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San Francisco 49ers running back Christian McCaffrey (calf) recently landed on the injury report this week. McCaffrey seemed fine throughout training camp and the preseason, but now is dealing with a calf injury just days before the season opener. It's worth noting that McCaffrey missed a portion of last season due to a lingering calf issue. According to Tom Pelissero, McCaffrey's absence shouldn't be ringing any alarm bells. Obviously, the 49ers are going to be cautious with McCaffrey if he's feeling any discomfort at all. At the moment, there is no word on the significance of the injury, so it could be very minor. There is no reason to believe that McCaffrey won't be out there for the season opener. If he does miss time, Brian Robinson Jr. and Isaac Guerendo would function as the primary options in the backfield.--Andy Webb
Source: Tom Pelissero
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