Who Should I Start for Fantasy Football Week 16? Jameson Williams, Marvin Harrison Jr., Chuba Hubbard, Drake London, Jayden Higgins, Christian Watson, Javonte Williams, Aaron Jones Sr., Ricky Pearsall, Tyler Allgeier

Jameson Williams, WR, Detroit Lions

Across seven games before his team's Week 8 bye, Detroit Lions wide receiver Jameson Williams had recorded just 17 receptions and looked like he was headed towards a disappointing year. However, the 24-year-old has had a breakout second half of the 2025 season and is now up to 52 receptions for 936 yards and seven touchdowns on 81 targets across 14 games. Over his last three games in particular, Williams has been dominant, hauling in 21 catches for 374 yards and two touchdowns on 28 targets.

With Lions tight end Sam LaPorta (back) on Injured Reserve, Williams has emerged as the clear number two option in the Detroit passing game. With their defense struggling, the Lions have also been forced into more pass-heavy game scripts, leading quarterback Jared Goff to average 36 pass attempts per game over the last five contests. Between LaPorta's injury and Detroit's tendency to find itself in shootouts, Williams should see plenty more opportunities for production heading into matchups against the Pittsburgh Steelers and Minnesota Vikings over the next two weeks.

Marvin Harrison Jr., WR, Arizona Cardinals

Arizona Cardinals wide receiver Marvin Harrison Jr. (heel) has "looked pretty good" in his return to practice this week, according to head coach Jonathan Gannon. "Getting his wind back a little bit. That's a tough injury, but particularly (for) a skill guy that runs fast and has to decelerate and accelerate. Our staff has done a good job with him. He's done a good job pushing through. We'll see how he does today," Gannon said.

The head coach added that the team "will have a plan for him" when asked about any extra concern about getting his conditioning back for a return this Sunday against the Atlanta Falcons. After missing the last two weeks with a heel injury and four of the last five weeks due to an appendectomy, Harrison looks primed to return in Week 16. However, he could take a back seat to Michael Wilson, who has gone nuclear for fantasy managers in Harrison's absence. If Harrison is active, treat him as a low-end WR2 in fantasy football.

Jayden Higgins, WR, Houston Texans

Houston Texans rookie wide receiver Jayden Higgins was held to just one target for the fifth time this season in Sunday's 40-20 blowout win over the visiting Arizona Cardinals. He caught one pass for a gain of four yards. The 23-year-old has four receptions on six targets for just 38 yards and no touchdowns in the last two games. The last time that Higgins had only one target came on Nov. 2 against the Denver Broncos.

Higgins had a streak of five games with at least five targets from Weeks 9 to 14 before seeing just one look from quarterback C.J. Stroud on Sunday. The second-rounder from Iowa State ranks third on the team with 397 receiving yards in 14 games this year, adding four touchdowns. While Higgins has been quiet the last two games, he's a good bet to bounce back with a strong game for fantasy managers in deeper leagues as a flex play in an excellent Week 16 matchup against the last-place Raiders. Higgins is rostered in 43% of Yahoo leagues, so he's widely available.

Christian Watson, WR, Green Bay Packers

Green Bay Packers wide receiver Christian Watson (chest, shoulder) is officially questionable to play in Week 16 versus the division-rival Chicago Bears in the Windy City on Saturday night, according to Adam Schefter of ESPN. Watson injured his chest/shoulder on a hard fall in Sunday's loss to the Denver Broncos and was sent to the hospital as a precaution. The 26-year-old was cleared of a major injury and said he was "feeling pretty good" this week, but his status for Week 16 will come down to a medical decision on Saturday.

Fantasy managers will need to check back on Saturday for Green Bay's inactives before putting Watson into starting lineups for the week. He has been quarterback Jordan Love's go-to receiver in his eight games played, catching 28 passes for 481 yards and five touchdowns. If Watson isn't cleared, Jayden Reed, Romeo Doubs, and rookie Matthew Golden would all have higher ceilings in Chicago.