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FanDuel MLB DFS Lineup Picks (5/22/18): Daily Fantasy Baseball Advice

I'll be filling in for Justin on this full Tuesday main slate. Chris Sale is the top target at pitcher in cash games, priced $300 below Gerrit Cole and facing a strikeout prone Rays lineup. That will require some punt/low-priced bats to fill in lineups after, several of which will be highlighted in today's articles.

In this article, I will be providing you with my daily fantasy baseball lineup picks for FanDuel on 5/22/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

You can also read more DFS lineup picks for DraftKings and other sports too. If you have any questions or comments, feel free to contact me up on Twitter @DanMarcus3.

Featured Promo! Save 50% on any PGA Premium Pass using discount code MASTERS, this week only! Win more with our DFS and Betting Packages, get expert tools and advice from proven winners including the Lineup Optimizer, Research Station, betting/props cheat sheet and more. GAIN FULL ACCESS HERE

FanDuel DFS Pitchers

Chris Sale- SP, @TB ($11,500)

Sale is the second-highest priced pitcher on the slate, and for good reason. While his strikeout rate is slightly below Cole's, but he has a strong matchup against the Rays. Their lineup features five regulars with a strikeout rate over 25% against LHP and he should have a strong chance at earning a win with the support of the Red Sox offense behind him.  

Luke Weaver- SP, vs. KC ($6,400)

It’s unclear if Weaver has turned a corner after putting together two solid starts but it’s worth taking a chance on that possibility given his price tag and matchup on this slate. While the Royals are a difficult team to rack up strikeouts against, they rank in the bottom third of the league in ISO and wRC+ against RHP.

FanDuel DFS Infielders

Freddie Freeman - 1B, @ PHI ($4,900)

Vince Velasquez has struggled mightily against LHB this season, surrendering 3.04 HR/9 and a .412 wOBA. That’s enough to make Freeman worth his rather high price tag and a cash game building block.

Dee Gordon - 2B, @OAK ($3,100)

Gordon has largely been a disappointment this season with a .330 OBP. However, he has run frequently when he has gotten on base as he has already racked up 16 steals. Cahill hasn’t been a pitcher to target in most cases this season, but one way he has been vulnerable is on the basepaths, already allowing six steals on nine attempts. As a result, it’s likely that if Gordon gets on base, he’ll be on the move and his price tag is very reasonable.

Travis Shaw - 3B, vs. ARI ($3,500)

The magic of Matt Koch has run out and what’s left is a homer prone pitcher who doesn’t miss bats. That makes Shaw, and just about every Brewer, a strong play tonight. Shaw is the choice thanks to his home park accentuating lefty power but Domingo Santana is at near punt pricing which makes him another intriguing option to consider.

Amed Rosario - SS, MIA ($2,400)

Rosario has been quiet and not much of a factor for fantasy purposes this season, but he has had success against LHP in his young career. Through 33 at-bats against them this season, he has recorded a .545 slugging percentage and he had similar success against them last season by slugging .514 in 37 at-bats. To fit both Sale and Freeman into lineups, punt plays will have to be in play and Rosario enters the picture as a result.

FanDuel DFS Outfielders

Austin Meadows - OF, @ CIN ($2,700)

Meadows has flashed both power and speed upside in his very young major league career. He will shift from a largely neutral home park for LHB to one that is a large positive for lefty power. Additionally, he’ll face Matt Harvey, who has allowed a .398 wOBA to LHB this season to go along 2.5 HR/9. While other lefties on the Pirates such as Corey Dickerson and Gregory Polanco are also worth considering, Meadows comes at nearly a 1K discount.

Tyler O’Neill - OF, vs. KC ($2,500)

O’Neill is on an incredible tear, homering in three straight games since getting a chance as a regular in the Cardinals lineup. While it isn't especially likely that streak extends to four games on Tuesday, his obvious power uspide remains underpriced at just $2,500. He’s likely about to take a huge jump in price, so take one more chance with him at a salary relief price tag.

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

Martin Necas

Collects an Assist in Game 4 Loss to Golden Knights
Gabriel Landeskog

Scores Only Avalanche Goal in Season-Ending Loss
Carter Hart

Finishes Series-Clincher With 20 Saves
Dylan Coghlan

Continues Unlikely Success Story
Cole Smith

Scores Series-Clincher Tuesday Night
Mark Stone

Nets Another Goal as Golden Knights Finish Off Avalanche
Ludvig Aberg

Looking to Exchange Momentum for a Victory in Fort Worth
Stephan Jaeger

Trending Upward as PGA Heads to Fort Worth
Max Homa

Comes off Awful Putting Performance at PGA Championship
Tony Finau

Faces Different Test at the Colonial
Robert MacIntyre

Seeks Better Beginning in Fort Worth
Tom Hoge

Ups and Downs Could Continue at Colonial
Brian Harman

Not Having the Best Golf Season in 2026
Austin Eckroat

Struggling Too Often Heading to Charles Schwab Challenge
Zach Bauchou

Tries to Keep Momentum Rolling at Colonial
Keegan Bradley

Looking to Rebound at Colonial
Tory Horton

Could Do Some Stuff "Toward the End of Spring"
Patrick Mahomes

Takes Part in First OTA Practice on Tuesday
Los Angeles Chargers

Derwin James Jr. Becomes Highest-Paid Safety for the Second Time in his Career
Chris Brooks

Emerging as Top Handcuff to Stash?
MarShawn Lloyd

Sees Short-Term Value Soar
Jared McCain

Moves into Starting Five
Boston Celtics

Joe Mazzulla Wins Coach of the Year
Jalen Williams

is Ruled Out for Game 5 on Tuesday
Bucky Irving

is Expected to be Ready for Training Camp
Zion Williamson

to See More Versatile Role
Parker Washington

Jaguars Think Parker Washington Can Replicate Second-Half Production
Cleveland Cavaliers

Kenny Atkinson to Remain Cavaliers Head Coach Next Season
Josh Jacobs

Arrested on Five Charges, Booked Into Jail
Claude Giroux

Planning to Return for 20th NHL Campaign
Josh Sweat

Cardinals Receiving Trade Calls on Josh Sweat
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Tetairoa McMillan

Working With the Training Staff on Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Mackenzie Blackwood

in Net for Game 4 Against Golden Knights
Valeri Nichushkin

a Game-Time Call Tuesday
Nathan MacKinnon

Will Suit Up Tuesday
Jerome Ford

Is it Time for Dynasty Managers to Drop Jerome Ford?
John Metchie III

Poised for Breakout Season with New Team in 2026?
Jalen Milroe

Is Jalen Milroe Still Worth Stashing in Dynasty Formats Entering 2026?
Kyle Pitts Sr.

Is Kyle Pitts Sr. a Dynasty Sell-High Candidate Coming Off Breakout Season?
Nico Collins

Agrees to Contract Adjustment with Texans
Chris Brooks

Carries Buy-Low Dynasty Appeal into 2026
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
NFL

NFL Unlikely to Expand to 18 Regular-Season Games by 2027
Sahith Theegala

Searching For Swing at Charles Schwab Challenge
Lamar Jackson

in Attendance at OTAs This Week
Bucky Irving

Expected Back in the Summer or Fall
CFB

DJ Lagway Looking to Rebound at Baylor
CFB

Josh Hoover Tasked With Leading Indiana Back to the Playoffs
CFB

Braylon Staley the Next 1,000-Yard Tennessee Receiver?
Jalen Tolbert

Does Jalen Tolbert Have Short-Term Dynasty Appeal?
CFB

Ahmad Hardy's Return Timeline Remains Unclear
Travis Etienne Jr.

Is Travis Etienne Jr. Still a Dynasty RB1 Following Change of Scenery?
Evan Mobley

Finishes Season-Ending Loss With 15 Points
James Harden

Wants to Stay in Cleveland
Donovan Mitchell

Remains Committed to Cavaliers
Mikal Bridges

Cools Off in Game 4 Against Cavaliers
OG Anunoby

Active on Both Ends in Blowout Win
Karl-Anthony Towns

Leads Knicks in Scoring During Series-Clincher
Jalen Brunson

Named Eastern Conference Finals MVP
Ivan Demidov

Contributes an Assist in Losing Effort
Lane Hutson

Records Power-Play Goal in Game 3 Loss
Frederik Andersen

Enjoys Another Easy Night at the Office in Game 3
Shayne Gostisbehere

Scores First Postseason Goal
Taylor Hall

Ends Four-Game Goal Drought
Andrei Svechnikov

Scores Game 3 Winner in Overtime
Gage Jump

Athletics to Promote Top Pitching Prospect Gage Jump to Major Leagues
Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
Dennis Schröder

Dennis Schroder is Ruled Out for Game 4 on Monday
Michael Porter Jr.

Nets Could Trade Michael Porter Jr.
Ajay Mitchell

is Ruled Out for Game 5
Jalen Williams

is Tagged as Questionable for Game 5
Valeri Nichushkin

Nathan MacKinnon, Valeri Nichushkin Uncertain for Game 4
Oliver Kapanen

Sitting as Healthy Scratch Monday
Max Domi

Out Indefinitely Due to Offseason Surgery Complications
Dylan Cease

Heading to Injured List With Hamstring Injury
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
Denny Hamlin

Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Isaiah Hartenstein

Provides Steady Production in Defeat
Chet Holmgren

Has a Quiet Offensive Night on Sunday
Shai Gilgeous-Alexander

Held Under 20 Points in Game 4
Stephon Castle

Hands Out Six Assists in Game 4 Win
Devin Vassell

Tallies 13 Points in Game 4 Win
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
MLB

Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
NASCAR

Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
MLB

Orioles-Tigers Game Postponed on Saturday
MLB

Rays-Yankees Postponed on Saturday
Mickey Moniak

Heads to Injured List With Ankle Sprain
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
Robby Snelling

Will Undergo Tommy John Surgery
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF