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Updated Week 6 Flex Rankings (Top 200)

Our updated Week 6 fantasy football Flex rankings (RB, WR, TE) for 2021. Follow these fantasy football FLEX ranks when setting your Week 6 lineups.

Welcome to Week 6 RotoBallers. Below are our updated consensus Week 6 Flex rankings for fantasy football, including some running notes on relevant injuries, player news and rankings updates. These Flex rankings are geared towards making decisions for your Flex spot (RB/WR or RB/WR/TE), which in most leagues consists of running backs, wide receivers and in many cases tight ends as well:

These rankings are a consensus from four of our lead fantasy football columnists - Nick MarianoPierre Camus, Brandon Murchison and Scott Engel - who have all analyzed the NFL matchups and game slates for Week 6.

And in case you weren't aware, our very own Nick Mariano was ranked #11 overall in 2018 out of ~120 industry experts, and was ranked #9 overall the year before. So be sure to follow his rankings every week!

Be sure to check all of our fantasy football rankings for 2025:

 

Week 6 Fantasy Football Flex Rankings

You can also see our full Week 6 ranks for PPRHalf-PPR and Standard scoring.

Last updated on Sunday 10/17 at 11:00 am ET:

FLEX Rank Player Name Pos
1 Derrick Henry RB
2 Davante Adams WR
3 Austin Ekeler RB
4 Jonathan Taylor RB
5 Stefon Diggs WR
6 Najee Harris RB
7 Travis Kelce TE
8 Tyreek Hill WR
9 Kareem Hunt RB
10 Cooper Kupp WR
11 Ezekiel Elliott RB
12 James Robinson RB
13 Aaron Jones RB
14 Justin Jefferson WR
15 DeAndre Hopkins WR
16 D'Andre Swift RB
17 Ja'Marr Chase WR
18 D.J. Moore WR
19 Terry Mclaurin WR
20 Keenan Allen WR
21 D.K. Metcalf WR
22 Joe Mixon RB
23 Diontae Johnson WR
24 Antonio Gibson RB
25 Dalvin Cook RB
26 Mike Williams WR
27 Robert Woods WR
28 CeeDee Lamb WR
29 Chris Godwin WR
30 Darrell Henderson Jr. RB
31 Courtland Sutton WR
32 Mike Evans WR
33 DeVonta Smith WR
34 Chase Claypool WR
35 Marquise Brown WR
36 Michael Pittman Jr. WR
37 Antonio Brown WR
38 A.J. Brown WR
39 Adam Thielen WR
40 Amari Cooper WR
41 Mark Andrews TE
42 Leonard Fournette RB
43 Chuba Hubbard RB
44 Dawson Knox TE
45 Brandin Cooks WR
46 Tyler Lockett WR
47 Josh Jacobs RB
48 Myles Gaskin RB
49 Emmanuel Sanders WR
50 Darren Waller TE
51 Devontae Booker RB
52 Tee Higgins WR
53 Tyler Boyd WR
54 Khalil Herbert RB
55 Kadarius Toney WR
56 Jakobi Meyers WR
57 Chase Edmonds RB
58 Jaylen Waddle WR
59 Darrel Williams RB
60 Zack Moss RB
61 Marvin Jones Jr. WR
62 Julio Jones WR
63 Sterling Shepard WR
64 Damien Harris RB
65 Melvin Gordon III RB
66 Javonte Williams RB
67 Allen Robinson II WR
68 Amon-Ra St. Brown WR
69 Dalton Schultz TE
70 Odell Beckham Jr. WR
71 Tim Patrick WR
72 Latavius Murray RB
73 Noah Fant TE
74 Mecole Hardman WR
75 Tony Pollard RB
76 Laviska Shenault Jr. WR
77 T.J. Hockenson TE
78 Mike Gesicki TE
79 Rondale Moore WR
80 Darnell Mooney WR
81 Alex Collins RB
82 Hunter Henry TE
83 Cole Beasley WR
84 Hunter Renfrow WR
85 Jamaal Williams RB
86 Zach Ertz TE
87 Henry Ruggs III WR
88 Robby Anderson WR
89 Christian Kirk WR
90 James Conner RB
91 Quez Watkins WR
92 Alexander Mattison RB
93 J.D. McKissic RB
94 AJ Dillon RB
95 Jalen Reagor WR
96 Tyler Higbee TE
97 Kendrick Bourne WR
98 A.J. Green WR
99 Ricky Seals-Jones TE
100 Devin Singletary RB
101 Nyheim Hines RB
102 Van Jefferson WR
103 Kenneth Gainwell RB
104 Bryan Edwards WR
105 Nelson Agholor WR
106 Miles Sanders RB
107 Jared Cook TE
108 Dan Arnold TE
109 Randall Cobb WR
110 Rashod Bateman WR
111 David Njoku TE
112 Kalif Raymond WR
113 Sony Michel RB
114 DeSean Jackson WR
115 Donovan Peoples-Jones WR
116 David Johnson RB
117 Terrace Marshall Jr. WR
118 Adam Humphries WR
119 Zach Pascal WR
120 Cedrick Wilson Jr. WR
121 K.J. Osborn WR
122 Evan Engram TE
123 Allen Lazard WR
124 Tyler Conklin TE
125 Jonnu Smith TE
126 Gabriel Davis WR
127 Preston Williams WR
128 Robert Tonyan TE
129 Brandon Bolden RB
130 Giovani Bernard RB
131 Chris Evans RB
132 Demarcus Robinson WR
133 Darius Slayton WR
134 Cameron Brate TE
135 Malcolm Brown RB
136 DeAndre Carter WR
137 Gerald Everett TE
138 C.J. Uzomah TE
139 Cole Kmet TE
140 Rashard Higgins WR
141 Chris Conley WR
142 Mark Ingram II RB
143 Kenyan Drake RB
144 Josh Reynolds WR
145 Tavon Austin WR
146 Jeremy McNichols RB
147 Austin Hooper TE
148 Mo Alie-Cox TE
149 Chester Rogers WR
150 James Washington WR
151 Anthony Firkser TE
152 Ray-Ray McCloud WR
153 Jerick McKinnon RB
154 Parris Campbell WR
155 Freddie Swain WR
156 John Ross WR
157 Ronald Jones II RB
158 Devin Duvernay WR
159 Demetric Felton WR
160 Byron Pringle WR
161 Jamal Agnew WR
162 Jack Doyle TE
163 Marlon Mack RB
164 Carlos Hyde RB
165 Jalen Guyton WR
166 Blake Jarwin TE
167 Cameron Batson WR
168 Eric Ebron TE
169 Collin Johnson WR
170 Pat Freiermuth TE
171 Greg Ward WR
172 Rhamondre Stevenson RB
173 Trinity Benson WR
174 Chris Moore WR
175 Marcus Johnson WR
176 KhaDarel Hodge WR
177 Kendall Hinton WR
178 Salvon Ahmed RB
179 Albert Wilson WR
180 Donald Parham Jr. TE
181 Anthony Schwartz WR
182 D'Ernest Johnson RB
183 N'Keal Harry WR
184 Tyler Johnson WR
185 O.J. Howard TE
186 Zay Jones WR
187 Demetrius Harris TE
188 Josh Gordon WR
189 James Proche II WR
190 Auden Tate WR
191 Tommy Tremble TE
192 Ian Thomas TE
193 Devonta Freeman RB
194 Ashton Dulin WR
195 Larry Rountree III RB
196 Kyle Rudolph TE
197 Ty'Son Williams RB
198 Will Dissly TE
199 Pharaoh Brown TE
200 Jordan Akins TE


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More Weekly Lineup Prep


Check out all of RotoBaller's fantasy football rankings. Staff rankings are updated regularly for all positions and include standard formats, PPR scoring, tiered rankings and dynasty leagues.




POPULAR FANTASY TOOLS

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REAL-TIME FANTASY NEWS

Rome Odunze

Bears Optimistic Rome Odunze Will Play in Week 15
CFB

LaNorris Sellers to Return to South Carolina in 2026
Cason Wallace

Off Injury Report Saturday
Keyonte George

Erupts for Career-High 39 Points Against Memphis
Bones Hyland

Exits Early With Knee Contusion
Isaiah Joe

To Miss Fourth Straight Game
Isaiah Hartenstein

Removed From Injury Report
Austin Reaves

To Be Re-Evaluated In One Week With Calf Strain
Logan O'Connor

Still Not Ready for Season Debut
Lukas Dostal

Activated From Injured Reserve
NJ

Arseni Gritsyuk Ruled Out for Weekend's Action
Connor Bedard

Ruled Out for Saturday
Zeev Buium

Canucks Acquire Zeev Buium From Wild
Marco Rossi

Moves to Vancouver
Quinn Hughes

Traded to WIld
Joel Embiid

Available Against Indiana
Ja Morant

Back on Friday Night
Rickard Rakell

Available Saturday
Tre Jones

is Returning on Friday
Coby White

Cleared for Action Versus Hornets
Jake Ferguson

Listed as Questionable for Week 15
Bo Horvat

Ruled Out for Saturday
Tre Johnson

to be Limited in Return on Friday
Andrei Vasilevskiy

Could Return Monday
Geno Smith

Officially Ruled Out for Week 15
Victor Hedman

to Be Out Until February
Kenny Pickett

to Start in Week 15 Against Eagles
Moussa Diabaté

Moussa Diabate Available on Friday
Jared McCann

to Miss Three Weeks With Lower-Body Injury
Tyrese Maxey

Under the Weather on Friday
Josh Jacobs

Officially Questionable to Face the Broncos
Victor Wembanyama

Expected to Return on Saturday
Stuart Skinner

Shipped to Pittsburgh
Tristan Jarry

Oilers Acquire Tristan Jarry From Penguins
Anthony Edwards

Sidelined on Friday Evening
Deebo Samuel Sr.

Questionable for Week 15
CFB

Washington State Expected to Hire Kirby Moore as Next Head Coach
CFB

Kyle Whittingham Stepping Down as Utah Head Coach
T.J. Watt

Officially Ruled Out for Monday Night
Manel Kape

Set For UFC Vegas 112 Main Event
Davante Adams

to be Questionable, Expected to Play on Sunday
Brandon Royval

An Underdog At UFC Vegas 112
Rome Odunze

Questionable for Sunday
Kevin Vallejos

Set For His Third UFC Fight
Alvin Kamara

Ruled Out for Sunday
Giga Chikadze

In Dire Need Of Victory
Cesar Almeida

Set To Welcome Cezary Oleksiejczuk To The UFC
Cezary Oleksiejczuk

Set To Make His UFC Debut
Jayden Daniels

Not Cleared for Contact
T.J. Watt

Undergoes Surgery for Collapsed Lung
Maikel Garcia

Royals Agree on Five-Year Extension
Melquizael Costa

Looks To Extend His Win Streak
Morgan Charrière

Morgan Charriere Looks to Win Second Consecutive Fights
Marcus Buchecha

Looks To Bounce Back
Kennedy Nzechukwu

A Favorite At UFC Vegas 112
King Green

Returns At UFC Vegas 112
Lance Gibson jr

Lance Gibson Jr. Set To Open Up UFC Vegas 112 Main Card
Jake Ferguson

on Track to Play in Week 15
CFB

Sherrone Moore Charged with Home Invasion, Among Other Charges
Jayden Daniels

Cleared for Contact
Tee Higgins

Ruled Out Against Ravens
Marvin Harrison Jr.

Ruled Out for Week 15, Expected Back This Year
Josh Jacobs

"Feeling Pretty Good," Will Practice on Friday
Daniel Gafford

Still Unlikely to Play Friday
Brady Cook

to Get Starting Nod for Jets in Week 15
Khris Middleton

Misses Second Straight Game
Collin Sexton

Sidelined Again Versus Bulls
Tee Higgins

Absent From Practice on Friday
Coby White

On Track To Suit Up Versus Charlotte
De'Von Achane

Should Be Available Monday
Tre Jones

Expected To Play Friday Vs. Hornets
Los Angeles Chargers

Chargers to Utilize Hot-Hand Approach in Backfield Moving Forward?
Ayo Dosunmu

to Miss Friday's Game Vs. Hornets
CFB

Freddie Kitchens Fired from North Carolina Coaching Staff
Joel Kiviranta

Hurt in Thursday's Win
Lars Eller

Departs Early Versus Blue Jackets
Viktor Arvidsson

Makes Early Exit Against Jets
Bo Horvat

Suffers Lower-Body Injury in Thursday's Win
Oliver Ekman-Larsson

Sustains Lower-Body Injury
Roope Hintz

Exits Loss With Injury
Logan Cooley

to Miss at Least Eight Weeks
CFB

Bryce Underwood Could Leave Michigan Without Buyout
Fernando Tatis Jr.

Padres Not Considering Trading Fernando Tatis Jr.
Tarik Skubal

Tigers Engaged in "Serious Talks" Around Trading Tarik Skubal at the Winter Meetings
CFB

Chris Brazzell II Declaring for NFL Draft
CFB

Fernando Mendoza Named AP College Football Player of the Year
Raisel Iglesias

to Remain the Braves Closer
Robert Suarez

Agrees on Three-Year Deal With Braves
CFB

Sherrone Moore Remains in Police Custody
CFB

Joe Klanderman Joining Baylor Coaching Staff
CFB

Kentucky Hiring Jay Bateman as Next Defensive Coordinator
Si Woo Kim

Closes 2025 With Strong Finish Among Putting Woes
Akshay Bhatia

Looks to Rebound in 2026 After Down Year Off the Tee
Brian Harman

2025 Season a Step Back Despite Spring Win
Sam Burns

' Elite Putting Headlines a Solid 2025 Season
Sepp Straka

Ends Stellar 2025 Campaign on a High Note
Robert MacIntyre

Closes Out a Steady 2025 Campaign
CFB

Chip Kelly Interviews for Georgia Tech Offensive Coordinator Job
CFB

Louisville Receiver Chris Bell has a Torn ACL
Min Woo Lee

Breaks Through to Win in Texas This Year
PGA

Alex Noren Wins Twice on European Tour This Year
Wyndham Clark

has Up-and-Down 2025 Golf Season
CFB

Michigan Fires Head Coach Sherrone Moore
Corey Conners

Comes Close to Winning Again in Very Good 2025
Justin Rose

Turns Back the Clock in 2025
CFB

Jim Knowles Expected to be Hired as Tennessee's Defensive Coordinator
Harris English

Enjoys Solid Finish at Hero World Challenge
CFB

Defensive Coordinator Jim Knowles Not Being Retained at Penn State
CFB

Indiana's Stephen Daley Done for Season After Post-Game Injury
Pete Alonso

Orioles Finalizing Five-Year Deal
Kyle Finnegan

Tigers, Kyle Finnegan Agree on Two-Year Deal
Bo Bichette

Red Sox Out on Bo Bichette For Now
Philadelphia Phillies

Phillies Extend Manager Rob Thomson Through 2027 Season
Michael King

the Mets' Top Rotation Target?
Ronald Acuña Jr.

Ronald Acuna Jr. Could Move Back to Leadoff Spot
CFB

Florida, Wisconsin Among Suitors for QB Transfer Kenny Minchey
CFB

Bryan Harsin, Justin Wilcox Candidates for Washington State Head Coach Job?
Edwin Díaz

Edwin Diaz Agrees to Deal With the Dodgers
Kyle Schwarber

Returning to Phillies on Five-Year Deal
CFB

Ole Miss Hiring John David Baker as Offensive Coordinator
CFB

Ty Howle the Top Target for Virginia Tech Offensive Coordinator Job
Shohei Ohtani

to be Used More as Traditional Starting Pitcher Next Year
Yordan Alvarez

to Become Full-Time DH in 2026?
Mason Miller

Padres Plan to Keep Mason Miller in the Bullpen
Ranger Suárez

Orioles Interested in Signing Ranger Suarez
Anthony Volpe

Yankees Don't Expect Anthony Volpe to be Ready in April
Gerrit Cole

Targeting a Return in May/June
Rory McIlroy

Ends 2025 as the Year's Most Unburdened Player
Aaron Rai

Needs to Figure Out Putting Woes This Offseason
Jordan Spieth

Plays Better on Paper in 2025 Than Results Show
PGA

Chris Gotterup Needs to Find Better Touch and Consistency This Offseason
Hideki Matsuyama

Ends 2025 Season With a Bookend Victory
Scottie Scheffler

Comes Up Just Shy of Hero World Challenge Victory
Merab Dvalishvili

Drops A Decision At UFC 323
Petr Yan

Reclaims Bantamweight Title
Alexandre Pantoja

Era Ends With Gruesome Injury
Joshua Van

Becomes Second-Youngest UFC Champion
Brandon Moreno

Suffers His First TKO Loss
Brandon Moreno

Tatsuro Taira Becomes First Fighter To Finish Brandon Moreno
Henry Cejudo

Payton Talbott Retires Henry Cejudo
Henry Cejudo

Retires After UFC 323 Loss
Jan Blachowicz

Bogdan Guskov Vs. Jan Blachowicz Ends In A Majority Draw
San Francisco Giants

Jeff Kent Elected to Baseball Hall of Fame
Ketel Marte

Red Sox Interested in Trading for Ketel Marte

RANKINGS

QB
RB
WR
TE
K
DEF
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP