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DraftKings Daily Fantasy Baseball Picks (5/22/18): MLB DFS Lineups

We have a monster 15-game slate to break down today, and there are some great options across the board. There are a few high-priced pitchers on the slate you should be looking to pay up for, along with plenty of bats you want to jam into your lineups.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 5/22/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @DFS_Tom.

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DraftKings Starting Pitchers

Chris Sale - P, BOS @ TB (DK - $13,100)

Chris Sale is the most expensive pitcher on the slate, and I give him the edge over Cole for a few reasons, so let's take a look. Sale has pitched seven or more innings in three of his last four starts, compared to Cole's one game at seven or more innings in his last four starts. That might not seem like a big deal, but when you are paying up for a pitcher in this price range, you want to know they are going deep into the game, and not get pulled early. Sale is up against the Rays, who have a 23.5% strikeout rate vs left-handed pitcher this season, which is 11th worst in the league. This is a nice positive park shift in Sale's favor, as he is in Tampa and away from Fenway Park. Sale has racked up nine or more strikeouts in three of his last four starts, including two games with 12 or more.

Caleb Smith - P, MIA @ NYM (DK - $6,400)

Smith is a cheaper option at pitcher, who has a few factors going in his favor tonight. First off, he is up against the Mets, who have a 26.7% strikeout rate vs left-handed pitchers, which is third worst in the league. The first time Smith faced the Mets this season, he put up seven strikeouts in five innings, while allowing three earned runs. If he is able to limit the earned runs and squeeze out one more inning, we could be looking at some serious value for a pitcher who is under $7K. Great park factor in his favor should allow him to limit the damage.

 

DraftKings Infielders

Josh Bell - 1B, PIT @ CIN (DK - $4,100)

Bell and the Pirates will be in Cincinnati to face Matt Harvey, who will be making his first start at home for the Reds. This is one of the best hitter's parks in the league, and with how bad Harvey is, this likely won't end well. Bell comes in with a .314 wOBA and a .138 ISO vs right-handed pitchers this season, which is good, but not great, so use him in a stack compared to solo.

Jed Lowrie - 2B, OAK vs SEA (DK - $4,200)

Lowrie comes into this game with a .424 wOBA and a .273 ISO vs right-handed pitchers this season, which are truly great numbers for a second baseman. He is up against Mike Leake, who is giving up a .363 wOBA to lefties, along with 1.01 HR/9 this season. Some good numbers to pick on and Oakland can make a sneakier stack tonight.

Travis Shaw - 3B, MIL vs ARI (DK - $4,500)

Shaw is an absolute monster when facing right-handed pitchers this season, specifically at home this season as he has a .421 wOBA and a .326 ISO. Those are some massive numbers and we could easily be looking at a home run tonight, as he has one last night, and the last time he faced Matt Koch, back on the 16th of this month. Lot of things lining up for him tonight and really like a Brewers stack in GPPs.

Miguel Rojas - SS, MIA @ NYM (DK - $3,100)

Rojas offers a bit of salary relief on this slate and despite his lower price, he has some solid numbers as well. This season he has a .326 wOBA and a .160 ISO vs right-handed pitchers, which are solid numbers for a player on one of the weaker teams in the league. He has two home runs in his last 10 games and had one home run when he faced Zack Wheeler earlier this season #BvP.

 

DraftKings Outfielders

Mookie Betts - OF, BOS @ TB (DK - $6,000)

Betts is the most expensive hitter on the entire slate, but yeah...he is crushing it right now. Over his last 10 games, he has two home runs, six doubles, five RBIs, and 17 total hits. With that kind of production, you should be looking to get him into your lineups really anytime he is on the slate. Now his production will cool down at some point, but if he is this hot, you don't want to pass him up.

Leonys Martin - OF, DET @ MIN (DK - $3,800)

Martin is back from his injury, and even though he is cold right now, he has a good opportunity to bounce back. He comes into this game with a .384 wOBA vs right-handed pitchers and has hit four of his five home runs against them this season. He is up against Lance Lynn, who is giving up a horrendous, .446 wOBA to lefties this season, along with 2.09 HR/9.

 

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

Jacory Croskey-Merritt

Held Out of OTAs on Wednesday
Jayden Daniels

Participating in Commanders OTAs
Chris Bell

No Timetable for Chris Bell's Return from Knee Surgery
De'Von Achane

Limited in OTAs Due to Recovery From Shoulder Injury
MarShawn Lloyd

Participating in Packers OTAs
Josh Jacobs

No Criminal Charges Filed Against Josh Jacobs
Eury Pérez

Eury Perez Pulled Early on Wednesday With Hamstring Issue
Daniel Jones

Present at OTA Practice on Wednesday
CFB

Drew Mestemaker a Top Big 12 Quarterback Right Away?
T.J. Hockenson

Dynasty Stock Continues to Trend Down
Jordan Addison

Is Jordan Addison a Clear Buy-Low Candidate Ahead of 2026?
Cade Otton

Continues to Offer Depth in Dynasty Leagues
PGA

Sungjae Im Remains Boom-or-Bust at Colonial
Jared Goff

Continues to Have Dynasty Appeal at 31 Years Old
Tez Johnson

No Clear Path to Fantasy Relevance for Tez Johnson in Tampa Bay?
PGA

Michael Thorbjornsen Trending in Wrong Direction Entering Colonial
Zach Ertz

Could Still Contribute in Dynasty Leagues
De'Aaron Fox

Limited to Nine Points in Game 5 Loss
Russell Henley

a Top Option at Colonial
Dyami Brown

Holds Little Dynasty Value in His Return to Washington
Harry Hall

Hoping Putter Carries Him at Colonial
Julian Champagnie

Notches 22 Points With Four Triples Tuesday
Trevor Etienne

Could Still Find Dynasty Relevance After Quiet Rookie Season
Stephon Castle

Leads Spurs in Scoring Tuesday Night
Rickie Fowler

Looks to Regain Momentum at Colonial
Victor Wembanyama

Struggles in Game 5 Loss to Thunder
Bam Knight

Dynasty Value Has Run Dry in Crowded Running Back Room
Alex Caruso

a Difference-Maker Again in Game 5
Pierceson Coody

Looking to Stay Hot at Colonial
Jared McCain

Produces 20 Points in First Playoff Start
Mac Jones

and 49ers Agree to a Revised Contract
Shai Gilgeous-Alexander

Scores Game-High 32 Points in Game 5 Win
Martin Necas

Collects an Assist in Game 4 Loss to Golden Knights
Gabriel Landeskog

Scores Only Avalanche Goal in Season-Ending Loss
Carter Hart

Finishes Series-Clincher With 20 Saves
Dylan Coghlan

Continues Unlikely Success Story
Cole Smith

Scores Series-Clincher Tuesday Night
Mark Stone

Nets Another Goal as Golden Knights Finish Off Avalanche
Ludvig Aberg

Looking to Exchange Momentum for a Victory in Fort Worth
Stephan Jaeger

Trending Upward as PGA Heads to Fort Worth
Max Homa

Comes Off Awful Putting Performance at PGA Championship
Tony Finau

Faces Different Test at the Colonial
Robert MacIntyre

Seeks Better Beginning in Fort Worth
Tom Hoge

Ups and Downs Could Continue at Colonial
Brian Harman

Not Having the Best Golf Season in 2026
Austin Eckroat

Struggling Too Often Heading to Charles Schwab Challenge
Zach Bauchou

Tries to Keep Momentum Rolling at Colonial
Keegan Bradley

Looking to Rebound at Colonial
Tory Horton

Could Do Some Stuff "Toward the End of Spring"
Patrick Mahomes

Takes Part in First OTA Practice on Tuesday
Los Angeles Chargers

Derwin James Jr. Becomes Highest-Paid Safety for the Second Time in his Career
Chris Brooks

Emerging as Top Handcuff to Stash?
Jared McCain

Moves into Starting Five
Boston Celtics

Joe Mazzulla Wins Coach of the Year
Jalen Williams

is Ruled Out for Game 5 on Tuesday
Zion Williamson

to See More Versatile Role
Cleveland Cavaliers

Kenny Atkinson to Remain Cavaliers Head Coach Next Season
Claude Giroux

Planning to Return for 20th NHL Campaign
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Mackenzie Blackwood

in Net for Game 4 Against Golden Knights
Valeri Nichushkin

a Game-Time Call Tuesday
Nathan MacKinnon

Will Suit Up Tuesday
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
Justin Thomas

Trending Well Ahead of Charles Schwab Challenge
Akshay Bhatia

Lacking Driving Prowess Needed at Colonial Country Club
CFB

DJ Lagway Looking to Rebound at Baylor
CFB

Josh Hoover Tasked With Leading Indiana Back to the Playoffs
CFB

Braylon Staley the Next 1,000-Yard Tennessee Receiver?
CFB

Ahmad Hardy's Return Timeline Remains Unclear
Evan Mobley

Finishes Season-Ending Loss With 15 Points
James Harden

Wants to Stay in Cleveland
Donovan Mitchell

Remains Committed to Cavaliers
Mikal Bridges

Cools Off in Game 4 Against Cavaliers
OG Anunoby

Active on Both Ends in Blowout Win
Karl-Anthony Towns

Leads Knicks in Scoring During Series-Clincher
Jalen Brunson

Named Eastern Conference Finals MVP
Ivan Demidov

Contributes an Assist in Losing Effort
Lane Hutson

Records Power-Play Goal in Game 3 Loss
Frederik Andersen

Enjoys Another Easy Night at the Office in Game 3
Shayne Gostisbehere

Scores First Postseason Goal
Taylor Hall

Ends Four-Game Goal Drought
Andrei Svechnikov

Scores Game 3 Winner in Overtime
Gage Jump

Athletics to Promote Top Pitching Prospect Gage Jump to Major Leagues
Tatsuya Imai

Two Relievers Combine to No-Hit the Rangers on Monday
Dennis Schröder

Dennis Schroder is Ruled Out for Game 4 on Monday
Michael Porter Jr.

Nets Could Trade Michael Porter Jr.
Valeri Nichushkin

Nathan MacKinnon, Valeri Nichushkin Uncertain for Game 4
Oliver Kapanen

Sitting as Healthy Scratch Monday
Max Domi

Out Indefinitely Due to Offseason Surgery Complications
Dylan Cease

Heading to Injured List With Hamstring Injury
Daniel Suarez

Wins at Charlotte in Rain-Shortened Coca-Cola 600
Christopher Bell

Finishes as the Runner-Up in the Coca-Cola 600 at Charlotte
Denny Hamlin

Falls Short of Winning and Places Third at Charlotte
Tyler Reddick

Places Fourth After Leading Laps at Charlotte
Kyle Larson

Strong and Consistent Day Ends in Fifth at Charlotte
Dylan Cease

Removed From Sunday's Start With Hamstring Discomfort
Vladimir Guerrero Jr.

Exits Sunday's Game Early with Elbow Contusion
MLB

Reds-Cardinals Game Postponed on Sunday
Edward Cabrera

Cubs Place Edward Cabrera on the 15-Day Injured List
Denny Hamlin

the Favorite to Win at Charlotte
Tyler Reddick

on Pole for Coca-Cola 600
Christopher Bell

Could Break Out of Slump
Kyle Larson

May have A Solid Day at Charlotte
Ryan Blaney

Is A DFS Risk for Charlotte Lineups
William Byron

Could have A Great DFS Performance at Charlotte
Chase Briscoe

Is A Solid Tournament Option for Charlotte DFS Lineups
Ty Gibbs

May not be Worth his Salary for Charlotte DFS Lineups
Chris Buescher

May be a Sneaky Tournament Option for Charlotte Lineups
NASCAR

Bubba Wallace Has Favorable Upside for Charlotte DFS Lineups
Ross Chastain

Is A Strong Addition for DFS Lineups at Charlotte
Austin Dillon

Should Fantasy Managers Roster Austin Dillon for Charlotte DFS Lineups?
Chase Elliott

Should Be Strong at Charlotte
Carson Hocevar

Confident for Coca-Cola 600
Corey Heim

a Chalk DFS Pick at Charlotte
Michael McDowell

Is Michael McDowell A Tournament Option for Charlotte Lineups?
MLB

Orioles-Tigers Game Postponed on Saturday
MLB

Rays-Yankees Postponed on Saturday
Mickey Moniak

Heads to Injured List With Ankle Sprain
Jackson Merrill

has Sore Ribs, Expected to Avoid Injured List
CFB

Jaron-Keawe Sagapolutele Looking to Take Sophomore Leap
CFB

Jadan Baugh Primed to Lead Florida Offense in 2026
CFB

LSU Hires Ed Orgeron As Special Assistant
CFB

North Carolina and South Carolina Cancel Home-And-Home Series
CFB

Confidence High in Mississippi State's Kamario Taylor
MLB

Reds-Cardinals Game Postponed on Friday
Trevor Story

has Hernia Surgery, Expected to Miss 6-10 Weeks
Roman Anthony

Dealing With Sprained Ligament in his Finger
Ronald Acuña Jr.

Ronald Acuna Jr. Exits Early, X-Rays Come Back Negative
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF