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FanDuel Daily Fantasy Football Lineup Picks (Week 6): NFL DFS Advice

Justin Bales' week six FanDuel lineup picks. Daily fantasy football sleepers, value picks and lineups advice for FanDuel DFS games and tournaments.

Welcome to RotoBaller's daily fantasy football FanDuel lineup picks for Week 6 of the NFL season. In this article, I, Justin Bales, will be taking you, the reader, through the best FanDuel DFS plays of the week for this upcoming Sunday.

These FanDuel lineup recommendations are based on matchups, recent performances, overall upside/talent levels, and other factors such as Vegas odds, home field advantage, and more. Good luck with your FanDuel DFS lineups!

Editor's Note: If you like FanDuel, be sure to also check out FantasyAces. New users that sign up on Fantasy Aces and make a $20 deposit will receive RotoBaller's full season NFL Premium Pass for free (including Premium DFS), normally a $59.99 value. Expert DFS research, sample lineups, matchup ratings and lots more!

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FanDuel Quarterback - Week 6 DFS Picks

Drew Brees (vs CAR, $8,500)

Drew Brees could go a little under owned this season, as people seem to be focusing more on the Panthers offense than the Saints offense. Brees is always an elite option at home and the Panthers have been an average pass defense this season. Brees has scored 26.94 and 31.42 fantasy points in two home starts, while this game has a 53 point total. The Saints are small underdogs, which means they will be throwing the entire game, and Brees should have no problems hitting value this week.

 

FanDuel Running Backs - Week 6 DFS Picks

Le'Veon Bell (at MIA, $9,300)

Le'Veon Bell is one of the most expensive players on the slate, and for good reason. He's essentially a wide receiver playing running back at this point in the season. He's consistent lining up in the slot, and he has 17 targets through two games. He also has 38 carries in those games, and is truly a workhorse player. He gets a good matchup against the Dolphins where the Steelers are -7 point favorites. They should get an early lead and rely heavily on Le'Veon Bell to run the clock out in the second half. He's an elite option this weekend.

Carlos Hyde (at BUF, $7,300)

Carlos Hyde is a volume runner, and the 49ers have no problem giving him the volume he needs. He's also an elite red zone option, as he has six touchdowns in five weeks this season. He gets somewhat of a tough matchup against the Bills, but they aren't an elite defense by any means. The 49ers are big underdogs, but they are every week, and they have no problem giving Hyde the ball when they are losing. He's also coming off a six reception game, which adds even more value to him as a player. He's a high upside tournament option this week.

 

FanDuel Wide Receivers - Week 6 DFS Picks

Mike Wallace (at NYG, $6,400)

Steve Smith Sr. is dealing with an injury and he likely will not play this week. That will bump Mike Wallace to the top receiver, as can be seen last week when Smith got hurt and Wallace ended the game with 11 targets. The Ravens also fired their offensive coordinator, and replaced him with Marty Mornhinweg. Mornhinweg loves running the ball, but his offenses also always rank in the top of the league in big plays, which is where Wallace is at his best. He'll have a high floor because of his volume, but he also comes with an elite ceiling. He's a great option in all leagues against the Giants secondary.

Cameron Meredith (vs JAC, $5,400)

Meredith will likely be chalk this week, and it would be wise to use him. He's coming off a game in which he had nine receptions for 130 yards and one touchdown on 12 targets. Brian Hoyer recently stated that if teams are going to take away Alshon Jeffery, the Bears will have to beat them in other ways, which suggests Meredith will continue to see the large amount of targets. He's a big player with touchdown potential, and he's too cheap this week. Cash teams should be started with him.

 

FanDuel Tight End - Week 6 DFS Picks

Jimmy Graham (vs ATL, $6,900)

Jimmy Graham struggled early in the season, but he has 12 receptions for 213 yards and one touchdown on 17 targets over his last two games. There was a report that Graham and Russell Wilson have been working out together after practice to establish a rhythm, and it has worked out recently. He gets a good matchup against the Falcons, and the Seahawks should be able to score plenty of points this week. Graham comes with great upside, but he's significantly cheaper than the elite tight ends on the slate. He can safely be used in all leagues.

 

FanDuel Defense - Week 6 DFS Picks

Detroit Lions D/ST (vs LA, $4,500)

The Lions defense and special teams has struggled quite a bit this season, but this is an elite matchup. The Rams have the worst offense in the NFL, and they have struggled to score this season. The Lions haven't looked great, but they are -2.5 favorites in a game set at only 43.5 points. Unfortunately, the Vikings are on bye this week, so we'll have to find a someone else to use. The Lions will allow you to spend more money at other positions, which is never a bad idea when there is a low game total.




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REAL-TIME FANTASY NEWS

Kyle Anderson

Likely Out Monday
Cedric Coward

Remains Out Vs. Kings
Kawhi Leonard

Cleared to Play Sunday
Jalen Suggs

Misses Second Straight Game
Shohei Ohtani

Throws Live Batting Practice on Sunday
Patrick Williams

Available Against Knicks
Rhys Hoskins

Guardians Sign Rhys Hoskins to Minor-League Deal
Deni Avdija

Good to Go Against Suns
Tre Jones

Josh Giddey, Tre Jones Facing Minute Caps Sunday
Jack Brannigan

Exits After Getting Hit in the Face
Nick Richards

Active Sunday Against Knicks
Dairon Blanco

Being Evaluated for Head Injury
Grayson Allen

Jalen Green Active, Grayson Allen Sidelined Sunday
Aidan Miller

is Dealing with Back Soreness
Keyonte George

Faces Game-Time Decision Monday
Naz Reid

Out, Joan Beringer to Start Vs. 76ers
Lauri Markkanen

Probable to Return Monday
Jusuf Nurkić

Jusuf Nurkic Out Monday Against Rockets
Jamal Murray

Good to Go on Sunday
Brandon Lowe

Could Be Poised for Banner Year in Pittsburgh
TJ Friedl

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Bryson Stott

Remains a High-Floor, Low-Ceiling Second Base Option
Anfernee Simons

Won't Face the Knicks
Mitchell Robinson

Sitting on Sunday
Jeremy Peña

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Myles Turner

Back on Sunday
Ronald Acuña Jr.

Ronald Acuna Jr. Will Bat Leadoff in 2026
Kristaps Porzingis

Ruled Out on Sunday
Joey Logano

Will Be Popular DFS Pick at EchoPark Speedway
Tyler Reddick

on Pole After Qualifying Rained Out at EchoPark Speedway
Chase Elliott

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Ryan Blaney

Is Ryan Blaney Worth Rostering for DFS at EchoPark Speedway?
Christopher Morel

is Getting Comfortable at First Base
Taylor Walls

is Making Spring Debut on Sunday
Lenyn Sosa

Likely Headed Towards Bench Role
Joe Ryan

is Dealing with Back Inflammation
William Byron

Is William Byron Worth Rostering for DFS at EchoPark Speedway?
Jordan Westburg

has Uncertain Timetable to Return
Rondale Moore

Passes Away
Denny Hamlin

Is Worth Consideration for EchoPark Speedway DFS Lineups
Brad Keselowski

Is A Tournament Option for DFS At EchoPark Speedway
NASCAR

Is Bubba Wallace Rosterable In DFS At EchoPark Speedway?
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Alex Bowman

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Anfernee Simons

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Kristaps Porzingis

On Track To Play Sunday
Shaedon Sharpe

Remains Unavailable Sunday
Tyler Samaniego

Dealing with Back Tightness
Cam Schlittler

Throws Bullpen Session on Saturday
Cody Freeman

to Miss Significant Time with Back Fracture
Javonte Williams

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Logan Gilbert

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Jonathon Long

Exits With Left-Elbow Sprain
Joel Armia

Wraps Up Olympics With Three-Point Performance
Daniil Tarasov

Available for Panthers
Evan Rodrigues

Set to Return Next Week
Aaron Ekblad

Expected to Play Thursday
Pavel Zacha

Cleared for Action
VAN

Jonathan Lekkerimaki Needs Season-Ending Shoulder Surgery
Mikko Rantanen

Misses Bronze-Medal Game With Lower-Body Injury
Joe Ryan

Scratched From Grapefruit League Start With Back Tightness
Blake Coleman

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Matt Rempe

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Josh Morrissey

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Makes History With Another Multi-Point Outing
Tage Thompson

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Travis Etienne Jr.

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Zach Charbonnet

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Curt Cignetti Agrees to New Deal With Indiana, Will Earn $13.2 Million Per Year
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Returns to Practice
Josh Morrissey

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Sidney Crosby

Won't Play Friday
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Geoff Neal

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Melquizael Costa

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Dan Ige

An Underdog At UFC Houston
Logan Cooley

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Maxwell Crozier

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Kirill Marchenko

Dealing With Lower-Body Injury
Petr Mrazek

Undergoes Season-Ending Surgery
Rashee Rice

Accused of Assault by Long-Time Girlfriend
Ben Griffin

Looking to Return to Top Form at Riviera
Keegan Bradley

Looking to Build Momentum at Riviera
J.J. Spaun

Putting a Major Concern at Riviera
Sepp Straka

May Have Tough Time at The Genesis Invitational
Shane Lowry

Trending Up Entering the Genesis Invitational
Justin Rose

Off Most Radars at The Genesis Invitational
Robert MacIntyre

a Long Hitter to Watch at Riviera Country Club
Jake Knapp

Red-Hot Heading to Riviera
Min Woo Lee

Attempts to Build Momentum After Pebble Beach
Harry Hall

an Unknown for The Genesis Invitational
Matt Fitzpatrick

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Wyndham Clark

Not Likely to Contend at Genesis Invitational
Ludvig Aberg

Might Find the Genesis Invitational More Challenging
Harris English

Carries Strong Form to Riviera
Patrick Cantlay

Eyes Another Strong Week at The Genesis Invitational
Daniel Berger

Needs Short Game to Show Up at Riviera
Sam Burns

Hopes Return to Form Continues at Riviera
Collin Morikawa

Riding Wave of Victory Into Riviera
Hideki Matsuyama

Looks to Have Repeat Success at The Genesis Invitational
Scottie Scheffler

Looks to Find Paydirt at Riviera
Xander Schauffele

Rounding into Form Before Genesis Invitational
Mike Evans

Will Return in 2026
Kenneth Walker III

Seahawks Not Expected to Use Franchise Tag on Kenneth Walker III
RANKINGS
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3B
SS
OF
SP
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