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Is Brock Purdy out for the season? When is Brock Purdy coming back? The latest Brock Purdy injury update and fantasy football outlook heading into Week 3 of 2025.
San Francisco 40ers quarterback Brock Purdy joins the long list of high-end players on the roster who are sidelined. Currently, tight George Kittle (hamstring) and top wide receiver Brandon Aiyuk (knee) are both on the injured list and are in danger of missing a significant part of the season.
Purdy was unable to play in Week 2 due to turf toe and appears to be in danger of missing Week 3.
Will Purdy play again this season? Should fantasy managers stash him on their bench? Let's dive in!
Be sure to check all of our fantasy football rankings for 2025:- 2025 fantasy football rankings
- Running back (RB) fantasy football rankings
- Wide receiver (WR) fantasy football rankings
- Tight end (TE) fantasy football rankings
- Quarterback (QB) fantasy football rankings
- FLEX fantasy football rankings
- Defense (D/ST) fantasy football rankings
- Kicker (K) fantasy football rankings
- Dynasty fantasy football rankings
Is Brock Purdy Out for the 2025 Season?
Leading up to Week 2, Prudy was dealing with a "turf toe variant," according to Ian Rapoport of the NFL Network. Purdy reportedly suffered this injury during their Week 1 victory over the Seattle Seahawks. In this contest, Purdy also suffered a shoulder injury, but this injury does not seem as serious as the form of turf toe.
From @GMFB: #Commanders QB Jayden Daniels (wrist) is off the injury report, while #49ers QB Brock Purdy is out 2-5 weeks with a turf toe variant, sources say. pic.twitter.com/xQPT3Jm3cS
— Ian Rapoport (@RapSheet) September 11, 2025
He was unable to progress, which paved the way for Mac Jones to get the starting nod in Week 2, and he was able to lead the 49ers to victory.
Shortly before this contest, Adam Schefter of ESPN reported that the team is not "optimistic" that Purdy would be able to turn the corner in time to suit up in Week 3 when the 49ers face the Arizona Cardinals. A source said that while Purdy has gotten better, "next week will be tight."
49ers are not optimistic Brock Purdy will return from his toe injury for a Week 3 matchup vs. Arizona, but it’s not out of the question and he has improved. “We’ll see for next week,” one source said about Purdy. “Next week will be tight, but he progressed a lot this week.” pic.twitter.com/jWqFuKCia5
— Adam Schefter (@AdamSchefter) September 14, 2025
While Purdy is trending in the wrong direction for the short-term, fantasy managers should not be overly concerned with his availability for the majority of the campaign. Seeing that Purdy still has a path to suit up in Week 3, even if it is unlikely, suggests he could be in a good position to return in Week 4.
Fantasy managers should continue to stash him on all their rosters as he appears to be trending toward a return in Week 4.
Brock Purdy 2025 Fantasy Football Outlook
Even if Purdy is unable to play in Week 3, he still carries QB1 upside for the remainder of the campaign. In Week 1, Purdy enjoyed a strong start to the season, going 26-for-35 with 277 yards and a 2:2 TD:INT. In this contest, Purdy added 17 yards on the ground. In addition, during this game, Purdy lost his top target, Kittle, in the opening half due to injury, and was without Aiyuk, but he was still able to produce QB1 numbers.
With both Kittle and Aiyuk slated to return later this season, the entire offense should see a substantial boost in the second half.
In 2023 and 2024, Purdy produced as a QB1 in all formats, averaging 22.8 and 22.4 PPR points per game in each season. In 2023, Purdy was surrounded by numerous offensive weapons and totaled a career best 4,280 yards with 31 passing scores, 144 rushing yards, and two rushing scores.
However, in 2024, playing without Deebo Samuel Sr., Christian McCaffrey, and Aiyuk for the majority of the campaign, Purdy continued to produce QB1 numbers, throwing for 3,864 yards with 20 touchdowns. He relied on his legs more often as he ran for 323 yards and five scores, both career highs.
Brock Purdy lays out for the @49ers TD!
📺: #SEAvsSF on FOX
📱: https://t.co/waVpO8ZBqG pic.twitter.com/7OlI7fdb3J— NFL (@NFL) November 17, 2024
Seeing Purdy rely more on his legs last season could set him up for a dominant second half this season, especially if he can overcome this injury and the offense welcomes back both Kittle and Aiyuk at full strength.
With Ricky Pearsall and Jauan Jennings proving to be stable options in the passing attack, this offense is in a great position to improve as the season progresses, once Purdy, Kittle, and Aiyuk are at full strength.
Purdy will be a solid top-10 option in all formats when he is cleared to return.
Who Should I Start Tool
Not sure who to start? Check out the Who Should I Start tool:
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Who Should I Start? Who Should I Sit? Some common Week 3 fantasy football lineup decisions are regarding players like Daniel Jones, Justin Fields, Caleb Williams, Bo Nix, Jordan Love. But not to worry, we are here to help make these decisions and build winning lineups in Week 2. Set your optimal fantasy football lineups for Week 3 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
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Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player name. In the second box, search for the second player name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.
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Popular Week 3 Searches. Curious to see some tough lineup decisions for Week 2 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 3 Searches - Start/Sit Player Comparisons
Below are some popular Week 3 searches and comparisons from our 'Who To Start' tool for Daniel Jones, Justin Fields, Caleb Williams, Bo Nix, Jordan Love compared to others:
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