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Yahoo! Daily Fantasy Football Lineup Picks (Week 6): NFL DFS Advice

Justin Klein's week six Yahoo lineup picks. Daily fantasy football sleepers, value picks and lineups advice for Yahoo DFS games and tournaments.

Welcome to RotoBaller's Yahoo! daily fantasy football lineup picks for Week 6 of the NFL season. In this article, I, Justin Klein, will be taking you, the reader, through the best Yahoo! DFS plays of the week for this upcoming Sunday.

These Yahoo! lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. Good luck with your Yahoo! DFS lineups!

Editor's Note: If you like Yahoo, be sure to also check out FantasyAces. New users that sign up on Fantasy Acesand make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

Be sure to check all of our fantasy football rankings for 2025:

 

Yahoo! Quarterback - Week 6 DFS Picks

Matt Stafford (vs LA, $32)

Stafford is fairly cheap this week and I love his matchup with the Rams at home. There are certainly better options, but Matt is the cheapest one that I like, so he gets the write up. Not only are the Rams coming into Detroit injured, as Robert Quinn and Trumaine Johnson are both questionable, but they're also allowing 242 passing yards per game. I believe that number goes up this week as Stafford nears 300 yards with multiple touchdown throws.

 

Yahoo! Running Backs - Week 6 DFS Picks

Christine Michael (vs ATL, $24)

Michael has a juicy matchup at home this week as the Falcons come into Seattle. Atlanta has allowed the fifth most points to opposing backfields this season and Seattle will no doubt look to control the clock and run the ball even more than usual to keep it away from the red hot Falcons offense. When you also factor in that Michael has been a top 12 scorer in every week thus far and that he's under $25, we have a bit of a no-brainer here folks.

Lamar Miller (vs IND, $28)

Lamar Miller has been steady and reliable this season despite the fact that he's yet to score a touchdown. I believe that will change this week and he finally gets into the end zone. Even if he doesn't he should be a solid play as he's received 47% of Houston's touches this season, the second highest share of team touches for any running back in the league. It also bodes well that the Colts have allowed 15 or more points to six different running backs on the season, the most in the league. On top of that 41.1 yards per drive, which is also the most in the league.

 

Yahoo! Wide Receivers - Week 6 DFS Picks

Tavon Austin (at DET, $17)

Austin has managed to accumulate a touch or a target on 22% of the Ram's offensive snaps, which is the highest total for any wide receiver. The fact that he's just $17 makes him a must start and a terrific value play. While LA will no doubt look to get Gurley going this week, Detroit happens to be the only team that is yet to allow a rushing TD. This bodes well for Austin as LA is more likely to be forced to score through the air.

Cameron Meredith (vs JAX, $14)

Meredith stepped in for Kevin White last week and made a huge impact as he totaled nine catches for 130 yards and a touchdown on 12 targets. He did that while playing 93% of the Bears snaps and receiving nearly 30% of their targets. This week he'll face a Jaguars defense that is 27th in efficiency to WR2's and is quite cheap at $14. For all those reasons he makes for a strong value option at WR.

 

Yahoo! Tight End - Week 6 DFS Picks

Travis Kelce (at OAK, $23)

Oakland has allowed a league high 331 passing yards per game this season as well as 10.1 yards per target to opposing tight ends, which is also the highest in the league. That alone is enough to make Kelce a magnificent play. When you add in that Travis has been a top 10 option in three of his four games it makes this matchup even better. I think Kelce will explode this week and is a great play in every format; so join me and get him in all of your lineups.

 

Yahoo! Defense - Week 6 DFS Picks

Buffalo Bills D/ST (vs SF, $16)

The Bills are nine point favorites at home against a San Francisco offense that has struggled mightily this season. They've been so bad that they're turning to their backup QB, Colin Kaepernick, this Sunday. While Blaine Gabbert might have provided even more points for the Bills defense Kaepernick will do just fine in his stead. The fact that the 49ers rank dead last in yards per game isn't going to change that much with a QB change. The Bills D/ST is averaging a healthy 13.8 fantasy points per game and I expect that number to rise this weekend. Buffalo has managed three or more sacks in four of their five games this season. The 49ers rank last in the league at pass attempts per game, so that number could come down, but Buffalo will no doubt stack the box and force Kaepernick and the 49ers into throwing mistakes as a result.




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REAL-TIME FANTASY NEWS

CBJ

Brendan Smith Joins Blue Jackets on Tryout Deal
STL

Milan Lucic Joins Blues for Tryout
DET

Red Wings Pick Up Travis Hamonic
Austin Riley

Doesn't Appear Ready to Return Any Time Soon
Aaron Judge

Unikely to Throw Normally Again This Year
Jalen McMillan

Could be Out Through Week 9 Bye
Indiana Pacers

Pacers Coach Rick Carlisle Agrees to a Multiyear Contract Extension on Tuesday
Washington Wizards

John Wall Retires After 11 NBA Seasons
Daniel Jones

Named as Colts Starting Quarterback
Jalen McMillan

Will Not Be Ready for Season Opener
Collin Sexton

Hornets Have High Hopes for Collin Sexton
Rui Hachimura

Likely to Start Season Without Contract Extension
Jaime Jaquez Jr.

Hopes to Bounce Back in 2025-26
Stephen Curry

Ready to Go for New Season
Orlando Magic

Lester Quinones Agrees to Deal With Magic
Luka Dončić

Luka Doncic Cleared to Play on Tuesday Night
Vladimir Guerrero Jr.

Pulled With Hamstring Tightness
MLB

Game 2 of Brewers-Cubs on Monday Postponed
Bryce Miller

to be Activated on Tuesday
Kyle Tucker

to Get Multiple Days Off
Shane Bieber

to Make Season Debut on Friday
Joe Mixon

Could Start Season on NFI List
Zack Wheeler

has Surgery to Remove Blood Clot
De'Von Achane

Unlikely to Practice This Week
Justin Jefferson

Returning to Practice
Chris Godwin

Bucs Chris Godwin Likely to Start Season on PUP List
Joe Flacco

Browns Name Joe Flacco as Their Week 1 Starter
Jalen McDaniels

Inks Deal With New Orleans
N'Faly Dante

Signs Deal With Hawks
Matthew Stafford

Practicing on Monday
Dru Smith

Agrees to Deal With Heat
Austin Dillon

Scores an Upset Victory at Richmond
William Byron

Clinches the Regular Season Championship Title at Richmond
Denny Hamlin

Pit-Road Struggles Impede Denny Hamlin's Chances of a Top Finish at Richmond
Joey Logano

Earns A Fourth-Place Finish at Richmond
Kyle Larson

Rallies to A Top-10 Finish at Richmond
Malik Nabers

Dealing With Back Injury
Khamzat Chimaev

Is The New UFC Middleweight Champion
Dricus Du Plessis

Gets Dominated At UFC 319
Aaron Pico

Suffers Knockout Loss In His UFC Debut
Lerone Murphy

Scores Stunning First-Round Knockout
Leodalis De Vries

Earns Promotion to Double-A
Nathaniel Lowe

Finalizing Deal with Boston
Geoff Neal

Suffers First-Round Knockout Loss
Ketel Marte

Arizona Could Trade Ketel Marte in the Offseason
Carlos Prates

Gets Back In The Win Column
Michael Page

Dominates At UFC 319
Jared Cannonier

Gets Outclassed
Tim Elliott

Gets Submission Win
Kai Asakura

Still Winless In The UFC
Austin Cindric

has Arguably his Best Run of the Season at Richmond
Ryan Blaney

Contends for First Richmond Win but Comes Up Short
Alex Bowman

Finishes Second but Loses Ground in Playoffs
NASCAR

Bubba Wallace Sets Personal Laps-Led Record at Richmond
Chris Buescher

Falls Out of Playoffs After Miserable Richmond Run
Coby White

Bulls Not Interested in Trading Coby White
Dereck Lively II

Expected to be Ready for Camp
Brian Robinson Jr.

Commanders "Shopping" Brian Robinson Jr.
John Metchie III

Texans Trade John Metchie III to Eagles
Victor Scott II

Placed on 10-Day Injured List
Trey Hendrickson

Bengals Listening to Trade Offers for Trey Hendrickson
Marcelo Mayer

to Have Season-Ending Wrist Surgery
Samuel Basallo

Called Up From Triple-A Norfolk
J.K. Dobbins

Expected to Win Starting RB Job?
Quentin Johnston

Suffers Concussion in Preseason Loss
Jaxson Dart

Plays Well on Saturday Night
Marcus Semien

Avoids Serious Injury
Kyle Stowers

Heads to Injured List With Left-Side Strain
Zack Wheeler

Placed on Injured List With Blood Clot in Shoulder
Terry McLaurin

Commanders Optimistic Terry McLaurin Deal Can Get Done Soon
De'Von Achane

De’Von Achane Dealing With Lower-Body Injury
Luka Dončić

Luka Doncic Likely Avoids Serious Injury
Josh Hader

Unlikely to Return During Regular Season
Denny Hamlin

the Heavy Favorite to Win at Richmond
Christopher Bell

Has Been Great at Richmond
Kyle Stowers

Out Saturday With Left-Side Tightness
Tyrese Haliburton

No Longer Using a Scooter, Crutches
Ryan Blaney

Can Ryan Blaney Finally Break Through at Richmond?
Joey Logano

Will Start Last at Richmond After Practice Trouble
Chase Elliott

Lack of Top-Line Speed Hurts his DFS Potential
Kyle Larson

Recent String of Crashes Make Him a Big Risk at Richmond
William Byron

Probably Slightly Too Inconsistent at Richmond to Start for DFS
Ryan Preece

on Pole at Richmond as Playoff Deadline Looms Closer
Brad Keselowski

Probably the Best RFK Racing DFS Option at Richmond
Chase Briscoe

Still Figuring Out Richmond
Chris Buescher

a Solid Choice for DFS Play, but Teammates Look Faster
Jhoan Duran

Feels "100%"
Marcus Semien

Out on Saturday, Going for X-Rays on his Wrist
Terry McLaurin

Commanders Activate Terry McLaurin From PUP List
Rashee Rice

NFL Could Reach Settlement Before Hearing
Joe Mixon

Not a Lock to be Ready For Week 1
Haywood Highsmith

Dealt to Brooklyn on Friday
Amir Coffey

Signs One-Year Deal With Bucks
Khamzat Chimaev

A Favorite At UFC 319
Dricus Du Plessis

Set For His Third Title Defense
Aaron Pico

Set For UFC Debut
Lerone Murphy

Looks To Remain Undefeated
Geoff Neal

Looks For His Second Win In A Row
Michael Page

Set For His Second Middleweight Bout
Jared Cannonier

Looks To Win Back-To-Back Fights
Kai Asakura

Looks For His First UFC Win
Tim Elliott

Set To Open Up UFC 309 Main Card
CBJ

Mikael Pyyhtia Re-Signs With Blue Jackets for One Year
UTA

Caleb Desnoyers Expected to Miss 12 Weeks After Wrist Procedure
Tyson Foerster

on Track to Be Healthy for Season Opener
NHL

Olivier Rodrigue Signs KHL Deal
NHL

Emil Bemstrom to Join Swiss Team
Payton Pritchard

Reportedly Moving Into Starting Lineup
Kevin Durant

Rockets Not Interested in Keeping Kevin Durant with Max Extension
NBA

Isaiah Mobley Joins Turkish Team
NBA

Cole Swider Links Up with EuroLeague Powerhouse

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