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Fantasy football rankings - updated defense (DST) Week 6 rankings for 2025. Read the top-accuracy fantasy football DEF rankings for NFL team defenses.
Through the first five weeks of the fantasy football season, we have seen several spike weeks carry fantasy managers to wins. It's important to find a high-upside D/ST each week, so use updated Week 6 fantasy football defense (DST) rankings for 2025 to pinpoint the best team defense for your lineups. In the rankings below, you will see where the Green Bay Packers, Los Angeles Rams, Seattle Seahawks, New England Patriots, Las Vegas Raiders, and Buffalo Bills defenses stand, among all other D/STs.
Our defense fantasy football rankings for Week 6 are put together by Nick Mariano. Below the rankings, you will also find key fantasy football outlooks from our RotoBaller staff, as well as the "Who to Start?" tool. Also, be sure to check our fantasy football news for this week. There are always key injuries and developments to keep track of, so check back throughout the week for updates.
Be sure to bookmark our fantasy football rankings portal and check back regularly for updates. Most importantly, our free mobile app is a must-have - download it and configure your push notifications. We deliver all the top NFL news, injuries, and fantasy analysis 24x7 with our free push notification alerts... all for free!
Be sure to check all of our fantasy football rankings:- Overall fantasy football rankings
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Week 6 Defense (DST) Rankings for Fantasy Football
Bookmark our PPR rankings, Half-PPR rankings, and standard (non-PPR) rankings
| D/ST Tier | D/ST Rank | D/ST Name | Position |
| 1 | 1 | Green Bay Packers | DST |
| 1 | 2 | Philadelphia Eagles | DST |
| 1 | 3 | Pittsburgh Steelers | DST |
| 1 | 4 | Los Angeles Rams | DST |
| 2 | 5 | Denver Broncos | DST |
| 2 | 6 | Seattle Seahawks | DST |
| 3 | 7 | Indianapolis Colts | DST |
| 3 | 8 | Cleveland Browns | DST |
| 3 | 9 | Buffalo Bills | DST |
| 3 | 10 | Los Angeles Chargers | DST |
| 4 | 11 | New England Patriots | DST |
| 4 | 12 | Arizona Cardinals | DST |
| 4 | 13 | Las Vegas Raiders | DST |
| 4 | 14 | Dallas Cowboys | DST |
| 5 | 15 | Tennessee Titans | DST |
| 5 | 16 | Detroit Lions | DST |
| 5 | 17 | Jacksonville Jaguars | DST |
| 5 | 18 | Washington Commanders | DST |
| 5 | 19 | Tampa Bay Buccaneers | DST |
| 5 | 20 | Miami Dolphins | DST |
| 6 | 21 | Kansas City Chiefs | DST |
| 6 | 22 | San Francisco 49ers | DST |
| 6 | 23 | New Orleans Saints | DST |
| 6 | 24 | Chicago Bears | DST |
| 6 | 25 | New York Jets | DST |
| 7 | 26 | Carolina Panthers | DST |
| 7 | 27 | Atlanta Falcons | DST |
| 7 | 28 | New York Giants | DST |
| 7 | 29 | Baltimore Ravens | DST |
| 8 | 30 | Cincinnati Bengals | DST |
Week 6 Defense (DST) Rankings Outlooks
Pittsburgh Steelers D/ST
The Pittsburgh Steelers, fresh off their Week 5 bye, are getting healthier on defense ahead of a divisional clash with the Cleveland Browns. Although defensive back Jalen Ramsey (hamstring) is questionable to suit up, cornerback Joey Porter Jr. (hamstring) and linebacker Alex Highsmith (ankle) are set to return after missing multiple games.
Pittsburgh's defense wreaked havoc in Weeks 3 and 4, forcing seven turnovers and recording 11 sacks, and now returns home to face rookie quarterback Dillon Gabriel in his second NFL start. While Ramsey's availability could slightly impact the unit's ceiling, there are few safer fantasy options than the Steelers DST this week in what projects to be a low-scoring affair.
Green Bay Packers D/ST
The Packers' defense and special teams unit are coming off a disappointing performance in Week 4, where they gave up 40 points to the Dallas Cowboys. That resulted in a 40-40 tie, and the team had to sit on that loss for a week as the Packers had their Week 5 bye to get right. Luckily, they host the Cincinnati Bengals in Week 6, who are on their third quarterback this season.
It's a familiar signal-caller, as Joe Flacco takes the reins of the Bengals' offense to face the Packers for the second time in three weeks. The Packers are a good bet to get back to basics and dominate a weaker Cincinnati offensive line. At home and well-rested, the Packers are one of the best D/ST plays of the Week 6 slate and should be started universally in fantasy football this week.
Las Vegas Raiders D/ST
The Las Vegas Raiders' defense has endured a rough start to the season, logging negative fantasy outputs twice and only delivering in their Week 1 matchup against the Patriots. However, Week 6 presents a prime opportunity for a rebound as they face a struggling Tennessee Titans offense. The Titans have surrendered the second-most fantasy points to opposing defenses this season and continue to rank near the bottom in nearly every major offensive category.
With Maxx Crosby anchoring the pass rush, the Raiders have a strong chance to generate turnovers and sacks against a mistake-prone Titans squad. Fantasy managers seeking a streaming option should look no further--Las Vegas profiles as a sneaky top-10 defensive play this week with legitimate upside in a favorable matchup.
Los Angeles Rams D/ST
The Los Angeles Rams defense should be started in most fantasy leagues ahead of Week 6 against the Baltimore Ravens. While Baltimore is typically a very strong offense, the unit has struggled lately, largely due to the absence of Lamar Jackson (hamstring).
Jackson has been ruled out for Sunday, which means that Cooper Rush will be tasked with quarterbacking the Ravens against a strong Rams defense. Rush took one sack and threw three interceptions last week, providing a huge boost to the Texans D/ST in fantasy football. The Rams D/ST should experience a similar boost this week. RotoBaller has the Rams ranked #4 among all D/ST units for Week 6.
Who Should I Start Tool
Not sure who to start? Check out the Who Should I Start tool:
Compare up to four players and we'll tell you who to start...
Who Should I Start? Who Should I Sit? Some common Week 6 fantasy football lineup decisions are regarding defense options like Green Bay Packers, Los Angeles Rams, Seattle Seahawks, New England Patriots, Las Vegas Raiders, and Buffalo Bills. But not to worry, we are here to help make these decisions and build winning lineups in Week 6.
Week 6 Player Decisions. Set your optimal fantasy football lineups for Week 6 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.
Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player's name. In the second box, search for the second player's name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.
Improvements For Who Should I Start? You may have noticed, we've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, enhanced search results with data to compare, and a slick new interface. We hope you enjoy!
How It Works. Each week, our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.
Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do is to select the scoring format. There are three small radio buttons (small circles), so click on the scoring format you prefer. The results may vary based on the scoring format you select.
Popular Week 6 Searches. Curious to see some tough lineup decisions for Week 6 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.
Popular Week 6 Searches - Start/Sit Player Comparisons
Below are some popular Week 6 searches and comparisons from our 'Who To Start' tool:
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