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Dylan Sampson Ruled Out Against Ravens
Cleveland Browns running back Dylan Sampson (knee) has been ruled out for Sunday's Week 6 matchup against the Baltimore Ravens, according to Daniel Oyefusi. Sampson injured his knee in the season opener against Jacksonville and will miss his fifth consecutive game. Cleveland opened his 21-day practice window Wednesday, but he didn't participate until Thursday, when he was limited. Sampson remains on injured reserve despite taking that step toward a return. His absence leaves the Browns with additional concerns in their backfield, as Quinshon Judkins (ankle) is questionable after returning to practice Friday. Raheim Sanders (hip) is also on injured reserve, leaving Jaleel McLaughlin and newly signed Audric Estime as potential options for increased work if Judkins cannot play. Sampson could return as early as Week 7 against Tennessee, although his availability has yet to be determined.
Source: Daniel Oyefusi
Source: Daniel Oyefusi
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Bucky Irving Has RB1 Upside for Week 6
Tampa Bay Buccaneers running back Bucky Irving is coming off his best performance of the season. Irving rushed for a season-high 165 yards on 21 attempts with a touchdown during last week's win over the Dallas Cowboys. He also hauled in two of his three targets for 10 yards and another score. The Bucs have been leaning on Irving lately with quarterback Jalon Daniels under center during the last two games. The expectation is that Irving will continue seeing a heavy workload during the upcoming Week 6 matchup against the Pittsburgh Steelers. A defensive unit that has allowed the 13th-fewest rushing yards in the league. Irving should be considered a borderline RB1 for this upcoming home matchup against the Steelers.
Source: Pro Football Reference
Source: Pro Football Reference
Caleb Williams Questionable Despite Full Practice Friday
Chicago Bears quarterback Caleb Williams (hamstring) practiced in full Friday but is listed as questionable for Sunday's Week 6 matchup against the Atlanta Falcons, according to Brad Biggs. Williams has missed three consecutive games since suffering a right hamstring injury against Minnesota in Week 2. He was also listed as a full participant Wednesday and Thursday, although Wednesday's session was a walkthrough. Williams revealed Thursday that he suffered a hamstring tear and still needed to complete additional medical testing before receiving clearance to play. Through his first two games, he threw for 407 yards and two touchdowns while rushing for 107 yards and two more scores. His rushing ability has been an important part of his fantasy production, making his recovery particularly relevant for managers considering starting him. The full practices are encouraging, but his availability remains uncertain until the Bears make a final decision.
Source: Brad Biggs
Source: Brad Biggs
Jalon Daniels Offers Low-End QB2 Value for Week 6
Tampa Bay Buccaneers quarterback Jalon Daniels will remain the starter for at least one more week. The Bucs were hopeful that Baker Mayfield (thumb) would be ready, but he'll miss at least one more game because of his dislocated thumb. Daniels was surprisingly efficient during last Thursday's win over the Dallas Cowboys. He completed 19-of-25 passing attempts for 189 yards with one touchdown and zero interceptions. He also rushed the ball seven times for an additional 23 yards on the ground. The Bucs will likely continue to use a run-first offense, which will limit Daniels' overall upside. Fantasy managers should consider Daniels a low-end QB2 in superflex formats for the Week 6 matchup against the Pittsburgh Steelers.
Source: Pro Football Reference
Source: Pro Football Reference
KC Concepcion Jr. Cleared for Week 6
Cleveland Browns rookie first-round wide receiver KC Concepcion Jr. (concussion) has been cleared from the league's concussion protocol and does not have an injury designation for Week 6 on Sunday against the division-rival Baltimore Ravens, according to ESPN's Daniel Oyefusi. Concepcion suffered a scary concussion on a head-to-head hit early in the Week 5 loss to the New York Jets, so it is a bit of a surprise that he will be available this weekend. The 22-year-old 24th overall pick back in April from Texas A&M has been a nice one-two punch with fellow rookie Denzel Boston in the Browns' offense, with both rookie receivers pushing veteran Jerry Jeudy down the depth chart. Concepcion has 18 receptions for 149 yards and is still searching for the first touchdown of his NFL career through his first five contests. Now that we know Concepcion will play against the Ravens, he will be in play as a WR4/flex option for fantasy managers in the divisional tilt.
Source: ESPN.com - Daniel Oyefusi
Source: ESPN.com - Daniel Oyefusi
TreVeyon Henderson Questionable for Sunday Against Jets
New England Patriots head coach Mike Vrabel said that running back TreVeyon Henderson (ankle) is questionable for Sunday's divisional clash against the New York Jets in Week 6, according to Mark Daniels of MassLive.com. This should be considered a best-case scenario for Henderson's fantasy managers after he was expected to miss multiple weeks following his ankle injury in the Week 5 win over the Las Vegas Raiders on Sunday. The 23-year-old was able to practice all week in a limited fashion, but instead of being out multiple weeks, he will have a chance to suit up on Sunday against the division-rival New York Jets. On the flip side, it will be hard to trust Henderson as a fantasy starter, even if he makes a remarkable turnaround to play this weekend. Henderson missed the season opener due to injury and has been the RB2 behind Rhamondre Stevenson, carrying the ball 42 times for 163 yards (3.9 yards per carry) and one touchdown while catching only two passes for 22 yards. Stevenson will have RB1 upside against Gang Green if Henderson is ruled out.
Source: MassLive.com - Mark Daniels
Source: MassLive.com - Mark Daniels
Chris Olave Questionable for Week 6 With Illness
New Orleans Saints wide receiver Chris Olave (illness) will be listed as questionable with an illness for Week 6 on Sunday on the road against the New York Giants, according to Saints reporter Jeff Nowak. Olave has been under the weather this week and did not practice with the team on Wednesday or Thursday. The 26-year-old high-end pass-catcher returned to the practice field on Friday, though, which is a good sign that he will be available for Sunday's road tilt against the New York Giants in Week 6. We should have a better idea by Sunday morning whether Olave is seriously in danger of missing this weekend's game, but for now, fantasy managers should plan on having him available as the Saints look to break their losing streak. Olave, a former first-rounder from Ohio State, is a must-start receiver in fantasy when he is active. Going into Week 6, he ranks as the WR6 in half-PPR scoring, catching 39 of 54 targets for 537 yards and one touchdown. His 54 targets rank third among all wideouts, behind only Jaxon Smith-Njigba (one more game) and Amon-Ra St. Brown.
Source: Jeff Nowak
Source: Jeff Nowak
A.J. Brown Officially Questionable for Week 6
New England Patriots head coach Mike Vrabel said that wide receiver A.J. Brown (ankle) is questionable to play in Week 6 on Sunday at home against the division-rival New York Jets, according to Mark Daniels of MassLive.com. The Patriots want to see how Brown responds after Friday's practice. The 29-year-old is on the verge of returning from Injured Reserve after he suffered a high-ankle sprain in the Week 1 loss to the Seattle Seahawks. He was limited in practice on Wednesday and Thursday. The former second-rounder from Mississippi is a question mark for Week 6, but fantasy managers will know one way or another if he will be active against the Jets if the Patriots officially activate him from IR by Saturday afternoon's deadline. If given the green light to return this weekend, Brown will be a volatile fantasy football option after a long layoff with the potential to see a reduced workload. Eventually, though, Brown will reprise his role as the No. 1 receiver for quarterback Drake Maye.
Source: MassLive.com - Mark Daniels
Source: MassLive.com - Mark Daniels
Rashee Rice Out for Sunday Against Chargers
Kansas City Chiefs head coach Andy Reid said that wide receiver Rashee Rice (hamstring) is out for Sunday's Week 6 game against the division-rival Los Angeles Chargers, according to Nate Taylor of ESPN. Rice suffered a hamstring injury in the Week 4 win over the division-rival Las Vegas Raiders, but despite having a bye last week to recover, the Chiefs do not want to put him out there this weekend. The 26-year-old's absence will open up more targets for receiver Xavier Worthy and veteran tight end Travis Kelce against the winless Chargers. Rice's absence is very disappointing for fantasy managers, but hopefully he can return to practice next week and be back for a Week 7 showdown against the Seattle Seahawks. He has been relatively quiet despite the team's 5-0 start in 2026, catching 13 of his 17 targets for 190 yards and just one touchdown in four games played. In deeper fantasy leagues this weekend, rookie Cyrus Allen, who generated a lot of fantasy buzz during the preseason, could be in consideration as a flex play against the Bolts with Rice out.
Source: ESPN.com - Nate Taylor
Source: ESPN.com - Nate Taylor
Quinshon Judkins Deemed Questionable for Week 6
Cleveland Browns running back Quinshon Judkins (foot) is listed as questionable on the team's final injury report for Week 6 against the division-rival Baltimore Ravens, according to Daniel Oyefusi of ESPN. Judkins made an early exit from Sunday's Week 5 loss to the New York Jets with a foot injury and then missed practice on Wednesday and Thursday. The 22-year-old second-year back from Ohio State managed to return to practice on Friday, but it does not necessarily mean he will be active come Sunday against Baltimore. Fantasy managers will need to keep a close eye out for updates on his status leading up to Sunday morning. Backfield mate Raheim Sanders (hip) was placed on Injured Reserve this week, and it remains unclear if Dylan Sampson (knee) will come off IR to play this weekend. If neither Judkins nor Sampson can play against Baltimore, Jaleel McLaughlin and Audric Estime would be sharing snaps in Cleveland's backfield. Judkins is trending as a risky low-end RB2 in fantasy this week due to his injury.
Source: ESPN.com - Daniel Oyefusi
Source: ESPN.com - Daniel Oyefusi
Jeremiyah Love Will Not Play in Week 6
Arizona Cardinals running back Jeremiyah Love (ankle) has been ruled out of Sunday's Week 6 divisional matchup with the Rams, according to team reporter Darren Urban. After missing practice on both Wednesday and Thursday, head coach Mike LaFleur told reporters that the rookie's injured ankle requires further rest. The third overall pick in the 2026 NFL Draft, Love has disappointed fantasy managers early in his career, averaging 3.7 yards per carry, adding only 11 receptions, and being kept out of the end zone in three of five games, with much of his inefficiency likely tied to the ailing ankle dating back to his preseason injury. With Love inactive, veteran Tyler Allgeier could be in line for a bell cow workload and becomes a must-start against a Rams defense that has been middle-of-the-pack against fantasy running backs.
Source: Darren Urban
Source: Darren Urban
Lamar Jackson Ruled Out for Sunday
Baltimore Ravens quarterback Lamar Jackson (ankle) will miss his second straight game after head coach Jesse Minter announced on Friday that he has been ruled out for Sunday's divisional matchup with the Browns. Veteran Tyler Huntley will start again after leading the team to an overtime victory over the Falcons in Week 5 and keeping the offense largely on track, as he's been known to do in his time as Jackson's backup. While the fantasy ceilings of running back Derrick Henry and Zay Flowers are ultimately lowered without Jackson under center, Baltimore's Plan B is better than most, and both can still be started with only slightly tempered expectations.
Source: Jamison Hensley
Source: Jamison Hensley
Michael Penix Jr. Cleared to Start Sunday
Atlanta Falcons quarterback Michael Penix Jr. (ribs) is off the injury report and set to start the team's Week 6 matchup with the Bears, according to NFL Insider Ian Rapoport. After being knocked out of the Falcons' Week 5 overtime loss to the Ravens with a rib injury, Penix has logged a full week of practice participation and carries no injury designation into Sunday. Since returning in Week 3 from the knee injury that ended his 2025 season, Penix has been the fantasy QB20 while notably elevating the ceilings of Bijan Robinson, Drake London, and tight end Kyle Pitts Sr. In a Bears matchup with one of the week's highest over/unders, all of Atlanta's usual playmakers can be started with confidence, though Penix himself is RotoBaller's QB25.
Source: Ian Rapoport
Source: Ian Rapoport
Jalen Coker Healthy and Set to Play Sunday
After a quadriceps injury knocked him out of the team's Week 3 loss to the Browns and kept him sidelined for one more game before the bye week, Carolina Panthers wide receiver Jalen Coker (quadriceps) logged three straight full practice participations this week and carries no injury designation into Sunday's matchup with the Eagles. Coker was the Panthers' leading receiver through the first three weeks of the season before his absence allowed 2025 Offensive Rookie of the Year Tetairoa McMillan to post career highs of 14 receptions and 192 yards in the team's Week 4 win over the Lions. With the Panthers' passing attack back to full health, fantasy managers should find value in an above-average matchup with the Eagles, though Coker could struggle to match some of his early-season highs, and he is RotoBaller's WR20.
Source: Mike Kaye
Source: Mike Kaye
TreVeyon Henderson Practicing Again on Friday
New England Patriots running back TreVeyon Henderson (ankle) was present again for the start of Friday's practice, according to team reporter Mark Daniels, capping off three straight days of practice after sustaining an ankle injury in the team's Week 5 win over the Raiders. Henderson was initially feared to be facing a multi-week absence, but after surprising with limited participation on Wednesday and Thursday, and showing up again on Friday, he has a chance to suit up for the team's divisional clash with the New York Jets on Sunday. Outside of one long run in a Week 2 win over the Steelers, Henderson has been inefficient in his second season, averaging 3.9 yards per carry and finding the end zone only once after scoring 10 times as a rookie. As such, even if active, he should be viewed as little more than a flex play despite a favorable matchup against the Jets.
Source: Mark Daniels
Source: Mark Daniels
A.J. Brown Loosening Up for Friday's Practice
New England Patriots star wide receiver A.J. Brown (ankle) was seen loosening up along the sidelines as the team's practice got underway on Friday, according to Mike Reiss of ESPN. Brown has practiced all week, albeit limited, as he potentially looks to come off Injured Reserve to play this weekend against the division-rival New York Jets. We will know whether Brown is going to play in Week 6 by Saturday, when the Patriots would have to officially activate him from IR if they plan on using him on Sunday. The 29-year-old big offseason acquisition suffered a high-ankle sprain in the Week 1 loss to the Seattle Seahawks and has been out since then. If Brown is activated and plays on Sunday, he will be volatile in starting fantasy lineups while potentially being at risk of having his snaps limited. The three-time Pro Bowler caught three passes for 26 yards in the season opener before his ankle injury. He will look to immediately re-establish a connection with quarterback Drake Maye as the team's No. 1 wideout when he returns.
Source: ESPN.com - Mike Reiss
Source: ESPN.com - Mike Reiss
Saquon Barkley has Missed Practice All Week
Philadelphia Eagles running back Saquon Barkley (hamstring) is not at practice on Friday and has missed practice all week, according to Dave Zangaro of NBC Sports. Injuries have hit the Eagles' offense hard of late, with Barkley tweaking his hamstring in the Week 4 loss to the Los Angeles Rams and not playing in the Week 5 loss to the Jacksonville Jaguars on Sunday. Barring something unforeseen, he is trending towards missing a second straight game this Sunday against the visiting Carolina Panthers. After Will Shipley's foot injury in London last weekend, the Eagles are down to Dameon Pierce and Carson Steele in the backfield, with Tank Bigsby (abdomen) still on Injured Reserve. And if that was not enough, star quarterback Jalen Hurts (calf) is now out indefinitely with a superficial blood clot. Fantasy managers should be planning to be without Barkley for a second straight game, and when he does return, his fantasy ceiling will be lowered if Hurts remains sidelined. The next chance for Barkley to return will be in a Week 6 Monday night showdown against the division-rival Dallas Cowboys.
Source: NBC Sports - Dave Zangaro
Source: NBC Sports - Dave Zangaro
Stefon Diggs at Practice on Friday
Washington Commanders wide receiver Stefon Diggs (hamstring) is at practice on Friday working with the rest of the receivers in individual drills, according to Zach Selby of the team's official website. Diggs injured his hamstring in the Week 4 loss to the Indianapolis Colts in London and did not play in last week's tie to the division-rival New York Giants. The 32-year-old veteran missed the first practice of the week on Thursday, but his return on Friday means that he is trending in the right direction to play on Monday night in Week 6 versus the 5-0 San Francisco 49ers. It is good news for Washington's offense, but Diggs is going to be a tough sell for starting fantasy lineups this week if he receives a questionable tag and is a game-time decision for Monday night. He has 18 catches for 170 yards and three touchdowns in his first four games for the Commanders this year. If Diggs misses a second straight game, rookie Antonio Williams would serve in the WR2 role again behind Terry McLaurin.
Source: Commanders.com - Zach Selby
Source: Commanders.com - Zach Selby
Jacory Croskey-Merritt Not Seen at Friday's Practice
Washington Commanders running back Jacory Croskey-Merritt (groin) was not seen at Friday's practice, which would be the second straight practice that he has missed with a groin injury, according to Tashan Reed of The Washington Post. The 25-year-old was limited in two practices last week due to a groin injury, but he was active in the Week 5 tie to the division-rival New York Giants and handled 11 carries for 82 yards and a touchdown on the ground while not being targeted in the passing game. It is unclear if the second-year back has suffered a setback with his groin injury or if the Commanders are simply resting their RB1 going into a Week 6 tilt on Monday night against the San Francisco 49ers. The good news is that JCM has one more day to potentially return to practice on Saturday, but as of now, he is looking questionable to play in Week 6. If Croskey-Merritt cannot go on Monday night, Rachaad White would jump into the featured-back role for the Commanders, albeit in a tough matchup on the road against the 5-0 Niners.
Source: The Washington Post - Tashan Reed
Source: The Washington Post - Tashan Reed
Lamar Jackson Missing Another Practice on Friday
Baltimore Ravens quarterback Lamar Jackson (ankle) is not present during the media-viewing portion of Friday's practice, which indicates that backup Tyler Huntley will likely start for the second straight week this Sunday against the division-rival Cleveland Browns, according to Jamison Hensley of ESPN. Jackson missed every practice this week and has not suited up since spraining his left ankle in the Week 4 win over the Tennessee Titans. Huntley has won his last three starts as a fill-in starter for Jackson, so they definitely are not going to rush Jackson back if he is not quite ready. In the three victories with Huntley under center, the Ravens have averaged 33.7 points. Huntley has become one of the better backups in the league, and he will once again be on the QB2 streaming radar in superflex fantasy leagues if he makes his second straight start. Fantasy managers should be ready to be without Jackson for a second straight week. If he is ruled out on Friday, his next chance to play will be at home for another divisional contest on Sunday, Oct. 25, against the Cincinnati Bengals.
Source: ESPN.com - Jamison Hensley
Source: ESPN.com - Jamison Hensley
DeVonta Smith Practicing on Friday
Philadelphia Eagles wide receiver DeVonta Smith (hamstring) is practicing with the team on Friday, which is a good sign for his availability in Week 6 against the visiting Carolina Panthers, according to Zach Berman of The Athletic. Smith has missed the last two games after injuring his hamstring in the Week 3 loss to the Chicago Bears on Monday Night Football. The 27-year-old did not practice on Wednesday, but he returned to the field on Thursday and was listed as limited. Smith could very well take a questionable tag into the weekend, but with back-to-back days of practice, he is trending up to return to action against the Panthers. The bad news for Smith is that starting quarterback Jalen Hurts (calf) is out indefinitely with a superficial blood clot, so if he plays on Sunday, he will be working with backup Tanner McKee. Smith is an easy fade in DFS if he is active this weekend, with McKee running the show on offense for Philadelphia, and fantasy managers in single-year leagues may want to consider benching him as well if he is active.
Source: The Athletic - Zach Berman
Source: The Athletic - Zach Berman
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