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QB vs Pass Rush Matchups To Watch - Week 16

Gage Bridgford (@GbridgfordNFL) identifies quarterbacks to watch in Week 16 based on the opposing pass rush defense. These QBs could be players to fade and avoid or to start and stream in fantasy football leagues.

Week 16 is here, and fantasy championships are on the line. Some teams head into the fantasy finals as big favorites but others are scrapping to pull off a big win as underdogs. Real teams start at quarterback, and the position is pretty important for fantasy as well.

Quarterbacks have changed the game for fantasy football this year with guys like Lamar Jackson and Josh Allen taking full advantage of their running ability to stress defenses. It gives you more viable options on a week-to-week basis.

Right now, these are the weeks that we've spent months preparing and competing for. There's no room for an error, and it's not time to get cute. We have to set our best lineups to win because we aren't coming back next week if we don't.

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

Look Away Before It Gets Ugly

Jared Goff @ San Francisco 49ers

You're telling me that Los Angeles Rams quarterback Jared Goff has to go on the road in a do-or-die game against one of the best teams in the conference. I don't like his odds. His offensive line has struggled to generate time for their quarterback despite only giving up 21 sacks this season. In the previous matchup between these two teams, Goff was taken down four times. So, one-fifth of his sacks came in one game, and that was at home.

One issue for the San Francisco 49ers Defense is that they're dealing with several injuries to their pass rush. However, they're still trotting out one of the most fearsome fronts in football from Nick Bosa to Arik Armstead and everyone in between. They have 47 sacks on the year, and, with two games remaining, they would have finished as a top-10 team in sacks last season. This group gets after the quarterback, and, in their fight for playoff seeding, they'll be wanting to make a statement on Saturday night.

 

Sam Darnold vs Pittsburgh Steelers

This Pittsburgh Steelers team is not the best in football, but, with the collection of players that they've been trotting out, they're playing far better than anyone would have expected. It's been largely on the back of their defense. They've gotten an NFL best 49 sacks thus far, and they'll likely be adding to that total in Week 16. They control their playoff destiny if they're able to win in each of the final two weeks. Week 17 isn't guaranteed against a hot Baltimore Ravens team, but they can make life a lot easier with a win this week.

New York Jets quarterback Sam Darnold has been hit a lot this year, as the team has given up 48 sacks on the season. He's also been extremely inconsistent. After seeing ghosts against the New England Patriots, he had a hot few games, but they've also lost to two winless teams (at the time) in the Miami Dolphins and Cincinnati Bengals. They're eliminated from playoff contention, and they have nothing to play for other than draft positioning. Additionally, the dynamic between him and head coach Adam Gase will be interesting to watch after their sideline blowup last week.

 

Daniel Jones @ Washington Redskins

First things first, why are the New York Giants playing Daniel Jones (ankle) despite his high ankle sprain? You just spent a first-round pick on the guy, and you're bringing him back literally two weeks after an injury that typically takes multiple weeks to recover from. This offensive line has allowed 38 sacks this season, and his mobility will likely be limited by the injury. New York just lost tight end Evan Engram (foot) for the remainder of the season, and these final two weeks will not be an amazing swan song.

The Washington Redskins have shown life in recent weeks with quarterback Dwayne Haskins under center, and their defense has also shown some improvement. They're fifth in the NFL with 42 sacks, and they want to see what they have in this rookie with the year nearly over. This is an audition for their next head coach whether that is Urban Meyer or someone else. In a battle of two terrible teams in lost seasons, I think Washington gets after Jones early and often.

 

That's More Like It

Gardner Minshew @ Atlanta Falcons

I would like Jaguars quarterback Gardner Minshew a lot more if this were a home game, but, I still like him this week. No longer under the reign of the almighty Tom Coughlin, this Jaguars team is going to come out and make a statement, and a lot of that is going to be by running the ball and throwing against an overmatched Falcons Defense. The Jaguars are in the top half of the NFL in sacks allowed. Additionally, both of his starting wide receivers are expected to be healthy for this dome contest with D.J. Chark apparently over an ankle injury that cost him the previous game.

The Falcons are led by a defensive-minded head coach, but they've been a lot more bark than bite for a few years. This season, they have just 24 sacks through 14 games. The strength of their pass rush is on the inside with stud defensive tackle Grady Jarrett, but the strength of the Jaguars offensive line is on the interior. The matchups aren't in their favor, and, in a sneaky shootout, the odds favor the Jaguars in this one.

 

Kyler Murray @ Seattle Seahawks

Arizona Cardinals quarterback Kyler Murray has performed about as well as one could have hoped entering the year. He has used his running ability to keep his fantasy floor high, and, despite playing behind a struggling offensive line, he gets the ball out to his receivers. The team is averaging about 22 points per game, and they're going to be forced to score a lot against one of the NFL's top-10 offenses.

Thankfully for Murray and Arizona, the Seahawks don't have the fierce pass rush that they had earlier in the decade. They have just 24 sacks this season, and they're giving up over 24 points per game. This defense allows points, and the offense is often tasked with bailing them out. Murray will find his opportunities to score despite his offensive line's struggles.

 

Drew Lock vs Detroit Lions

Fading the Detroit Lions Defense has been a good strategy for most of the year. They don't have any form of a pass rush, and their secondary, outside of veteran cornerback Darius Slay, can't cover anyone. Drew Lock came back to earth last week against a sneaky good Kansas City Chiefs Defense, but he has the matchup to rebound this week. His offensive line has only allowed three sacks in the three games he has played, and the Lions aren't the type of group that could drastically increase that total.

The Lions have 27 sacks this season with 14.0 of those sacks coming from two players in the forms of Trey Flowers and Devon Kennard. Outside of those two, the next-highest player on the team has just two. If Denver can slow down those two, it's going to be next to impossible for Detroit to generate any pressure. Lock isn't an ideal play, but he's far from the worst on this week's slate.

More Weekly Lineup Prep




REAL-TIME FANTASY NEWS

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Orioles-Tigers Game Postponed on Saturday
RJ Harvey

to be Relegated to Third-Down Role After Rookie RB Addition?
Baker Mayfield

A Lot of Uncertainty Surrounding Baker Mayfield Going into Fourth Year in Tampa
Brian Robinson Jr.

a Must-Have Handcuff in Dynasty Leagues?
Sam LaPorta

Could be Excellent Buy-Low Candidate for Risk-Tolerant Managers
Jordyn Tyson

on a "Maintenance Plan" During Offseason Workouts
Kenneth Walker III

One of Dynasty's Biggest Risers for 2026
D'Andre Swift

an Underappreciated Dynasty Buy Candidate
Ray Davis

Still a Dynasty Stash Despite a Lack of Standalone Value
Travis Kelce

Now a Low-Cost Dynasty Rental
DJ Moore

a Reasonable Buy Candidate Now That Dynasty Market Has Cooled
MLB

Rays-Yankees Postponed on Saturday
Devin Vassell

Posts 20 Points in Game 3 Loss
De'Aaron Fox

Struggles From Deep in Friday's Loss
Victor Wembanyama

Held to Four Rebounds in Game 3 Loss
Jaylin Williams

Catches Fire From Deep Friday
Jared McCain

Drops Playoff-High 24 Points in Game 3
Nazem Kadri

Contributes an Assist in Losing Effort
Shai Gilgeous-Alexander

Guides Thunder to 2-1 Series Lead
Ajay Mitchell

Does Not Return in Game 3 Win
Ross Colton

Nets Lone Avalanche Goal Friday Night
Rasmus Andersson

Extends Assist Streak to Four Games
Pavel Dorofeyev

Focuses on Playmaking in Friday's Win
Jack Eichel

Enjoys Multi-Point Outing in Game 2 Win Friday
Ivan Barbashev

Amasses Three Points as Golden Knights Grab 2-0 Series Lead
Jordan James

Most Likely to be 49ers' RB2 in 2026
Mickey Moniak

Heads to Injured List With Ankle Sprain
Rudy Gobert

Earns Eighth All-Defensive First-Team Selection
Victor Wembanyama

Headlines 2025-26 All-Defensive First Team
Ajay Mitchell

Starting Game 3 Against Spurs
Dylan Harper

Available for Game 3 Against Thunder
De'Aaron Fox

Returns to Action Friday
Jalen Williams

Won't Play Friday Night
Derrick Henry

Remains in RB1 Discussion
Ladd McConkey

is Solid Buy-Low Candidate
Ryan Flournoy

an Intriguing Dynasty Stash Option
Jalen Nailor

is Expected to Have Larger Role in Las Vegas
Frederik Andersen

Hurricanes Keep Faith in Frederik Andersen
Devon Levi

Attracting Interest From Senators
Jacoby Brissett

Cardinals Not Close to a Reworked Deal
Scott Wedgewood

Starting Game 2 Against Golden Knights
Ben Hutton

Scratched for Game 2 Against Avalanche
Mark Stone

Won't Play Friday
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
Cale Makar

Remains Out Friday
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
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Jadan Baugh Primed to Lead Florida Offense in 2026
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LSU Hires Ed Orgeron As Special Assistant
NFL

Evan Stewart Pushing Oregon Receiving Corps
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
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Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
New York Giants

Giants, GM Joe Schoen Agree on a Multi-Year Extension
Andrew Thomas

Giants Managing Multiple Injuries for Andrew Thomas
Cam Ward

Loses 10 Pounds in the Offseason
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Tucker Kraft

a Top Trade Target in Dynasty Leagues?
Evan Mobley

Fills the Box Score in Game 2 Loss
James Harden

Held to Two Assists Thursday
Donovan Mitchell

Leads Cavaliers in Scoring in Game 2 Defeat
Karl-Anthony Towns

Records Double-Double in Game 2 Win
Sebastian Aho

Picks Up an Assist in Series-Opening Loss
Mikal Bridges

Adds 19 Points as Knicks Grab 2-0 Lead
Jalen Brunson

Hands Out 14 Assists in Game 2 Win
Seth Jarvis

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Josh Hart

Erupts for Playoff Career-High 26 Points in Game 2
Jaccob Slavin

Struggles in Game 1 Against Canadiens
Jakub Dobes

Sharp in Game 1 Victory
Cole Caufield

Bags Two Points in Impressive Road Win
Juraj Slafkovsky

Opens Conference Finals With Three-Point Performance
Nick Suzuki

Notches Three Assists in Game 1 Win Over Hurricanes
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Jrue Holiday

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Alex Tuch

Hopes to Remain in Buffalo
Sidney Crosby

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Robby Snelling

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Jackson Merrill

Tweaks his Back on Wednesday, Pulled Early
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Lincoln Riley Believes USC is Ready for Playoff Run
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Notre Dame-Stanford Rivalry Renewed Through 2028
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Ahmad Hardy Says He's "Back to the Road to Success"
CFB

Texas Tech Graduate Judge Recuses Himself from Brendan Sorsby Case
CFB

UCLA Tackle Jordan Davis Officially Eligible for 2026 Season
CFB

Bret Bielema Supports Significant College Football Playoff Expansion
Michael Thorbjornsen

Brings High Upside to CJ Cup Byron Nelson
Luke List

Carrying Poor Form Into CJ Cup Byron Nelson
Tom Kim

Hoping to Build on Strong Myrtle Beach Finish
PGA

Sungjae Im Brings Upside to TPC Craig Ranch
Billy Horschel

Looking for Turnaround at CJ Cup Byron Nelson
Adam Hadwin

Difficult to Trust at TPC Craig Ranch
Tony Finau

Looking for Consistency at TPC Craig Ranch
Luke Clanton

Searching for Form at CJ Cup Byron Nelson
Aaron Rai

Withdraws From CJ Cup Byron Nelson
Wyndham Clark

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Si Woo Kim

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Scottie Scheffler

to Defend CJ Cup Byron Nelson Title This Week
Jordan Spieth

Looking For Victory at TPC Craig Ranch
PGA

Matti Schmid Looks to Keep Recent Momentum Going at TPC Craig Ranch
Brooks Koepka

a High-Upside Play at CJ Cup Byron Nelson
Yandy Díaz

Yandy Diaz Exits Early on Tuesday After Being Hit By Pitch
Chris Kirk

Continues Search For Putting Form at TPC Craig Ranch
Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
Joel Dahmen

is of No DFS Consideration This Week in Dallas
Pierceson Coody

is Not The Fun DFS Play He Used to Be
Gerrit Cole

to Make Season Debut on Friday Against Rays
Drake Baldwin

Braves Place Drake Baldwin on Injured List With Oblique Strain
CFB

Ezavier Crowell has Immediate Opportunity at Alabama
CFB

Mark Bowman a Day 1 Impact Player for USC?
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Bill Belichick Says Relationship with First North Carolina Team "Wasn't Great"
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Kemario Taylor a Breakout Candidate at Quarterback
CFB

Trinidad Chambliss the Undisputed Top SEC Quarterback Entering 2026?
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Rocco Becht The "Unifier" of Penn State's Roster
Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Corey Seager

Going on Injured List With Back Injury
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Melquizael Costa

Drops Decision At UFC Vegas 117
Arnold Allen

Bounces Back
Daniel Santos

Suffers Second-Round TKO Loss
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
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1B
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OF
SP
RP

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