September 5, 2025
Buffalo Bills wide receiver
Joshua Palmer will make his debut with the team this Sunday after spending the first four years of his career with the Los Angeles Chargers. It won't be an easy Week 1 matchup for Palmer, who will face a sturdy Baltimore Ravens secondary. Although the 25-year-old is coming off his second straight season with fewer than 40 catches, the Bills brought him in to serve as one of their top three WRs alongside
Khalil Shakir and
Keon Coleman. Considering Palmer didn't exceed 72 catches, 769 yards, or four touchdowns in any season with
Justin Herbert as his quarterback, he isn't garnering much hype going into 2025. Palmer's probably not on most fantasy managers' radars for a meeting with the Ravens, but it's worth monitoring how often
Josh Allen targets him in their first game together this week.
--Connor ByrneSource: ESPN
September 5, 2025
Buffalo Bills tight end
Dalton Kincaid endured a sophomore slump last season. After amassing 73 catches for 673 yards and two touchdowns over 16 games as a rookie, the former first-rounder posted 44-448-two in 13 contests in 2024. A knee injury hampered Kincaid, who is healthy heading into the new season and will face off against a talent-rich Baltimore Ravens defense in the opener this Sunday. Kincaid took on the Ravens twice a year ago and produced mixed results. He caught five of seven targets for 47 yards in a Week 4 loss and secured one of two targets for 11 yards in a divisional-round victory. While Kincaid is a risky choice for Sunday, the 25-year-old has more upside than he offered last season. There is potential for Kincaid to become a reliable TE1 for fantasy managers in 2025.
--Connor ByrneSource: ESPN
September 5, 2025
Buffalo Bills wide receiver
Keon Coleman (groin) enters his second NFL season as a breakout candidate. The 2024 second-round pick only caught 29 of 57 targets in 13 games last season, but he averaged 19.2 yards per grab and found the end zone four times. Coleman's stock appeared to be on the rise before he suffered a wrist injury in Week 9. He sat out for over a month as a result, and he was a non-factor upon his return. Despite ending 2024 on a sour note, Coleman has drawn rave reviews this summer for his performance in practice. It's anyone's guess if that will translate in the regular season, which begins Sunday against the Baltimore Ravens. The 6-foot-4, 215-pounder has been limited in practice with a groin injury, but it shouldn't prevent him from playing. While Coleman may still carry too much risk for fantasy managers to trust this week, it'll be a positive sign if he's productive against an imposing Baltimore secondary.
--Connor ByrneSource: Buffalo Bills
September 5, 2025
Cleveland Browns All-Pro pass-rusher Myles Garrett (hip) returned to practice on Friday and was removed from the final Week 1 injury report, meaning he'll play on Sunday against the division-rival Cincinnati Bengals, barring a setback, according to Mark Kay Cabot of The Cleveland Plain Dealer. Garrett did not practice on Thursday due to his hip injury, but it was likely more of a rest day for the veteran pass-rusher. The Browns are going to have a tough time slowing down quarterback
Joe Burrow and one of the best offenses in the league this weekend, but having Garrett active certainly helps. The 29-year-old six-time Pro Bowler and four-time All-Pro has 102.5 sacks in his eight years in the league and should be locked into all starting IDP lineups this weekend.
--Keith HernandezSource: The Cleveland Plain Dealer - Mary Kay Cabot
September 5, 2025
After the departure of
Stefon Diggs,
Khalil Shakir took over as the Buffalo Bills' No. 1 wide receiver in 2024. The slot standout led the team in catches (76), targets (100), and yards (821) while finishing with four touchdowns over 15 games last year. Shakir is the favorite to serve as quarterback
Josh Allen's top target again this season, which begins Sunday against the Baltimore Ravens. The 6-foot, 190-pounder took on Baltimore twice last year and combined for 10 grabs on 13 targets, 129 yards, and no TDs, though an ankle injury cut his first meeting with the Ravens short. More recently, Shakir dealt with a high-ankle sprain throughout August, but he has been a full go in practice since Wednesday and should play a prominent role on Sunday. Baltimore has a strong secondary on paper, and both a lack of TDs (seven in three years) and a lack of usage in two-WR sets could continue to limit Shakir's upside. Nevertheless, Shakir is a sure-handed pass catcher who totaled six-plus receptions 10 times last season (including all three playoff games), and Allen figures to look in his direction often on Sunday.
--Connor ByrneSource: ESPN
September 5, 2025
Buffalo Bills running back
James Cook is coming off a 2024 campaign in which he unexpectedly tied for the NFL lead with 16 rushing touchdowns after tallying just two in the previous season. He also surpassed 1,000 yards on the ground for the second year in a row, but fantasy managers may have to temper expectations in Week 1. Cook is set to battle the Baltimore Ravens, who boasted the league's top-ranked run defense last season, when the teams kick off Sunday. The Ravens held opposing rushers to a paltry 3.6 yards per carry - a far cry from Cook's 4.9 YPC. Cook faced the Ravens twice in 2024 and combined for 106 yards on 26 carries, four catches for another 24 yards, and zero scores. The explosive 25-year-old enters 2025 as a high-end RB2 in fantasy, but with the Ravens standing in his way, Cook may not storm out of the gates in the opener.
--Connor ByrneSource: ESPN
September 5, 2025
Buffalo Bills quarterback
Josh Allen is a one-man wrecking crew, but he'll face a stiff test in Sunday's season opener against the Baltimore Ravens. While the reigning MVP tormented his share of opponents in 2024, he didn't post gaudy numbers in two meetings with the Ravens - a Week 4 loss and a divisional-round win. Allen combined to go a modest 32-for-51 (63%) for 307 yards and no touchdown passes or interceptions in those contests. With 41 yards on 15 carries, the dual-threat superstar averaged under 3.0 YPC, though he did find the end zone twice in the Bills' postseason triumph. Baltimore allowed the second-most passing yards in the league last season, but its defense improved dramatically when All-Pro Kyle Hamilton shifted to a deep safety role in Week 11. The Ravens have since remade their secondary with the additions of first-round safety Malaki Starks, who will start alongside Hamilton, as well as cornerbacks Jaire Alexander (knee) and Chidobe Awuzie in free agency. With corners Marlon Humphrey and Nate Wiggins returning, the Ravens' defensive backfield is stacked on paper. That's not ideal for Allen, yet he has made plenty of talented defenses look bad in the past. Fantasy managers will have to hope he does it again in Week 1.
--Connor ByrneSource: ESPN
September 5, 2025
Los Angeles Chargers offensive guard Mekhi Becton (illness) has been added to the team's injury report due to an illness and is now questionable to play on Friday in Brazil for the Week 1 divisional clash against the Kansas City Chiefs, according to the team. Becton probably has a decent shot at suiting up, but if he were to be inactive, it would be a concern for the Chargers offense against a Chiefs defense that was one of the best in football a year ago. The 26-year-old former first-rounder of the New York Jets in 2020 out of Louisville was a bust for Gang Green due to injuries, but he excelled last year with the Philadelphia Eagles after moving to guard and parlayed it into a two-year, $20 million deal in the offseason with the Bolts. If Becton doesn't play on Friday, it will be a small downgrade for Chargers running backs
Omarion Hampton and
Najee Harris.
--Keith HernandezSource: Los Angeles Chargers
September 5, 2025
Indianapolis Colts head coach Shane Steichen said that running back
Tyler Goodson (elbow) is questionable for the Week 1 regular-season opener on Sunday against the Miami Dolphins, according to Mike Chappell of FOX 59. Goodson was able to put in limited practices this week, so he has a pretty good shot of suiting up this weekend for the season opener. However, even if he's deemed healthy enough to play, the 24-year-old might be the RB3 for Indy behind starter
Jonathan Taylor and rookie
DJ Giddens. Goodson can likely be ignored in most fantasy leagues unless Taylor misses time with an injury in 2025. The Iowa alum had 32 carries in his second NFL season in 2024 and ran for 153 yards and one touchdown in 16 games (no starts), adding 11 catches for 61 yards and one touchdown through the air.
--Keith HernandezSource: FOX 59 - Mike Chappell
September 5, 2025
Green Bay Packers head coach Matt LaFleur said he expects wide receiver
Jayden Reed (foot) to practice again on Friday, although he could be limited for the second straight day, according to Rob Demovsky of ESPN. Reed is battling through a Jones fracture and did not take part in the first practice of the week, but he was upgraded to limited on Thursday, giving him a shot to play in Week 1 against the division-rival Detroit Lions. It sounds as though Reed might not be able to be a full-go on Friday, though, suggesting he could draw a questionable tag for the regular-season opener this Sunday. Still, the 25-year-old has a shot to be active this weekend. If Reed does suit up, his reps could be limited, making him an even bigger boom/bust risk as a WR4/flex in fantasy lineups. If he's out,
Romeo Doubs would become a more attractive flex.
--Keith HernandezSource: ESPN.com - Rob Demovsky
September 5, 2025
Cleveland Browns edge rusher Myles Garrett (hip) returned to practice Friday after sitting out the day prior. The Texas A&M product was a surprise addition to Thursday's practice report with a hip injury, but it doesn't appear to be a significant issue, as he was back out there the following day. It's worth noting that the capacity in which Garrett is practicing has yet to be detailed. Still, it's an encouraging sign for his status in this weekend's matchup with the visiting Cincinnati Bengals. Garrett owners will want to keep an eye out for any news about him over the next day or so, and his snaps may be limited this weekend if the ailment lingers. If that's the case, teammates Isaiah McGuire, Joe Tryon-Shoyinka, and even Cameron Thomas could see extended play in Week 1.
--Alex CiullaSource: NFL.com
September 5, 2025
Tampa Bay Buccaneers head coach Todd Bowles has officially ruled out wide receiver
Chris Godwin (ankle) for Week 1 of the regular season this Sunday versus the division-rival Atlanta Falcons, according to Greg Auman of FOX Sports. The Bucs also ruled out offensive tackle Tristan Wirfs (knee). Both Godwin and Wirfs are expected to miss at least the first couple of weeks of the season, with Godwin potentially not making it back until Week 5 or later after suffering a gruesome dislocated ankle in Week 7 of last year. The 29-year-old should be stashed in most fantasy leagues, but it's going to be some time until we see him make his 2025 debut since he has not practiced at all since having surgery on his ankle. In the meantime, rookie first-rounder
Emeka Egbuka figures to see a steady stream of targets behind
Mike Evans with
Jalen McMillan (neck) on Injured Reserve.
--Keith HernandezSource: FOX Sports - Greg Auman
September 5, 2025
Per the team, Buffalo Bills kicker
Tyler Bass (hip, groin) will not practice on Friday. Bass will miss his second consecutive practice after logging a limited session to start the week. The 28-year-old has been dealing with a lingering hip injury this offseason that he has been unable to shake. While Bass hasn't been ruled out for Sunday's meeting with the Baltimore Ravens, it'd undoubtedly be a surprise to see him suit up at this point -- particularly with Buffalo's signing of veteran kicker
Matt Prater to the practice squad on Thursday. Fantasy managers can't yet rule him out, but with a Sunday night kickoff on tap, a contingency plan at the position is a sound strategy. Bass is ranked as a top ten option at his position per RotoBaller's Week 1 rankings.
--Alex CiullaSource: NFL.com
September 5, 2025
Minnesota Vikings offensive lineman Christian Darrisaw (knee) logged a DNP on Thursday for the team's first official practice ahead of their Week 1 tilt with the Chicago Bears on Monday Night Football. Darrisaw has been recovering from a significant knee injury he suffered last September and has reportedly looked "really good," according to head coach Kevin O'Connell. Still, Minnesota is playing it safe with its franchise tackle, and rightfully so, as he's an integral part of their offensive line. There's a chance the Virginia native is still able to suit up on Monday, but he'll likely need to log at least a limited session this week before doing so. Fellow OL Justin Skule would work in Darrisaw's stead if he were unable to play.
--Alex CiullaSource: Minnesota Vikings
September 5, 2025
New York Jets head coach Aaron Glenn said he expects cornerback Sauce Gardner (leg) to suit up for the Week 1 season opener on Sunday against the Pittsburgh Steelers, according to Zack Rosenblatt of The Athletic. Gardner was limited in the team's first official practice of the year on Wednesday before upgrading to a full practice session on Thursday. It's possible that the Jets ease the 25-year-old defensive back into his starting role to kick off the season this weekend, but he should be out there. It's good news for a Jets defense/special teams unit that should be considered a top-10 fantasy play in Week 1 against aging quarterback
Aaron Rodgers. When fully healthy, Gardner is considered one of the best lockdown cornerbacks in the NFL.
--Keith HernandezSource: The Athletic - Zack Rosenblatt
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