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DraftKings Daily Fantasy Baseball Picks (5/22/18): MLB DFS Lineups

We have a monster 15-game slate to break down today, and there are some great options across the board. There are a few high-priced pitchers on the slate you should be looking to pay up for, along with plenty of bats you want to jam into your lineups.

In this article, I will be providing you with my daily fantasy baseball lineup picks for DraftKings on 5/22/18. The lineup picks will range from some of the elite players to mid-priced options and value plays.

You can also read more DFS advice and lineup picks for sites like FanDuel, and other sports too. If you have any questions or comments, feel free to hit me up on Twitter @DFS_Tom.

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DraftKings Starting Pitchers

Chris Sale - P, BOS @ TB (DK - $13,100)

Chris Sale is the most expensive pitcher on the slate, and I give him the edge over Cole for a few reasons, so let's take a look. Sale has pitched seven or more innings in three of his last four starts, compared to Cole's one game at seven or more innings in his last four starts. That might not seem like a big deal, but when you are paying up for a pitcher in this price range, you want to know they are going deep into the game, and not get pulled early. Sale is up against the Rays, who have a 23.5% strikeout rate vs left-handed pitcher this season, which is 11th worst in the league. This is a nice positive park shift in Sale's favor, as he is in Tampa and away from Fenway Park. Sale has racked up nine or more strikeouts in three of his last four starts, including two games with 12 or more.

Caleb Smith - P, MIA @ NYM (DK - $6,400)

Smith is a cheaper option at pitcher, who has a few factors going in his favor tonight. First off, he is up against the Mets, who have a 26.7% strikeout rate vs left-handed pitchers, which is third worst in the league. The first time Smith faced the Mets this season, he put up seven strikeouts in five innings, while allowing three earned runs. If he is able to limit the earned runs and squeeze out one more inning, we could be looking at some serious value for a pitcher who is under $7K. Great park factor in his favor should allow him to limit the damage.

 

DraftKings Infielders

Josh Bell - 1B, PIT @ CIN (DK - $4,100)

Bell and the Pirates will be in Cincinnati to face Matt Harvey, who will be making his first start at home for the Reds. This is one of the best hitter's parks in the league, and with how bad Harvey is, this likely won't end well. Bell comes in with a .314 wOBA and a .138 ISO vs right-handed pitchers this season, which is good, but not great, so use him in a stack compared to solo.

Jed Lowrie - 2B, OAK vs SEA (DK - $4,200)

Lowrie comes into this game with a .424 wOBA and a .273 ISO vs right-handed pitchers this season, which are truly great numbers for a second baseman. He is up against Mike Leake, who is giving up a .363 wOBA to lefties, along with 1.01 HR/9 this season. Some good numbers to pick on and Oakland can make a sneakier stack tonight.

Travis Shaw - 3B, MIL vs ARI (DK - $4,500)

Shaw is an absolute monster when facing right-handed pitchers this season, specifically at home this season as he has a .421 wOBA and a .326 ISO. Those are some massive numbers and we could easily be looking at a home run tonight, as he has one last night, and the last time he faced Matt Koch, back on the 16th of this month. Lot of things lining up for him tonight and really like a Brewers stack in GPPs.

Miguel Rojas - SS, MIA @ NYM (DK - $3,100)

Rojas offers a bit of salary relief on this slate and despite his lower price, he has some solid numbers as well. This season he has a .326 wOBA and a .160 ISO vs right-handed pitchers, which are solid numbers for a player on one of the weaker teams in the league. He has two home runs in his last 10 games and had one home run when he faced Zack Wheeler earlier this season #BvP.

 

DraftKings Outfielders

Mookie Betts - OF, BOS @ TB (DK - $6,000)

Betts is the most expensive hitter on the entire slate, but yeah...he is crushing it right now. Over his last 10 games, he has two home runs, six doubles, five RBIs, and 17 total hits. With that kind of production, you should be looking to get him into your lineups really anytime he is on the slate. Now his production will cool down at some point, but if he is this hot, you don't want to pass him up.

Leonys Martin - OF, DET @ MIN (DK - $3,800)

Martin is back from his injury, and even though he is cold right now, he has a good opportunity to bounce back. He comes into this game with a .384 wOBA vs right-handed pitchers and has hit four of his five home runs against them this season. He is up against Lance Lynn, who is giving up a horrendous, .446 wOBA to lefties this season, along with 2.09 HR/9.

 

MLB DFS News and Injury Alerts




REAL-TIME FANTASY NEWS

Deiveson Figueiredo

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Gets Second-Round Submission Win
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Taking a Job with CBS for 2026 Season
JuJu Smith-Schuster

Giants Adding JuJu Smith-Schuster on a One-Year Deal
Zhang Mingyang

Suffers Back-To-Back Losses
Alonzo Menifield

Gets Back In The Win Column
Braxton Berrios

New York Giants Agree to One-Year Deal with Braxton Berrios
Odell Beckham Jr.

Signing with Giants
Tallison Teixeira

Suffers First-Round Knockout Loss
Myles Garrett

and Jared Verse Swap Teams in Blockbuster Deal
Sergei Pavlovich

Scores First-Round Knockout Win
Cameron Smotherman

Suffers Third Loss In A Row
Edwin Arroyo

Reds Promote Top Infield Prospect Edwin Arroyo, Viewed as Priority Pick Up Ahead of MLB Debut
Kai Asakura

Earns His First UFC Win
Elly De La Cruz

Placed on IL with Right Hamstring Tightness
Mason Taylor

Dynasty Value Takes a Hit for Now
Denny Hamlin

Earns the first Nashville Cup Series Victory of his Career on Sunday
Zachariah Branch

a Steal in the Second Round of Rookie Drafts?
Christopher Bell

Finishes as the Runner-Up at Nashville
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Earns First Career Podium Finish at Nashville
Ryan Blaney

Scores A Solid Top-10 Finish at Nashville
Eli Stowers

Worth Targeting Now Before Eventual Breakout?
Kyle Larson

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Germie Bernard

Expected to Require Some Patience in Dynasty Leagues
Denzel Boston

a First-Round Target in Dynasty Rookie Drafts
Bryce Young

Dynasty Value Impacted by Inconsistency
Jeremiyah Love

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Odell Beckham Jr.

Giants Working Out JuJu Smith-Schuster and Braxton Berrios in Addition to Odell Beckham Jr.
Odell Beckham Jr.

Working Out for Giants
A.J. Brown

Could Be Dealt Within Next 24 Hours
Parker Washington

Set to Play "Most Important Role" of His Career in Jaguars Offense
Elly De La Cruz

Exits with Hamstring Tightness
Tyler Reddick

Is One of the Top Favorites to Win at Nashville
Kyle Larson

May Continue his Top-10 Consistency at Nashville this week
Christopher Bell

Is One of the Top Competitors for the Win at Nashville
Chase Briscoe

Is A Must Start for Nashville DFS Lineups
Chase Elliott

has Plenty of Upside for Nashville DFS Lineups
William Byron

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Wan'Dale Robinson

Dynasty Value May Have Peaked in 2025
Carson Hocevar

Is Likely to have Another Solid Result at Nashville
Tyler Shough

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NASCAR

Should Fantasy Players Roster Bubba Wallace at Nashville?
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Dynasty Upside Remains High Despite Questionable Offensive Environment in New York
Chris Buescher

Is A Decent All-Around DFS Option for Nashville Lineups
Daniel Suarez

is Likely to Drop Positions during the Cracker Barrel 400
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Carries Dynasty Sell-High Appeal After Breakout 2025 Campaign
Emeka Egbuka

Undervalued in Dynasty Formats After Underwhelming Close to 2025?
Garrett Crochet

Suffers Setback, Likely to Undergo MRI for Lat Tightness
Denny Hamlin

Could Denny Hamlin Dominate at Nashville?
Ryan Blaney

Is a DFS Tournament Option at Nashville
Ty Gibbs

Don't Overlook Ty Gibbs at Nashville
Joey Logano

Could Show Life at Nashville
Ross Chastain

Needs a Good Run at Nashville
Chet Holmgren

Fails to Step Up in the Season Finale
Cason Wallace

Ends Postseason with Strong Showing
Shai Gilgeous-Alexander

Caps MVP Season with Game 7 Exit
Stephon Castle

Continues Postseason Run with 16 Points
Julian Champagnie

Shines in Series-Clinching Win
De'Aaron Fox

Provides Secondary Punch in Game 7 Triumph
Victor Wembanyama

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Warriors Prioritize Depth Around Returning Steve Kerr
Donovan Mitchell

Remains Cleveland's Top Priority
Adou Thiero

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76ers Hire Mike Gansey as President of Basketball Operations
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Chicago Bulls Explore Kevin Young as Coaching Candidate
Kyrie Irving

Reports He's Nearing Full Strength in ACL Recovery
Lane Hutson

Posts a Power-Play Assist in Game 5 Loss
Cole Caufield

Nets a Power-Play Goal in Season-Ending Loss
Seth Jarvis

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Logan Stankoven

Notches Three Points in Big Game 5 Win
Taylor Hall

Racks Up Three Points in Series-Clinching Win
Frederik Andersen

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Jacob Gonzalez

is Heading to the Big Leagues
Munetaka Murakami

Exits with Hamstring Tightness
Mitchell Robinson

Plans to Play in Game 1 After Finger Surgery
Ajay Mitchell

Ruled Out for Game 7
Jalen Williams

Unavailable in Decisive Game 7
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Magic Finalizing Hire of Sean Sweeney as Head Coach
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Eury Perez is Placed on 15-Day Injured List
Deiveson Figueiredo

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Yadong Song Returns At UFC Macau
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Sergei Pavlovich

A Favorite At UFC Macau
Cameron Smotherman

Looks To Bounce Back
Kai Asakura

Looks To Get Back In The Win Column
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Faizon Brandon In Position to Start Week 1
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Dane Weber Commits to Cal
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Joey McGuire Attempts to Add Texas to Schedule
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Mike Leach on 2027 College Football Hall of Fame Ballot
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Maryland, Baylor Schedule Home-and-Home
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Taron Dickens Decommits From North Carolina
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Limited in Game 6 Return
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Provides Bench Spark in Game 6 Loss
Shai Gilgeous-Alexander

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De'Aaron Fox

Struggles From the Field Thursday
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MLB Proposes Hard Salary Cap as Part of Next CBA
Kenley Jansen

Tigers Place Kenley Jansen on Injured List With Pelvic Inflammation
Teoscar Hernández

Teoscar Hernandez Heading to Injured List With Hamstring Strain
MON

Lane Hutson Struggles in Game 4 Loss
CAR

Logan Stankoven Nets Eighth Postseason Goal
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Sebastian Aho Pots Game-Winner on Power Play
CAR

Nikolaj Ehlers Tallies Two Helpers in Impressive Road Win
CAR

Shayne Gostisbehere Records Two Assists in Game 4 Win
CAR

Frederik Andersen Establishes Hurricanes New Postseason Shutout Record
Yordan Alvarez

Continues Homer Barrage With Two More Long Balls on Wednesday
Cristopher Sánchez

Cristopher Sanchez Makes History With Seven More Shutout Innings Against Padres
Teoscar Hernández

Teoscar Hernandez Lifted From Wednesday's Game Early With Hamstring Strain
Kenley Jansen

Exits Relief Appearance on Wednesday With Groin Injury
Eury Pérez

Eury Perez Pulled Early on Wednesday With Hamstring Issue
CFB

Drew Mestemaker a Top Big 12 Quarterback Right Away?
PGA

Sungjae Im Remains Boom-or-Bust at Colonial
PGA

Michael Thorbjornsen Trending in Wrong Direction Entering Colonial
Russell Henley

a Top Option at Colonial
Harry Hall

Hoping Putter Carries Him at Colonial
Rickie Fowler

Looks to Regain Momentum at Colonial
Pierceson Coody

Looking to Stay Hot at Colonial
Martin Necas

Collects an Assist in Game 4 Loss to Golden Knights
Gabriel Landeskog

Scores Only Avalanche Goal in Season-Ending Loss
Carter Hart

Finishes Series-Clincher With 20 Saves
Dylan Coghlan

Continues Unlikely Success Story
Cole Smith

Scores Series-Clincher Tuesday Night
Mark Stone

Nets Another Goal as Golden Knights Finish Off Avalanche
Ludvig Aberg

Looking to Exchange Momentum for a Victory in Fort Worth
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Trending Upward as PGA Heads to Fort Worth
Max Homa

Comes Off Awful Putting Performance at PGA Championship
Tony Finau

Faces Different Test at the Colonial
Robert MacIntyre

Seeks Better Beginning in Fort Worth
Tom Hoge

Ups and Downs Could Continue at Colonial
Brian Harman

Not Having the Best Golf Season in 2026
Austin Eckroat

Struggling Too Often Heading to Charles Schwab Challenge
Zach Bauchou

Tries to Keep Momentum Rolling at Colonial
Keegan Bradley

Looking to Rebound at Colonial
Claude Giroux

Planning to Return for 20th NHL Campaign
Carter Hart

Aiming for Sixth Consecutive Win Tuesday
Evgeni Malkin

Inks New One-Year Deal With Penguins
Ben Griffin

Looking to Repeat This Week at Colonial
Rasmus Hojgaard

a Player to Avoid at Charles Schwab Challenge
Hideki Matsuyama

Needs Solid Driving Week at Charles Schwab Challenge
RANKINGS
C
1B
2B
3B
SS
OF
SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF