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Updated Week 6 Flex Rankings (Top 200)

Our updated Week 6 fantasy football Flex rankings (RB, WR, TE) for 2021. Follow these fantasy football FLEX ranks when setting your Week 6 lineups.

Welcome to Week 6 RotoBallers. Below are our updated consensus Week 6 Flex rankings for fantasy football, including some running notes on relevant injuries, player news and rankings updates. These Flex rankings are geared towards making decisions for your Flex spot (RB/WR or RB/WR/TE), which in most leagues consists of running backs, wide receivers and in many cases tight ends as well:

These rankings are a consensus from four of our lead fantasy football columnists - Nick MarianoPierre Camus, Brandon Murchison and Scott Engel - who have all analyzed the NFL matchups and game slates for Week 6.

And in case you weren't aware, our very own Nick Mariano was ranked #11 overall in 2018 out of ~120 industry experts, and was ranked #9 overall the year before. So be sure to follow his rankings every week!

Be sure to check all of our fantasy football rankings for 2025:

 

Week 6 Fantasy Football Flex Rankings

You can also see our full Week 6 ranks for PPRHalf-PPR and Standard scoring.

Last updated on Sunday 10/17 at 11:00 am ET:

FLEX Rank Player Name Pos
1 Derrick Henry RB
2 Davante Adams WR
3 Austin Ekeler RB
4 Jonathan Taylor RB
5 Stefon Diggs WR
6 Najee Harris RB
7 Travis Kelce TE
8 Tyreek Hill WR
9 Kareem Hunt RB
10 Cooper Kupp WR
11 Ezekiel Elliott RB
12 James Robinson RB
13 Aaron Jones RB
14 Justin Jefferson WR
15 DeAndre Hopkins WR
16 D'Andre Swift RB
17 Ja'Marr Chase WR
18 D.J. Moore WR
19 Terry Mclaurin WR
20 Keenan Allen WR
21 D.K. Metcalf WR
22 Joe Mixon RB
23 Diontae Johnson WR
24 Antonio Gibson RB
25 Dalvin Cook RB
26 Mike Williams WR
27 Robert Woods WR
28 CeeDee Lamb WR
29 Chris Godwin WR
30 Darrell Henderson Jr. RB
31 Courtland Sutton WR
32 Mike Evans WR
33 DeVonta Smith WR
34 Chase Claypool WR
35 Marquise Brown WR
36 Michael Pittman Jr. WR
37 Antonio Brown WR
38 A.J. Brown WR
39 Adam Thielen WR
40 Amari Cooper WR
41 Mark Andrews TE
42 Leonard Fournette RB
43 Chuba Hubbard RB
44 Dawson Knox TE
45 Brandin Cooks WR
46 Tyler Lockett WR
47 Josh Jacobs RB
48 Myles Gaskin RB
49 Emmanuel Sanders WR
50 Darren Waller TE
51 Devontae Booker RB
52 Tee Higgins WR
53 Tyler Boyd WR
54 Khalil Herbert RB
55 Kadarius Toney WR
56 Jakobi Meyers WR
57 Chase Edmonds RB
58 Jaylen Waddle WR
59 Darrel Williams RB
60 Zack Moss RB
61 Marvin Jones Jr. WR
62 Julio Jones WR
63 Sterling Shepard WR
64 Damien Harris RB
65 Melvin Gordon III RB
66 Javonte Williams RB
67 Allen Robinson II WR
68 Amon-Ra St. Brown WR
69 Dalton Schultz TE
70 Odell Beckham Jr. WR
71 Tim Patrick WR
72 Latavius Murray RB
73 Noah Fant TE
74 Mecole Hardman WR
75 Tony Pollard RB
76 Laviska Shenault Jr. WR
77 T.J. Hockenson TE
78 Mike Gesicki TE
79 Rondale Moore WR
80 Darnell Mooney WR
81 Alex Collins RB
82 Hunter Henry TE
83 Cole Beasley WR
84 Hunter Renfrow WR
85 Jamaal Williams RB
86 Zach Ertz TE
87 Henry Ruggs III WR
88 Robby Anderson WR
89 Christian Kirk WR
90 James Conner RB
91 Quez Watkins WR
92 Alexander Mattison RB
93 J.D. McKissic RB
94 AJ Dillon RB
95 Jalen Reagor WR
96 Tyler Higbee TE
97 Kendrick Bourne WR
98 A.J. Green WR
99 Ricky Seals-Jones TE
100 Devin Singletary RB
101 Nyheim Hines RB
102 Van Jefferson WR
103 Kenneth Gainwell RB
104 Bryan Edwards WR
105 Nelson Agholor WR
106 Miles Sanders RB
107 Jared Cook TE
108 Dan Arnold TE
109 Randall Cobb WR
110 Rashod Bateman WR
111 David Njoku TE
112 Kalif Raymond WR
113 Sony Michel RB
114 DeSean Jackson WR
115 Donovan Peoples-Jones WR
116 David Johnson RB
117 Terrace Marshall Jr. WR
118 Adam Humphries WR
119 Zach Pascal WR
120 Cedrick Wilson Jr. WR
121 K.J. Osborn WR
122 Evan Engram TE
123 Allen Lazard WR
124 Tyler Conklin TE
125 Jonnu Smith TE
126 Gabriel Davis WR
127 Preston Williams WR
128 Robert Tonyan TE
129 Brandon Bolden RB
130 Giovani Bernard RB
131 Chris Evans RB
132 Demarcus Robinson WR
133 Darius Slayton WR
134 Cameron Brate TE
135 Malcolm Brown RB
136 DeAndre Carter WR
137 Gerald Everett TE
138 C.J. Uzomah TE
139 Cole Kmet TE
140 Rashard Higgins WR
141 Chris Conley WR
142 Mark Ingram II RB
143 Kenyan Drake RB
144 Josh Reynolds WR
145 Tavon Austin WR
146 Jeremy McNichols RB
147 Austin Hooper TE
148 Mo Alie-Cox TE
149 Chester Rogers WR
150 James Washington WR
151 Anthony Firkser TE
152 Ray-Ray McCloud WR
153 Jerick McKinnon RB
154 Parris Campbell WR
155 Freddie Swain WR
156 John Ross WR
157 Ronald Jones II RB
158 Devin Duvernay WR
159 Demetric Felton WR
160 Byron Pringle WR
161 Jamal Agnew WR
162 Jack Doyle TE
163 Marlon Mack RB
164 Carlos Hyde RB
165 Jalen Guyton WR
166 Blake Jarwin TE
167 Cameron Batson WR
168 Eric Ebron TE
169 Collin Johnson WR
170 Pat Freiermuth TE
171 Greg Ward WR
172 Rhamondre Stevenson RB
173 Trinity Benson WR
174 Chris Moore WR
175 Marcus Johnson WR
176 KhaDarel Hodge WR
177 Kendall Hinton WR
178 Salvon Ahmed RB
179 Albert Wilson WR
180 Donald Parham Jr. TE
181 Anthony Schwartz WR
182 D'Ernest Johnson RB
183 N'Keal Harry WR
184 Tyler Johnson WR
185 O.J. Howard TE
186 Zay Jones WR
187 Demetrius Harris TE
188 Josh Gordon WR
189 James Proche II WR
190 Auden Tate WR
191 Tommy Tremble TE
192 Ian Thomas TE
193 Devonta Freeman RB
194 Ashton Dulin WR
195 Larry Rountree III RB
196 Kyle Rudolph TE
197 Ty'Son Williams RB
198 Will Dissly TE
199 Pharaoh Brown TE
200 Jordan Akins TE


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More Weekly Lineup Prep


Check out all of RotoBaller's fantasy football rankings. Staff rankings are updated regularly for all positions and include standard formats, PPR scoring, tiered rankings and dynasty leagues.




POPULAR FANTASY TOOLS

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REAL-TIME FANTASY NEWS

CeeDee Lamb

Unlikely to Play in Week 4 on Sunday Night
Trea Turner

Could Return for Final Regular-Season Series
Kyle Tucker

Unlikely to Return Until at Least Wednesday
Tyrone Tracy Jr.

to Miss Time With Dislocated Shoulder
Ryan Blaney

Advances to the Round of 8 In the Playoffs After Winning at New Hampshire
William Byron

Earns A New Career-Best Finish of Third at New Hampshire
Chase Elliott

Scores Top-Five Finish at New Hampshire
Kyle Larson

Shows Speed and Finishes in the Top 10 at New Hampshire
NASCAR

Bubba Wallace's Handling Struggles Leaves him Behind the Playoff Cut Line
James Conner

Officially Out for Remainder of 2025 Season
Najee Harris

Out for Rest of Season With Torn Achilles
Ricky Pearsall

Torches the Cardinals Secondary on Sunday For 117 Yards
CFB

ACC Fines Syracuse $25,000 for "Feigning of Injuries"
CeeDee Lamb

Believed to Have a High-Ankle Sprain
Tyler Kleven

Suffers Undisclosed Injury Against Maple Leafs
Nicolas Hague

Injured on Sunday
Logan Cooley

Hurt in Preseason Game
Andre Burakovsky

Misses Practice With Lower-Body Injury
Jared McCann

Considered Day-to-Day
Jalen Chatfield

Unlikely to Play During Preseason
Josh Berry

Recovers from Spin to Finish Second
Joey Logano

Delivers Playoff Speed After Regular-Season Mediocrity
Denny Hamlin

Remains a Solid Bet to Advance in Playoffs
Tyler Reddick

Brake Brakedown Diminishes Tyler Reddick's Playoff Hopes
Ross Chastain

Loses Ground in Playoff Race Despite Top-10 Finish
CFB

Steve Angeli Will Miss Remainder of 2025 Season With Torn Achilles
Puka Nacua

Targeted 15 Times, Goes Over Century Mark in Loss to Eagles
Kenneth Walker III

Finds End Zone Twice in Blowout of Saints
A.J. Brown

Breaks Out of Early-Season Slump With Monster Week 3
Corbin Carroll

Joins 30-30 Club on Sunday
Tyrone Tracy Jr.

Ruled Out for Remainder of Week 3 Due to Shoulder Injury
Brandon Woodruff

has Moderate Lat Strain
Luther Burden III

Tops 100 Receiving Yards in Week 3, Scores First NFL Touchdown
James Conner

Ankle Injury Severe Enough to End His Season?
Courtland Sutton

Bounces Back With Monster Week 3 Performance
Tyrone Tracy Jr.

Questionable to Return With Shoulder Injury
Mac Jones

Aggravates PCL Sprain in Week 3 Win
CeeDee Lamb

Believes That He Can Play in Week 4
Najee Harris

Tests Indicate Najee Harris Tore Achilles
Caleb Williams

Throws for Four Touchdowns in Stellar Outing Sunday
CeeDee Lamb

Avoids Major Ankle Injury in Week 3 Loss
Najee Harris

Achilles Injury Confirmed for Najee Harris
Jeremy Peña

Jeremy Pena to Get Imaging Done
Yordan Alvarez

Won't Make Final Road Trip
Nico Collins

Goes Over 100-Yard Mark
Anthony Davis

Participates in Five-on-Five Games
Cedric Coward

"100% Cleared" for Basketball Activities
Trevor Megill

Unlikely to Return Until Playoffs
Brandon Woodruff

Goes on 15-Day Injured List With Lat Strain
CJ Abrams

Out With Jammed Shoulder on Sunday
Wyatt Langford

Back in Lineup on Sunday
Charlie Morton

Designated for Assignment
Ryan Blaney

the Favorite to Win at New Hampshire
Joey Logano

Wins Pole, Is Confident Heading Into New Hampshire Race
Christopher Bell

Is Christopher Bell The No-Brainer DFS Pick at New Hampshire?
Denny Hamlin

Always Strong at New Hampshire
Mike Trout

Hits 400th Career Home Run
William Byron

has Never Finished in the Top 10 at New Hampshire
NASCAR

Bubba Wallace Could Contend at New Hampshire This Weekend
Austin Cindric

Has Potential at New Hampshire
Kyle Larson

a Strong DFS Option, Inconsistency Gives Reason to Doubt him
Chase Elliott

Recent Speed Downturn Could Continue at Loudon
Chase Briscoe

Looks Slower at Loudon Than in the Round of 16
Tyler Reddick

Possibly Distracted by Contract Costs
CFB

Steve Angeli Will Miss Significant Time
William Contreras

Exits With Hand Injury, X-Rays Negative
Cal Raleigh

Breaks Mariners Single-Season Home Run Record
Giancarlo Stanton

Belts 450th Career Home Run
CFB

Thomas Castellanos OK After Injury Scare
CFB

LaNorris Sellers Upgraded to Probable for Saturday's Tilt Against Missouri
Will Smith

Dealing with Fractured Hand
Jaccob Slavin

Remains Sidelined Saturday
Max Domi

Expected to Practice Sunday
Andrei Vasilevskiy

Sits Out Practice
Pablo López

Pablo Lopez Goes to Injured List
Tylor Megill

Likely to Require Tommy John Surgery
CFB

Behren Morton Ruled Out vs. Utah
CFB

Behren Morton Exits with Possible Concussion
Stuart Skinner

Determined to Improve After Shedding Weight
Jeremy Lauzon

Dealing With an Injury
Jack Eichel

Returns to Practice
Wyatt Langford

Day-to-Day With Side Tightness
Bryan Woo

Exits With Pectoral Tightness on Friday
Alec Bohm

Phillies Reinstate Alec Bohm on Friday
Matt Coronato

Matthew Coronato Expected to Make a Big Impact This Season
Johnathan Kovacevic

Out Indefinitely
Kevin Hayes

to Be Re-Evaluated in About a Month
Evgeni Malkin

Not Thinking About Retirement
UTA

Alex Kerfoot Out Week-to-Week
Zeev Buium

Misses Practice With Upper-Body Injury
Artemi Panarin

Sustains Lower-Body Injury in Training Camp
Brooklyn Nets

Yuri Collins Headed to Brooklyn
Charlotte Hornets

Hornets Sign Keyontae Johnson
Dennis Smith Jr.

Agrees to One-Year Deal With Mavericks
Tyler Herro

Undergoing Foot/Ankle Surgery
William Eklund

Back at 100 Percent in Training Camp
Macklin Celebrini

Battling an Illness
CFB

LaNorris Sellers Upgraded to Probable for Saturday's Tilt Against Missouri
Malcolm Brogdon

Landry Shamet and Malcolm Brogdon Both Staying with the Knicks?
Detroit Pistons

Charles Bediako Agrees to a Training Camp Deal with Detroit
Anthony Davis

Recovering From Eye Surgery, Uncertain for Training Camp
Charlotte Hornets

DaQuan Jeffries Waived by the Hornets
CFB

Eric Singleton Jr. Questionable For Saturday
NBA

Trevelin Queen Joins Chinese Team
Damian Lillard

Not Rushing His Return
Brooklyn Nets

Keon Johnson Waived by Nets
CFB

LaNorris Sellers to Play Against Missouri?
CFB

Kaidon Salter Expected To Start for Colorado on Saturday
Trey Jemison III

Joins Knicks on Two-Way Contract
Kevin McCullar Jr.

Signs New Two-Way Deal With Knicks
Matt Ryan

Returns to Knicks on Exhibit 10 Contract
New York Knicks

Alex Len Signs Exhibit 9 Deal With Knicks
Nickeil Alexander-Walker

Expected to Take on Larger Offensive Role With Hawks
Thomas Sorber

Undergoes Surgery
CFB

Diego Pavia Refutes Report of Seeking Seventh Collegiate Season

RANKINGS

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TE
K
DEF
RANKINGS
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1B
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OF
SP
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