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QB vs Pass Rush Matchups To Watch - Week 16

Gage Bridgford (@GbridgfordNFL) identifies quarterbacks to watch in Week 16 based on the opposing pass rush defense. These QBs could be players to fade and avoid or to start and stream in fantasy football leagues.

Week 16 is here, and fantasy championships are on the line. Some teams head into the fantasy finals as big favorites but others are scrapping to pull off a big win as underdogs. Real teams start at quarterback, and the position is pretty important for fantasy as well.

Quarterbacks have changed the game for fantasy football this year with guys like Lamar Jackson and Josh Allen taking full advantage of their running ability to stress defenses. It gives you more viable options on a week-to-week basis.

Right now, these are the weeks that we've spent months preparing and competing for. There's no room for an error, and it's not time to get cute. We have to set our best lineups to win because we aren't coming back next week if we don't.

Be sure to check all of our fantasy football rankings for 2025:

 

Look Away Before It Gets Ugly

Jared Goff @ San Francisco 49ers

You're telling me that Los Angeles Rams quarterback Jared Goff has to go on the road in a do-or-die game against one of the best teams in the conference. I don't like his odds. His offensive line has struggled to generate time for their quarterback despite only giving up 21 sacks this season. In the previous matchup between these two teams, Goff was taken down four times. So, one-fifth of his sacks came in one game, and that was at home.

One issue for the San Francisco 49ers Defense is that they're dealing with several injuries to their pass rush. However, they're still trotting out one of the most fearsome fronts in football from Nick Bosa to Arik Armstead and everyone in between. They have 47 sacks on the year, and, with two games remaining, they would have finished as a top-10 team in sacks last season. This group gets after the quarterback, and, in their fight for playoff seeding, they'll be wanting to make a statement on Saturday night.

 

Sam Darnold vs Pittsburgh Steelers

This Pittsburgh Steelers team is not the best in football, but, with the collection of players that they've been trotting out, they're playing far better than anyone would have expected. It's been largely on the back of their defense. They've gotten an NFL best 49 sacks thus far, and they'll likely be adding to that total in Week 16. They control their playoff destiny if they're able to win in each of the final two weeks. Week 17 isn't guaranteed against a hot Baltimore Ravens team, but they can make life a lot easier with a win this week.

New York Jets quarterback Sam Darnold has been hit a lot this year, as the team has given up 48 sacks on the season. He's also been extremely inconsistent. After seeing ghosts against the New England Patriots, he had a hot few games, but they've also lost to two winless teams (at the time) in the Miami Dolphins and Cincinnati Bengals. They're eliminated from playoff contention, and they have nothing to play for other than draft positioning. Additionally, the dynamic between him and head coach Adam Gase will be interesting to watch after their sideline blowup last week.

 

Daniel Jones @ Washington Redskins

First things first, why are the New York Giants playing Daniel Jones (ankle) despite his high ankle sprain? You just spent a first-round pick on the guy, and you're bringing him back literally two weeks after an injury that typically takes multiple weeks to recover from. This offensive line has allowed 38 sacks this season, and his mobility will likely be limited by the injury. New York just lost tight end Evan Engram (foot) for the remainder of the season, and these final two weeks will not be an amazing swan song.

The Washington Redskins have shown life in recent weeks with quarterback Dwayne Haskins under center, and their defense has also shown some improvement. They're fifth in the NFL with 42 sacks, and they want to see what they have in this rookie with the year nearly over. This is an audition for their next head coach whether that is Urban Meyer or someone else. In a battle of two terrible teams in lost seasons, I think Washington gets after Jones early and often.

 

That's More Like It

Gardner Minshew @ Atlanta Falcons

I would like Jaguars quarterback Gardner Minshew a lot more if this were a home game, but, I still like him this week. No longer under the reign of the almighty Tom Coughlin, this Jaguars team is going to come out and make a statement, and a lot of that is going to be by running the ball and throwing against an overmatched Falcons Defense. The Jaguars are in the top half of the NFL in sacks allowed. Additionally, both of his starting wide receivers are expected to be healthy for this dome contest with D.J. Chark apparently over an ankle injury that cost him the previous game.

The Falcons are led by a defensive-minded head coach, but they've been a lot more bark than bite for a few years. This season, they have just 24 sacks through 14 games. The strength of their pass rush is on the inside with stud defensive tackle Grady Jarrett, but the strength of the Jaguars offensive line is on the interior. The matchups aren't in their favor, and, in a sneaky shootout, the odds favor the Jaguars in this one.

 

Kyler Murray @ Seattle Seahawks

Arizona Cardinals quarterback Kyler Murray has performed about as well as one could have hoped entering the year. He has used his running ability to keep his fantasy floor high, and, despite playing behind a struggling offensive line, he gets the ball out to his receivers. The team is averaging about 22 points per game, and they're going to be forced to score a lot against one of the NFL's top-10 offenses.

Thankfully for Murray and Arizona, the Seahawks don't have the fierce pass rush that they had earlier in the decade. They have just 24 sacks this season, and they're giving up over 24 points per game. This defense allows points, and the offense is often tasked with bailing them out. Murray will find his opportunities to score despite his offensive line's struggles.

 

Drew Lock vs Detroit Lions

Fading the Detroit Lions Defense has been a good strategy for most of the year. They don't have any form of a pass rush, and their secondary, outside of veteran cornerback Darius Slay, can't cover anyone. Drew Lock came back to earth last week against a sneaky good Kansas City Chiefs Defense, but he has the matchup to rebound this week. His offensive line has only allowed three sacks in the three games he has played, and the Lions aren't the type of group that could drastically increase that total.

The Lions have 27 sacks this season with 14.0 of those sacks coming from two players in the forms of Trey Flowers and Devon Kennard. Outside of those two, the next-highest player on the team has just two. If Denver can slow down those two, it's going to be next to impossible for Detroit to generate any pressure. Lock isn't an ideal play, but he's far from the worst on this week's slate.

More Weekly Lineup Prep




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REAL-TIME FANTASY NEWS

Justin Herbert

Expected to Practice Either Thursday or Friday
Mike Evans

Practicing Again Thursday
Jusuf Nurkić

Jusuf Nurkic Questionable With Rib Contusion
Marcus Smart

Sidelined Thursday Against Raptors
Los Angeles Clippers

Chris Paul Set To Part Ways With Clippers
CFB

Brian Daboll a Candidate for Penn State Head-Coaching Job?
Yves Missi

Sidelined vs. Wolves
Quentin Grimes

Uncertain To Play Against Golden State
Bilal Coulibaly

Likely Out Multiple Weeks With Oblique Strain
Karel Vejmelka

Records Impressive Shutout
JJ Peterka

Rocks Ducks With Four-Point Effort
Cole Caufield

Extends Point Streak With Power-Play Assist
Matvei Michkov

Delivers Two Assists Wednesday
Jake Oettinger

Grabs Fourth Consecutive Victory With Shutout
Ryan Leonard

Tallies Four Points in Wednesday's Win
Cam York

Exits Win Early
Jakob Poeltl

to Sit Out Thursday's Game
Alexandre Sarr

to Miss Third Straight Game Thursday
Jonathan Kuminga

Iffy for Thursday
Jimmy Butler III

Listed as Questionable for Thursday
Paul George

Questionable Thursday
Joel Embiid

Unlikely to Play Thursday
Jaylen Brown

Doubtful to Play Thursday
Kevin Huerter

Sidelined One Week
Daniel Gafford

Aggravates Right-Ankle Injury on Wednesday
Collin Sexton

Injured in Loss to Knicks
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Suffers Calf Injury on Wednesday Night
Kyren Williams

Expected to Play in Week 14
Davante Adams

Expected to Play Despite Missing Wednesday's Practice
Kyle Tucker

Visits With Blue Jays
Woody Marks

Texans Say Woody Marks Will be Fine
Rasmus Ristolainen

to Miss at Least One More Week
Drew Doughty

Logs Full Practice Wednesday
Emilio Pagán

Reds Bring Back Closer Emilio Pagan on Two-Year Deal
Jeff Skinner

Remains Sidelined Wednesday
Petr Mrazek

Out 2-3 Weeks
Pelle Larsson

Set to Suit Up Versus Dallas
Tyler Seguin

Likely Done for the Season
P.J. Washington

Ruled Out Against Miami
Neal Pionk

Returns to Jets Lineup
Jalen Smith

to Miss Third Straight Game
Duncan Robinson

Sidelined Again Wednesday
J.J. McCarthy

Practices in Full, on Track to Return in Week 14
Cedric Mullins

Rays Agree on One-Year Deal
Mark Andrews

Agrees to Three-Year Extension With Ravens
Freddy Peralta

Brewers Considering Trading Freddy Peralta
Kyle Schwarber

Reds Serious About Adding Kyle Schwarber in Free Agency?
Amon-Ra St. Brown

Officially Questionable for Thursday Night
Omarion Hampton

"on Track and Looking Good" for Week 14
CFB

Brent Key Signing Five-Year Deal to Remain at Georgia Tech
Joey Bosa

Week-to-Week With Hamstring Injury
Bryce Young

Panthers Expected to Pick Up Bryce Young's Fifth-Year Option
Deshaun Watson

Browns Opening Practice Window for Deshaun Watson
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Brian Hartline Expected to Land USF Head-Coaching Job
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Collin Klein Expected to be Top Target for Kansas State if Head-Coach Job Opens
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Chris Klieman Considering Stepping Down at Kansas State
Aaron Rodgers

Appears to be Healthier Heading into Week 14
Jalen McMillan

Expected to Have his 21-day Practice Window Opened
Mike Evans

' Practice Window Opened, Returning to Practice on Wednesday
Alexander Wennberg

a Game-Time Call Wednesday
Michael Callahan

Sustains Lower-Body Injury Tuesday
Michael Rasmussen

Makes Early Exit Tuesday
Scott Wedgewood

Exits Early With Back Problem
Evander Kane

Expected to Be Fine After Skate Cut
Tyler Seguin

Injured Versus Rangers
Sean Monahan

Expected to Play Thursday
Nathan Walker

Out for Eight Weeks
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D.J. Durkin Staying at Auburn Under Alex Golesh
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Charlie Weis Jr. Permitted to Coach Ole Miss Offense in College Football Playoff
Tyrone Tracy Jr.

Says he's Fine After Suffering Hip Contusion
Omarion Hampton

Likely to Return in Week 14
CFB

Five-Star Quarterback Jared Curtis Flips Commitment From Georgia to Vanderbilt
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Florida Hiring Brad White as Defensive Coordinator
Kyle Schwarber

Giants Have Checked in on Kyle Schwarber
Willson Contreras

Willing to Waive his Full No-Trade Clause?
Brandon Aiyuk

49ers "Hopeful" Brandon Aiyuk Will Play in 2025
Tyrone Tracy Jr.

Carted Off With Hip Injury on Monday Night
Edwin Díaz

Mets Still Interested in Re-Signing Edwin Diaz
Devin Williams

Agrees to Three-Year Deal With Mets
Cole Ragans

Red Sox Targeting Cole Ragans in a Trade?
CFB

Kentucky Hires Oregon Offensive Coordinator Will Stein As Head Coach
Davante Adams

Not Dealing With a Serious Injury
Kyler Murray

Surgery Not on the Table for Kyler Murray
CFB

Kalani Sitake the Top Target for Penn State Coaching Job
CFB

Josh Heupel Says He's Not a Candidate for Penn State Head Coach Job
CFB

Will Stein, Brian Hartline the Top Candidates for Kentucky Job?
CFB

Nebraska Fires Defensive Coordinator John Butler After One Season
CFB

UCLA Expected to Hire Bob Chesney as Next Head Coach
CFB

Lane Kiffin to Make $13 Million Salary, Ties Kirby Smart
CFB

Buster Faulkner, Joey Halzle Candidates for Florida Offensive Coordinator Job?
CFB

Kentucky Officially Fires Mark Stoops
CFB

Lane Kiffin to be Introduced as LSU's Next Head Coach on Monday
CFB

Florida Poised to Land Jon Sumrall as Next Head Coach
CFB

Alex Golesh Taking Over Auburn Head-Coaching Job
Zack Wheeler

Likely to Return in May
Ryan Helsley

Agrees to Two-Year Deal With Orioles

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