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DraftKings Daily Fantasy Baseball Picks (5/22/18): MLB DFS Lineups

We have a monster 15-game slate to break down today, and there are some great options across the board. There are a few high-priced pitchers on the slate you should be looking to pay up for, along with plenty of bats you want to jam into your lineups.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 5/22/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @DFS_Tom.

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DraftKings Starting Pitchers

Chris Sale - P, BOS @ TB (DK - $13,100)

Chris Sale is the most expensive pitcher on the slate, and I give him the edge over Cole for a few reasons, so let's take a look. Sale has pitched seven or more innings in three of his last four starts, compared to Cole's one game at seven or more innings in his last four starts. That might not seem like a big deal, but when you are paying up for a pitcher in this price range, you want to know they are going deep into the game, and not get pulled early. Sale is up against the Rays, who have a 23.5% strikeout rate vs left-handed pitcher this season, which is 11th worst in the league. This is a nice positive park shift in Sale's favor, as he is in Tampa and away from Fenway Park. Sale has racked up nine or more strikeouts in three of his last four starts, including two games with 12 or more.

Caleb Smith - P, MIA @ NYM (DK - $6,400)

Smith is a cheaper option at pitcher, who has a few factors going in his favor tonight. First off, he is up against the Mets, who have a 26.7% strikeout rate vs left-handed pitchers, which is third worst in the league. The first time Smith faced the Mets this season, he put up seven strikeouts in five innings, while allowing three earned runs. If he is able to limit the earned runs and squeeze out one more inning, we could be looking at some serious value for a pitcher who is under $7K. Great park factor in his favor should allow him to limit the damage.

 

DraftKings Infielders

Josh Bell - 1B, PIT @ CIN (DK - $4,100)

Bell and the Pirates will be in Cincinnati to face Matt Harvey, who will be making his first start at home for the Reds. This is one of the best hitter's parks in the league, and with how bad Harvey is, this likely won't end well. Bell comes in with a .314 wOBA and a .138 ISO vs right-handed pitchers this season, which is good, but not great, so use him in a stack compared to solo.

Jed Lowrie - 2B, OAK vs SEA (DK - $4,200)

Lowrie comes into this game with a .424 wOBA and a .273 ISO vs right-handed pitchers this season, which are truly great numbers for a second baseman. He is up against Mike Leake, who is giving up a .363 wOBA to lefties, along with 1.01 HR/9 this season. Some good numbers to pick on and Oakland can make a sneakier stack tonight.

Travis Shaw - 3B, MIL vs ARI (DK - $4,500)

Shaw is an absolute monster when facing right-handed pitchers this season, specifically at home this season as he has a .421 wOBA and a .326 ISO. Those are some massive numbers and we could easily be looking at a home run tonight, as he has one last night, and the last time he faced Matt Koch, back on the 16th of this month. Lot of things lining up for him tonight and really like a Brewers stack in GPPs.

Miguel Rojas - SS, MIA @ NYM (DK - $3,100)

Rojas offers a bit of salary relief on this slate and despite his lower price, he has some solid numbers as well. This season he has a .326 wOBA and a .160 ISO vs right-handed pitchers, which are solid numbers for a player on one of the weaker teams in the league. He has two home runs in his last 10 games and had one home run when he faced Zack Wheeler earlier this season #BvP.

 

DraftKings Outfielders

Mookie Betts - OF, BOS @ TB (DK - $6,000)

Betts is the most expensive hitter on the entire slate, but yeah...he is crushing it right now. Over his last 10 games, he has two home runs, six doubles, five RBIs, and 17 total hits. With that kind of production, you should be looking to get him into your lineups really anytime he is on the slate. Now his production will cool down at some point, but if he is this hot, you don't want to pass him up.

Leonys Martin - OF, DET @ MIN (DK - $3,800)

Martin is back from his injury, and even though he is cold right now, he has a good opportunity to bounce back. He comes into this game with a .384 wOBA vs right-handed pitchers and has hit four of his five home runs against them this season. He is up against Lance Lynn, who is giving up a horrendous, .446 wOBA to lefties this season, along with 2.09 HR/9.

 

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

OG Anunoby

Starting on Tuesday
Tobias Harris

May Remain in Motown
Jalen Duren

Pistons Eager to Keep Jalen Duren
Chris Kirk

Continues Search For Putting Form at TPC Craig Ranch
NBA

Jason Kidd Fired as Mavericks Head Coach
De'Aaron Fox

Officially Listed as Questionable for Game 2 Against Thunder
Rasmus Hojgaard

Looking to Shake Off Poor Major Showing at TPC Craig Ranch
Joel Dahmen

is of No DFS Consideration This Week in Dallas
Pierceson Coody

is Not The Fun DFS Play He Used to Be
Tank Bigsby

Is Tank Bigsby a Worthy Dynasty Stash Entering 2026?
Hunter Henry

Profiles as a Dynasty Sell-High Candidate Entering 2026
Gerrit Cole

to Make Season Debut on Friday Against Rays
Matthew Golden

Can Matthew Golden Re-Establish His Dynasty Value in 2026?
Jalen Coker

a Prime Buy-Low Dynasty Target
Dak Prescott

Remains a High-Floor Dynasty Quarterback
CeeDee Lamb

Is CeeDee Lamb's Dynasty Value Poised to Rise in 2026?
Keon Coleman

Joe Brady Likes What he's Seen From Keon Coleman
Deshaun Watson

Hitting it Off With Todd Monken?
Jacoby Brissett

Not Present for First OTA Practice
Tua Tagovailoa

Michael Penix Jr. Splitting First-Team Reps at OTAs
Rashee Rice

Tests Positive for Marijuana, Violating his Probation
Cam Skattebo

Says he'll be Ready for Week 1
De'Von Achane

Present for Start of OTAs This Week
Malik Washington

an Affordable Trade Target in Dynasty Leagues
Patrick Mahomes

Is Patrick Mahomes Still a Top-Five Dynasty Quarterback?
Michael Trigg

Is There a Spot for Michael Trigg in Dallas?
Seth McGowan

in the Mix for Playing Time as a Rookie?
Audric Estimé

Audric Estime Droppable in Dynasty Leagues?
Drake Baldwin

Braves Place Drake Baldwin on Injured List With Oblique Strain
Kyren Williams

Have Timeshare Concerns Sunk Kyren Williams' Dynasty Value Too Low?
Ja'Marr Chase

Is Ja'Marr Chase the Most Valuable Player in Dynasty?
Javonte Williams

' Unusual Career Path Has Left Him Undervalued in Dynasty Leagues
CFB

Ezavier Crowell has Immediate Opportunity at Alabama
CFB

Mark Bowman a Day 1 Impact Player for USC?
CFB

Bill Belichick Says Relationship with First North Carolina Team "Wasn't Great"
Alex Caruso

Erupts for 31 Points in Game 1 Loss to Spurs
CFB

Kemario Taylor a Breakout Candidate at Quarterback
Jalen Williams

Productive in Comeback Game
CFB

Trinidad Chambliss the Undisputed Top SEC Quarterback Entering 2026?
Shai Gilgeous-Alexander

Records First Double-Double of Postseason
CFB

Rocco Becht The "Unifier" of Penn State's Roster
Stephon Castle

Opens Conference Finals With Double-Double
Dylan Harper

Makes Outstanding Two-Way Impact in Game 1 Win
Victor Wembanyama

Dominates Game 1 Against Thunder
Mattias Samuelsson

Picks Up an Assist in Season-Ending Loss
Rasmus Dahlin

Nets Fourth Postseason Goal
Jakub Dobes

Records 37 Saves in Game 7 Win
Lane Hutson

Contributes Power-Play Assist in Game 7 Victory
Nick Suzuki

Extends Road Point Streak
Alex Newhook

Scores Series-Clincher in Overtime
Jackson Holliday

Orioles Reinstate Jackson Holliday From Injured List on Monday
Ronald Acuña Jr.

Braves Reinstate Ronald Acuna Jr. From Injured List on Monday
Jose Altuve

Astros Put Jose Altuve on Injured List With Oblique Strain
Larry Nance Jr.

is Questionable for Game 1 on Tuesday
OG Anunoby

is Probable for Tuesday's Game 1
Luke Kornet

is Cleared for Game 1
New Orleans Pelicans

Jamahl Mosley Agrees to Become Pelicans Next Head Coach
De'Aaron Fox

is Ruled Out for Game 1 on Monday
Ukko-Pekka Luukkonen

Set to Start Game 7
Corey Seager

Going on Injured List With Back Injury
Tage Thompson

Can Match Franchise Record With Another Multi-Point Game
Nick Suzuki

Seeks More Road Success Monday
Lane Hutson

Riding a Five-Game Assist Streak Into Game 7
Filip Gustavsson

Needs Offseason Surgery
Jeremy Peña

Jeremy Pena Reinstated and Starting on Monday Against Twins
Melquizael Costa

Drops Decision At UFC Vegas 117
Arnold Allen

Bounces Back
Daniel Santos

Suffers Second-Round TKO Loss
MMA

Dohoo Choi Wins His Third Consecutive Fight
Malcolm Wellmaker

Suffers His Second Loss In A Row
Juan Diaz

Scores Second-Round Submission
Christian Edwards

Defeated At UFC Vegas 117
CFB

Transfer Running Back Arnold Barnes Visiting Iowa State on Monday
Modestas Bukauskas

Gets Split-Decision Win
Jhostynxon Garcia

Expected to Join the Pirates on Tuesday
Tobias Harris

Goes Cold in Game 7 Loss
Quinn Hughes

Open to Signing Extension This Offseason
Jalen Duren

Finishes Game 7 with Quiet Line
Cade Cunningham

Endures Cold Shooting Night Sunday
Joel Eriksson Ek

Misses Second Round Due to Heel Injury
Sam Merrill

Catches Fire in Game 7 Win
Evan Mobley

Posts Versatile Double-Double in Game 7
Jonas Brodin

Sits Out Round 2 Due to Toe Injury
Sam Malinski

Practices Fully Sunday
Josh Manson

Rejoins Practice
Colt Emerson

Mariners Promoting Top Prospect Colt Emerson to Major Leagues
Munetaka Murakami

Fantastic First Season Continues With Two More Homers
Cristopher Sánchez

Cristopher Sanchez Dazzles With 13-Strikeout Complete Game on Saturday
Blake Snell

to Undergo Elbow Surgery on Tuesday
Clay Holmes

Could Miss Around Three Months
Jose Altuve

Exits After Swing
Corey Seager

Absent With Back Spasms on Saturday
Jeremy Lauzon

Misses Saturday's Practice
Mark Stone

Doesn't Practice Saturday
Josh Manson

Misses Practice, Considered Day-to-Day
Brent Burns

Day-to-Day Ahead of Conference Finals
Cale Makar

Considered Day-to-Day
Trevor Story

Hits the Injured List With Groin Injury
Blake Snell

Likely to Need Elbow Surgery
Kyle Schwarber

on a Heater, Hits Two More Homers to Take Major-League Lead
Clay Holmes

Suffers Fractured Fibula on Friday Night
Blake Snell

Heads to 15-Day Injured List
Blake Snell

Scratched From Start on Friday for Undisclosed Reasons
CFB

Julian Sayin Looking To Build Off Of Strong Debut Season
CFB

College GameDay Set for First Three Weeks
CFB

Jeremiah Smith Aiming For Ohio State Receiving Records
CFB

Keshaun Singleton Projects as Auburn's WR1
CFB

Jeremiah Cobb Impresses New Auburn Staff
CFB

Alberto Mendoza Very Likely to Start for Georgia Tech
CFB

Charles Woodson Jr. Commits to Michigan
Melquizael Costa

Set For UFC Vegas 117 Main Event
Arnold Allen

A Favorite At UFC Vegas 117
Daniel Santos

Set For UFC Vegas 117 Co-Main Event
MMA

Dohoo Choi Returns At UFC Vegas 117
Juan Diaz

Set To Make His UFC Debut
Malcolm Wellmaker

Looks To Bounce Back
Christian Edwards

Set For His UFC Debut
Modestas Bukauskas

Looks To Get Back In The Win Column
CFB

Virginia Tech Lands Commitment from Four-Star QB Peter Bourque
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF