PrizePicks NFL DFS Props Picks - Sunday Main Slate (Week 10)

Kipp's NFL DFS prop picks on PrizePicks for fantasy football Week 10 (2022) - Sunday's main slate. Use his top NFL prop picks to win money on PrizePicks.

Hello everybody and welcome! The 2022 NFL season is well underway and that means our friends over at PrizePicks have a TON of great DFS plays we can look to take advantage of. PrizePicks is a great DFS site where you can choose to select plays in terms of fantasy points or single stats. The goal is to build a 2-player, 3-player, 4-player, or 5-player entry and then select whether or not you want to play for the power play or the flex play. On the power play, you will need to be correct on each of your selections to win, and on the flex play, you will have a little more wiggle room for a chance to win some money back.

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NFL DFS Picks for Week 10

Before diving into some solid fantasy score totals this week, we must first cover the PrizePicks scoring format. The format is PPR, which stands for "point per reception," meaning every reception is worth one point. Rushing and receiving touchdowns are worth six points and passing touchdowns are worth four points. Each rushing or receiving yard is worth .1, meaning every 10 yards of either is worth one point. Quarterback passing yards are worth .04, which means every 25 passing yards are worth one point. If you ever have questions, you can always click the "scoring chart" option above the player selections for each contest. Now let's get to some solid fantasy score props for this week.

Amari Cooper more than 61.5 receiving yards  - Cooper has eclipsed this total in three of his previous five games while garnering nearly nine targets per game over that span. The Browns will enter this game as four-point underdogs to the Dolphins, which should lead to some additional passing. This should be a good thing for Cooper against a defense that has allowed an average of 135 receiving yards to the position over the previous four weeks.

Christian Kirk more than 62.5 receiving yards - Kirk and the Jaguars will enter this game as nearly 10-point underdogs, which is a big reason I think Kirk gets over this total as the Jags will be forced to pass later in the game to keep up with the Chiefs. Kirk has gone over this total in two of his previous three games. He has also earned at least seven targets in each of his previous three games. Meanwhile, the Chiefs have allowed an average of nearly 153 receiving yards per game to wideouts over their previous three games.

Russell Wilson more than 226.5 passing yards - This pick makes me a little ill as no one wants to play Wilson these days, but the matchup here is superb, especially considering Mahomes just lit Tennessee up for over 400 passing yards. Wilson has eclipsed this total in three of his previous five games and Tennessee has allowed an average of nearly 296 passing yards per game to quarterbacks on the season.

Derrick Henry more than 97.5 rushing yards - We are going to stay in the same game with this last pick as Henry has eclipsed this total in five straight games while averaging nearly 136 rushing yards per game over that span. Tennessee will enter as three-point favorites, so some additional rushing attempts could be expected down the stretch. Denver has also allowed an average of nearly 103 rushing yards per game to backs on the season.

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