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Former Arizona Cardinals quarterback Kyler Murray injured his foot in Week 5 of the 2025 season and never played again after that, opening the door for veteran signal-caller Jacoby Brissett to have the best year of his 10-year NFL career. The 33-year-old veteran played 14 games (12 starts) and completeed 64.9% of his pass attempts for 3,366 yards, 23 touchdowns, and eight interceptions. He went just 1-11 as a starter for the lowly Cardinals, but there's no question that he elevated Arizona's offense from what Murray had shown in the first five games. In a pass-happy offense with the Cardinals often finding themselves down big early, Brissett racked up the passing attempts and aired the football out to finish as the QB15 in fantasy scoring. Murray is now gone, and although the Cardinals signed Gardner Minshew at the position, the expectation is that Brissett will remain the starter in 2026. The Cardinals led the NFL in pass attempts last year, but under new head coach Mike LaFleur, the Cardinals should be a much more run-heavy offense, which means that fantasy managers probably won't be able to count on Brissett putting up similar numbers over a full season in his second year in the desert.--Keith Hernandez
Source: Pro Football Reference
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