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FanDuel MLB DFS Lineup Picks (5/22/18): Daily Fantasy Baseball Advice

I'll be filling in for Justin on this full Tuesday main slate. Chris Sale is the top target at pitcher in cash games, priced $300 below Gerrit Cole and facing a strikeout prone Rays lineup. That will require some punt/low-priced bats to fill in lineups after, several of which will be highlighted in today's articles.

In this article, I will be providing you with my daily fantasy baseball lineup picks for FanDuel on 5/22/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

You can also read more DFS lineup picks for DraftKings and other sports too. If you have any questions or comments, feel free to contact me up on Twitter @DanMarcus3.

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FanDuel DFS Pitchers

Chris Sale- SP, @TB ($11,500)

Sale is the second-highest priced pitcher on the slate, and for good reason. While his strikeout rate is slightly below Cole's, but he has a strong matchup against the Rays. Their lineup features five regulars with a strikeout rate over 25% against LHP and he should have a strong chance at earning a win with the support of the Red Sox offense behind him.  

Luke Weaver- SP, vs. KC ($6,400)

It’s unclear if Weaver has turned a corner after putting together two solid starts but it’s worth taking a chance on that possibility given his price tag and matchup on this slate. While the Royals are a difficult team to rack up strikeouts against, they rank in the bottom third of the league in ISO and wRC+ against RHP.

FanDuel DFS Infielders

Freddie Freeman - 1B, @ PHI ($4,900)

Vince Velasquez has struggled mightily against LHB this season, surrendering 3.04 HR/9 and a .412 wOBA. That’s enough to make Freeman worth his rather high price tag and a cash game building block.

Dee Gordon - 2B, @OAK ($3,100)

Gordon has largely been a disappointment this season with a .330 OBP. However, he has run frequently when he has gotten on base as he has already racked up 16 steals. Cahill hasn’t been a pitcher to target in most cases this season, but one way he has been vulnerable is on the basepaths, already allowing six steals on nine attempts. As a result, it’s likely that if Gordon gets on base, he’ll be on the move and his price tag is very reasonable.

Travis Shaw - 3B, vs. ARI ($3,500)

The magic of Matt Koch has run out and what’s left is a homer prone pitcher who doesn’t miss bats. That makes Shaw, and just about every Brewer, a strong play tonight. Shaw is the choice thanks to his home park accentuating lefty power but Domingo Santana is at near punt pricing which makes him another intriguing option to consider.

Amed Rosario - SS, MIA ($2,400)

Rosario has been quiet and not much of a factor for fantasy purposes this season, but he has had success against LHP in his young career. Through 33 at-bats against them this season, he has recorded a .545 slugging percentage and he had similar success against them last season by slugging .514 in 37 at-bats. To fit both Sale and Freeman into lineups, punt plays will have to be in play and Rosario enters the picture as a result.

FanDuel DFS Outfielders

Austin Meadows - OF, @ CIN ($2,700)

Meadows has flashed both power and speed upside in his very young major league career. He will shift from a largely neutral home park for LHB to one that is a large positive for lefty power. Additionally, he’ll face Matt Harvey, who has allowed a .398 wOBA to LHB this season to go along 2.5 HR/9. While other lefties on the Pirates such as Corey Dickerson and Gregory Polanco are also worth considering, Meadows comes at nearly a 1K discount.

Tyler O’Neill - OF, vs. KC ($2,500)

O’Neill is on an incredible tear, homering in three straight games since getting a chance as a regular in the Cardinals lineup. While it isn't especially likely that streak extends to four games on Tuesday, his obvious power uspide remains underpriced at just $2,500. He’s likely about to take a huge jump in price, so take one more chance with him at a salary relief price tag.

MLB DFS News and Injury Alerts




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REAL-TIME FANTASY NEWS

Al Horford

Tagged as Questionable on Friday
Anthony Edwards

Available for Friday's NBA Cup Game
Harold Fannin Jr.

Questionable for Sunday
Justin Fields

Jets Refusing to Name Starting QB; Justin Fields Expected to Get the Nod
Luke Kennard

Considered Questionable on Friday
Shedeur Sanders

Back in QB2 Role in Week 10
Kayshon Boutte

Ruled Out in Week 10 Against Tampa
Kyshawn George

Downgraded to Questionable on Friday
Rhamondre Stevenson

Officially Ruled Out for Week 10
Tetairoa McMillan

Questionable to Play With Hamstring Injury
Rico Dowdle

Cleared to Play Against Saints
Harold Fannin Jr.

Back at Friday's Practice, on Track to Play Sunday?
DeForest Buckner

Placed on Injured Reserve With Neck Injury
Chris Godwin

Will be Ruled Out in Week 10
Jordan Poole

Out with Quad Strain
Bucky Irving

Still Not Practicing, Won't Play in Week 10
James Cook

a Full-Go for Clash With Dolphins
Nikola Jović

Nikola Jovic Available vs. Hornets
Norman Powell

Available vs. Hornets
Dante Exum

Remains Out vs. Grizzlies
Terrence Shannon Jr.

Questionable With Left Foot Soreness
Jayden Daniels

Will Not Need Surgery on Dislocated Elbow
Randy Brown

Set For UFC Vegas 111 Main Event
Gabriel Bonfim

Looks To Extend His Win Streak
Joseph Morales

A Favorite At UFC Vegas 111
Matt Schnell

Set For UFC Vegas 111 Co-Main Event
Uros Medic

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Muslim Salikhov

Looks For His Fourth Consecutive Win
Chris Padilla

Looks To Remain Unbeaten In The UFC
Chris Kreider

Extends Goal Streak to Four Games
Ismael Bonfim

Looks To Get Back In The Win Column
Nikita Kucherov

Lifts Lightning Past Golden Knights
Marco Tulio

Looks To Remain Undefeated In The UFC
Jalen Chatfield

Injured in Thursday's WIn
Christian Leroy Duncan

Set To Open Up UFC Vegas 111 Main Card
Dougie Hamilton

Exits Early Thursday
Anthony Cirelli

Expected to Be Fine for Saturday
Michael Misa

Sharks Place Michael Misa on Injured Reserve
Aaron Wiggins

Sidelined Friday
Luguentz Dort

 Questionable for Friday
Chet Holmgren

Available for Friday's Matchup With Kings
Zach LaVine

Set to Return Friday
Domantas Sabonis

Questionable to Suit Up Friday
Terance Mann

Considered Probable for Friday's Cup Game
Taurean Prince

Questionable to Play Bulls
Dean Wade

Out Against Wizards
Ayo Dosunmu

Questionable for Friday's Game
Kelly Olynyk

Tagged as Questionable for Friday
Jeremy Sochan

Listed as Questionable for Meeting With Rockets
Steven Adams

May Remain Out Friday
Brock Purdy

Getting Closer, Still Questionable for Week 10
Chris Godwin

Might Not Return Until Late November, Early December
Daniel Jones

Colts Believe in Daniel Jones as Their Franchise QB
Puka Nacua

Practices in Full, Says he Feels Good
A.J. Brown

Listed as Full Participant in Thursday's Practice
Saquon Barkley

Practicing in Full Coming Out of Bye Week
Kyle Tucker

Headlines List of 13 Players to Receive Qualifying Offers
Pete Fairbanks

Becomes a Free Agent
Filip Hallander

Out Against Capitals
Tyson Kozak

Available Versus Blues
Cody Glass

Returns to Action Thursday
Connor Brown

Out on Thursday
Mats Zuccarello

Could Be an Option Friday
Matt Duchene

Remains Out Thursday
Harold Fannin Jr.

Misses Practice With Hamstring Injury
Roope Hintz

a Game-Time Call Thursday
CFB

Luke Fickell Will Return as Wisconsin's Head Coach in 2026
NFL

Antonio Brown Extradited to the United States on Attempted Murder Charge
Bo Bichette

Blue Jays Extend Qualifying Offer to Bo Bichette
Craig Stammen

Named Padres New Manager
K'Andre Miller

Could Return to Action Thursday
Sean Monahan

Injured in Wednesday's Loss
Tyler Bertuzzi

Pots Third-Period Hat Trick Wednesday
Macklin Celebrini

Leads Sharks Past Kraken
Jakob Chychrun

Records Three Assists Wednesday
Alex Ovechkin

Scores 900th Career Goal
Jorge Polanco

Declines his 2026 Option to Become a Free Agent
Adam Gaudette

Available Against Kraken
Scott Laughton

Set for Season Debut Wednesday
Chris Sale

Braves Picking Up Chris Sale's 2026 Option
Michael Thorbjornsen

Poised to Continue Hot Play in Mexico
Davis Riley

Struggling to Find Form Ahead of World Wide Technology Championship
Taylor Montgomery

Leaning on Putter at World Wide Technology Championship
Stephan Jaeger

Offers Strong Value at World Wide Technology Championship
Ben Griffin

Looks to Stay Hot at El Cardonal
Nick Dunlap

Looking to Find His Game at El Cardonal
Wyndham Clark

Searching for Consistency at El Cardonal
Michael Brennan

Aims to Extend Fairytale Start at El Cardonal
Shane Bieber

Staying in Toronto for 2026
Salvador Perez

Agrees to Two-Year Extension With Royals
Trevor Story

Opts in for Remaining Two Years on his Contract
Yu Darvish

to Miss All of 2026 Following Flexor-Tendon Surgery
Shota Imanaga

Becomes a Free Agent
Luis Robert Jr.

White Sox Pick Up 2026 Option on Luis Robert Jr.
CFB

LJ Martin Expected to Play in Top-10 Matchup Against Texas Tech
PGA

LIV Golf Expanding To 72-Hole Format In 2026
Atlanta Braves

Braves Hire Walt Weiss as Their Next Manager
Kris Bubic

Cleared to Begin a Throwing Program
Brandon Woodruff

Declines Mutual Option for 2026
Freddy Peralta

Brewers Exercise 2026 Option on Freddy Peralta
Lucas Giolito

Declines his 2026 Player Option
J.J. Spaun

Finishes Sixth at Procore Championship
PGA

Matti Schmid Finishes Tied for 46th at Baycurrent Classic
Keith Mitchell

Finishes Tied for 10th at Baycurrent Classic
Si Woo Kim

Finishes Tied for 21st at Genesis Championship
Mackenzie Hughes

Misses The Cut at Sanderson Farms Championship
Max Greyserman

Finishes Second at Baycurrent Classic
Austin Eckroat

Finishes Tied for 56th at Baycurrent Classic
Luke Clanton

Finishes Tied for 56th at Bank of Utah Championship
Pete Alonso

Officially Opts Out of his Contract With Mets
Alex Bregman

Opts Out of his Contract With Boston
Edwin Díaz

Edwin Diaz on the Open Market This Winter
Cody Bellinger

Becomes Free Agent After Opting Out
Kyle Larson

Wins His Second NASCAR Cup Series Championship at Phoenix
Ryan Blaney

Concludes the 2025 Season with A Win at Phoenix
William Byron

Strong Championship Effort Ends With Late-Race Flat-Tire Crash
Denny Hamlin

Overtime Four-Tire Call Costs Denny Hamlin the Championship
Chase Briscoe

Championship Bid Never Really Started After Two Tire Failures
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Nearly Steals Phoenix Race
David Onama

Suffers First-Round TKO Loss
Steve Garcia

Scores First-Round TKO Win
Ante Delija

Suffers His First UFC Loss
CFB

Dylan Raiola Suffers Season-Ending Injury
Waldo Cortes-Acosta

Gets Knockout Win
Themba Gorimbo

Drops Decision At UFC Vegas 110
Jeremiah Wells

Gets Back In The Win Column
Yadier del Valle

Remains Undefeated
Isaac Dulgarian

Cut By UFC Following Submission Loss
Daniel Frunza

Still Winless In The UFC
Charles Radtke

Dominates Daniel Frunza
Allan Nascimento

Gets Submission Win
Austin Cindric

is A Driver to Avoid for Phoenix DFS Lineups
Alex Bowman

Could Alex Bowman be A Sneaky Tournament Play for Phoenix?
Noah Gragson

Should DFS Players Roster Noah Gragson At Phoenix?
Erik Jones

Is Erik Jones Worth Rostering for DFS at Phoenix?
Michael McDowell

an Easy Recommendation for DFS at Phoenix
Chase Briscoe

Probably Won't Win the Title
Joey Logano

Could Play Spoiler in Championship Battle at Phoenix
Tyler Reddick

Seeking to End Winless Drought, but Probably Won't Have the Speed
NASCAR

Bubba Wallace Looks to Protect Top-10 Points Finish at Phoenix
Brad Keselowski

Hasn't Been Fast at Phoenix With RFK Racing
Daniel Suarez

With Nothing at Stake, Expect Little From Daniel Suarez
Kyle Busch

Qualifies Well, but Will Probably Finish Worse Than he Starts
Chris Buescher

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Austin Dillon

Looks to Avoid Finishing Last in NASCAR Playoffs
AJ Allmendinger

A.J. Allmendinger Might be a Worthy DFS Option

RANKINGS

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RB
WR
TE
K
DEF
RANKINGS
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1B
2B
3B
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