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FanDuel Daily Fantasy Football Lineup Picks (Week 6): NFL DFS Advice

Justin Bales' week six FanDuel lineup picks. Daily fantasy football sleepers, value picks and lineups advice for FanDuel DFS games and tournaments.

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 6 of the NFL season. In this article, I, Justin Bales, will be taking you, the reader, through the best FanDuel DFS plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. Good luck with your FanDuel DFS lineups!

Editor's Note: If you like FanDuel, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

Editor's Note: Find sleeper picks, undervalued ADPs, and draft targets to help you dominate your fantasy football drafts. Try our free who to draft tool for personalized recommendations.

 

FanDuel Quarterback - Week 6 DFS Picks

Drew Brees (vs CAR, $8,500)

Drew Brees could go a little under owned this season, as people seem to be focusing more on the Panthers offense than the Saints offense. Brees is always an elite option at home and the Panthers have been an average pass defense this season. Brees has scored 26.94 and 31.42 fantasy points in two home starts, while this game has a 53 point total. The Saints are small underdogs, which means they will be throwing the entire game, and Brees should have no problems hitting value this week.

 

FanDuel Running Backs - Week 6 DFS Picks

Le'Veon Bell (at MIA, $9,300)

Le'Veon Bell is one of the most expensive players on the slate, and for good reason. He's essentially a wide receiver playing running back at this point in the season. He's consistent lining up in the slot, and he has 17 targets through two games. He also has 38 carries in those games, and is truly a workhorse player. He gets a good matchup against the Dolphins where the Steelers are -7 point favorites. They should get an early lead and rely heavily on Le'Veon Bell to run the clock out in the second half. He's an elite option this weekend.

Carlos Hyde (at BUF, $7,300)

Carlos Hyde is a volume runner, and the 49ers have no problem giving him the volume he needs. He's also an elite red zone option, as he has six touchdowns in five weeks this season. He gets somewhat of a tough matchup against the Bills, but they aren't an elite defense by any means. The 49ers are big underdogs, but they are every week, and they have no problem giving Hyde the ball when they are losing. He's also coming off a six reception game, which adds even more value to him as a player. He's a high upside tournament option this week.

 

FanDuel Wide Receivers - Week 6 DFS Picks

Mike Wallace (at NYG, $6,400)

Steve Smith Sr. is dealing with an injury and he likely will not play this week. That will bump Mike Wallace to the top receiver, as can be seen last week when Smith got hurt and Wallace ended the game with 11 targets. The Ravens also fired their offensive coordinator, and replaced him with Marty Mornhinweg. Mornhinweg loves running the ball, but his offenses also always rank in the top of the league in big plays, which is where Wallace is at his best. He'll have a high floor because of his volume, but he also comes with an elite ceiling. He's a great option in all leagues against the Giants secondary.

Cameron Meredith (vs JAC, $5,400)

Meredith will likely be chalk this week, and it would be wise to use him. He's coming off a game in which he had nine receptions for 130 yards and one touchdown on 12 targets. Brian Hoyer recently stated that if teams are going to take away Alshon Jeffery, the Bears will have to beat them in other ways, which suggests Meredith will continue to see the large amount of targets. He's a big player with touchdown potential, and he's too cheap this week. Cash teams should be started with him.

 

FanDuel Tight End - Week 6 DFS Picks

Jimmy Graham (vs ATL, $6,900)

Jimmy Graham struggled early in the season, but he has 12 receptions for 213 yards and one touchdown on 17 targets over his last two games. There was a report that Graham and Russell Wilson have been working out together after practice to establish a rhythm, and it has worked out recently. He gets a good matchup against the Falcons, and the Seahawks should be able to score plenty of points this week. Graham comes with great upside, but he's significantly cheaper than the elite tight ends on the slate. He can safely be used in all leagues.

 

FanDuel Defense - Week 6 DFS Picks

Detroit Lions D/ST (vs LA, $4,500)

The Lions defense and special teams has struggled quite a bit this season, but this is an elite matchup. The Rams have the worst offense in the NFL, and they have struggled to score this season. The Lions haven't looked great, but they are -2.5 favorites in a game set at only 43.5 points. Unfortunately, the Vikings are on bye this week, so we'll have to find a someone else to use. The Lions will allow you to spend more money at other positions, which is never a bad idea when there is a low game total.




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REAL-TIME FANTASY NEWS

Will Smith

Out Week-to-Week
Jaccob Slavin

Placed on Injured Reserve, Out Week-to-Week
Seth Jarvis

Considered Week-to-Week
Darren Raddysh

Totals Three Points in Monday's Win
Mason Marchment

Scores Twice Monday
Vince Dunn

Injured in Monday's Win
Grayson Allen

Likely to Miss Third Straight Game
Rui Hachimura

Misses Second Consecutive Game Tuesday
Jaden McDaniels

Iffy for Tuesday
Jakob Poeltl

Out Against Heat
Khris Middleton

Available Versus Hornets
Corey Kispert

Returns to Wizards Lineup Tuesday
Bilal Coulibaly

Questionable Tuesday
Zach LaVine

Remains Unavailable Tuesday
Tristan da Silva

Ruled Out for Monday
Jalen Suggs

Ruled Out for Monday
Quentin Grimes

Uncertain to Suit Up Against Nets
Aaron Wiggins

Ruled Out for Monday
Dominick Barlow

Might Miss Tuesday's Meeting with Brooklyn
Deandre Ayton

Available Against Suns
Jalen Duren

Available for Monday
Alexandre Sarr

Off the Injury Report for Tuesday
Austin Reaves

May Return on Tuesday
Tyler Herro

Not Ready to Return Tuesday
Ron Holland II

Ruled Out for Monday
OG Anunoby

Ruled Out for Tuesday
Jerami Grant

Ruled Out for Monday
Rashee Rice

Still in Concussion Protocol, Estimated as Non-Participant on Monday
J.J. McCarthy

Listed as DNP on Monday Ahead of Week 17
Ilya Sorokin

to Miss Tuesday's Game
DK Metcalf

Suspended for Two Games Following Confrontation with Fan
Christian Dvorak

Returns to Flyers Lineup
Elias Pettersson

Still Out Monday
Brandon Montour

to Miss Four Weeks After Hand Surgery
Miles Wood

Available Against Kings
Zach Werenski

Ruled Out Monday
Leo Carlsson

Won't Play Monday
CFB

Byrum Brown Entering Transfer Portal
CFB

Bobby Petrino Joining Bill Belichick as North Carolina's Offensive Coordinator
TreVeyon Henderson

Exits Week 16 Victory with Head Injury
Mikhail Sergachev

Sets Up Two Goals
Fabian Zetterlund

Extends Scoring Streak With Three-Point Effort
Cale Makar

Has Three-Point Performance Against Wild
Tomas Hertl

Notches Three Points Sunday
Connor McDavid

Continues Scoring Tear Against Vegas
Sidney Crosby

Becomes Pittsburgh's All-Time Leading Scorer
Tristan Jarry

to Miss Couple of Weeks
Lamar Jackson

Questionable to Return in Week 16 with Back Injury
Willson Contreras

Shipped to the Red Sox
Patrick Kane

to Miss Fifth Consecutive Game
Quinshon Judkins

Done for the Season with Broken Leg
Nick Chubb

Officially Active Against Raiders in Week 16
Gardner Minshew

Won't Return in Week 16
Woody Marks

Officially Inactive for Week 16
Quinshon Judkins

Carted Off in Week 16, Ruled Out with Apparent Leg Injury
Tua Tagovailoa

Dolphins Hope to Trade Tua Tagovailoa in the Offseason
Woody Marks

Not Expected to Play in Week 16
Washington Commanders

Commanders to Retain Dan Quinn, Fire Joe Whitt?
New York Giants

Marcus Freeman is a Top Candidate in Giants' Head Coaching Search
Cincinnati Bengals

Zac Taylor Expected to Return as Bengals' Head Coach in 2026
Las Vegas Raiders

Pete Carroll's Future with Las Vegas Raiders in Doubt
Tee Higgins

Active for Week 16 Against Dolphins
Woody Marks

Plans to Play Against Raiders in Week 16
Tee Higgins

Likely to Play at Miami on Sunday
Drake London

Expected to Return in Week 16
Marvin Harrison Jr.

Expected to Play, Will Ease Back In
Brandon Lowe

Pirates Acquire Brandon Lowe in Three-Team Trade
Shane Baz

Orioles Acquire Shane Baz From the Rays
CFB

Darian Mensah Returning to Duke Next Season
CFB

Josh Hoover Linked to Indiana in Transfer Portal
CFB

Arch Manning Agrees to Reduced Compensation for 2026 Season
Michael King

Padres Bring Michael King Back on Three-Year Deal
Logan Webb

Will Pitch for Team USA in World Baseball Classic
Tarik Skubal

Joins Team USA for World Baseball Classic
CFB

Will Muschamp Becoming Next Texas Defensive Coordinator
CFB

Beau Pribula Set to Enter Transfer Portal
Bo Bichette

Willing to Make the Move to Second Base
CFB

Jeremiyah Love Officially Heading to NFL Draft
CFB

Jake Merklinger Leaving Tennessee for Transfer Portal

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