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Who Should I Start for Fantasy Football Week 16? Derrick Henry, Jacory Croskey-Merritt, Jonathan Taylor, Josh Jacobs, Chase Brown, Isiah Pacheco, De'Von Achane, Saquon Barkley, Nick Chubb

Jacory Croskey-Merritt - Fantasy Football Rankings, Draft Sleepers, NFL DFS Picks

Who Should I Start for Week 16? Fantasy Football outlooks for Derrick Henry, Jacory Croskey-Merritt, Jonathan Taylor, Josh Jacobs, Chase Brown, Isiah Pacheco, De'Von Achane, Saquon Barkley, Nick Chubb.

Who Should I Start? Who Should I Sit? Some of the most common Week 16 fantasy football lineup decisions involve players like Derrick Henry, Jacory Croskey-Merritt, Jonathan Taylor, Josh Jacobs, Chase Brown, Isiah Pacheco, De'Von Achane, Saquon Barkley, Nick Chubb. However, don't worry, we are here to help you make these decisions and build winning lineups in Week 16. Set your optimal fantasy football lineups for Week 16 of the 2025 NFL season. Our free Who Should I Start? tool will help make your fantasy football lineup decisions. Compare up to four NFL players, and we tell you who to start... all free! Get your winning lineups set, and make the right decisions.

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Fantasy Football Matchup Outlooks

Below are some fantasy football outlooks written by our NFL team here at RotoBaller, bringing you their fantasy football analysis and advice on which players to consider starting in Week 16:

Jacory Croskey-Merritt, RB, Washington Commanders

Washington Commanders rookie running back Jacory Croskey-Merritt operated as the team's lead runner in Week 15, with Chris Rodriguez Jr. (groin) ruled out with a groin injury. Croskey-Merritt delivered a strong performance, handling 18 carries for 96 yards and a touchdown in Washington's win over the New York Giants. Jeremy McNichols actually drew the start for Washington, but JCM ended up doubling him in carries. The rookie seventh-rounder found the end zone for the first time since his breakout performance in Week 5 against the Los Angeles Chargers, where he totalled 150 yards and two touchdowns.
 
JCM looked decisive and explosive against the Giants, who notably have one of the worst run defenses in the league, but it was great to see the rookie deliver for fantasy managers who plugged him into their lineups for the first round of the fantasy playoffs. Croskey-Merritt could potentially work himself back into a more significant timeshare with McNichols and Rodriguez upon his return, creating a messy situation to sort through. He remains worth rostering and would project favorably again on Saturday against the Philadelphia Eagles if Rodriguez is out again on a short week.
 
Josh Jacobs, RB, Green Bay Packers
 
Green Bay Packers running back Josh Jacobs (knee) is a non-participant at practice on Wednesday, according to Rob Demovsky of ESPN. Jacobs did not take part in the team's walkthrough practice on Tuesday, either, but he intends to play through his knee issue again in a crucial Week 16 divisional rematch against the Chicago Bears this Saturday night. The 27-year-old has been battling a knee injury since Week 11, and he sat out the Week 12 win over the Minnesota Vikings.
 
He was questionable going into last Sunday's loss to the Denver Broncos, but he ultimately played and had a rushing and receiving touchdown. Jacobs is also listed with an ankle injury, but his knee is the more serious ailment. He might not end up practicing much, if at all, this week, but the expectation is that he'll be ready to go on Saturday. Still, Emanuel Wilson isn't a bad speculative waiver-wire pickup in case Jacobs is ruled out. Jacobs has been a must-start RB1 in fantasy all year with 14 total touchdowns in 13 games, but he's literally limping to the finish line.
 
De'Von Achane, RB, Miami Dolphins
 
Miami Dolphins running back De'Von Achane recorded 12 carries for 60 yards to go with six receptions (six targets) for 67 yards as a receiver in Monday night's loss to the Pittsburgh Steelers. Achane ran efficiently, marking his fifth straight game with at least five yards per carry. The star running back also got involved as a receiver again after recording just one catch over the past two games, leading Miami in receiving yards and notching his sixth game with at least six receptions this season.
 
Despite the Dolphins struggling to move the ball all night in the cold weather in Pittsburgh, Achane was still able to manage 127 total yards and deliver another strong performance for fantasy managers. The 24-year-old profiles as one of the best options in all of fantasy for next week's matchup against the porous Cincinnati Bengals defense.
 
Saquon Barkley, RB, Philadelphia Eagles
 
Philadelphia Eagles running back Saquon Barkley (stinger) is back at practice on Wednesday after he was listed as a non-participant due to a stinger on Tuesday, according to Cayden Steele of NJ Advance Media. Barkley suffered a stinger in Sunday's blowout win over the Las Vegas Raiders, but his return to practice on Wednesday bodes well for his chances of playing on Saturday versus the division-rival Washington Commanders.
 
Although the 28-year-old wasn't quite as good as he was in the Monday night overtime loss to the Los Angeles Chargers in Week 14, he scored a rushing touchdown for the second straight week and had 20-plus carries for the fifth time in 2025. Barkley has had 20-plus rushing attempts in four of six games since the team's bye, as the Eagles make a point to involve last year's leading rusher more to spark their struggling offense. As long as Barkley is active in Week 16, which he should be, he will be a must-start in all fantasy football lineups against a poor Washington defense. UPDATE: Barkley was a full-go at Wednesday's practice.
 
Nick Chubb, RB, Houston Texans
 
Houston Texans veteran running back Nick Chubb (ribs) was back at practice on Wednesday after missing the team's Week 15 win over the Cardinals. Rookie Woody Marks (ankle) was forced out of the blowout win with an ankle injury and was not spotted at Wednesday's practice, so Chubb could see an uptick in volume in a favorable Week 16 matchup with the Raiders, assuming his ribs respond well to a week of practice.
 
Head Coach DeMeco Ryans noted on Monday that Marks could have returned to the game if the outcome had been more in doubt, so his absence on Wednesday could be viewed as an abundance of caution. Fantasy managers will need to monitor this somewhat cloudy backfield situation because if any Texans running back enters Sunday's game in a position to handle the bulk of carries, they should be able to convert that into fantasy success, and this includes popular waiver pickup Jawhar Jordan, who just put up 101 yards on 15 carries against the Cardinals. UPDATE: Chubb was limited in his return to practice on Wednesday.

 

Who Should I Start Tool

You can also see the Who Should I Start tool here.

Week 16 Player Decisions. Today's focus is on specific players - Derrick Henry, Jacory Croskey-Merritt, Jonathan Taylor, Josh Jacobs, Chase Brown, Isiah Pacheco, De'Von Achane, Saquon Barkley, Nick Chubb. These are some of the most common searches for fantasy football lineups in Week 16.

Using The Tool. This is a simple tool but very powerful. The first step is to enter the player names that you want to compare. In the first box, search for the first player name. In the second box, search for the second player name. Compare up to four NFL players at once, and then click the Who To Start? button to see who the recommended starts are based on weekly fantasy football matchups.

Improvements For Who Should I Start? You may have noticed that our 'Who Should I Start?' tool has gotten an overhaul. We've added lots of great features for you to give you as much information as possible to win your fantasy football matchups each week. You'll see NFL player tiles with headshots and bye weeks, stats, projections, strength of schedule, players news, and enhanced search results with data to compare with a slick new interface. We hope you enjoy!

How It Works. Each week our RotoBaller staff puts together their weekly fantasy football rankings and projections based on their research. That information is the core data that is powering the decision-making in this tool. When you search for player names, you will only see those players who are ranked. If someone is out for the week, they will not appear in the search results.

Scoring Formats. Fantasy football managers play in various types of leagues, and this tool allows you to choose whether it's PPR scoring, Half-PPR scoring, or Standard (Non-PPR) scoring. The second thing you want to do, is to select the scoring format. There are three small radio buttons (small circle), so click on the scoring format you prefer. The results may vary based on the scoring format you select.

Popular Week 16 Searches. Curious to see some tough lineup decisions for Week 16 (2025)? Below you will find a list of some popular Who Should I Start? searches that RotoBaller readers are looking at this week. Click any of the links to see the result and recommendation.

 

Popular Week 16 Searches - Start/Sit Player Comparisons

Below are some popular searches and comparisons from our Who To Start tool for Week 16 for Derrick Henry, Jacory Croskey-Merritt, Jonathan Taylor, Josh Jacobs, Chase Brown, Isiah Pacheco, De'Von Achane, Saquon Barkley, Nick Chubb:

Derrick Henry
vs
Jeremiyah Love
Derrick Henry
vs
Kenneth Walker III
Derrick Henry
vs
Malik Nabers
Derrick Henry
vs
George Pickens
Derrick Henry
vs
Omarion Hampton
Derrick Henry
vs
Brock Bowers
Derrick Henry
vs
Saquon Barkley
Derrick Henry
vs
Nico Collins
Derrick Henry
vs
Justin Jefferson
Derrick Henry
vs
Chase Brown
Derrick Henry
vs
Ashton Jeanty
Derrick Henry
vs
Chris Olave
Derrick Henry
vs
Drake London
Derrick Henry
vs
Josh Jacobs
Derrick Henry
vs
De'Von Achane
Derrick Henry
vs
Josh Allen
Derrick Henry
vs
Trey McBride
Derrick Henry
vs
A.J. Brown
Derrick Henry
vs
Amon-Ra St. Brown
Derrick Henry
vs
Travis Etienne Jr.
Derrick Henry
vs
Jahmyr Gibbs
Derrick Henry
vs
Bijan Robinson
Derrick Henry
vs
Christian McCaffrey
Derrick Henry
vs
James Cook III
Derrick Henry
vs
Bucky Irving
Derrick Henry
vs
Kyren Williams
Derrick Henry
vs
Breece Hall
Derrick Henry
vs
Javonte Williams
Jacory Croskey-Merritt
vs
Juwan Johnson
Jacory Croskey-Merritt
vs
Fernando Mendoza
Jacory Croskey-Merritt
vs
Mike Washington Jr.
Jacory Croskey-Merritt
vs
Houston Texans
Jacory Croskey-Merritt
vs
Mark Andrews
Jacory Croskey-Merritt
vs
Kayshon Boutte
Jacory Croskey-Merritt
vs
James Conner
Jacory Croskey-Merritt
vs
Jerry Jeudy
Jacory Croskey-Merritt
vs
Travis Hunter
Jacory Croskey-Merritt
vs
Brandon Aiyuk
Jacory Croskey-Merritt
vs
Hunter Henry
Jacory Croskey-Merritt
vs
Rashid Shaheed
Jacory Croskey-Merritt
vs
Tyreek Hill
Jacory Croskey-Merritt
vs
Travis Kelce
Jacory Croskey-Merritt
vs
Deebo Samuel Sr.
Jacory Croskey-Merritt
vs
Isaiah Likely
Jacory Croskey-Merritt
vs
Jalen McMillan
Jacory Croskey-Merritt
vs
Woody Marks
Jacory Croskey-Merritt
vs
C.J. Stroud
Jacory Croskey-Merritt
vs
Rachaad White
Jacory Croskey-Merritt
vs
Jahmyr Gibbs
Jacory Croskey-Merritt
vs
Bijan Robinson
Jacory Croskey-Merritt
vs
Christian McCaffrey
Jacory Croskey-Merritt
vs
James Cook III
Jacory Croskey-Merritt
vs
Ashton Jeanty
Jacory Croskey-Merritt
vs
Omarion Hampton
Jacory Croskey-Merritt
vs
Jeremiyah Love
Jacory Croskey-Merritt
vs
Kenneth Walker III
Jonathan Taylor
vs
Christian McCaffrey
Jonathan Taylor
vs
CeeDee Lamb
Jonathan Taylor
vs
Jaxon Smith-Njigba
Jonathan Taylor
vs
James Cook III
Jonathan Taylor
vs
Ja'Marr Chase
Jonathan Taylor
vs
Amon-Ra St. Brown
Jonathan Taylor
vs
Puka Nacua
Jonathan Taylor
vs
Trey McBride
Jonathan Taylor
vs
Bijan Robinson
Jonathan Taylor
vs
De'Von Achane
Jonathan Taylor
vs
Jahmyr Gibbs
Jonathan Taylor
vs
Drake London
Jonathan Taylor
vs
Ashton Jeanty
Jonathan Taylor
vs
Justin Jefferson
Jonathan Taylor
vs
Saquon Barkley
Jonathan Taylor
vs
Omarion Hampton
Jonathan Taylor
vs
Malik Nabers
Jonathan Taylor
vs
Jeremiyah Love
Jonathan Taylor
vs
Derrick Henry
Jonathan Taylor
vs
Kenneth Walker III
Jonathan Taylor
vs
Travis Etienne Jr.
Jonathan Taylor
vs
Bucky Irving
Jonathan Taylor
vs
Kyren Williams
Jonathan Taylor
vs
Breece Hall
Jonathan Taylor
vs
Javonte Williams
Jonathan Taylor
vs
TreVeyon Henderson
Jonathan Taylor
vs
Cam Skattebo
Jonathan Taylor
vs
Quinshon Judkins
Josh Jacobs
vs
Chris Olave
Josh Jacobs
vs
Josh Allen
Josh Jacobs
vs
Chase Brown
Josh Jacobs
vs
A.J. Brown
Josh Jacobs
vs
Nico Collins
Josh Jacobs
vs
Travis Etienne Jr.
Josh Jacobs
vs
Brock Bowers
Josh Jacobs
vs
Tee Higgins
Josh Jacobs
vs
George Pickens
Josh Jacobs
vs
Bucky Irving
Josh Jacobs
vs
Kenneth Walker III
Josh Jacobs
vs
Rashee Rice
Josh Jacobs
vs
Derrick Henry
Josh Jacobs
vs
Kyren Williams
Josh Jacobs
vs
Jeremiyah Love
Josh Jacobs
vs
Tetairoa McMillan
Josh Jacobs
vs
Malik Nabers
Josh Jacobs
vs
Breece Hall
Josh Jacobs
vs
Omarion Hampton
Josh Jacobs
vs
Garrett Wilson
Josh Jacobs
vs
Jahmyr Gibbs
Josh Jacobs
vs
Bijan Robinson
Josh Jacobs
vs
Christian McCaffrey
Josh Jacobs
vs
James Cook III
Josh Jacobs
vs
Ashton Jeanty
Josh Jacobs
vs
Javonte Williams
Josh Jacobs
vs
TreVeyon Henderson
Josh Jacobs
vs
Cam Skattebo
Chase Brown
vs
Nico Collins
Chase Brown
vs
Chris Olave
Chase Brown
vs
Brock Bowers
Chase Brown
vs
Josh Jacobs
Chase Brown
vs
George Pickens
Chase Brown
vs
Josh Allen
Chase Brown
vs
Kenneth Walker III
Chase Brown
vs
A.J. Brown
Chase Brown
vs
Derrick Henry
Chase Brown
vs
Travis Etienne Jr.
Chase Brown
vs
Jeremiyah Love
Chase Brown
vs
Tee Higgins
Chase Brown
vs
Malik Nabers
Chase Brown
vs
Bucky Irving
Chase Brown
vs
Omarion Hampton
Chase Brown
vs
Rashee Rice
Chase Brown
vs
Saquon Barkley
Chase Brown
vs
Kyren Williams
Chase Brown
vs
Justin Jefferson
Chase Brown
vs
Tetairoa McMillan
Chase Brown
vs
Jahmyr Gibbs
Chase Brown
vs
Bijan Robinson
Chase Brown
vs
Christian McCaffrey
Chase Brown
vs
James Cook III
Chase Brown
vs
Ashton Jeanty
Chase Brown
vs
Breece Hall
Chase Brown
vs
Javonte Williams
Chase Brown
vs
TreVeyon Henderson
Isiah Pacheco
vs
Germie Bernard
Isiah Pacheco
vs
Ted Hurst
Isiah Pacheco
vs
Cade Otton
Isiah Pacheco
vs
Terrance Ferguson
Isiah Pacheco
vs
Jalen Nailor
Isiah Pacheco
vs
Mason Taylor
Isiah Pacheco
vs
Darnell Mooney
Isiah Pacheco
vs
Minnesota Vikings
Isiah Pacheco
vs
Tory Horton
Isiah Pacheco
vs
Emanuel Wilson
Isiah Pacheco
vs
Kyle Williams
Isiah Pacheco
vs
Najee Harris
Isiah Pacheco
vs
Chris Brazzell II
Isiah Pacheco
vs
Los Angeles Chargers
Isiah Pacheco
vs
Tre Tucker
Isiah Pacheco
vs
J.J. McCarthy
Isiah Pacheco
vs
Elic Ayomanor
Isiah Pacheco
vs
Theo Johnson
Isiah Pacheco
vs
Joe Mixon
Isiah Pacheco
vs
Marvin Mims Jr.
Isiah Pacheco
vs
Jahmyr Gibbs
Isiah Pacheco
vs
Bijan Robinson
Isiah Pacheco
vs
Christian McCaffrey
Isiah Pacheco
vs
James Cook III
Isiah Pacheco
vs
Ashton Jeanty
Isiah Pacheco
vs
Omarion Hampton
Isiah Pacheco
vs
Jeremiyah Love
Isiah Pacheco
vs
Kenneth Walker III
De'Von Achane
vs
Trey McBride
De'Von Achane
vs
Drake London
De'Von Achane
vs
Amon-Ra St. Brown
De'Von Achane
vs
Ashton Jeanty
De'Von Achane
vs
James Cook III
De'Von Achane
vs
Justin Jefferson
De'Von Achane
vs
CeeDee Lamb
De'Von Achane
vs
Saquon Barkley
De'Von Achane
vs
Jonathan Taylor
De'Von Achane
vs
Omarion Hampton
De'Von Achane
vs
Christian McCaffrey
De'Von Achane
vs
Malik Nabers
De'Von Achane
vs
Jaxon Smith-Njigba
De'Von Achane
vs
Jeremiyah Love
De'Von Achane
vs
Ja'Marr Chase
De'Von Achane
vs
Derrick Henry
De'Von Achane
vs
Puka Nacua
De'Von Achane
vs
Kenneth Walker III
De'Von Achane
vs
Bijan Robinson
De'Von Achane
vs
George Pickens
De'Von Achane
vs
Jahmyr Gibbs
De'Von Achane
vs
Travis Etienne Jr.
De'Von Achane
vs
Bucky Irving
De'Von Achane
vs
Kyren Williams
De'Von Achane
vs
Breece Hall
De'Von Achane
vs
Javonte Williams
De'Von Achane
vs
TreVeyon Henderson
De'Von Achane
vs
Cam Skattebo
Saquon Barkley
vs
Justin Jefferson
Saquon Barkley
vs
Omarion Hampton
Saquon Barkley
vs
Ashton Jeanty
Saquon Barkley
vs
Malik Nabers
Saquon Barkley
vs
Drake London
Saquon Barkley
vs
Jeremiyah Love
Saquon Barkley
vs
De'Von Achane
Saquon Barkley
vs
Derrick Henry
Saquon Barkley
vs
Trey McBride
Saquon Barkley
vs
Kenneth Walker III
Saquon Barkley
vs
Amon-Ra St. Brown
Saquon Barkley
vs
George Pickens
Saquon Barkley
vs
James Cook III
Saquon Barkley
vs
Brock Bowers
Saquon Barkley
vs
CeeDee Lamb
Saquon Barkley
vs
Nico Collins
Saquon Barkley
vs
Jonathan Taylor
Saquon Barkley
vs
Chase Brown
Saquon Barkley
vs
Christian McCaffrey
Saquon Barkley
vs
Chris Olave
Saquon Barkley
vs
Jahmyr Gibbs
Saquon Barkley
vs
Bijan Robinson
Saquon Barkley
vs
Travis Etienne Jr.
Saquon Barkley
vs
Bucky Irving
Saquon Barkley
vs
Kyren Williams
Saquon Barkley
vs
Breece Hall
Saquon Barkley
vs
Javonte Williams
Saquon Barkley
vs
TreVeyon Henderson

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SP
RP

RANKINGS

QB
RB
WR
TE
K
DEF