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The San Francisco 49ers have officially ruled out quarterback Brock Purdy (toe) for Week 2 action against the New Orleans Saints, according to NBC Sports' Matt Maiocco. Purdy is dealing with turf toe despite playing the entirety of the Week 1 win over the Seattle Seahawks last weekend. Not only will the 25-year-old miss this Sunday's game, but reports this week have suggested that he could be out multiple weeks. It's more bad news for an extremely battered Niners team early in 2025. Tight end George Kittle (hamstring) is also out this weekend and will miss at least four games after being placed on Injured Reserve. Former New England Patriots QB Mac Jones will run San Fran's offense against the Saints. Expect plenty of short and intermediate throws while they lean heavily on running back Christian McCaffrey. At best, Jones is a desperation QB2 in superflex fantasy leagues.--Keith Hernandez
Source: NBC Sports Bay Area - Matt Maiocco
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REAL-TIME FANTASY NEWS

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Looks To Extend His Win Streak
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