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Indianapolis Colts running back Jonathan Taylor is a superb fantasy start for his Monday night home matchup with the San Francisco 49ers. Taylor remained the Colts' workhorse in Week 15's loss to the Seahawks, notching his eighth game of the campaign with at least 80 rushing yards, handling his second-highest carry total of the season (25). It's worth noting that veteran backfield mate Ameer Abdullah has seen an increased snap share across the previous two weeks, though it shouldn't affect Taylor's position as a locked-in RB1, even against a sound 49ers' rush defense. San Fran has been stingy to opposing ground games, yielding the twelfth-fewest rushing yards per contest (106.1). That said, they've allowed RBs to rack up the second-most receptions of any squad (78). Veteran signal-caller Philip Rivers adds an extra variable to the equation, but that should mean that Indy will continue to rely on the rushing attack as they try to remain in playoff contention. Fantasy managers can fire up the 26-year-old as RotoBaller's PPR RB6 for Week 16's slate of action.--Alex Ciulla
Source: ESPN
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REAL-TIME FANTASY NEWS

Romeo Doubs

Questionable to Return Against Bears in Week 16
Jordan Love

Ruled Out with Concussion, Replaced by Malik Willis
Jalen Smith

Expected to Remain in Lineup Sunday
Ayo Dosunmu

Probable for Meeting With Hawks
Jordan Love

Evaluated for Concussion, Questionable to Return
Coby White

Iffy for Sunday
Andrew Wiggins

May Remain Out Sunday
Davion Mitchell

Questionable for Sunday
Tyler Herro

to Miss Fourth Straight Game Sunday
Trae Young

Available for Sunday's Tilt
Doug McDermott

Active on Saturday
Rui Hachimura

Misses Battle of Los Angeles
Jerami Grant

Won't Play Saturday Night, Kris Murray Joins Starting Unit
Jonathan Isaac

Tristan da Silva Out, Jonathan Isaac Returns for Magic Saturday
Jalen Suggs

Out Against Jazz
Lauri Markkanen

Misses Second Consecutive Game
Grayson Allen

Unavailable Against Warriors
Jonathan Kuminga

Misses Saturday's Action Due to Illness
Cam Spencer

Makes Third Career Start Saturday
Cam Whitmore

Jamir Watkins Out Against Grizzlies
Bilal Coulibaly

Departs Lineup Saturday
Khris Middleton

Ready to Face Grizzlies
Pat Connaughton

Tre Mann, Pat Connaughton Active Saturday
D'Andre Swift

Officially Active Against Packers on Saturday
Dontayvion Wicks

Christian Watson and Dontayvion Wicks Active for Week 16
Caris LeVert

Cleared for Action Saturday
Marcus Mariota

Questionable to Return with Hand Injury
Josh Jacobs

Active for Saturday's Game
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Ruled Out for Week 16
Mike Matheson

Returns Against Former Team Saturday
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Misses Saturday's Game
Mackie Samoskevich

Out on Saturday
Anthony Cirelli

Available Against Hurricanes
Brandon Hagel

Added to Injured Reserve
Nikita Kucherov

a Game-Time Call Saturday
J.T. Miller

Injured in Saturday's Win
Christian Watson

Should Be Able to Go Against Bears
Zach Bogosian

Unavailable Saturday
Marcus Johansson

Questionable for Saturday
Bo Horvat

to Miss Fourth Straight Game Saturday
Seth Jarvis

to Be "Out for a While"
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Rejoins Canadiens for Draft Pick
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to Remain Out Saturday
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Considered Week-to-Week
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to Miss at Least Two More Games
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Likely Won't Play in Week 17
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Misses Friday's Contest
Evan Rodrigues

Available Against Hurricanes
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Undergoes Surgery, to Be Re-Evaluated After Olympics
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Listed as Questionable for Week 16
Drake London

Expected to Play Sunday
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Questionable to Play in Week 16
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Will Start at RB in Week 16
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Will Practice on Friday, Expected to Play on Sunday
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Shelved for Remainder of 2025
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Josh Hoover Linked to Indiana in Transfer Portal
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Arch Manning Agrees to Reduced Compensation for 2026 Season
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Delivers Career-Best Performance on Thursday Night Football
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Jaguars Agree to Three-Year Extension With Jakobi Meyers
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Officially Out on Thursday Night
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Beau Pribula Set to Enter Transfer Portal
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Willing to Make the Move to Second Base
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Jeremiyah Love Officially Heading to NFL Draft
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Jake Merklinger Leaving Tennessee for Transfer Portal
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Kansas State's Jayce Brown Intends to Transfer
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Nation's Leading Passer Drew Mestemaker to Enter Transfer Portal
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Phillies Planning to Start Justin Crawford in Center Field
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Jayden Maiava Signs New Deal to Return to USC
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Aidan Mizell Won't Return to Florida, Entering Transfer Portal
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East Carolina Targeting Jordan Davis as Next Offensive Coordinator
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Michigan QB Jadyn Davis Set to Enter Transfer Portal
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Travis Williams Joining Texas A&M Defensive Staff
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Dylan Raiola Entering His Name into Transfer Portal
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Cincinnati's Brendan Sorsby Plans to Transfer When Portal Opens
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Baylor, LSU, Miami Among Potential Suitors for DJ Lagway
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Aidan Chiles Will Enter Transfer Portal
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Gets Second-Round Knockout Win
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Suffers His First Career Knockout Loss
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Quarterback DJ Lagway Entering Transfer Portal
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Gets Dominated
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Wins Sixth Fight In A Row
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Morgan Charriere Suffers First-Round Knockout Loss
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Gets First-Round Knockout Win
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Lance Gibson Jr. Drops Decision In His UFC Debut
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