Twins

Rocco Baldelli Fired as Twins Manager
San Francisco Giants

Giants Fire Manager Bob Melvin
Francisco Alvarez

to Have Thumb Surgery in the Coming Days
Bo Bichette

Blue Jays Optimistic Bo Bichette Can Return for Division Series
Tyreek Hill

Believed to Have Suffered Dislocated Knee
Tyreek Hill

Carted Off in Week 4 With Knee Injury, Headed to Local Hospital
Lucas Giolito

Won't be on Wild-Card Roster With Elbow Issue
Alex Bregman

Should be Good for Game 1 of Wild-Card Series
Malik Nabers

Giants Officially Place Malik Nabers on Injured Reserve
Coby White

Limited to Start Training Camp
Lukas Dostal

Day-to-Day With Lower-Body Injury
Mattias Samuelsson

Out Week-to-Week
De'Aaron Fox

Likely Out For Season Opener
Bowen Byram

Considered Day-to-Day
Dylan Samberg

Ruled Out for 6-8 Weeks
J.T. Miller

Suffers Apparent Lower-Body Injury at Practice
Anthony Davis

Available For Training Camp
Tyson Foerster

Makes Preseason Debut Monday
Jalen Williams

Not Ready to Return
Alex Ovechkin

Logs Full Practice Monday
Ayo Dosunmu

Good to Go For Training Camp
Amen Thompson

Set to Lead Rockets' Offense With VanVleet Out
Nikola Jokić

Nuggets Eye Twin Towers With Nikola Jokic at the Helm
Bucky Irving

Comes Out of Week 4 With Injury
Bub Carrington

Reshapes Body, Ready for 2025-26 Season
Jauan Jennings

' Week 5 Status Up in the Air
Calvin Ridley

Dealing With Undisclosed Injury
Kenrich Williams

to Miss Time Following Knee Surgery
Cedric Tillman

to Miss Multiple Weeks
Brock Purdy

Toe Still Causing him Pain After Week 4 Loss
Chase Elliott

Steals the Win at Kansas and Locks Into the Round of 8
Chase Briscoe

Earns Another Top-Five Finish at Kansas
Christopher Bell

Finishes Third at Kansas Speedway on Sunday
Kyle Larson

Strong Kansas Performance Positions Him to Advance in the 2025 Playoffs
Joey Logano

Kansas Struggles End In Disappointment
Joe Mixon

Not Ready to Return
Kyrie Irving

Recovering "Quite Well," But Not Ahead of Schedule
Moritz Wagner

Without a Firm Timetable for Return
Jalen Suggs

Magic Targeting Opening Night for Jalen Suggs Return
Brandon Miller

is Healthy, Ready for Training Camp
Tyler Herro

Out for 8-12 Weeks
Malik Nabers

to Miss Remainder of 2025 With Torn ACL
Dominick Reyes

Suffers First-Round Knockout Loss
Carlos Ulberg

Gets First-Round Knockout
Romeo Doubs

has a Career Night, Scores Three Touchdowns
Ivan Erslan

Loses Third Fight in a Row
Ramon Taveras

Drops Decision At UFC Perth
Jack Jenkins

Gets Back In The Win Column
Jake Matthews

Suffers Third-Round Submission Loss
Neil Magny

Pulls Off Comeback Win
Noel Acciari

to Remain Out Monday
Vasily Podkolzin

Returning to Edmonton Tuesday
Mats Zuccarello

Without Timeline for Return
Charlie Campbell

Suffers First-Round Submission Loss
Tom Nolan

Gets First-Round Submission Win
Jonas Brodin

Returns to Full Practice
Alex Vlasic

Hurt on Sunday
Macklin Celebrini

Expects to Be Ready for Season Opener
Denny Hamlin

Despite Power-Steering Failure, Denny Hamlin Dominates and Finishes Second at Kansas
NASCAR

Bubba Wallace's Playoff Bid Likely Ends After Scrape With Boss at Kansas
William Byron

Runs Poorly, Still Finishes in the Top 10
Tyler Reddick

Finishes Seventh at Kansas Despite Distractions
Shane Van Gisbergen

Earns First Cup Series Top-10 Finish on an Oval
Puka Nacua

Injures Thumb Sunday, X-Rays Come Back Clean
George Pickens

Explodes as Top Receiver With Teammate Sidelined
Dak Prescott

Totals Four Touchdowns as Shootout Ends in Tie
Josh Jacobs

at the Center of Packers' Offense Again in High-Scoring Tie
Dallas Goedert

Leads Team in Receiving, Visits End Zone Twice
Gary Payton II

Staying with the Warriors
De'Anthony Melton

Returning to Golden State
Emeka Egbuka

Records Fourth Touchdown of 2025 in Week 4
James Cook

Tops 100 Rushing Yards for Third Straight Week
Pete Alonso

to Opt Out of Contract and Enter Free Agency
Travis Etienne Jr.

Dominates in Week 4 Win
Clayton Kershaw

Not Available for Wild-Card Series
Lamar Jackson

Suffers Hamstring Strain in Week 4, Set for Further Evaluation on Monday
Max Muncy

Expected to be Ready for Game 1 of Wild-Card Series
Bo Bichette

Without a Timeline, Unlikely to Return in Postseason?
Jared McCann

on Track to Be Available for Opening Night
Brandon Montour

Expected to be Available for Season Opener
Mason Marchment

Returns to Practice
Evan Rodrigues

Exits Practice Early Sunday
Anthony Stolarz

Signs Four-Year Extension With Maple Leafs
Cam Fowler

Blues Extend Cam Fowler for Three Years
Al Horford

Agrees to Join the Warriors
Noah Gragson

May Be A Sneaky DFS Option For Kansas Lineups
Todd Gilliland

Is A Quality Value Option for Kansas Lineups
Kyle Larson

the Favorite to Win at Kansas
Ryan Blaney

the Chalk DFS Play at Kansas
Denny Hamlin

Has Struggled at 1.5-Mile Tracks This Season
William Byron

a Solid DFS Pivot at Kansas
Alex Bowman

Will Alex Bowman's Top-10 Streak at Kansas Continue?
Ryan Preece

Should Have Speed at Kansas
Christopher Bell

Has Been Consistent at Kansas Despite Rarely Contending to Win
Joey Logano

Miserable Qualifying Result Makes Joey Logano a Top DFS Contender
Chase Elliott

Likely to Make Round of 8, but Has Hardly Been Inspiring
Ranger Suárez

Ranger Suarez Exits Early With Thigh Contusion in Loss
Trea Turner

to Return on Sunday
Ramón Laureano

Ramon Laureano Lands on 10-Day Injured List
Georges Niang

Set to Miss at Least Two Weeks
Jared McCain

to Miss 4-6 Weeks
Gradey Dick

Cleared for Training Camp
Brandon Ingram

Good to Go for Training Camp
JJ Peterka

Nursing Undisclosed Injury
Kirill Kaprizov

Dealing With Eye Infection
Brett Baty

Lands on 10-Day Injured List With Oblique Strain
Cade Horton

Goes on 15-Day Injured List With Fractured Rib
Jazz Chisholm Jr.

Exits After Hit by Pitch, X-Rays Negative
Josh Naylor

Suffering from "Minor Groin Tightness"
Pete Crow-Armstrong

Locks Up 30-30 Season
Giancarlo Stanton

Crushes Two Homers in Five-RBI Night
Josh Naylor

Exits With Apparent Injury on Friday
CFB

Caden Durham Doubtful for Saturday at Mississippi
Dominick Reyes

Looks For His Fourth Consecutive Win
Carlos Ulberg

Set For UFC Perth Main Event
Ivan Erslan

Looks For His First UFC Win
Jimmy Crute

A Favorite At UFC Perth
Jack Jenkins

Aims To Get Back In The Win Column
Ramon Taveras

An Underdog At UFC Perth
Neil Magny

Looks To Win Back-To-Back Fights
Jake Matthews

Looks To Extend His Win Streak
Louie Sutherland

Set For His UFC Debut
Justin Tafa

Looks To Get Back In The Win Column
Charlie Campbell

Looks To Remain Undefeated In The UFC
Tom Nolan

Set To Open Up UFC Perth Main Card
Viktor Hovland

Representing Team Europe at the Ryder Cup
Tommy Fleetwood

Representing Team Europe at the Ryder Cup
Scottie Scheffler

Representing Team USA at the Ryder Cup
CFB

Horatio Fields to Undergo Surgery on Broken Foot
CFB

Ole Miss To Start Trinidad Chambliss Against LSU
Sam Burns

Representing Team USA at the Ryder Cup
Matt Fitzpatrick

Representing Team Europe at the Ryder Cup
Bryson DeChambeau

Representing Team USA at the Ryder Cup
Shane Lowry

Representing Team Europe at Ryder Cup
Russell Henley

Representing Team USA at Ryder Cup
Robert MacIntyre

Robert Macintyre Representing Team Europe at the Ryder Cup
Patrick Cantlay

Representing Team USA at the Ryder Cup
Justin Rose

Representing Team Europe at the Ryder Cup
Harris English

Representing Team USA at the Ryder Cup

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