👉 TAP TO SAVE 50% WITH CODE SPRING
X
Lost password?

Don't have an account?
Gain Access Now

X

Receive free daily analysis

NFL
NBA
NHL
NASCAR
CFB
MLB
MMA
PGA
ESPORTS
BETTING

Already have an account? Log In

X

Forgot Password


POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

Week 10 Start/Sit: Monday Night Football Matchup Analysis

Fantasy football start 'em, sit 'em for MNF - Week 10. Monday Night Football matchups analysis and fantasy start/sit advice for New York Giants at San Francisco 49ers

For some, it's birth. Other's may come in the form of an experience. There are even those few (my aunt) who fall in that weird, I just like their colors category. But, every sports fan has that defining moment which determines "their team". Mine came January 27, 1991 - the infamous Scott Norwood, "wide right" Super Bowl XXV. At six-and-a-half years old, I didn't know much about football -- other than it was fun to play outside with my friends and hurt sometimes -- but, my dad did. My Giants fan dad, that is, and the celebration which ensued following Norwood's botch job is one of the more memorable moments of my early childhood.

I could go into more detail, and turn this into an emotional trip down memory lane, but that's not what I'm going for here. I bring all of this up simply because that Super Bowl victory would not have been possible had the Giants not gone into Candlestick Park a week prior, kicked a million field goals, and defeated the two-time defending champion San Francisco 49ers... In their house (in case you're too young for the Candlestick reference). This was a different time. The Giants were actually good at playing football; as were the 49ers. No longer is this the case. And, when the (1-7) New York Giants head to Santa Clara to face the (2-7) San Francisco 49ers, a trip to the Super Bowl will not be at risk - they'll be playing for draft position.

This game might not have any playoff implications, and the reality is, losing would actually offer more long-term benefit. However, it's only Week 10 and these are prideful men who have a job to do - don't expect them not to come out and play. My job, then, becomes to fill you in on who you should have in your fantasy football lineups and why you should do so. Which is exactly what you'll find below. (Reading, required. Watching, optional.)

Editor's Note: The FFPC Baby Gorilla Tournament is now open, featuring a $100,000 grand prize and a $675,450 total prize pool! This 12-team, Tight End Premium contest uses a 20-round draft format, with the overall winners determined by total points scored during Weeks 15–17. Get $25 to use toward your first entry by signing up through our link. Grab your team now! Sign Up Now!

 

New York Giants at San Francisco 49ers

Date and Start Time: Monday, November 12th at 8:15 p.m. EST
Game Spread: SF -3
Over/Under: 44
Notable Injuries and Status:

Offensive and Defensive Rankings (per game):

Giants 49ers
Passing Yards 9th 25th
Rushing Yards 31st 4th
Pass Defense 16th 17th
Run Defense 23rd 12th

 

Must Starts

Top Players That You Should Have In Your Lineup

Saquon Barkley (RB, NYG)

He's third among running backs in scrimmage yards. His 84.1-percent carry share (RB carries only) sits fourth at the position. He sees more targets per game than all but 13 wide receivers. He's also very good at playing football.

Odell Beckham Jr. (WR, NYG)

If you checked out that nifty table above, you probably saw that 9th next to passing yards per game, under Giants, and thought that must be a typo. It's not. In fact, Beckham's 98.1 receiving yards per game rank 6th among wide receivers. Problem is, Eli Manning has thrown just eight touchdown passes this season. (So too has Ryan Tannehill - he hasn't played since Week 5.) The 49ers have given up 11 receiving TDs to opposing WRs this season (tied for the sixth-most) so if there's a game to bet on OBJ finding the end zone, this is the one. If not, well, he's gone over 100 yards in five of his eight games.

 

Must Sits

Players To Avoid Putting In Your Lineup

Alfred Morris (RB, SF)

Remember when Jerick McKinnon went down in the preseason and everyone was all, "Alfred Morris is the man..."? That was cute. (I may, or may not, have endorsed Alf.) Not even the season-ending injury to Raheem Mostert justifies Morris being in your lineup at this point. He saw seven carries last week; he put up 13 yards. The Giants allowed 162 rushing yards in their first game without Damon Harrison, and Morris is likely to see some additional run by default, he just hasn't been effective enough at any point this season to trust that he'll capitalize on the opportunity/matchup. If he balls out on your waiver wire (he shouldn't even be on your bench) so be it... I've now seduced myself into considering rolling the dice on him in a DFS contest.

Marquise Goodwin (WR, SF)

There's one guy every week who's not really a must-sit. Not really a solid start either. But, has fantasy relevancy nonetheless. This week, that title is held by Marquise Goodwin, and I have no idea what to do with him. On one hand, Nick Mullens looked incredible. On the other hand, they played Oakland. On the other hand, Mullens attempted only 22 passes. And on the other, only four of them targeted Goodwin - he caught one for 11 yards. The Giants secondary has actually been decent, and I don't trust him. So, yeah. (see Pierre Garcon below)

Solid Options/Sleepers

Which Players Will Have Solid Games and Which Could Surprise?

Solid Option - Matt Breida (RB, SF)

Battling injury the past few weeks, Breida will have rested a full 10 days by the time this one kicks off - the Thursday night game followed by a Monday night'er couldn't have come at a better possible time. As mentioned, the Giants run D looked soft in their first game without Damon Harrison -- they're also dealing with some injuries on the linebacking front -- so Breida should be good for RB2 numbers (at a minimum) in this one... If he can stay on the field.

Solid Option - Sterling Shepard (WR, NYG)

Like Beckham, Shepard has fallen victim to Manning's allergy to throwing passes to receivers which are running (possibly standing) in the portion of the field which is painted a color that's typically not green and includes a word which delivers the home team's moniker. He does, however, offer value in this matchup due to the more than seven targets he sees per game and the fact that, again, San Fran has been rather generous in handing out receiving TDs to opposing WRs.

Solid Option - George Kittle (TE, SF)

Travis Kelce and Zach Ertz are the only tight ends averaging more receiving yards per game than Kittle's 76.9 - he's been balling. Thing is, the Giants held Ertz to 43 yards in Week 6, and only two TEs (Josh Hill and Jordan Thomas) have gone over 50 yards against this defense on the season. The 53.6 yards per game they've allowed to the position falls around the median, but another huge game from Kittle doesn't seem likely - the Giants are one of just five teams to have allowed one or fewer receiving TDs to the TE position as well. Still, 66.7-percent of Kittle's games this season have resulted in a Top-10 fantasy performance, so while the matchup might not be the greatest -- and he's dealing with a "chest" injury -- he should put up solid numbers.

Sleeper - Eli Manning/Nick Mullens (QB)

I do not believe that either of these quarterbacks has Top-10 potential. I also do not believe the final score will be 15-13 like the aforementioned 1991 NFC Championship game. Mullens was all of the rage following his impressive Week 9 debut, but when you consider that he became just the 10th QB this season to attempt 25 or fewer passes and finish the game with at least 20 fantasy points... He played Oakland. As mentioned, Eli puts up yardage, he just doesn't throw touchdowns. Both defenses have been almost identical against QBs (below) -- neither of which is overly dominant -- so I could see either QB having a decent game. I could also see them disappointing. They're in that Marquise Goodwin realm; low-end, 2-QB league options with minimal upside.

Sleeper - Pierre Garcon (WR, SF)

It's been a season to forget for Pierre Garcon. For everyone else, it's been more like forget Pierre Garcon. That was until Nick Mullens emerged from the depths of the underworld and contributed to Garcon's second-highest yardage total of 2018 -- as well as his first TD -- in the first quarter of last week's game against Oakland. The first quarter. Garcon disappeared after that, but here's to hoping it was a sign of things to come. Mullens didn't fare well on passes farther than 10 yards, and his average depth of target was just 6.6 yards (Derek Carr-ish) which tells me this Mullens-Garcon connection might wind up being something special (Garcon isn't exactly a deep-threat at this stage of his career).

Side Note: Garcon did not practice on Thursday.

Sleeper - Evan Engram (TE, NYG)

Engram is like that artist that drops a debut album so fire that you pre-order the sophomore project the moment it comes available. Then, you get the second album, and it's kinda weak but you're convinced that it can't be based on the debut so you force yourself to find reasons to like it. The reasons, in Engram's case, are the 5.2 targets per game (he saw nine last week) and the fact that he's been injured; he has to be getting healthier with each passing week, right? San Fran has allowed four receiving TDs to the TE position (tied for the eighth-most) so if Eli takes his Claritin, maybe there's a chance?

More Fantasy Football Analysis




POPULAR FANTASY TOOLS

Expert Advice
Articles & Tools
Import Your Leagues
Draft Rankings
Draft Simulator
Compare Any Players
24x7 News and Alerts

REAL-TIME FANTASY NEWS

Si Woo Kim

Struggles at Truist Championship
Gary Woodland

Can Continue Incredible 2026 Season at PGA Championship
Xander Schauffele

In Excellent Form Heading to PGA Championship
Jon Rahm

Having Excellent Season On LIV Tour
Collin Morikawa

Looking For Bounce Back at PGA Championship
Viktor Hovland

Struggling to Find Early Season Form Heading to PGA Championship
Matt Fitzpatrick

Looks to Bounce Back After Worst Finish of 2026
Patrick Cantlay

Showing Signs of Life After Slow Start to 2026 Season
Ludvig Aberg

Finishes Inside Top-10 Again
Rickie Fowler

Looks to Stay Hot at PGA Championship
Jason Day

Brings Boom-or-Bust Potential to PGA Championship
Jacob Bridgeman

Searching for Momentum at PGA Championship
Cade Klubnik

Becoming Fan Favorite, in Play to Win Backup QB Job?
Michael Penix Jr.

Throwing During Offseason Program
Bryce Young

Panthers Will Continue to Discuss Extension With Bryce Young
Cameron Young

Looks to Win First Career Major This Week at Aronimink
Justin Rose

Looks to Contend at Another Major Championship
Rory McIlroy

Among the Favorites This Week at Aronimink
Brandon Nimmo

Leaves Game on Tuesday with Apparent Ankle Injury
Michael Mayer

More Opportunities Coming for Michael Mayer?
Brooks Koepka

Hoping Good Vibes Travel to Year's Second Major
Chris Gotterup

Needs an Accurate Driving Week For Success at PGA Championship
Philadelphia 76ers

76ers Part Ways With Daryl Morey
Kevin Huerter

Iffy for Game 5 Against Cavaliers
Dylan Harper

Cleared for Action Tuesday
De'Aaron Fox

Available for Game 5 Against Timberwolves
Caris LeVert

Remains on Injury Report With Heel Issue
Duncan Robinson

Listed as Questionable for Game 5
Brandon Clarke

Dies at Age 29
Charlie McAvoy

Slapped With Six-Game Suspension
Jonas Brodin

Unavailable for Game 5 Against Avalanche
Joel Eriksson Ek

to Remain Out Wednesday
Sam Malinski

Day-to-Day With Upper-Body Injury
Jacob Wilson

A's Place Jacob Wilson on Injured List With Shoulder Subluxation
Artturi Lehkonen

Considered Day-to-Day
Charlie Coyle

Lands Six-Year Extension
Ukko-Pekka Luukkonen

to Start Game 4 Against Canadiens
Drew Helleson

Unavailable for Game 5
Radko Gudas

Still Out Tuesday
Mark Stone

Won't Play Tuesday
Carnell Tate

Is Carnell Tate Poised for Immediate Stardom in Tennessee?
Jeremiyah Love

Will Jeremiyah Love See a Limited Role in Arizona as a Rookie?
Wan'Dale Robinson

Dynasty Stock Fading Following NFL Draft
Bucky Irving

Not Yet Cleared to Participate in OTAs
Tyler Shough

Dynasty Stock Rising with Improved Supporting Cast in New Orleans
Garrett Wilson

Dynasty Upside Limited by Quarterback Questions
Christian Yelich

Brewers Reinstate Christian Yelich From Injured List
Ted Hurst

Viewed as "True X" Receiver Going into Rookie Campaign
Kenneth Gainwell

Zac Robinson Thinks Bucky Irving, Kenneth Gainwell Have Similar Skill Sets
Emeka Egbuka

to Settle into "Z" Role in Year 2
Trey Benson

Droppable in Some Dynasty Leagues?
Cameron Ward

Looking to Make a Year 2 Leap
Omar Cooper Jr.

to Require Some Patience in Dynasty Leagues?
Jordyn Tyson

Is Jordyn Tyson the Best Rookie Receiver in Dynasty Leagues?
Nico Collins

Still in the WR1 Tier for Dynasty Fantasy Football
Luka Dončić

Luka Doncic Admits He Wasn't Close to Returning Before Season Ended
Colston Loveland

Is Colston Loveland a Top-25 Dynasty Asset?
CFB

Isaac Brown Has All-American Upside in 2026
LeBron James

Uncertain About Future After Season-Ending Loss
Zay Flowers

Is Zay Flowers Still Undervalued Coming Off a Career Season?
Ajay Mitchell

Continues to Excel for Thunder
CFB

Nyck Harbor Heading into Breakout Year?
LeQuint Allen Jr.

a Steady Dynasty Riser During Quiet Jaguars Offseason
Shai Gilgeous-Alexander

Posts 35 Points in Series Clincher
CFB

Notre Dame, USC in Discussions to Resume Rivalry Series
Cade Cunningham

Struggles in Game 4 Loss
CFB

Jaron-Keawe Sagapolutele Has Eyes on ACC Title
James Harden

Records 40th Postseason Double-Double
CFB

Ahmad Hardy's Gunshot Wound Not Viewed as Career-Threatening
Donovan Mitchell

Ties NBA Playoff Record With 39 Second-Half Points
Tommy Fleetwood

on Upward Trend Ahead of PGA Championship
Bryson DeChambeau

a High-Upside Play With Risk at PGA Championship
Draymond Green

Set to Stay With Warriors
Stephen Curry

Warriors Looking to Extend Stephen Curry in Offseason
Giannis Antetokounmpo

Bucks Listening to Offers for Giannis Antetokounmpo
OG Anunoby

Expected to Be Ready for Game 1 of East Finals
De'Aaron Fox

Listed as Questionable for Game 5
A.J. Ewing

Mets to Call Up Top Prospect A.J. Ewing
Kevin Huerter

to Remain Sidelined in Game 4
Caris LeVert

is Cleared for Game 4 on Monday
Mookie Betts

is Officially Back on Monday
Nathan Eovaldi

Scratched From Monday's Start With Side Tightness
Mark Jankowski

Signs Two-Year Extension With Hurricanes
Joel Kiviranta

Cleared to Play Monday
Josh Manson

Available for Game 4 Monday
Mackenzie Blackwood

Expected to Start Monday
Jonas Brodin

Won't Play Monday
Joel Eriksson Ek

Remains Out Monday
Henry Bolte

Athletics to Promote Top Outfield Prospect Henry Bolte to Major Leagues
Khamzat Chimaev

Suffers his First Loss
Sean Strickland

Recaptures Middleweight Title
Tatsuro Taira

Suffers Fifth-Round TKO Loss
Joshua Van

Defends Flyweight Title
MMA

Waldo Cortes-Acosta Drops Decision
Alexander Volkov

Wins Back-To-Back Fights
Shane Van Gisbergen

Dominates Watkins Glen for First Win of 2026
Michael McDowell

Finishes Second for Best Run of the Year At Watkins Glen
Ty Gibbs

Scores New Career-Best Finish of Third at Watkins Glen
Tyler Reddick

Continues His Strong Season With Fifth-Place Run at Watkins Glen
Austin Dillon

Earns his First Top-10 Finish of 2026 at Watkins Glen
Mookie Betts

Dodgers Expect Mookie Betts to Return on Monday
CFB

Ahmad Hardy Sustains Gunshot Wound, in Stable Condition
Rasmus Dahlin

Records Two Points in Game 3 Loss
Tage Thompson

Comes Alive in Game 3 Against Canadiens
Cole Caufield

Ends Dry Spell Sunday
Alex Newhook

Nets Two More Goals in Sunday's Victory
Mitchell Marner

Notches Three Assists in Losing Effort
Connor Zilisch

Will Start Fifth in his First Watkins Glen Cup Series Race
Tyler Reddick

Is A Top DFS Option for Watkins Glen Lineups
Christopher Bell

Is Likely to Bounce Back This Week at Watkins Glen
Carlos Rodón

Carlos Rodon Activated for Season Debut on Sunday
William Byron

Is William Byron Playable in DFS Lineups at Watkins Glen?
Kyle Larson

May have A Positive Day at Watkins Glen
Chase Briscoe

May Compete for A Top-10 Finish at Watkins Glen
NASCAR

A.J. Allmendinger May have Another Solid Outing at Watkins Glen
Ty Gibbs

Should Fantasy Managers Roster Ty Gibbs at Watkins Glen?
Ross Chastain

Is Ross Chastain Worth Rostering for Watkins Glen Lineups?
Austin Cindric

Could Austin Cindric be A Sneaky Tournament Play for Watkins Glen?
Shane Van Gisbergen

Shane van Gisbergen the Heavy Favorite at Watkins Glen
Chase Elliott

Is Chase Elliott a No-Brainer DFS Pick at Watkins Glen?
Chris Buescher

Qualifies 14th at Watkins Glen
Ryan Blaney

Has Upside at Watkins Glen After Signing Contract Extension
Michael McDowell

Still Searching for First Top-Five Finish at Watkins Glen
Carson Hocevar

Is Carson Hocevar Too Aggressive for Road-Course Racing?
Luis Castillo

Mariners Intend to Piggyback Luis Castillo, Bryce Miller
Logan Webb

Placed on 15-Day Injured List With Knee Bursitis
Bryce Miller

is Set to Return on Wednesday
Jeff Hoffman

Could Return to Closer Role
Taj Bradley

Hits the Injured List With Pectoral Inflammation
Kyle Bradish

has Nice Bounce-Back Performance With 10 K's
Casey Mize

Throws Bullpen on Friday, Return Not Imminent
Ronald Acuña Jr.

Ronald Acuna Jr. Optimistic About Returning Next Wednesday
Tyler Glasnow

Dodgers Put Tyler Glasnow on Injured List With Back Spasms
Blake Snell

to Make Season Debut for Dodgers on Saturday
Cole Ragans

Royals Place Cole Ragans on Injured List With Elbow Impingement
Sean Strickland

An Underdog At UFC 328
Khamzat Chimaev

Set For UFC 328 Main Event
Tatsuro Taira

Can Become The New Flyweight Champion
Joshua Van

Set For His First Title Defense
Alexander Volkov

Looks To Win Back-To-Back Fights
MMA

Waldo Cortes-Acosta Looks To Extend His Win Streak
Nick Lodolo

Officially Activated, Making Season Debut on Friday
CFB

Walker Lyons Could be Go-To Target for Bear Bachmeier
CFB

Ty Benefield a Potential Game-Changer for LSU Defense
CFB

Hayden Lowe Set for Significant Role Following Miami's NFL Departures
CFB

Taylor Wein in Position for Big Season on Oklahoma's Defensive Line
CFB

Rasheem Biles an Instant Impact Player for Texas
CFB

Sam Leavitt Expected to Be Full-Go for Fall Camp
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF